iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096633

Ensembl Protein ID

ENSPFOP00000014200.1

UniProt Accession

A0A087Y847; A0A087Y847_POEFO

Genbank Protein ID

ENSPFOP00000014200

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AYCK01012130

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000014186.1	ENSPFOT00000014220.1	ENSPFOP00000014200.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-08	35.7	222	268

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C++ + +e  ++ C++  C+ ewfH+ C++l+    +p+ + w+CpkCr
   Q: 222  TYC-LCEQVSYGE--MIGCDNdqCHiEWFHFSCVGLT---YKPKGK-WYCPKCR 268
           69*.*******99..*****99***************...888886.******8 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

ALLCIAETML GHHYQNADKS QQLVNYVEDY LECVESLPLD IQRNVSLLRE IDAKYQEVLK 60
EVDEVFEKYK GEQDSAQRKR LQIQLQRALI LSQELGDEKI HVVTQMTELV ENRSRQMDSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTCCAGCT CTAAAGCCCC GCCTTTAGTG ACGACAGCAG TAAGAGGAAG CTGTGCAATA 60
CCATAAAAGG AAAATTTCTG CGCATGCGTA GTTGTGTGAG TTTTGTTTGA AGTGAATTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	66.67	9.00e-78	283.00
IUUC-Apl-003910	Anas platyrhynchos	56.23	5.00e-74	271.00
IUUC-Aca-004990	Anolis carolinensis	66.67	1.00e-83	302.00
IUUC-Ame-011426	Astyanax mexicanus	68.55	1.00e-88	319.00
IUUC-Bta-012721	Bos taurus	65.69	5.00e-77	280.00
IUUC-Cja-018960	Callithrix jacchus	65.93	9.00e-70	256.00
IUUC-Cfa-020869	Canis familiaris	66.67	1.00e-77	283.00
IUUC-Cpo-021414	Cavia porcellus	67.03	4.00e-78	284.00
IUUC-Csa-023304	Chlorocebus sabaeus	66.30	2.00e-70	258.00
IUUC-Cho-024577	Choloepus hoffmanni	53.28	9.00e-56	209.00
IUUC-Dre-028562	Danio rerio	73.94	2.00e-98	351.00
IUUC-Dno-029945	Dasypus novemcinctus	65.57	3.00e-76	278.00
IUUC-Dor-030141	Dipodomys ordii	63.74	2.00e-74	272.00
IUUC-Dse-031323	Dothistroma septosporum	56.06	3.00e-18	87.00
IUUC-Ete-032709	Echinops telfairi	64.96	8.00e-85	306.00
IUUC-Eca-033432	Equus caballus	66.06	4.00e-77	281.00
IUUC-Eeu-035285	Erinaceus europaeus	66.05	2.00e-61	228.00
IUUC-Fca-036467	Felis catus	66.30	4.00e-77	281.00
IUUC-Fal-036838	Ficedula albicollis	56.23	5.00e-74	270.00
IUUC-Gmo-038748	Gadus morhua	77.82	4.00e-112	397.00
IUUC-Gac-041403	Gasterosteus aculeatus	88.26	1.00e-133	468.00
IUUC-Ggo-045481	Gorilla gorilla	52.16	3.00e-56	213.00
IUUC-Hsa-045837	Homo sapiens	66.30	2.00e-70	258.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	66.30	3.00e-77	281.00
IUUC-Lch-049965	Latimeria chalumnae	65.11	2.00e-83	302.00
IUUC-Mcc-055031	Macaca mulatta	52.38	3.00e-56	212.00
IUUC-Meu-056470	Macropus eugenii	68.56	1.00e-84	306.00
IUUC-Mga-059570	Meleagris gallopavo	66.67	1.00e-68	252.00
IUUC-Mmr-061385	Microcebus murinus	65.93	6.00e-70	257.00
IUUC-Mdo-062144	Monodelphis domestica	68.56	2.00e-84	305.00
IUUC-Mmu-063215	Mus musculus	65.57	5.00e-77	280.00
IUUC-Mpu-065749	Mustela putorius furo	65.46	1.00e-68	252.00
IUUC-Nle-069122	Nomascus leucogenys	56.98	4.00e-75	274.00
IUUC-Ont-071524	Oreochromis niloticus	93.73	2.00e-137	481.00
IUUC-Oan-073023	Ornithorhynchus anatinus	56.60	1.00e-73	269.00
IUUC-Ocu-074870	Oryctolagus cuniculus	66.30	3.00e-77	281.00
IUUC-Ola-087400	Oryzias latipes	88.84	4.00e-88	317.00
IUUC-Olu-087851	Ostreococcus lucimarinus	67.31	1.00e-18	86.70
IUUC-Oga-088336	Otolemur garnettii	65.93	5.00e-70	257.00
IUUC-Oar-090136	Ovis aries	65.57	1.00e-76	279.00
IUUC-Ptr-090589	Pan troglodytes	56.60	1.00e-74	273.00
IUUC-Pan-092819	Papio anubis	66.30	2.00e-70	258.00
IUUC-Pab-098346	Pongo abelii	66.30	5.00e-70	257.00
IUUC-Pca-100278	Procavia capensis	66.29	6.00e-82	296.00
IUUC-Pva-103190	Pteropus vampyrus	66.30	2.00e-77	281.00
IUUC-Rno-104940	Rattus norvegicus	64.23	1.00e-76	280.00
IUUC-Sha-107533	Sarcophilus harrisii	68.56	3.00e-84	305.00
IUUC-Sar-113630	Sorex araneus	66.51	4.00e-61	227.00
IUUC-Ssc-115734	Sus scrofa	66.30	3.00e-77	281.00
IUUC-Tgu-116822	Taeniopygia guttata	56.23	4.00e-74	271.00
IUUC-Tru-118168	Takifugu rubripes	84.70	9.00e-113	399.00
IUUC-Tsy-119494	Tarsius syrichta	65.50	8.00e-56	209.00
IUUC-Tni-119663	Tetraodon nigroviridis	83.99	9.00e-114	402.00
IUUC-Tvi-122341	Trichoderma virens	60.34	5.00e-16	77.00
IUUC-Ttr-128442	Tursiops truncatus	65.58	3.00e-61	228.00
IUUC-Vpa-130063	Vicugna pacos	66.06	1.00e-77	283.00
IUUC-Xtr-132348	Xenopus tropicalis	85.00	4.00e-33	135.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence