iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033359

UUCD1 version

UUC-EqC-00518

Ensembl Protein ID

ENSECAP00000019413.1

UniProt Accession

F6YL06; F6YL06_HORSE

Protein Name

Uncharacterized protein

Gene Name

GNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021999.1	ENSECAT00000023439.1	ENSECAP00000019413.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.40e-43	142.5	224	260
UBD/Beta-Prp	3.80e-84	282.5	47	268

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH++++++++f ++ + +++GsdD t++++Dlr +  
   Q: 224  GHESDINAICFfPNgNAFATGSDDATCRLFDLRADQE 260
           8*********99777*****************98865 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   vh++   ++ v+++++ psg++++ G+ d++  +++l+t++     
   Q: 47   TRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRv 135
           5689******************************************************************************9877667 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
              l+gh+g  +c ++ + +n +v++s D+t+ lWd++tg+  +t+tg ht++v sls+ ++ + +vsg++d + klwd+++g c +t+
   Q: 136  srELAGHTGYLSCCRFLD-DNQIVTSSGDTTCALWDIETGQQTTTFTG-HTGDVMSLSLAPDARLFVSGACDASAKLWDVREGMCRQTF 222
           77**************99.78899***********************9.**************************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           +gh++ ++ + f+pn++ +++gs+D + r++dlr ++ l t+++ n
   Q: 223  TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
           *************************************999998844 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSELDQLRQE AEQLKNQIRD ARKACADATL SQITNNIDPV GRIQMRTRRT LRGHLAKIYA 60
MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACAATTTT ACATGTGTTG GAGACCAGAC CAGAAGCACT TCTGAATTAA GGTAATTTTG 60
ATGTAATTGA TCCTTTAAGA AGTTTTTAAA GTACAGAATT TAAATTTCTT CAGGGTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005834--C:heterotrimeric G-protein complex
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0001750--C:photoreceptor outer segment
GO:0003924--F:GTPase activity
GO:0008283--P:cell proliferation
GO:0007200--P:phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0060041--P:retina development in camera-type eye
GO:0050909--P:sensory perception of taste

KEGG

ecb:100061395

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001337	Ailuropoda melanoleuca	99.71	0.00e+00	668.00
IUUC-Apl-003811	Anas platyrhynchos	98.24	0.00e+00	659.00
IUUC-Acl-008154	Aspergillus clavatus	68.55	5.00e-138	484.00
IUUC-Afl-008568	Aspergillus flavus	68.82	6.00e-140	489.00
IUUC-Afu-008789	Aspergillus fumigatus	68.55	5.00e-138	483.00
IUUC-Ani-009213	Aspergillus nidulans	69.12	2.00e-139	488.00
IUUC-Ang-009836	Aspergillus niger	68.82	4.00e-140	490.00
IUUC-Aor-010165	Aspergillus oryzae	68.82	6.00e-140	489.00
IUUC-Ame-011092	Astyanax mexicanus	97.94	0.00e+00	670.00
IUUC-Bta-012709	Bos taurus	99.71	0.00e+00	668.00
IUUC-Cja-019782	Callithrix jacchus	99.71	0.00e+00	668.00
IUUC-Cfa-020111	Canis familiaris	99.71	0.00e+00	668.00
IUUC-Cpo-022494	Cavia porcellus	99.71	0.00e+00	668.00
IUUC-Csa-023672	Chlorocebus sabaeus	99.71	0.00e+00	668.00
IUUC-Cne-026811	Cryptococcus neoformans	67.87	1.00e-138	485.00
IUUC-Dre-028478	Danio rerio	98.53	0.00e+00	694.00
IUUC-Fal-037004	Ficedula albicollis	98.24	0.00e+00	659.00
IUUC-Gmo-039709	Gadus morhua	98.24	0.00e+00	692.00
IUUC-Gga-041163	Gallus gallus	97.85	0.00e+00	630.00
IUUC-Gac-041386	Gasterosteus aculeatus	97.65	0.00e+00	668.00
IUUC-Gma-043322	Glycine max	45.23	7.00e-87	313.00
IUUC-Ggo-045261	Gorilla gorilla	99.38	0.00e+00	629.00
IUUC-Hsa-046450	Homo sapiens	99.71	0.00e+00	668.00
IUUC-Itr-049064	Ictidomys tridecemlineatus	99.71	0.00e+00	668.00
IUUC-Lch-049422	Latimeria chalumnae	97.65	0.00e+00	657.00
IUUC-Loc-052939	Lepisosteus oculatus	98.24	0.00e+00	694.00
IUUC-Lma-052985	Leptosphaeria maculans	67.96	2.00e-136	478.00
IUUC-Laf-054222	Loxodonta africana	99.71	0.00e+00	668.00
IUUC-Mcc-054970	Macaca mulatta	99.71	0.00e+00	668.00
IUUC-Mvi-060482	Microbotryum violaceum	72.29	2.00e-149	521.00
IUUC-Mmr-061302	Microcebus murinus	100.00	0.00e+00	670.00
IUUC-Mdo-062044	Monodelphis domestica	99.12	0.00e+00	664.00
IUUC-Mmu-063323	Mus musculus	99.71	0.00e+00	668.00
IUUC-Mlu-067309	Myotis lucifugus	99.71	0.00e+00	668.00
IUUC-Nfi-068332	Neosartorya fischeri	68.55	2.00e-137	482.00
IUUC-Nle-069791	Nomascus leucogenys	99.71	0.00e+00	668.00
IUUC-Ont-071280	Oreochromis niloticus	98.24	0.00e+00	693.00
IUUC-Oan-072780	Ornithorhynchus anatinus	98.53	0.00e+00	662.00
IUUC-Ocu-073769	Oryctolagus cuniculus	99.71	0.00e+00	668.00
IUUC-Ola-087490	Oryzias latipes	97.24	0.00e+00	639.00
IUUC-Oga-087961	Otolemur garnettii	99.71	0.00e+00	668.00
IUUC-Pan-092079	Papio anubis	99.71	0.00e+00	668.00
IUUC-Psi-093225	Pelodiscus sinensis	98.24	0.00e+00	659.00
IUUC-Pno-095135	Phaeosphaeria nodorum	67.96	3.00e-136	478.00
IUUC-Pfo-097028	Poecilia formosa	97.35	0.00e+00	668.00
IUUC-Pab-098658	Pongo abelii	99.71	0.00e+00	668.00
IUUC-Pca-100313	Procavia capensis	99.12	0.00e+00	657.00
IUUC-Pva-102636	Pteropus vampyrus	99.41	0.00e+00	666.00
IUUC-Pgr-103321	Puccinia graminis	73.19	4.00e-150	523.00
IUUC-Ptt-103728	Puccinia triticina	73.19	4.00e-150	523.00
IUUC-Pte-104053	Pyrenophora teres	66.96	2.00e-136	478.00
IUUC-Pyt-104426	Pyrenophora triticirepentis	62.83	5.00e-124	437.00
IUUC-Rno-105112	Rattus norvegicus	99.71	0.00e+00	668.00
IUUC-Sha-106856	Sarcophilus harrisii	99.12	0.00e+00	664.00
IUUC-Sre-115035	Sporisorium reilianum	69.97	2.00e-140	491.00
IUUC-Tgu-116775	Taeniopygia guttata	98.15	0.00e+00	629.00
IUUC-Tru-117793	Takifugu rubripes	97.94	0.00e+00	671.00
IUUC-Tni-120495	Tetraodon nigroviridis	97.35	0.00e+00	663.00
IUUC-Tme-126886	Tuber melanosporum	70.36	3.00e-136	478.00
IUUC-Uma-129589	Ustilago maydis	70.27	5.00e-141	493.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence