iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089248

Ensembl Protein ID

ENSOARP00000019927.1

UniProt Accession

W5QB32; W5QB32_SHEEP

Genbank Protein ID

ENSOARP00000019927

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01098539

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000018560.1	ENSOART00000020202.1	ENSOARP00000019927.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-98	330.2	41	370

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l  +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 41   FGLVNFGNTCYCNSVLQALYFCRPFRENVLA-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 122
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l   ++++k+e+++ + ++ +++++ +++k + ++++++Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 123  MQQDAHEFLNYLLNTIADIL---QEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 208
           ********************...34555555555556666677788888888************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 209  EQNT-----SITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 290
           ****.....9**********************************************************************66555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts++  ++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 291  TSSDA-VNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 370
           77554.4459***************************.888*******************999*****************97 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MHFEGRAPQN TSLHCSPQGT NASALEKDIG PEQFPINEHY FGLVNFGNTC YCNSVLQALY 60
FCRPFRENVL AYKAQQKKKE NLLTCLADLF HSIATQKKKV GVIPPKKFIS RLRKENDLFD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCATTTTG AAGGCAGAGC CCCTCAAAAC ACCTCGCTAC ATTGCTCTCC CCAGGTGGGT 60
GCAGTGGGTG GGAAGGAAAA CAAATGGCCT AGGTTTGAAT GGCTGACCAA GGTAGGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008343--P:adult feeding behavior
GO:0001662--P:behavioral fear response
GO:0048149--P:behavioral response to ethanol
GO:0016579--P:protein deubiquitination
GO:0032228--P:regulation of synaptic transmission, GABAergic
GO:0060013--P:righting reflex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000193	Aegilops tauschii	59.89	8.00e-125	439.00
IUUC-Aml-002353	Ailuropoda melanoleuca	99.16	0.00e+00	700.00
IUUC-Atr-002650	Amborella trichopoda	59.45	7.00e-125	440.00
IUUC-Apl-003380	Anas platyrhynchos	98.59	0.00e+00	687.00
IUUC-Aca-005031	Anolis carolinensis	97.18	0.00e+00	724.00
IUUC-Aly-005830	Arabidopsis lyrata	58.81	8.00e-123	433.00
IUUC-Ath-006663	Arabidopsis thaliana	58.95	1.00e-125	442.00
IUUC-Ago-007871	Ashbya gossypii	38.57	6.00e-49	189.00
IUUC-Ame-010862	Astyanax mexicanus	94.68	0.00e+00	698.00
IUUC-Bta-013023	Bos taurus	99.72	0.00e+00	700.00
IUUC-Bdi-014008	Brachypodium distachyon	60.44	3.00e-124	437.00
IUUC-Bol-015138	Brassica oleracea	58.49	7.00e-124	436.00
IUUC-Bra-017483	Brassica rapa	60.23	2.00e-125	441.00
IUUC-Cel-018379	Caenorhabditis elegans	62.22	9.00e-145	506.00
IUUC-Cja-018956	Callithrix jacchus	99.44	0.00e+00	698.00
IUUC-Cfa-021064	Canis familiaris	99.15	0.00e+00	689.00
IUUC-Cpo-022443	Cavia porcellus	99.72	0.00e+00	698.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.52	7.00e-99	353.00
IUUC-Csa-023841	Chlorocebus sabaeus	100.00	0.00e+00	698.00
IUUC-Cne-026900	Cryptococcus neoformans	41.91	4.00e-60	226.00
IUUC-Dre-028230	Danio rerio	94.15	0.00e+00	697.00
IUUC-Dno-029209	Dasypus novemcinctus	99.16	0.00e+00	698.00
IUUC-Dme-032038	Drosophila melanogaster	81.28	9.00e-100	357.00
IUUC-Eca-033721	Equus caballus	99.72	0.00e+00	694.00
IUUC-Eeu-034916	Erinaceus europaeus	98.64	2.00e-162	564.00
IUUC-Fca-036299	Felis catus	100.00	0.00e+00	700.00
IUUC-Fox-037682	Fusarium oxysporum	42.32	4.00e-74	272.00
IUUC-Fso-038299	Fusarium solani	37.07	2.00e-74	273.00
IUUC-Gmo-038611	Gadus morhua	94.63	0.00e+00	692.00
IUUC-Ggr-039806	Gaeumannomyces graminis	42.24	4.00e-75	276.00
IUUC-Gga-041157	Gallus gallus	98.59	0.00e+00	687.00
IUUC-Gac-041764	Gasterosteus aculeatus	95.49	0.00e+00	697.00
IUUC-Gma-043828	Glycine max	60.55	9.00e-127	446.00
IUUC-Ggo-044659	Gorilla gorilla	98.35	0.00e+00	698.00
IUUC-Hsa-046156	Homo sapiens	100.00	0.00e+00	698.00
IUUC-Hvu-047692	Hordeum vulgare	58.74	9.00e-123	432.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	100.00	0.00e+00	698.00
IUUC-Kpa-049250	Komagataella pastoris	44.83	1.00e-69	257.00
IUUC-Lch-049969	Latimeria chalumnae	96.61	0.00e+00	659.00
IUUC-Lpe-051368	Leersia perrieri	58.58	1.00e-121	429.00
IUUC-Loc-052479	Lepisosteus oculatus	90.96	0.00e+00	668.00
IUUC-Laf-054085	Loxodonta africana	100.00	0.00e+00	698.00
IUUC-Mcc-055566	Macaca mulatta	98.89	0.00e+00	699.00
IUUC-Mpo-057424	Magnaporthe poae	42.86	4.00e-75	276.00
IUUC-Mtr-057715	Medicago truncatula	60.22	4.00e-127	447.00
IUUC-Mla-059142	Melampsora laricipopulina	54.08	6.00e-96	345.00
IUUC-Mga-059575	Meleagris gallopavo	98.32	0.00e+00	692.00
IUUC-Mvi-060357	Microbotryum violaceum	53.96	2.00e-77	284.00
IUUC-Mdo-062579	Monodelphis domestica	99.72	0.00e+00	697.00
IUUC-Mmu-063611	Mus musculus	100.00	0.00e+00	698.00
IUUC-Mac-065323	Musa acuminata	60.56	3.00e-123	434.00
IUUC-Mpu-066038	Mustela putorius furo	99.72	0.00e+00	698.00
IUUC-Mlu-068183	Myotis lucifugus	99.16	0.00e+00	701.00
IUUC-Nle-069330	Nomascus leucogenys	100.00	0.00e+00	698.00
IUUC-Opr-070980	Ochotona princeps	99.72	0.00e+00	696.00
IUUC-Ont-072134	Oreochromis niloticus	94.96	0.00e+00	702.00
IUUC-Oan-073583	Ornithorhynchus anatinus	93.50	0.00e+00	682.00
IUUC-Ocu-074923	Oryctolagus cuniculus	99.44	0.00e+00	695.00
IUUC-Oba-075220	Oryza barthii	59.62	4.00e-122	431.00
IUUC-Obr-076208	Oryza brachyantha	57.53	9.00e-119	419.00
IUUC-Ogl-077216	Oryza glaberrima	59.62	4.00e-122	431.00
IUUC-Ogu-078836	Oryza glumaepatula	59.62	4.00e-122	431.00
IUUC-Oin-079522	Oryza indica	59.62	4.00e-122	431.00
IUUC-Olo-080882	Oryza longistaminata	59.62	4.00e-122	431.00
IUUC-Ome-081549	Oryza meridionalis	59.62	4.00e-122	431.00
IUUC-Oni-082982	Oryza nivara	59.62	4.00e-122	431.00
IUUC-Opu-083532	Oryza punctata	59.62	3.00e-122	431.00
IUUC-Oru-084568	Oryza rufipogon	59.62	4.00e-122	431.00
IUUC-Osa-085299	Oryza sativa	59.62	4.00e-122	431.00
IUUC-Ola-086546	Oryzias latipes	95.00	0.00e+00	707.00
IUUC-Olu-087809	Ostreococcus lucimarinus	48.44	3.00e-81	295.00
IUUC-Oga-088073	Otolemur garnettii	99.72	0.00e+00	694.00
IUUC-Ptr-090814	Pan troglodytes	100.00	0.00e+00	698.00
IUUC-Pan-091753	Papio anubis	100.00	0.00e+00	698.00
IUUC-Psi-094012	Pelodiscus sinensis	99.15	0.00e+00	691.00
IUUC-Ppa-095415	Physcomitrella patens	58.92	1.00e-126	446.00
IUUC-Pfo-097369	Poecilia formosa	94.96	0.00e+00	703.00
IUUC-Pab-098594	Pongo abelii	100.00	0.00e+00	698.00
IUUC-Pop-099798	Populus trichocarpa	60.00	7.00e-126	443.00
IUUC-Pca-100913	Procavia capensis	83.90	3.00e-159	554.00
IUUC-Ppe-101474	Prunus persica	59.73	4.00e-126	444.00
IUUC-Pva-102892	Pteropus vampyrus	100.00	0.00e+00	697.00
IUUC-Pgr-103306	Puccinia graminis	53.31	2.00e-96	347.00
IUUC-Rno-104909	Rattus norvegicus	99.72	0.00e+00	697.00
IUUC-Sce-106367	Saccharomyces cerevisiae	37.63	1.00e-55	211.00
IUUC-Sha-107400	Sarcophilus harrisii	99.16	0.00e+00	697.00
IUUC-Smo-109064	Selaginella moellendorffii	60.22	7.00e-120	423.00
IUUC-Sit-110819	Setaria italica	59.62	1.00e-122	432.00
IUUC-Sly-111210	Solanum lycopersicum	59.62	1.00e-125	442.00
IUUC-Stu-112398	Solanum tuberosum	60.06	4.00e-126	444.00
IUUC-Sbi-114562	Sorghum bicolor	58.79	6.00e-123	433.00
IUUC-Ssc-115550	Sus scrofa	100.00	0.00e+00	697.00
IUUC-Tgu-116800	Taeniopygia guttata	98.59	0.00e+00	687.00
IUUC-Tru-118212	Takifugu rubripes	94.96	0.00e+00	705.00
IUUC-Tni-120071	Tetraodon nigroviridis	94.96	0.00e+00	705.00
IUUC-Tca-121329	Theobroma cacao	60.00	2.00e-126	445.00
IUUC-Tae-124807	Triticum aestivum	59.89	4.00e-125	441.00
IUUC-Tur-126563	Triticum urartu	59.89	3.00e-125	441.00
IUUC-Uma-129409	Ustilago maydis	49.13	2.00e-81	297.00
IUUC-Vpa-130590	Vicugna pacos	95.20	0.00e+00	650.00
IUUC-Vvi-131371	Vitis vinifera	59.73	5.00e-126	444.00
IUUC-Xma-133111	Xiphophorus maculatus	94.96	0.00e+00	703.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence