iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088449

Ensembl Protein ID

ENSOGAP00000001921.2

UniProt Accession

H0WK51; H0WK51_OTOGA

Genbank Protein ID

ENSOGAP00000001921

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03049002

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000002146.2	ENSOGAT00000002150.2	ENSOGAP00000001921.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-61	204.8	1129	1181

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy+a+n+deL++ kG  + v+   + d +W++g  e +g  GlfP+n+v+ 
   Q: 1129 QVIAMYDYTASNEDELSFSKGQLINVM--SKDDPDWWQG--EISGVTGLFPSNYVKM 1181
           6899**********************9..889*******..9*************85 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MISLSSTYVL GGPNMWAITS EERTKHDKQF DNLKPSGGYI TGDQARTFFL QSGLPAPVLA 60
EIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQQLPIVLP PIMKQPPMFS PLISARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTTCTT TGTCTTCCAC TTATGTTTTA GGAGGGCCAA ACATGTGGGC TATTACCTCT 60
GAGGAACGTA CTAAGCATGA CAAGCAGTTT GATAACCTCA AACCATCAGG AGGTTACATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	92.00	0.00e+00	2133.00
IUUC-Apl-004205	Anas platyrhynchos	79.27	0.00e+00	2416.00
IUUC-Aca-004287	Anolis carolinensis	84.66	0.00e+00	1667.00
IUUC-Ame-011759	Astyanax mexicanus	64.78	0.00e+00	1252.00
IUUC-Bta-013248	Bos taurus	89.86	0.00e+00	2048.00
IUUC-Cel-018490	Caenorhabditis elegans	33.85	4.00e-55	209.00
IUUC-Cfa-020628	Canis familiaris	91.92	0.00e+00	2147.00
IUUC-Cpo-022427	Cavia porcellus	80.29	0.00e+00	2559.00
IUUC-Csa-023122	Chlorocebus sabaeus	91.27	0.00e+00	2148.00
IUUC-Cgl-026697	Colletotrichum gloeosporioides	40.35	2.00e-08	55.10
IUUC-Dre-027849	Danio rerio	64.54	0.00e+00	1208.00
IUUC-Dno-029419	Dasypus novemcinctus	91.17	0.00e+00	2138.00
IUUC-Dor-030504	Dipodomys ordii	76.23	0.00e+00	1702.00
IUUC-Dme-032099	Drosophila melanogaster	33.12	2.00e-56	214.00
IUUC-Eca-034196	Equus caballus	89.71	0.00e+00	2033.00
IUUC-Eeu-034972	Erinaceus europaeus	69.08	0.00e+00	641.00
IUUC-Fca-035757	Felis catus	92.80	0.00e+00	2152.00
IUUC-Fal-037531	Ficedula albicollis	88.49	0.00e+00	1747.00
IUUC-Gga-041012	Gallus gallus	78.90	0.00e+00	1892.00
IUUC-Ggo-045405	Gorilla gorilla	89.33	0.00e+00	2669.00
IUUC-Hsa-046833	Homo sapiens	93.47	0.00e+00	2132.00
IUUC-Lch-050094	Latimeria chalumnae	73.30	0.00e+00	1668.00
IUUC-Loc-052646	Lepisosteus oculatus	72.77	0.00e+00	1454.00
IUUC-Mcc-054709	Macaca mulatta	93.23	0.00e+00	2159.00
IUUC-Meu-056396	Macropus eugenii	80.55	0.00e+00	1545.00
IUUC-Mla-059128	Melampsora laricipopulina	34.81	8.00e-40	160.00
IUUC-Mga-059997	Meleagris gallopavo	82.84	0.00e+00	2007.00
IUUC-Mvi-060268	Microbotryum violaceum	30.59	5.00e-46	180.00
IUUC-Mmr-060891	Microcebus murinus	91.91	0.00e+00	2185.00
IUUC-Mmu-064226	Mus musculus	85.25	0.00e+00	2106.00
IUUC-Mpu-066431	Mustela putorius furo	89.70	0.00e+00	2124.00
IUUC-Mlu-068190	Myotis lucifugus	91.67	0.00e+00	2123.00
IUUC-Nle-070116	Nomascus leucogenys	88.68	0.00e+00	1677.00
IUUC-Opr-070815	Ochotona princeps	78.02	0.00e+00	1731.00
IUUC-Ont-072464	Oreochromis niloticus	65.36	0.00e+00	1236.00
IUUC-Ocu-073856	Oryctolagus cuniculus	77.37	0.00e+00	1855.00
IUUC-Ola-086482	Oryzias latipes	60.92	0.00e+00	1229.00
IUUC-Oar-090275	Ovis aries	90.35	0.00e+00	2087.00
IUUC-Ptr-091667	Pan troglodytes	92.98	0.00e+00	2120.00
IUUC-Pan-091723	Papio anubis	88.05	0.00e+00	1830.00
IUUC-Psi-093136	Pelodiscus sinensis	81.32	0.00e+00	1919.00
IUUC-Pab-098755	Pongo abelii	90.86	0.00e+00	2052.00
IUUC-Pca-101134	Procavia capensis	86.12	0.00e+00	1500.00
IUUC-Pva-102433	Pteropus vampyrus	81.77	0.00e+00	1875.00
IUUC-Pgr-103473	Puccinia graminis	29.97	7.00e-38	154.00
IUUC-Rno-105691	Rattus norvegicus	88.88	0.00e+00	2156.00
IUUC-Sar-112978	Sorex araneus	86.11	0.00e+00	1363.00
IUUC-Sre-115028	Sporisorium reilianum	36.71	5.00e-34	140.00
IUUC-Ssc-115562	Sus scrofa	84.46	0.00e+00	1914.00
IUUC-Tgu-116758	Taeniopygia guttata	81.83	0.00e+00	1984.00
IUUC-Tni-119958	Tetraodon nigroviridis	54.88	0.00e+00	1663.00
IUUC-Tbe-127477	Tupaia belangeri	92.25	0.00e+00	760.00
IUUC-Ttr-129196	Tursiops truncatus	87.80	0.00e+00	2024.00
IUUC-Uma-129456	Ustilago maydis	32.30	5.00e-32	134.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence