iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067533

Ensembl Protein ID

ENSMLUP00000016168.2

UniProt Accession

G1PXJ5; G1PXJ5_MYOLU

Genbank Protein ID

ENSMLUP00000016168

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02021017

Gene Name

SLX4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000017724.2	ENSMLUT00000017728.2	ENSMLUP00000016168.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	8.10e-06	26.2	510	579
UBD/ZnF/UBZ	5.40e-09	36.2	118	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvg.geeffahkivLaasSsvFyalflme..le.es...ksklmveikdvqpevfrallkFlYtgk 64
           +Dv+++ + ge+  ahk vL a+++ +    ++e  +  e    + + +v ++dv+ e+ ra+l++lYt  
   Q: 510  SDVQFQMDnGEVLYAHKFVLYARCPLLIQYVNSEgfFAvEDgdlR-TQRVLLSDVSTEAARAFLHYLYTAD 579
           69*************************998854322333335657.999********************75 PP

UBD/ZnF/UBZ

   S: 2    lvCPvCqkm...vdqtdfeeHlDeCl 24
           ++C++Cqk    +++t++e+H+++Cl
   Q: 118  FFCQICQKNlsaMNVTRREQHVNRCL 143
           89***********************8 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

SSADAAPNGD SQPPPCLTAT VPSPSKPRAA EMVLQRMQQF KRADPARLKH ASEGCSLQPA 60
LEENVPKDPR GAIMVGNGSG PWLPATESDT AVALALQQEL GQEGATAPGD SLEEKGLFFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCTCTGCAG ATGCTGCTCC TAACGGTGAC TCCCAGCCTC CTCCCTGTCT GACTGCTACA 60
GTGCCAAGTC CCTCCAAACC CCGGGCGGCG GAGATGGTCC TACAGCGAAT GCAGCAGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR018574--Structure-sp_endonuc_su_Slx4

PROSITE

PS50097--BTB

Pfam

PF00651--BTB
PF09494--Slx4

SMART

SM00225--BTB

Gene Ontology

GO:0030054--C:cell junction
GO:0005829--C:cytosol
GO:0070522--C:ERCC4-ERCC1 complex
GO:0048476--C:Holliday junction resolvase complex
GO:0000790--C:nuclear chromatin
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0033557--C:Slx1-Slx4 complex
GO:0048257--F:3'-flap endonuclease activity
GO:0017108--F:5'-flap endonuclease activity
GO:0008821--F:crossover junction endodeoxyribonuclease activity
GO:0008047--F:enzyme activator activity
GO:0010792--P:DNA double-strand break processing involved in repair via single-strand annealing
GO:0006260--P:DNA replication
GO:0000724--P:double-strand break repair via homologous recombination
GO:1904357--P:negative regulation of telomere maintenance via telomere lengthening
GO:0006289--P:nucleotide-excision repair
GO:1904431--P:positive regulation of t-circle formation
GO:0072429--P:response to intra-S DNA damage checkpoint signaling
GO:0090656--P:t-circle formation
GO:0061820--P:telomeric D-loop disassembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001225	Ailuropoda melanoleuca	71.11	0.00e+00	1788.00
IUUC-Apl-003261	Anas platyrhynchos	36.13	2.00e-170	593.00
IUUC-Aca-004455	Anolis carolinensis	71.93	1.00e-19	87.00
IUUC-Acl-008026	Aspergillus clavatus	32.76	4.70e-01	30.40
IUUC-Ame-010993	Astyanax mexicanus	39.64	7.00e-13	67.00
IUUC-Bta-013472	Bos taurus	64.43	0.00e+00	1416.00
IUUC-Cel-018663	Caenorhabditis elegans	38.64	5.00e-03	36.60
IUUC-Cja-019406	Callithrix jacchus	61.88	0.00e+00	1422.00
IUUC-Cfa-020129	Canis familiaris	66.18	0.00e+00	1579.00
IUUC-Cpo-021944	Cavia porcellus	58.29	0.00e+00	1340.00
IUUC-Csa-023941	Chlorocebus sabaeus	58.80	0.00e+00	712.00
IUUC-Cho-024847	Choloepus hoffmanni	71.19	3.00e-121	430.00
IUUC-Cin-025405	Ciona intestinalis	42.31	2.00e-07	50.10
IUUC-Csv-025916	Ciona savignyi	38.98	7.00e-09	53.90
IUUC-Dre-027764	Danio rerio	33.99	2.00e-72	268.00
IUUC-Dno-030083	Dasypus novemcinctus	58.04	0.00e+00	1248.00
IUUC-Dor-031129	Dipodomys ordii	53.71	0.00e+00	684.00
IUUC-Dse-031510	Dothistroma septosporum	36.11	5.70e-02	33.50
IUUC-Ete-032536	Echinops telfairi	45.99	2.00e-93	337.00
IUUC-Eca-033407	Equus caballus	75.31	0.00e+00	1682.00
IUUC-Eeu-034473	Erinaceus europaeus	55.33	2.00e-32	135.00
IUUC-Fca-035730	Felis catus	67.14	0.00e+00	1674.00
IUUC-Fal-036850	Ficedula albicollis	36.97	2.00e-177	617.00
IUUC-Gmo-038677	Gadus morhua	43.09	1.00e-31	131.00
IUUC-Gga-041088	Gallus gallus	45.35	1.00e-133	471.00
IUUC-Gac-041824	Gasterosteus aculeatus	41.56	3.00e-13	68.60
IUUC-Ggo-045642	Gorilla gorilla	63.00	0.00e+00	1391.00
IUUC-Hsa-047035	Homo sapiens	63.06	0.00e+00	1505.00
IUUC-Itr-049010	Ictidomys tridecemlineatus	61.44	0.00e+00	1422.00
IUUC-Kpa-049328	Komagataella pastoris	29.03	4.40e-02	33.10
IUUC-Lch-050364	Latimeria chalumnae	41.67	2.00e-82	301.00
IUUC-Loc-052423	Lepisosteus oculatus	42.09	9.00e-43	169.00
IUUC-Laf-053910	Loxodonta africana	59.18	0.00e+00	1384.00
IUUC-Mcc-055883	Macaca mulatta	63.47	0.00e+00	1540.00
IUUC-Meu-056224	Macropus eugenii	50.26	3.00e-86	314.00
IUUC-Mga-059880	Meleagris gallopavo	45.61	1.00e-134	475.00
IUUC-Mvi-060510	Microbotryum violaceum	33.33	7.00e-04	39.70
IUUC-Mmr-061715	Microcebus murinus	63.51	0.00e+00	1540.00
IUUC-Mdo-062426	Monodelphis domestica	45.15	0.00e+00	734.00
IUUC-Mmu-063947	Mus musculus	58.12	0.00e+00	1344.00
IUUC-Mpu-066184	Mustela putorius furo	67.75	0.00e+00	1697.00
IUUC-Nle-069204	Nomascus leucogenys	62.56	0.00e+00	1483.00
IUUC-Opr-070377	Ochotona princeps	65.00	0.00e+00	781.00
IUUC-Ont-072551	Oreochromis niloticus	34.37	8.00e-68	253.00
IUUC-Oan-073350	Ornithorhynchus anatinus	54.34	2.00e-95	342.00
IUUC-Ocu-074915	Oryctolagus cuniculus	61.93	0.00e+00	820.00
IUUC-Ola-087360	Oryzias latipes	45.74	6.00e-31	127.00
IUUC-Oga-089106	Otolemur garnettii	61.97	0.00e+00	1297.00
IUUC-Oar-089289	Ovis aries	66.08	0.00e+00	998.00
IUUC-Ptr-091469	Pan troglodytes	63.30	0.00e+00	1499.00
IUUC-Pan-091841	Papio anubis	61.53	0.00e+00	1246.00
IUUC-Psi-093842	Pelodiscus sinensis	46.86	7.00e-126	446.00
IUUC-Pma-094732	Petromyzon marinus	55.77	7.00e-09	53.50
IUUC-Pfo-097299	Poecilia formosa	41.44	2.00e-33	138.00
IUUC-Pab-098271	Pongo abelii	63.24	0.00e+00	1495.00
IUUC-Pca-100721	Procavia capensis	56.21	0.00e+00	816.00
IUUC-Pva-102276	Pteropus vampyrus	76.52	0.00e+00	2063.00
IUUC-Rno-105619	Rattus norvegicus	57.85	0.00e+00	1337.00
IUUC-Sha-106722	Sarcophilus harrisii	47.48	0.00e+00	944.00
IUUC-Sar-113673	Sorex araneus	65.42	4.00e-86	313.00
IUUC-Ssc-115383	Sus scrofa	64.97	0.00e+00	1431.00
IUUC-Tgu-117243	Taeniopygia guttata	50.25	3.00e-89	322.00
IUUC-Tru-118092	Takifugu rubripes	70.18	2.00e-17	82.80
IUUC-Tsy-119362	Tarsius syrichta	58.43	5.00e-166	579.00
IUUC-Tni-120380	Tetraodon nigroviridis	68.97	1.00e-17	83.60
IUUC-Tbe-127404	Tupaia belangeri	49.07	0.00e+00	700.00
IUUC-Ttr-128317	Tursiops truncatus	69.29	0.00e+00	1565.00
IUUC-Uma-129640	Ustilago maydis	33.90	5.00e-04	38.50
IUUC-Xtr-132533	Xenopus tropicalis	39.07	3.00e-89	324.00
IUUC-Xma-134059	Xiphophorus maculatus	38.64	5.00e-33	137.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence