iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026797

Ensembl Protein ID

AAW44468

UniProt Accession

P0CO40; Q55NZ6; Q5KEG2; JHD1_CRYNJ

Genbank Protein ID

AAW44468.1

Protein Name

JmjC domain-containing histone demethylation protein 1; [Histone-H3]-lysine-36 demethylase 1

Genbank Nucleotide ID

AE017347

Gene Name

JHD1; CNG00620

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNG00620	AAW44468	AAW44468

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	37.01	4.00e-54	210.00	IUUC-Dme-032039

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cryptococcus neoformans

Functional Description
(View)

Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.

Protein Sequence
(Fasta)

MSEQVGQREA VDSPQATGVK TPPEPCPLCR ETGPPQPPSI TEEGKTNEDI DFIWVACNKC 60
DEWYHSACLF LGDEKWRGTI PKEIISTVET NFGDEGAWTN WVEWIGKWYC APCLARSTSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCCGCACC CTATATTAAT ACCAACGTCG CATATTACGA AGGATGAGCG AGCAAGTGGG 60
ACAAAGAGAA GCAGTCGATT CTCCTCAAGC TACTGGCGTG AAGACACCTC CGGAGCCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0223--Dioxygenase
KW-0408--Iron
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003347--JmjC_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS01359--ZF_PHD_1

Pfam

PF02373--JmjC

SMART

SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0051864--F:histone demethylase activity (H3-K36 specific)
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

cne:CNG00620

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002052	Ailuropoda melanoleuca	38.51	3.00e-58	219.00
IUUC-Apl-003192	Anas platyrhynchos	39.40	4.00e-62	231.00
IUUC-Aca-004576	Anolis carolinensis	39.10	3.00e-60	225.00
IUUC-Ath-007233	Arabidopsis thaliana	34.43	4.00e-05	43.10
IUUC-Ago-007912	Ashbya gossypii	31.48	2.00e-36	144.00
IUUC-Acl-008303	Aspergillus clavatus	33.11	7.00e-56	211.00
IUUC-Afl-008579	Aspergillus flavus	27.57	2.00e-17	82.80
IUUC-Afu-008903	Aspergillus fumigatus	34.08	1.00e-56	213.00
IUUC-Ani-009279	Aspergillus nidulans	33.41	4.00e-55	208.00
IUUC-Ang-009645	Aspergillus niger	33.56	3.00e-53	201.00
IUUC-Aor-010233	Aspergillus oryzae	33.11	9.00e-55	207.00
IUUC-Ate-010345	Aspergillus terreus	34.62	2.00e-56	212.00
IUUC-Ame-011753	Astyanax mexicanus	37.76	3.00e-58	219.00
IUUC-Bta-013531	Bos taurus	38.25	5.00e-58	218.00
IUUC-Bol-016000	Brassica oleracea	34.43	5.00e-05	42.40
IUUC-Bra-018090	Brassica rapa	34.43	5.00e-05	42.40
IUUC-Cel-018303	Caenorhabditis elegans	34.28	5.00e-45	174.00
IUUC-Cja-019030	Callithrix jacchus	38.51	2.00e-58	219.00
IUUC-Cfa-020644	Canis familiaris	38.51	1.00e-58	219.00
IUUC-Cpo-022055	Cavia porcellus	38.51	2.00e-58	219.00
IUUC-Csa-023379	Chlorocebus sabaeus	38.51	2.00e-58	219.00
IUUC-Cho-024541	Choloepus hoffmanni	31.34	1.00e-35	143.00
IUUC-Cin-025140	Ciona intestinalis	34.07	5.00e-49	187.00
IUUC-Csv-025861	Ciona savignyi	34.34	2.00e-51	195.00
IUUC-Cme-027118	Cyanidioschyzon merolae	34.64	2.00e-24	105.00
IUUC-Dre-028182	Danio rerio	38.99	3.00e-59	222.00
IUUC-Dno-029268	Dasypus novemcinctus	38.51	2.00e-58	219.00
IUUC-Dor-030736	Dipodomys ordii	37.05	9.00e-54	204.00
IUUC-Dse-031402	Dothistroma septosporum	34.78	2.00e-48	186.00
IUUC-Dme-032039	Drosophila melanogaster	37.01	4.00e-56	211.00
IUUC-Ete-032467	Echinops telfairi	38.51	1.00e-59	223.00
IUUC-Eca-033526	Equus caballus	38.51	2.00e-58	219.00
IUUC-Eeu-035273	Erinaceus europaeus	46.71	7.00e-42	164.00
IUUC-Fca-035532	Felis catus	38.51	2.00e-58	219.00
IUUC-Fal-037140	Ficedula albicollis	39.10	1.00e-61	229.00
IUUC-Gmo-039539	Gadus morhua	38.35	7.00e-59	220.00
IUUC-Gga-040418	Gallus gallus	39.40	1.00e-61	229.00
IUUC-Gac-041914	Gasterosteus aculeatus	38.51	3.00e-58	218.00
IUUC-Ggo-044712	Gorilla gorilla	33.72	3.00e-49	189.00
IUUC-Hsa-046180	Homo sapiens	38.51	1.00e-58	219.00
IUUC-Kpa-049384	Komagataella pastoris	32.54	3.00e-43	167.00
IUUC-Lch-049950	Latimeria chalumnae	37.88	1.00e-56	213.00
IUUC-Loc-051972	Lepisosteus oculatus	37.46	1.00e-54	206.00
IUUC-Lma-053190	Leptosphaeria maculans	31.71	2.00e-48	186.00
IUUC-Laf-053939	Loxodonta africana	38.51	1.00e-58	219.00
IUUC-Mcc-054600	Macaca mulatta	38.51	2.00e-58	219.00
IUUC-Meu-056259	Macropus eugenii	35.54	7.00e-52	197.00
IUUC-Mla-058890	Melampsora laricipopulina	41.34	1.00e-66	244.00
IUUC-Mga-059549	Meleagris gallopavo	39.40	6.00e-62	231.00
IUUC-Mvi-060481	Microbotryum violaceum	33.64	1.00e-73	270.00
IUUC-Mmr-060865	Microcebus murinus	38.51	2.00e-58	219.00
IUUC-Mdo-062567	Monodelphis domestica	39.10	3.00e-59	222.00
IUUC-Mmu-063782	Mus musculus	38.51	2.00e-58	219.00
IUUC-Mpu-066055	Mustela putorius furo	38.51	1.00e-58	219.00
IUUC-Mlu-067228	Myotis lucifugus	38.51	3.00e-58	218.00
IUUC-Nfi-068537	Neosartorya fischeri	33.63	4.00e-56	211.00
IUUC-Nle-069668	Nomascus leucogenys	38.51	2.00e-58	219.00
IUUC-Opr-070225	Ochotona princeps	38.51	2.00e-58	219.00
IUUC-Ont-071349	Oreochromis niloticus	38.05	8.00e-59	220.00
IUUC-Oan-073668	Ornithorhynchus anatinus	37.50	4.00e-53	199.00
IUUC-Ocu-074710	Oryctolagus cuniculus	38.51	2.00e-58	219.00
IUUC-Ola-087410	Oryzias latipes	37.95	5.00e-58	218.00
IUUC-Olu-087701	Ostreococcus lucimarinus	28.33	1.00e-04	40.40
IUUC-Oga-088644	Otolemur garnettii	38.51	2.00e-58	219.00
IUUC-Oar-089193	Ovis aries	38.21	6.00e-57	214.00
IUUC-Ptr-091523	Pan troglodytes	38.51	1.00e-58	219.00
IUUC-Pan-092415	Papio anubis	38.51	2.00e-58	219.00
IUUC-Psi-093114	Pelodiscus sinensis	38.51	6.00e-60	223.00
IUUC-Pma-094621	Petromyzon marinus	32.45	2.00e-48	184.00
IUUC-Pno-094984	Phaeosphaeria nodorum	36.45	2.00e-48	186.00
IUUC-Ppa-095609	Physcomitrella patens	43.57	5.00e-26	109.00
IUUC-Pfo-096695	Poecilia formosa	38.05	7.00e-59	220.00
IUUC-Pab-097907	Pongo abelii	38.55	4.00e-58	218.00
IUUC-Pca-100628	Procavia capensis	37.92	6.00e-40	157.00
IUUC-Pva-102416	Pteropus vampyrus	38.51	2.00e-58	219.00
IUUC-Pgr-103554	Puccinia graminis	39.12	9.00e-69	252.00
IUUC-Ptt-103859	Puccinia triticina	40.00	3.00e-68	251.00
IUUC-Pte-104241	Pyrenophora teres	36.77	9.00e-49	187.00
IUUC-Pyt-104741	Pyrenophora triticirepentis	36.77	2.00e-48	186.00
IUUC-Rno-105814	Rattus norvegicus	38.51	2.00e-58	219.00
IUUC-Sce-106445	Saccharomyces cerevisiae	36.17	3.00e-48	184.00
IUUC-Sha-106693	Sarcophilus harrisii	38.81	8.00e-59	220.00
IUUC-Sja-107763	Schizosaccharomyces japonicus	23.89	2.00e-28	119.00
IUUC-Spo-108120	Schizosaccharomyces pombe	25.56	1.00e-31	129.00
IUUC-Smo-109024	Selaginella moellendorffii	30.33	1.00e-36	146.00
IUUC-Sar-113568	Sorex araneus	38.21	1.00e-56	213.00
IUUC-Sre-115112	Sporisorium reilianum	31.78	5.00e-52	197.00
IUUC-Ssc-115432	Sus scrofa	38.21	2.00e-57	214.00
IUUC-Tgu-117298	Taeniopygia guttata	38.81	2.00e-60	225.00
IUUC-Tru-118423	Takifugu rubripes	38.69	3.00e-60	225.00
IUUC-Tsy-119293	Tarsius syrichta	37.61	5.00e-54	204.00
IUUC-Tni-120753	Tetraodon nigroviridis	35.91	8.00e-59	220.00
IUUC-Tme-127054	Tuber melanosporum	28.71	2.00e-36	146.00
IUUC-Tbe-128138	Tupaia belangeri	32.84	6.00e-44	171.00
IUUC-Ttr-128194	Tursiops truncatus	27.16	3.00e-38	152.00
IUUC-Uma-129458	Ustilago maydis	31.21	4.00e-53	200.00
IUUC-Vpa-130655	Vicugna pacos	35.52	4.00e-50	191.00
IUUC-Xtr-131839	Xenopus tropicalis	37.61	1.00e-57	215.00
IUUC-Xma-133499	Xiphophorus maculatus	38.05	4.00e-58	218.00
IUUC-Yli-134626	Yarrowia lipolytica	35.15	4.00e-45	173.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence