iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045410

UUCD1 version

UUC-GoG-00930

Ensembl Protein ID

ENSGGOP00000026394.1

UniProt Accession

G3SE64; G3SE64_GORGO

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000026848.1	ENSGGOT00000024636.1	ENSGGOP00000026394.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-53	176.8	319	357
UBD/Beta-Prp	4.60e-84	282.5	87	393

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH ++v+++ f s+ ++++s++dD+t++vWD+++ ++ k
   Q: 319  GHGNWVRGILFsSGgKFILSCADDKTLHVWDYKSKRCMK 357
           8**********9888******************999987 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           tl+gh+ s+it v f+p  s+++++s+d+tikvwd++tg++ r+l+gh++ v++++f+++gk+l+++s  +tik+wd+++++c++t++ 
   Q: 87   TLSGHR-SPITRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKFLASCSAAMTIKLWDFQDFECIRTMN- 173
           555555.59999****************************************************************************. PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h+++v s+ +++ gd++vs+s+d+ti++w+++tg+c++ +++g++++v +v+ ++dg l++s+s+D+tvr+W ++t+++  +l++ h++
   Q: 174  HDHNVSSVVIMAGGDHIVSASRDKTIKMWEVQTGYCVK-MFTGQREWVHMVQPNQDGTLIASCSNDQTVRVWVIATMQCKAELRE-HEH 260
           ************99************************.*********************************************9.*** PP
   S: 182  svyslsfdsng....................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
            v+++s+ +++                    ++l+sgs+d+t+k+wd++tg c++tl gh ++v+ + fs+ +++++s+++D+++ +Wd
   Q: 261  VVECISWAPESsyssiseatdsetkksgksgPFLLSGSRDKTIKMWDVSTGMCLMTLVGHGNWVRGILFSSGGKFILSCADDKTLHVWD 349
           ******999999999************************************************************************** PP
   S: 251  lrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklk 295
           ++s+ ++ktl+  ++ v+s ++ + + +++v+gs  ++v++w+++
   Q: 350  YKSKRCMKTLNAYEHFVTSLDF-HKTAPYVVTGSVAQTVKVWECR 393
           **********************.99*****************985 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

NQAKADYLRS NGYEEAYSVF KEAELDMNEE LKAGVLGEKW TSVIRLQKKF MELESMLNEA 60
KEEFTSGGPL GQKQDPKEWV FLPEKYTLSG HRSPITRVIF HPVFSVMVSA SEDATIKVWD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCAAGCTA AAGCAGATTA TCTTCGTTCA AATGGCTATG AAGAGGCATA TTCAGTTTTT 60
TAAAAGGAAG CTGAATTAGA TATGAATGAA GAATTAAAGT AGGCTGGTGT TTTGGGGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR017252--Dynein_regulator_LIS1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000235--C:astral microtubule
GO:1904115--C:axon cytoplasm
GO:0005938--C:cell cortex
GO:0031252--C:cell leading edge
GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0000776--C:kinetochore
GO:0005875--C:microtubule associated complex
GO:0031514--C:motile cilium
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0032420--C:stereocilium
GO:0001675--P:acrosome assembly
GO:0030036--P:actin cytoskeleton organization
GO:0008344--P:adult locomotory behavior
GO:0001667--P:ameboidal-type cell migration
GO:0060117--P:auditory receptor cell development
GO:0048854--P:brain morphogenesis
GO:0051301--P:cell division
GO:0007268--P:chemical synaptic transmission
GO:0090102--P:cochlea development
GO:0021540--P:corpus callosum morphogenesis
GO:0043622--P:cortical microtubule organization
GO:0000132--P:establishment of mitotic spindle orientation
GO:0042249--P:establishment of planar polarity of embryonic epithelium
GO:0021766--P:hippocampus development
GO:0021819--P:layer formation in cerebral cortex
GO:0007611--P:learning or memory
GO:0051661--P:maintenance of centrosome location
GO:0090176--P:microtubule cytoskeleton organization involved in establishment of planar polarity
GO:0031023--P:microtubule organizing center organization
GO:0007067--P:mitotic nuclear division
GO:0046329--P:negative regulation of JNK cascade
GO:0007405--P:neuroblast proliferation
GO:0050885--P:neuromuscular process controlling balance
GO:0001764--P:neuron migration
GO:0051081--P:nuclear envelope disassembly
GO:0036035--P:osteoclast development
GO:0001961--P:positive regulation of cytokine-mediated signaling pathway
GO:0061003--P:positive regulation of dendritic spine morphogenesis
GO:0040019--P:positive regulation of embryonic development
GO:0009306--P:protein secretion
GO:0043087--P:regulation of GTPase activity
GO:0070507--P:regulation of microtubule cytoskeleton organization
GO:0008090--P:retrograde axonal transport
GO:0019226--P:transmission of nerve impulse
GO:0047496--P:vesicle transport along microtubule

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001589	Ailuropoda melanoleuca	89.22	0.00e+00	725.00
IUUC-Apl-004024	Anas platyrhynchos	87.97	0.00e+00	719.00
IUUC-Aca-004564	Anolis carolinensis	87.72	0.00e+00	714.00
IUUC-Acl-008360	Aspergillus clavatus	43.19	1.00e-85	310.00
IUUC-Afl-008502	Aspergillus flavus	44.54	4.00e-81	295.00
IUUC-Afu-008848	Aspergillus fumigatus	43.70	3.00e-86	311.00
IUUC-Ani-009173	Aspergillus nidulans	42.24	1.00e-75	276.00
IUUC-Ang-009873	Aspergillus niger	41.95	1.00e-80	293.00
IUUC-Aor-009973	Aspergillus oryzae	43.19	2.00e-76	279.00
IUUC-Ate-010523	Aspergillus terreus	41.43	8.00e-74	270.00
IUUC-Ame-010969	Astyanax mexicanus	84.21	0.00e+00	692.00
IUUC-Bgr-011972	Blumeria graminis	43.36	7.00e-87	314.00
IUUC-Bta-013106	Bos taurus	89.22	0.00e+00	726.00
IUUC-Bci-013615	Botrytis cinerea	41.10	9.00e-81	293.00
IUUC-Cel-018459	Caenorhabditis elegans	51.76	5.00e-124	437.00
IUUC-Cja-018755	Callithrix jacchus	89.22	0.00e+00	725.00
IUUC-Cfa-020749	Canis familiaris	89.22	0.00e+00	726.00
IUUC-Cpo-022371	Cavia porcellus	89.22	0.00e+00	726.00
IUUC-Csa-023524	Chlorocebus sabaeus	90.14	0.00e+00	644.00
IUUC-Cho-024764	Choloepus hoffmanni	78.98	2.00e-169	588.00
IUUC-Cin-025753	Ciona intestinalis	63.25	9.00e-150	523.00
IUUC-Csv-025817	Ciona savignyi	61.81	3.00e-153	534.00
IUUC-Cgl-026529	Colletotrichum gloeosporioides	43.67	1.00e-78	286.00
IUUC-Cne-027087	Cryptococcus neoformans	44.68	8.00e-95	340.00
IUUC-Dre-028314	Danio rerio	82.71	0.00e+00	687.00
IUUC-Dno-029050	Dasypus novemcinctus	88.97	0.00e+00	725.00
IUUC-Dor-030222	Dipodomys ordii	80.95	0.00e+00	645.00
IUUC-Dse-031164	Dothistroma septosporum	40.71	7.00e-82	297.00
IUUC-Dme-031745	Drosophila melanogaster	62.81	1.00e-141	496.00
IUUC-Eca-034288	Equus caballus	88.72	0.00e+00	720.00
IUUC-Eeu-034984	Erinaceus europaeus	80.70	0.00e+00	641.00
IUUC-Fca-036498	Felis catus	89.22	0.00e+00	726.00
IUUC-Fal-036920	Ficedula albicollis	87.97	0.00e+00	719.00
IUUC-Fox-037996	Fusarium oxysporum	42.08	5.00e-85	308.00
IUUC-Fso-038160	Fusarium solani	41.19	8.00e-81	294.00
IUUC-Gmo-038983	Gadus morhua	83.71	0.00e+00	684.00
IUUC-Ggr-040051	Gaeumannomyces graminis	41.86	7.00e-81	294.00
IUUC-Gga-040623	Gallus gallus	87.97	0.00e+00	719.00
IUUC-Gac-041613	Gasterosteus aculeatus	82.96	0.00e+00	682.00
IUUC-Hsa-046358	Homo sapiens	88.97	0.00e+00	724.00
IUUC-Itr-047890	Ictidomys tridecemlineatus	89.22	0.00e+00	726.00
IUUC-Lch-049936	Latimeria chalumnae	85.96	0.00e+00	702.00
IUUC-Loc-052476	Lepisosteus oculatus	85.21	0.00e+00	695.00
IUUC-Lma-053170	Leptosphaeria maculans	45.75	4.00e-85	308.00
IUUC-Laf-053713	Loxodonta africana	88.97	0.00e+00	724.00
IUUC-Mcc-054628	Macaca mulatta	88.72	0.00e+00	723.00
IUUC-Mor-056962	Magnaporthe oryzae	42.63	1.00e-80	293.00
IUUC-Mpo-057583	Magnaporthe poae	41.54	7.00e-77	281.00
IUUC-Mla-058819	Melampsora laricipopulina	45.08	6.00e-102	364.00
IUUC-Mga-059945	Meleagris gallopavo	87.72	0.00e+00	718.00
IUUC-Mvi-060403	Microbotryum violaceum	45.22	2.00e-105	376.00
IUUC-Mmr-061289	Microcebus murinus	89.22	0.00e+00	724.00
IUUC-Mdo-061912	Monodelphis domestica	88.47	0.00e+00	719.00
IUUC-Mmu-063253	Mus musculus	89.22	0.00e+00	726.00
IUUC-Mpu-066638	Mustela putorius furo	89.22	0.00e+00	726.00
IUUC-Mlu-067267	Myotis lucifugus	88.97	0.00e+00	723.00
IUUC-Nfi-068571	Neosartorya fischeri	42.78	5.00e-79	288.00
IUUC-Ncr-068895	Neurospora crassa	46.13	7.00e-88	317.00
IUUC-Nle-069087	Nomascus leucogenys	88.58	1.00e-167	582.00
IUUC-Opr-070579	Ochotona princeps	88.97	0.00e+00	725.00
IUUC-Ont-072432	Oreochromis niloticus	84.21	0.00e+00	692.00
IUUC-Oan-073072	Ornithorhynchus anatinus	89.22	0.00e+00	726.00
IUUC-Ocu-074180	Oryctolagus cuniculus	88.97	0.00e+00	725.00
IUUC-Ola-086772	Oryzias latipes	83.71	0.00e+00	683.00
IUUC-Oga-088219	Otolemur garnettii	89.22	0.00e+00	726.00
IUUC-Oar-090394	Ovis aries	89.22	0.00e+00	726.00
IUUC-Ptr-091517	Pan troglodytes	89.22	0.00e+00	726.00
IUUC-Pan-092421	Papio anubis	88.72	0.00e+00	723.00
IUUC-Psi-093370	Pelodiscus sinensis	88.22	0.00e+00	721.00
IUUC-Pma-094319	Petromyzon marinus	80.23	4.00e-164	570.00
IUUC-Pno-094815	Phaeosphaeria nodorum	45.38	4.00e-86	311.00
IUUC-Pfo-097089	Poecilia formosa	83.21	0.00e+00	684.00
IUUC-Pab-098421	Pongo abelii	89.22	0.00e+00	726.00
IUUC-Pca-100120	Procavia capensis	64.91	1.00e-136	479.00
IUUC-Pva-102960	Pteropus vampyrus	88.97	0.00e+00	721.00
IUUC-Pgr-103538	Puccinia graminis	44.09	1.00e-100	360.00
IUUC-Ptt-103990	Puccinia triticina	39.00	7.00e-33	135.00
IUUC-Pte-104261	Pyrenophora teres	45.31	5.00e-85	308.00
IUUC-Pyt-104780	Pyrenophora triticirepentis	45.58	2.00e-85	309.00
IUUC-Rno-105123	Rattus norvegicus	89.22	0.00e+00	726.00
IUUC-Sha-107010	Sarcophilus harrisii	88.47	0.00e+00	719.00
IUUC-Sja-107899	Schizosaccharomyces japonicus	31.70	3.00e-52	199.00
IUUC-Ssl-108571	Sclerotinia sclerotiorum	41.35	4.00e-81	295.00
IUUC-Sar-113309	Sorex araneus	88.47	0.00e+00	716.00
IUUC-Sre-115003	Sporisorium reilianum	49.21	4.00e-104	371.00
IUUC-Ssc-116148	Sus scrofa	89.22	0.00e+00	726.00
IUUC-Tgu-117299	Taeniopygia guttata	87.72	0.00e+00	716.00
IUUC-Tru-117721	Takifugu rubripes	82.46	0.00e+00	677.00
IUUC-Tsy-119493	Tarsius syrichta	87.72	0.00e+00	710.00
IUUC-Tni-120355	Tetraodon nigroviridis	82.71	0.00e+00	659.00
IUUC-Tre-121977	Trichoderma reesei	38.65	3.00e-80	292.00
IUUC-Tvi-122661	Trichoderma virens	42.64	1.00e-79	290.00
IUUC-Tme-127031	Tuber melanosporum	44.53	2.00e-83	303.00
IUUC-Ttr-128929	Tursiops truncatus	88.97	0.00e+00	723.00
IUUC-Uma-129347	Ustilago maydis	44.24	7.00e-104	370.00
IUUC-Vda-129837	Verticillium dahliae	41.44	1.00e-81	296.00
IUUC-Vpa-130532	Vicugna pacos	74.40	1.00e-155	542.00
IUUC-Xtr-131985	Xenopus tropicalis	86.72	0.00e+00	713.00
IUUC-Xma-133314	Xiphophorus maculatus	83.71	0.00e+00	687.00
IUUC-Yli-134403	Yarrowia lipolytica	36.59	8.00e-62	231.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence