iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023802

Ensembl Protein ID

ENSCSAP00000015544.1

UniProt Accession

A0A0D9S3V5; A0A0D9S3V5_CHLSB

Genbank Protein ID

ENSCSAP00000015544

Protein Name

Nitric oxide synthase-interacting protein

Genbank Nucleotide ID

AQIB01135593

Gene Name

NOSIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000002499.1	ENSCSAT00000000517.1	ENSCSAP00000015544.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.60e-16	58.1	77	116

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk 41
           v ++ +C +sl++ +dPvv+p+G+ y+r++I +++ +++k
   Q: 77   VKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKK 116
           567789*****************************99887 PP

Organism

Chlorocebus sabaeus

Functional Description
(View)

Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.

Protein Sequence
(Fasta)

MPSAGRKWAE RRGKIVLLSG VGAQLKKRPR DWESFGRMTR HGKNCTAGAV YTYHEKKKDT 60
AASGYGTQNI RLSRDAVKDF DCCCLSLQPC HDPVVTPDGY LYEREAILEY ILHQKKEIAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGAACCTT CTATTTGCCA CTCACGTTTC CGAAGGGAGA AAGAGAAGAG AGGACTTGAG 60
CAAGCCAGGC GAGGCACTTC CGCAACTAGG GGCAGCTCTA CTTCCGATGC CTTCTGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF15906--zf-NOSIP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003723--F:RNA binding
GO:0051001--P:negative regulation of nitric-oxide synthase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000769	Aegilops tauschii	46.51	1.00e-16	81.30
IUUC-Aml-002069	Ailuropoda melanoleuca	89.81	4.00e-161	560.00
IUUC-Atr-002661	Amborella trichopoda	32.53	3.00e-31	128.00
IUUC-Aca-004630	Anolis carolinensis	76.41	3.00e-137	481.00
IUUC-Aly-006316	Arabidopsis lyrata	30.72	4.00e-29	121.00
IUUC-Ath-007000	Arabidopsis thaliana	30.39	1.00e-28	120.00
IUUC-Acl-008175	Aspergillus clavatus	35.40	8.00e-07	48.10
IUUC-Afl-008440	Aspergillus flavus	34.19	2.00e-06	46.60
IUUC-Afu-009012	Aspergillus fumigatus	35.65	6.00e-07	48.50
IUUC-Ani-009153	Aspergillus nidulans	31.20	3.00e-03	36.20
IUUC-Ang-009556	Aspergillus niger	34.78	2.00e-06	47.00
IUUC-Aor-009892	Aspergillus oryzae	34.19	3.00e-06	46.20
IUUC-Ate-010473	Aspergillus terreus	35.37	2.00e-04	41.20
IUUC-Ame-011874	Astyanax mexicanus	63.14	2.00e-109	388.00
IUUC-Bgr-012090	Blumeria graminis	27.82	2.00e-07	49.70
IUUC-Bta-012956	Bos taurus	94.37	6.00e-169	586.00
IUUC-Bci-013897	Botrytis cinerea	42.50	1.00e-09	57.40
IUUC-Bdi-014968	Brachypodium distachyon	30.27	6.00e-34	137.00
IUUC-Bol-015578	Brassica oleracea	30.59	8.00e-34	137.00
IUUC-Bra-017234	Brassica rapa	30.59	8.00e-34	137.00
IUUC-Cel-018637	Caenorhabditis elegans	40.12	8.00e-56	210.00
IUUC-Cja-019632	Callithrix jacchus	98.01	7.00e-177	612.00
IUUC-Cfa-020192	Canis familiaris	90.77	0.00e+00	627.00
IUUC-Cpo-021939	Cavia porcellus	88.70	1.00e-154	538.00
IUUC-Cre-023005	Chlamydomonas reinhardtii	33.89	6.00e-43	167.00
IUUC-Cho-024637	Choloepus hoffmanni	74.65	2.00e-79	288.00
IUUC-Cin-025180	Ciona intestinalis	51.66	4.00e-85	307.00
IUUC-Csv-026206	Ciona savignyi	47.87	1.00e-42	165.00
IUUC-Cgl-026696	Colletotrichum gloeosporioides	24.10	8.00e-12	64.70
IUUC-Cne-026827	Cryptococcus neoformans	36.36	1.00e-06	47.80
IUUC-Dre-028092	Danio rerio	64.29	9.00e-117	412.00
IUUC-Dno-029501	Dasypus novemcinctus	80.12	2.00e-140	491.00
IUUC-Dor-030542	Dipodomys ordii	90.43	4.00e-163	566.00
IUUC-Dse-031188	Dothistroma septosporum	23.88	1.00e-14	73.60
IUUC-Dme-031734	Drosophila melanogaster	48.54	7.00e-79	286.00
IUUC-Eca-033577	Equus caballus	93.69	5.00e-169	586.00
IUUC-Fca-035761	Felis catus	93.36	3.00e-167	580.00
IUUC-Fox-037703	Fusarium oxysporum	26.91	3.00e-14	72.40
IUUC-Fso-038208	Fusarium solani	26.97	5.00e-13	68.60
IUUC-Gmo-038523	Gadus morhua	59.90	4.00e-61	227.00
IUUC-Ggr-040087	Gaeumannomyces graminis	41.03	7.00e-10	57.80
IUUC-Gac-042621	Gasterosteus aculeatus	59.75	3.00e-108	384.00
IUUC-Gma-042698	Glycine max	31.51	1.00e-32	133.00
IUUC-Ggo-045357	Gorilla gorilla	99.34	2.00e-178	617.00
IUUC-Hsa-046195	Homo sapiens	99.34	2.00e-178	617.00
IUUC-Hvu-047174	Hordeum vulgare	31.65	4.00e-35	141.00
IUUC-Itr-048487	Ictidomys tridecemlineatus	93.69	2.00e-162	564.00
IUUC-Lch-050569	Latimeria chalumnae	68.93	2.00e-116	411.00
IUUC-Lpe-050992	Leersia perrieri	35.96	4.00e-23	102.00
IUUC-Loc-052522	Lepisosteus oculatus	69.67	1.00e-115	409.00
IUUC-Lma-053254	Leptosphaeria maculans	25.50	4.00e-13	68.90
IUUC-Laf-053397	Loxodonta africana	93.40	5.00e-167	579.00
IUUC-Mcc-054681	Macaca mulatta	98.82	0.00e+00	688.00
IUUC-Meu-056723	Macropus eugenii	83.50	5.00e-151	526.00
IUUC-Mor-056961	Magnaporthe oryzae	26.13	3.00e-12	65.90
IUUC-Mpo-057359	Magnaporthe poae	25.14	3.00e-07	48.90
IUUC-Mtr-058063	Medicago truncatula	32.42	4.00e-34	138.00
IUUC-Mla-059004	Melampsora laricipopulina	30.35	9.00e-26	110.00
IUUC-Mvi-060460	Microbotryum violaceum	29.76	8.00e-27	114.00
IUUC-Mmr-060847	Microcebus murinus	97.01	2.00e-174	604.00
IUUC-Mdo-062480	Monodelphis domestica	83.50	9.00e-151	525.00
IUUC-Mmu-063809	Mus musculus	90.37	3.00e-161	560.00
IUUC-Mac-064870	Musa acuminata	31.85	9.00e-34	137.00
IUUC-Mpu-066322	Mustela putorius furo	92.48	1.00e-173	602.00
IUUC-Mlu-067556	Myotis lucifugus	91.12	6.00e-156	543.00
IUUC-Nfi-068440	Neosartorya fischeri	35.96	6.00e-07	48.50
IUUC-Ncr-068898	Neurospora crassa	38.46	1.00e-07	50.80
IUUC-Nle-070049	Nomascus leucogenys	99.37	0.00e+00	646.00
IUUC-Opr-070972	Ochotona princeps	87.87	2.00e-154	537.00
IUUC-Ont-071682	Oreochromis niloticus	65.89	7.00e-117	413.00
IUUC-Oan-073296	Ornithorhynchus anatinus	71.74	4.00e-33	133.00
IUUC-Ocu-074218	Oryctolagus cuniculus	88.93	5.00e-133	466.00
IUUC-Oba-075284	Oryza barthii	32.76	9.00e-34	137.00
IUUC-Obr-076651	Oryza brachyantha	32.19	3.00e-36	145.00
IUUC-Ogl-077899	Oryza glaberrima	32.76	9.00e-34	137.00
IUUC-Ogu-078477	Oryza glumaepatula	33.11	5.00e-34	137.00
IUUC-Oin-080011	Oryza indica	32.76	1.00e-33	137.00
IUUC-Olo-080545	Oryza longistaminata	32.43	6.00e-27	115.00
IUUC-Ome-081543	Oryza meridionalis	32.76	1.00e-33	137.00
IUUC-Oni-082955	Oryza nivara	32.76	1.00e-33	137.00
IUUC-Opu-083565	Oryza punctata	32.19	9.00e-34	137.00
IUUC-Oru-084474	Oryza rufipogon	32.76	1.00e-33	137.00
IUUC-Osa-085913	Oryza sativa	32.76	1.00e-33	137.00
IUUC-Ola-086851	Oryzias latipes	66.78	2.00e-119	421.00
IUUC-Olu-087724	Ostreococcus lucimarinus	31.43	3.00e-11	62.40
IUUC-Oga-087970	Otolemur garnettii	94.70	5.00e-170	589.00
IUUC-Oar-089756	Ovis aries	90.76	2.00e-157	547.00
IUUC-Ptr-091485	Pan troglodytes	98.01	1.00e-174	605.00
IUUC-Pan-091832	Papio anubis	99.67	5.00e-179	619.00
IUUC-Pma-094551	Petromyzon marinus	62.21	2.00e-106	378.00
IUUC-Pno-094830	Phaeosphaeria nodorum	35.29	5.00e-09	55.10
IUUC-Ppa-095255	Physcomitrella patens	30.33	3.00e-32	131.00
IUUC-Pfo-096373	Poecilia formosa	65.03	1.00e-116	412.00
IUUC-Pab-098247	Pongo abelii	98.51	0.00e+00	680.00
IUUC-Pop-099186	Populus trichocarpa	31.51	1.00e-31	130.00
IUUC-Pca-100677	Procavia capensis	89.82	4.00e-136	476.00
IUUC-Ppe-101403	Prunus persica	30.24	3.00e-32	131.00
IUUC-Pva-103000	Pteropus vampyrus	93.02	2.00e-167	581.00
IUUC-Pgr-103663	Puccinia graminis	30.56	1.00e-31	130.00
IUUC-Ptt-103712	Puccinia triticina	40.00	6.00e-09	54.30
IUUC-Pte-104287	Pyrenophora teres	26.41	2.00e-17	83.20
IUUC-Pyt-104579	Pyrenophora triticirepentis	27.21	4.00e-15	75.50
IUUC-Rno-106069	Rattus norvegicus	91.36	2.00e-162	564.00
IUUC-Sha-106553	Sarcophilus harrisii	83.17	5.00e-150	523.00
IUUC-Smo-108874	Selaginella moellendorffii	32.89	2.00e-37	149.00
IUUC-Sit-110307	Setaria italica	32.76	3.00e-33	135.00
IUUC-Sly-111094	Solanum lycopersicum	31.35	7.00e-34	137.00
IUUC-Stu-112363	Solanum tuberosum	32.01	7.00e-34	137.00
IUUC-Sar-113480	Sorex araneus	92.03	4.00e-154	536.00
IUUC-Sbi-113939	Sorghum bicolor	32.76	9.00e-34	137.00
IUUC-Ssc-115644	Sus scrofa	94.68	5.00e-170	589.00
IUUC-Tru-118781	Takifugu rubripes	66.12	5.00e-120	423.00
IUUC-Tni-119672	Tetraodon nigroviridis	75.86	1.00e-35	140.00
IUUC-Tca-121795	Theobroma cacao	32.44	4.00e-36	144.00
IUUC-Tre-122037	Trichoderma reesei	36.36	3.00e-08	52.80
IUUC-Tvi-122524	Trichoderma virens	27.49	6.00e-17	81.60
IUUC-Tae-122828	Triticum aestivum	31.99	3.00e-35	142.00
IUUC-Tur-126387	Triticum urartu	32.05	1.00e-28	121.00
IUUC-Tme-127111	Tuber melanosporum	40.00	2.00e-09	56.60
IUUC-Ttr-128227	Tursiops truncatus	93.02	2.00e-166	577.00
IUUC-Vda-129924	Verticillium dahliae	26.56	3.00e-14	72.80
IUUC-Vpa-130802	Vicugna pacos	95.51	2.00e-44	172.00
IUUC-Vvi-131105	Vitis vinifera	33.22	2.00e-34	139.00
IUUC-Xtr-132830	Xenopus tropicalis	65.94	6.00e-122	430.00
IUUC-Xma-133618	Xiphophorus maculatus	65.46	8.00e-111	392.00
IUUC-Zma-135389	Zea mays	31.38	8.00e-33	134.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence