iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068439

Ensembl Protein ID

CADNFIAP00001128

UniProt Accession

A1D4G0; A1D4G0_NEOFI

Genbank Protein ID

EAW23303.1

Protein Name

Ubiquitin-protein ligase (Hul4), putative

Genbank Nucleotide ID

DS027688

Gene Name

NFIA_020110

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00001167	CADNFIAT00001167	CADNFIAP00001128

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.40e-75	252.2	804	1148

Active Site

Position(s)	Description	Evidence
1117	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
           ++++kk l++efvgEeg+d+gG+ +e++ ll++e+++p  glfly+e+++ + + np  +    e  + F ++G+llg+a++++ +ld+ l
   Q: 804  QEEIKKGLRIEFVGEEGVDAGGLRKEWFLLLVREIFDPHHGLFLYDEDSQFC-YFNPYCF----ESSEQFFLVGVLLGLAIYNSTILDIAL 889
           67899****************************************9976655.6799888....5678888******************** PP
   S: 93   sksfyklllgk................klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
           +++ +k+ll                  +++l+dl+e  p l+k l  ++e  + d+ ++ ++  f ++ + +ge+ ++ L+pgGe+ pVtn
   Q: 890  PPFAFKKLLAAapqtsgpqpssgrsnyRCTLDDLAEYRPALAKGLRALLEF-DGDVADT-FCYDFVAHVDRYGEAVAVPLCPGGETRPVTN 978
           ********88877777777777777667*********************99.7899997.******************************* PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketky...kggytedspaiqwFwevle 254
           +N++e+v+l+v+y l + +++q+e f++Gf +v+  + lslF++ee+ell+ G+ e +dv +l++ ++y    +   e+ p+++wFwe++e
   Q: 979  ANRREFVDLYVHYMLDTAVTRQFEPFKRGFFTVCGGNALSLFRPEEIELLVRGSdEALDVASLRAVATYdnwSHPRPENIPVVRWFWEFFE 1069
           ******************************************************999**********9944445555677888******** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           + + + ++++L F+Tgs+r+P+ G  +l  rl ++ +  + +r+P + TCfn+L L +Y++ e l+++L  A+ +++gF+l
   Q: 1070 NTDPQAQRKILSFITGSDRIPAMGATSLTIRLACLGD--DASRYPIARTCFNTLGLYRYPTRERLERMLWEAVGNSEGFGL 1148
           *****************************99999999..779*************************************98 PP

Organism

Neosartorya fischeri

Protein Sequence
(Fasta)

MPSRSAYNQP HPPTLNSSTV YPNAALLSSS AERSAQRHIQ HDVPILPTMT GNPATSPPLH 60
RGHSRSISHP FPSAFGGKKR NPNPGFLDSD SDDDDVEVTH LPDVLSSSPR KGSSRPLPGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGTCGC GGTCCGCGTA TAACCAGCCT CATCCTCCGA CTCTGAACTC CTCAACCGTC 60
TATCCGAACG CCGCCCTTCT CTCTTCTTCA GCAGAGAGGA GTGCACAACG CCACATCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

nfi:NFIA_020110

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	34.58	4.00e-96	343.00
IUUC-Atr-003144	Amborella trichopoda	38.03	4.00e-83	300.00
IUUC-Apl-003589	Anas platyrhynchos	33.17	3.00e-87	314.00
IUUC-Aca-004350	Anolis carolinensis	39.51	3.00e-91	327.00
IUUC-Ago-007908	Ashbya gossypii	32.89	1.00e-101	362.00
IUUC-Acl-008288	Aspergillus clavatus	75.31	0.00e+00	1718.00
IUUC-Afl-008402	Aspergillus flavus	78.53	0.00e+00	1088.00
IUUC-Afu-008762	Aspergillus fumigatus	92.09	0.00e+00	2181.00
IUUC-Ani-009176	Aspergillus nidulans	73.57	0.00e+00	919.00
IUUC-Ang-009791	Aspergillus niger	64.95	0.00e+00	1305.00
IUUC-Aor-009921	Aspergillus oryzae	79.04	0.00e+00	993.00
IUUC-Ate-010295	Aspergillus terreus	65.70	0.00e+00	1411.00
IUUC-Ame-011166	Astyanax mexicanus	37.47	2.00e-81	295.00
IUUC-Bgr-011981	Blumeria graminis	53.44	0.00e+00	922.00
IUUC-Bta-012945	Bos taurus	39.51	4.00e-93	334.00
IUUC-Bci-013697	Botrytis cinerea	53.90	0.00e+00	871.00
IUUC-Cel-018150	Caenorhabditis elegans	30.98	5.00e-52	197.00
IUUC-Cja-019263	Callithrix jacchus	38.63	4.00e-90	324.00
IUUC-Cfa-020486	Canis familiaris	34.15	1.00e-95	342.00
IUUC-Cpo-021755	Cavia porcellus	34.86	7.00e-97	346.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	41.89	5.00e-59	219.00
IUUC-Csa-023814	Chlorocebus sabaeus	38.67	1.00e-80	292.00
IUUC-Cho-025059	Choloepus hoffmanni	34.73	9.00e-68	249.00
IUUC-Cin-025643	Ciona intestinalis	31.48	2.00e-66	245.00
IUUC-Csv-026282	Ciona savignyi	36.11	2.00e-60	226.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	51.70	0.00e+00	840.00
IUUC-Cme-027151	Cyanidioschyzon merolae	36.34	5.00e-75	274.00
IUUC-Dre-028551	Danio rerio	39.02	6.00e-91	327.00
IUUC-Dno-029497	Dasypus novemcinctus	39.29	7.00e-93	333.00
IUUC-Dor-030158	Dipodomys ordii	33.57	7.00e-67	247.00
IUUC-Dse-031239	Dothistroma septosporum	50.77	0.00e+00	862.00
IUUC-Dme-032103	Drosophila melanogaster	34.27	2.00e-67	249.00
IUUC-Ete-032902	Echinops telfairi	32.02	1.00e-86	312.00
IUUC-Eca-033678	Equus caballus	34.81	3.00e-97	348.00
IUUC-Eeu-035109	Erinaceus europaeus	36.14	8.00e-70	256.00
IUUC-Fca-035590	Felis catus	34.98	2.00e-98	351.00
IUUC-Fal-036747	Ficedula albicollis	37.69	3.00e-79	288.00
IUUC-Fox-037941	Fusarium oxysporum	48.60	0.00e+00	874.00
IUUC-Fso-038388	Fusarium solani	51.59	0.00e+00	857.00
IUUC-Gmo-039553	Gadus morhua	38.36	4.00e-79	287.00
IUUC-Ggr-040110	Gaeumannomyces graminis	50.06	0.00e+00	817.00
IUUC-Gga-040406	Gallus gallus	33.50	5.00e-92	330.00
IUUC-Gac-042141	Gasterosteus aculeatus	32.84	5.00e-86	310.00
IUUC-Ggo-045504	Gorilla gorilla	38.63	8.00e-91	326.00
IUUC-Hsa-045786	Homo sapiens	38.63	1.00e-90	326.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	38.24	5.00e-75	274.00
IUUC-Kpa-049152	Komagataella pastoris	35.29	4.00e-98	350.00
IUUC-Lch-049824	Latimeria chalumnae	39.28	3.00e-79	288.00
IUUC-Loc-052173	Lepisosteus oculatus	34.48	2.00e-98	351.00
IUUC-Laf-054017	Loxodonta africana	39.07	3.00e-92	331.00
IUUC-Mcc-055713	Macaca mulatta	38.63	4.00e-90	323.00
IUUC-Meu-056061	Macropus eugenii	37.03	2.00e-75	275.00
IUUC-Mor-057045	Magnaporthe oryzae	46.02	0.00e+00	891.00
IUUC-Mla-059187	Melampsora laricipopulina	42.00	2.00e-93	334.00
IUUC-Mga-059884	Meleagris gallopavo	39.01	6.00e-84	303.00
IUUC-Mmr-061344	Microcebus murinus	34.32	9.00e-97	346.00
IUUC-Mdo-062653	Monodelphis domestica	40.09	1.00e-92	332.00
IUUC-Mmu-063775	Mus musculus	39.87	5.00e-94	337.00
IUUC-Mpu-066069	Mustela putorius furo	34.65	4.00e-97	347.00
IUUC-Mlu-067925	Myotis lucifugus	39.74	4.00e-94	337.00
IUUC-Ncr-068903	Neurospora crassa	50.50	0.00e+00	815.00
IUUC-Nle-070046	Nomascus leucogenys	33.77	3.00e-93	334.00
IUUC-Opr-070891	Ochotona princeps	34.43	3.00e-57	215.00
IUUC-Ont-072126	Oreochromis niloticus	34.15	6.00e-94	336.00
IUUC-Oan-072933	Ornithorhynchus anatinus	38.68	1.00e-89	322.00
IUUC-Ocu-073800	Oryctolagus cuniculus	38.85	2.00e-90	324.00
IUUC-Ola-086988	Oryzias latipes	33.77	2.00e-90	325.00
IUUC-Oga-088117	Otolemur garnettii	39.29	2.00e-91	327.00
IUUC-Oar-089371	Ovis aries	39.51	6.00e-93	333.00
IUUC-Ptr-090551	Pan troglodytes	38.63	1.00e-90	326.00
IUUC-Pan-092067	Papio anubis	38.63	3.00e-90	324.00
IUUC-Psi-092963	Pelodiscus sinensis	39.29	3.00e-90	324.00
IUUC-Pma-094643	Petromyzon marinus	32.67	4.00e-80	291.00
IUUC-Ppa-095354	Physcomitrella patens	38.02	4.00e-84	304.00
IUUC-Pfo-096562	Poecilia formosa	33.50	1.00e-91	329.00
IUUC-Pab-098680	Pongo abelii	38.41	3.00e-90	324.00
IUUC-Pca-100869	Procavia capensis	36.36	2.00e-76	278.00
IUUC-Pva-102219	Pteropus vampyrus	37.26	2.00e-74	271.00
IUUC-Pgr-103315	Puccinia graminis	41.48	1.00e-101	362.00
IUUC-Ptt-103736	Puccinia triticina	41.53	3.00e-100	358.00
IUUC-Rno-105270	Rattus norvegicus	39.96	9.00e-95	339.00
IUUC-Sce-106306	Saccharomyces cerevisiae	32.33	2.00e-85	308.00
IUUC-Sha-106819	Sarcophilus harrisii	35.41	3.00e-99	354.00
IUUC-Sja-107974	Schizosaccharomyces japonicus	35.24	9.00e-60	223.00
IUUC-Spo-108271	Schizosaccharomyces pombe	35.57	3.00e-110	390.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	54.27	0.00e+00	901.00
IUUC-Smo-108858	Selaginella moellendorffii	39.48	6.00e-85	306.00
IUUC-Sar-113134	Sorex araneus	35.56	3.00e-76	278.00
IUUC-Ssc-115441	Sus scrofa	39.43	9.00e-93	332.00
IUUC-Tgu-117166	Taeniopygia guttata	33.66	7.00e-88	316.00
IUUC-Tru-118368	Takifugu rubripes	36.59	2.00e-78	285.00
IUUC-Tsy-118898	Tarsius syrichta	35.37	1.00e-73	269.00
IUUC-Tni-120143	Tetraodon nigroviridis	36.81	1.00e-78	286.00
IUUC-Tre-122108	Trichoderma reesei	51.17	0.00e+00	830.00
IUUC-Tvi-122644	Trichoderma virens	50.50	0.00e+00	827.00
IUUC-Tme-127004	Tuber melanosporum	48.64	0.00e+00	801.00
IUUC-Tbe-127640	Tupaia belangeri	36.56	7.00e-64	237.00
IUUC-Ttr-128352	Tursiops truncatus	36.87	6.00e-83	300.00
IUUC-Vda-129969	Verticillium dahliae	49.83	0.00e+00	819.00
IUUC-Vpa-130448	Vicugna pacos	34.27	2.00e-67	249.00
IUUC-Xtr-132594	Xenopus tropicalis	38.07	4.00e-80	291.00
IUUC-Xma-134157	Xiphophorus maculatus	33.45	1.00e-82	299.00
IUUC-Yli-134470	Yarrowia lipolytica	34.60	3.00e-106	378.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence