iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062579

UUCD1 version

UUC-MoD-01124

Ensembl Protein ID

ENSMODP00000025829.3

UniProt Accession

F7EMC3; F7EMC3_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000020647.3	ENSMODT00000026290.3	ENSMODP00000025829.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-98	329.8	35	364

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l  +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 35   FGLVNFGNTCYCNSVLQALYFCRPFRENVLA-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 116
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l   ++++k+e+++ + ++ +++++ +++k + ++++++Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 117  MQQDAHEFLNYLLNTIADIL---QEEKKQEKQNGKLKNGNMNEPVENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 202
           ********************...44555555555666677778889999999************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 203  EQNT-----SITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 284
           ****.....9**********************************************************************66555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts++  ++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 285  TSSDA-VNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 364
           77554.4459***************************.888*******************999*****************97 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MTVRNIASIC NMGTNASALE KDIGPEQFPI NEHYFGLVNF GNTCYCNSVL QALYFCRPFR 60
ENVLAYKAQQ KKKENLLTCL ADLFHSIATQ KKKVGVIPPK KFISRLRKEN DLFDNYMQQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGTCC GAAACATCGC CTCCATCTGT AATATGGTGA GTACTAGCTG GCTTGGAGGT 60
AGGCTTGAAG GAATGAGGAG CTAAAGGAAT GAAAGAAAGC CCAGGAAGAA CAAACCTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008343--P:adult feeding behavior
GO:0001662--P:behavioral fear response
GO:0048149--P:behavioral response to ethanol
GO:0016579--P:protein deubiquitination
GO:0032228--P:regulation of synaptic transmission, GABAergic
GO:0060013--P:righting reflex
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mdo:100018316

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000193	Aegilops tauschii	60.00	1.00e-125	442.00
IUUC-Aml-002353	Ailuropoda melanoleuca	98.08	0.00e+00	702.00
IUUC-Atr-002650	Amborella trichopoda	59.56	9.00e-126	442.00
IUUC-Apl-003380	Anas platyrhynchos	95.63	0.00e+00	689.00
IUUC-Aca-005031	Anolis carolinensis	97.27	0.00e+00	749.00
IUUC-Aly-005830	Arabidopsis lyrata	58.92	1.00e-123	436.00
IUUC-Ath-006663	Arabidopsis thaliana	59.07	6.00e-127	446.00
IUUC-Ago-007871	Ashbya gossypii	38.57	4.00e-49	189.00
IUUC-Ame-010862	Astyanax mexicanus	94.58	0.00e+00	723.00
IUUC-Bta-013023	Bos taurus	98.34	0.00e+00	699.00
IUUC-Bdi-014008	Brachypodium distachyon	60.22	3.00e-125	441.00
IUUC-Bol-015138	Brassica oleracea	58.87	2.00e-125	441.00
IUUC-Bra-017483	Brassica rapa	60.34	5.00e-126	443.00
IUUC-Cel-018379	Caenorhabditis elegans	62.16	2.00e-144	505.00
IUUC-Cja-018956	Callithrix jacchus	97.28	0.00e+00	697.00
IUUC-Cfa-021064	Canis familiaris	99.15	0.00e+00	688.00
IUUC-Cpo-022443	Cavia porcellus	98.88	0.00e+00	697.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.65	8.00e-100	357.00
IUUC-Csa-023841	Chlorocebus sabaeus	99.73	0.00e+00	722.00
IUUC-Cin-025659	Ciona intestinalis	56.60	2.00e-129	455.00
IUUC-Csv-025828	Ciona savignyi	54.00	9.00e-123	433.00
IUUC-Cne-026900	Cryptococcus neoformans	41.91	4.00e-60	226.00
IUUC-Dre-028230	Danio rerio	94.34	0.00e+00	723.00
IUUC-Dno-029209	Dasypus novemcinctus	97.26	0.00e+00	700.00
IUUC-Dme-032038	Drosophila melanogaster	81.28	5.00e-100	357.00
IUUC-Eca-033721	Equus caballus	99.44	0.00e+00	694.00
IUUC-Eeu-034916	Erinaceus europaeus	98.98	9.00e-163	565.00
IUUC-Fca-036299	Felis catus	97.27	0.00e+00	699.00
IUUC-Fox-037682	Fusarium oxysporum	42.01	1.00e-73	271.00
IUUC-Fso-038299	Fusarium solani	37.07	2.00e-74	273.00
IUUC-Gmo-038611	Gadus morhua	94.07	0.00e+00	693.00
IUUC-Ggr-039806	Gaeumannomyces graminis	42.55	2.00e-75	276.00
IUUC-Gga-041157	Gallus gallus	98.63	0.00e+00	712.00
IUUC-Gac-041764	Gasterosteus aculeatus	93.39	0.00e+00	705.00
IUUC-Gma-042927	Glycine max	60.33	1.00e-127	449.00
IUUC-Ggo-044659	Gorilla gorilla	97.55	0.00e+00	701.00
IUUC-Hsa-046156	Homo sapiens	99.73	0.00e+00	722.00
IUUC-Hvu-047692	Hordeum vulgare	59.45	2.00e-123	435.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	99.73	0.00e+00	722.00
IUUC-Kpa-049250	Komagataella pastoris	44.83	1.00e-69	257.00
IUUC-Lch-049969	Latimeria chalumnae	96.72	0.00e+00	684.00
IUUC-Lpe-051368	Leersia perrieri	59.45	8.00e-123	433.00
IUUC-Loc-052479	Lepisosteus oculatus	90.98	0.00e+00	692.00
IUUC-Laf-054085	Loxodonta africana	99.73	0.00e+00	722.00
IUUC-Mcc-055566	Macaca mulatta	97.81	0.00e+00	700.00
IUUC-Mpo-057424	Magnaporthe poae	41.54	1.00e-75	277.00
IUUC-Mtr-057715	Medicago truncatula	60.33	4.00e-128	450.00
IUUC-Mla-059142	Melampsora laricipopulina	54.45	6.00e-96	345.00
IUUC-Mga-059575	Meleagris gallopavo	98.59	0.00e+00	686.00
IUUC-Mvi-060357	Microbotryum violaceum	53.96	3.00e-77	283.00
IUUC-Mmu-063611	Mus musculus	99.73	0.00e+00	722.00
IUUC-Mac-065323	Musa acuminata	60.11	2.00e-124	438.00
IUUC-Mpu-066038	Mustela putorius furo	99.72	0.00e+00	697.00
IUUC-Mlu-068183	Myotis lucifugus	97.80	0.00e+00	704.00
IUUC-Nle-069330	Nomascus leucogenys	99.73	0.00e+00	722.00
IUUC-Opr-070980	Ochotona princeps	99.44	0.00e+00	696.00
IUUC-Ont-072134	Oreochromis niloticus	95.12	0.00e+00	728.00
IUUC-Oan-073583	Ornithorhynchus anatinus	93.52	0.00e+00	684.00
IUUC-Ocu-074923	Oryctolagus cuniculus	99.44	0.00e+00	694.00
IUUC-Oba-075220	Oryza barthii	59.73	2.00e-123	434.00
IUUC-Obr-076208	Oryza brachyantha	57.65	3.00e-120	424.00
IUUC-Ogl-077216	Oryza glaberrima	59.73	2.00e-123	434.00
IUUC-Ogu-078836	Oryza glumaepatula	59.73	2.00e-123	434.00
IUUC-Oin-079522	Oryza indica	59.73	2.00e-123	434.00
IUUC-Olo-080882	Oryza longistaminata	59.73	2.00e-123	434.00
IUUC-Ome-081549	Oryza meridionalis	59.73	2.00e-123	434.00
IUUC-Oni-082982	Oryza nivara	59.73	2.00e-123	434.00
IUUC-Opu-083532	Oryza punctata	59.73	2.00e-123	435.00
IUUC-Oru-084568	Oryza rufipogon	59.73	2.00e-123	434.00
IUUC-Osa-085299	Oryza sativa	59.73	2.00e-123	434.00
IUUC-Ola-086546	Oryzias latipes	93.66	0.00e+00	705.00
IUUC-Olu-087809	Ostreococcus lucimarinus	48.44	2.00e-81	295.00
IUUC-Oga-088073	Otolemur garnettii	99.44	0.00e+00	694.00
IUUC-Oar-089248	Ovis aries	99.72	0.00e+00	696.00
IUUC-Ptr-090814	Pan troglodytes	99.73	0.00e+00	722.00
IUUC-Pan-091753	Papio anubis	99.73	0.00e+00	722.00
IUUC-Psi-094012	Pelodiscus sinensis	99.15	0.00e+00	689.00
IUUC-Pma-094388	Petromyzon marinus	89.54	0.00e+00	689.00
IUUC-Ppa-095415	Physcomitrella patens	59.03	1.00e-127	449.00
IUUC-Pfo-097369	Poecilia formosa	95.12	0.00e+00	728.00
IUUC-Pab-098594	Pongo abelii	99.72	0.00e+00	700.00
IUUC-Pop-099798	Populus trichocarpa	59.84	8.00e-127	446.00
IUUC-Pca-100913	Procavia capensis	83.38	2.00e-159	554.00
IUUC-Ppe-101474	Prunus persica	59.56	1.00e-126	446.00
IUUC-Pva-102892	Pteropus vampyrus	99.72	0.00e+00	697.00
IUUC-Rno-104909	Rattus norvegicus	99.45	0.00e+00	721.00
IUUC-Sha-107400	Sarcophilus harrisii	100.00	0.00e+00	699.00
IUUC-Smo-109064	Selaginella moellendorffii	60.06	1.00e-120	426.00
IUUC-Sit-109700	Setaria italica	58.74	9.00e-123	433.00
IUUC-Sly-111210	Solanum lycopersicum	60.27	4.00e-127	447.00
IUUC-Stu-112398	Solanum tuberosum	59.89	1.00e-126	446.00
IUUC-Sbi-114562	Sorghum bicolor	58.74	4.00e-124	437.00
IUUC-Ssc-115550	Sus scrofa	99.72	0.00e+00	697.00
IUUC-Tgu-116800	Taeniopygia guttata	98.63	0.00e+00	712.00
IUUC-Tru-118212	Takifugu rubripes	95.12	0.00e+00	730.00
IUUC-Tni-120071	Tetraodon nigroviridis	95.12	0.00e+00	730.00
IUUC-Tca-121329	Theobroma cacao	60.22	4.00e-127	447.00
IUUC-Tae-125280	Triticum aestivum	60.27	1.00e-126	446.00
IUUC-Tur-126563	Triticum urartu	60.00	4.00e-126	444.00
IUUC-Uma-129409	Ustilago maydis	48.78	7.00e-81	295.00
IUUC-Vpa-130590	Vicugna pacos	95.21	0.00e+00	654.00
IUUC-Vvi-131371	Vitis vinifera	59.56	2.00e-126	445.00
IUUC-Xma-133111	Xiphophorus maculatus	94.85	0.00e+00	727.00
IUUC-Yli-134632	Yarrowia lipolytica	45.21	5.00e-79	289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence