iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093280

Ensembl Protein ID

ENSPSIP00000016435.1

UniProt Accession

K7G824; K7G824_PELSI

Genbank Protein ID

ENSPSIP00000016435

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01129861

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000014587.1	ENSPSIT00000016511.1	ENSPSIP00000016435.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	75.07	6.00e-160	561.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MEKNGKENHN GLPGHSVKIL PSIGDGPKRL PVHQQHPQNW VPGSGIQAQR VFCPSNLAQR 60
VPVQSQVQKS ALSNQKQSQN LLMQQSRPTS VVQPISGPPA PSKNNEESQQ ASVSAKNQAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAACATGGA GAAAAATGGT AAAGAGAACC ACAATGGGCT TCCTGGTCAC AGTGTTAAGG 60
TAAAGAAGTC TTGTACACTT ACGAGGCAAA CACATTTTAT TTGGTATGAT CAGACAAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	64.54	1.00e-106	378.00
IUUC-Aml-001426	Ailuropoda melanoleuca	75.20	1.00e-165	575.00
IUUC-Atr-002453	Amborella trichopoda	64.54	1.00e-108	385.00
IUUC-Apl-003626	Anas platyrhynchos	76.73	7.00e-171	592.00
IUUC-Aca-004602	Anolis carolinensis	71.39	5.00e-163	566.00
IUUC-Aly-005878	Arabidopsis lyrata	65.69	5.00e-106	376.00
IUUC-Ath-007117	Arabidopsis thaliana	66.79	2.00e-105	374.00
IUUC-Acl-008199	Aspergillus clavatus	58.21	2.00e-88	318.00
IUUC-Afl-008419	Aspergillus flavus	49.43	3.00e-88	318.00
IUUC-Afu-008751	Aspergillus fumigatus	58.21	9.00e-88	316.00
IUUC-Ani-009181	Aspergillus nidulans	57.09	4.00e-91	327.00
IUUC-Ang-009787	Aspergillus niger	58.56	4.00e-88	317.00
IUUC-Aor-009980	Aspergillus oryzae	49.43	3.00e-88	318.00
IUUC-Ate-010286	Aspergillus terreus	58.21	3.00e-88	318.00
IUUC-Ame-010849	Astyanax mexicanus	69.77	8.00e-129	453.00
IUUC-Bgr-012110	Blumeria graminis	61.98	2.00e-90	325.00
IUUC-Bta-013474	Bos taurus	73.44	2.00e-164	571.00
IUUC-Bci-013756	Botrytis cinerea	53.50	5.00e-98	350.00
IUUC-Bdi-014257	Brachypodium distachyon	64.89	4.00e-108	384.00
IUUC-Bol-016310	Brassica oleracea	64.77	4.00e-105	374.00
IUUC-Bra-017438	Brassica rapa	65.80	1.00e-105	375.00
IUUC-Cel-018157	Caenorhabditis elegans	62.12	4.00e-100	357.00
IUUC-Cja-019282	Callithrix jacchus	71.99	4.00e-160	557.00
IUUC-Cfa-020162	Canis familiaris	73.85	1.00e-164	572.00
IUUC-Cpo-021764	Cavia porcellus	67.57	8.00e-155	539.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	67.27	7.00e-110	389.00
IUUC-Csa-023694	Chlorocebus sabaeus	70.23	8.00e-155	539.00
IUUC-Cho-024350	Choloepus hoffmanni	88.14	4.00e-102	363.00
IUUC-Cin-025542	Ciona intestinalis	73.83	2.00e-117	414.00
IUUC-Csv-025873	Ciona savignyi	71.38	7.00e-119	419.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	48.03	1.00e-84	305.00
IUUC-Cne-026928	Cryptococcus neoformans	62.26	2.00e-97	348.00
IUUC-Cme-027336	Cyanidioschyzon merolae	72.31	7.00e-119	420.00
IUUC-Dre-028198	Danio rerio	60.32	1.00e-131	462.00
IUUC-Dno-029928	Dasypus novemcinctus	72.54	4.00e-154	537.00
IUUC-Dor-030238	Dipodomys ordii	64.95	5.00e-142	496.00
IUUC-Dse-031266	Dothistroma septosporum	61.22	5.00e-93	333.00
IUUC-Dme-032007	Drosophila melanogaster	62.16	5.00e-100	357.00
IUUC-Ete-032911	Echinops telfairi	56.56	6.00e-109	387.00
IUUC-Eca-033749	Equus caballus	75.60	2.00e-166	578.00
IUUC-Eeu-035170	Erinaceus europaeus	71.43	4.00e-157	547.00
IUUC-Fca-035498	Felis catus	75.61	4.00e-166	577.00
IUUC-Fal-037397	Ficedula albicollis	72.82	1.00e-162	565.00
IUUC-Fox-037747	Fusarium oxysporum	52.29	1.00e-94	339.00
IUUC-Fso-038429	Fusarium solani	55.59	9.00e-91	326.00
IUUC-Gmo-039378	Gadus morhua	60.31	3.00e-128	451.00
IUUC-Ggr-039939	Gaeumannomyces graminis	62.74	7.00e-97	347.00
IUUC-Gga-040187	Gallus gallus	73.65	3.00e-169	587.00
IUUC-Gac-042223	Gasterosteus aculeatus	61.07	1.00e-133	469.00
IUUC-Gma-042870	Glycine max	63.60	5.00e-100	357.00
IUUC-Ggo-045617	Gorilla gorilla	72.04	9.00e-163	565.00
IUUC-Hsa-046968	Homo sapiens	72.04	2.00e-162	565.00
IUUC-Hvu-047072	Hordeum vulgare	57.14	5.00e-82	296.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	62.77	9.00e-128	449.00
IUUC-Kpa-049093	Komagataella pastoris	57.25	4.00e-79	287.00
IUUC-Lch-050346	Latimeria chalumnae	69.57	2.00e-152	531.00
IUUC-Lpe-051466	Leersia perrieri	69.35	2.00e-107	381.00
IUUC-Lma-053006	Leptosphaeria maculans	59.70	2.00e-90	325.00
IUUC-Laf-053422	Loxodonta africana	72.02	1.00e-160	558.00
IUUC-Mcc-055245	Macaca mulatta	73.26	2.00e-154	538.00
IUUC-Mor-056952	Magnaporthe oryzae	61.60	1.00e-93	336.00
IUUC-Mpo-057605	Magnaporthe poae	61.25	2.00e-97	348.00
IUUC-Mtr-057726	Medicago truncatula	67.18	3.00e-106	377.00
IUUC-Mla-059174	Melampsora laricipopulina	64.62	7.00e-102	363.00
IUUC-Mga-059562	Meleagris gallopavo	63.41	4.00e-130	457.00
IUUC-Mvi-060305	Microbotryum violaceum	62.36	8.00e-95	340.00
IUUC-Mmr-061588	Microcebus murinus	71.50	4.00e-163	566.00
IUUC-Mdo-061914	Monodelphis domestica	76.55	4.00e-170	590.00
IUUC-Mmu-063288	Mus musculus	75.14	6.00e-156	543.00
IUUC-Mac-064969	Musa acuminata	66.31	4.00e-109	387.00
IUUC-Mpu-066855	Mustela putorius furo	75.20	6.00e-165	573.00
IUUC-Mlu-068046	Myotis lucifugus	72.28	2.00e-162	565.00
IUUC-Nfi-068527	Neosartorya fischeri	58.21	4.00e-88	318.00
IUUC-Ncr-068678	Neurospora crassa	62.12	2.00e-94	338.00
IUUC-Nle-069848	Nomascus leucogenys	75.40	3.00e-162	564.00
IUUC-Opr-070589	Ochotona princeps	70.44	8.00e-153	532.00
IUUC-Ont-071733	Oreochromis niloticus	63.00	2.00e-128	451.00
IUUC-Oan-073399	Ornithorhynchus anatinus	88.11	6.00e-151	526.00
IUUC-Ocu-074063	Oryctolagus cuniculus	72.63	1.00e-162	565.00
IUUC-Oba-075264	Oryza barthii	68.97	2.00e-106	377.00
IUUC-Obr-076048	Oryza brachyantha	68.06	4.00e-106	377.00
IUUC-Ogl-077637	Oryza glaberrima	68.97	3.00e-106	377.00
IUUC-Ogu-078830	Oryza glumaepatula	68.97	1.00e-106	378.00
IUUC-Oin-079150	Oryza indica	68.97	1.00e-106	379.00
IUUC-Olo-080398	Oryza longistaminata	54.98	1.00e-84	305.00
IUUC-Ome-081544	Oryza meridionalis	58.17	7.00e-92	329.00
IUUC-Oni-082250	Oryza nivara	68.97	1.00e-106	379.00
IUUC-Opu-083638	Oryza punctata	65.25	9.00e-107	379.00
IUUC-Oru-084981	Oryza rufipogon	68.97	9.00e-107	379.00
IUUC-Osa-085961	Oryza sativa	68.97	9.00e-107	379.00
IUUC-Olu-087880	Ostreococcus lucimarinus	70.93	6.00e-112	396.00
IUUC-Oga-088891	Otolemur garnettii	76.02	7.00e-165	573.00
IUUC-Oar-090021	Ovis aries	73.18	2.00e-158	551.00
IUUC-Ptr-091458	Pan troglodytes	72.29	1.00e-162	565.00
IUUC-Pan-092546	Papio anubis	70.33	9.00e-155	539.00
IUUC-Pma-094298	Petromyzon marinus	81.47	2.00e-124	437.00
IUUC-Pno-094847	Phaeosphaeria nodorum	60.46	2.00e-90	325.00
IUUC-Ppa-095855	Physcomitrella patens	65.07	4.00e-109	387.00
IUUC-Pfo-096428	Poecilia formosa	62.24	4.00e-128	451.00
IUUC-Pab-098696	Pongo abelii	71.54	2.00e-160	558.00
IUUC-Pop-099405	Populus trichocarpa	63.12	6.00e-107	379.00
IUUC-Pca-100740	Procavia capensis	70.73	4.00e-158	550.00
IUUC-Ppe-101854	Prunus persica	64.54	1.00e-109	389.00
IUUC-Pva-103212	Pteropus vampyrus	72.99	5.00e-162	563.00
IUUC-Pgr-103474	Puccinia graminis	64.50	2.00e-100	359.00
IUUC-Ptt-103933	Puccinia triticina	50.00	1.00e-63	236.00
IUUC-Pte-104089	Pyrenophora teres	60.08	7.00e-91	327.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	60.08	6.00e-91	327.00
IUUC-Rno-105057	Rattus norvegicus	74.93	4.00e-155	540.00
IUUC-Sha-107137	Sarcophilus harrisii	76.59	5.00e-172	596.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	57.09	8.00e-101	359.00
IUUC-Spo-108078	Schizosaccharomyces pombe	52.27	2.00e-101	362.00
IUUC-Smo-109288	Selaginella moellendorffii	67.18	4.00e-107	380.00
IUUC-Sit-110246	Setaria italica	64.89	4.00e-107	380.00
IUUC-Sly-111379	Solanum lycopersicum	66.91	9.00e-109	385.00
IUUC-Stu-112777	Solanum tuberosum	68.32	2.00e-107	381.00
IUUC-Sbi-114325	Sorghum bicolor	64.89	5.00e-107	380.00
IUUC-Sre-115203	Sporisorium reilianum	50.27	5.00e-84	304.00
IUUC-Ssc-115361	Sus scrofa	71.79	5.00e-166	577.00
IUUC-Tgu-116967	Taeniopygia guttata	75.95	2.00e-158	551.00
IUUC-Tru-117570	Takifugu rubripes	63.52	7.00e-137	479.00
IUUC-Tsy-119280	Tarsius syrichta	79.81	8.00e-103	366.00
IUUC-Tni-120721	Tetraodon nigroviridis	62.77	6.00e-134	469.00
IUUC-Tca-121494	Theobroma cacao	67.42	3.00e-106	377.00
IUUC-Tre-121869	Trichoderma reesei	54.95	2.00e-96	345.00
IUUC-Tvi-122510	Trichoderma virens	62.88	9.00e-95	340.00
IUUC-Tae-123071	Triticum aestivum	64.54	1.00e-106	378.00
IUUC-Tur-126240	Triticum urartu	64.18	9.00e-106	375.00
IUUC-Tme-126921	Tuber melanosporum	62.69	3.00e-97	348.00
IUUC-Tbe-127872	Tupaia belangeri	66.67	7.00e-147	513.00
IUUC-Ttr-129134	Tursiops truncatus	72.87	2.00e-159	555.00
IUUC-Uma-129412	Ustilago maydis	59.85	1.00e-79	290.00
IUUC-Vda-130003	Verticillium dahliae	52.76	8.00e-94	336.00
IUUC-Vvi-131272	Vitis vinifera	64.18	5.00e-108	383.00
IUUC-Xtr-132019	Xenopus tropicalis	68.07	1.00e-153	535.00
IUUC-Xma-134203	Xiphophorus maculatus	63.99	2.00e-136	478.00
IUUC-Yli-134503	Yarrowia lipolytica	48.06	7.00e-89	320.00
IUUC-Zma-135232	Zea mays	67.53	4.00e-107	380.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence