iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022332

Ensembl Protein ID

ENSCPOP00000010518.2

UniProt Accession

H0VJS6; H0VJS6_CAVPO

Genbank Protein ID

ENSCPOP00000010518

Protein Name

Histone acetyltransferase

Genbank Nucleotide ID

AAKN02048148

Gene Name

KAT6A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000011695.3	ENSCPOT00000011808.2	ENSCPOP00000010518.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-09	38.3	64	113

Active Site

Position(s)	Description	Evidence
480	Proton donor/acceptor	{ECO:0000256\|PIRSR:PIRSR602717-51}

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           k C  C+++g++ ++++ C+ C++ fH +C  ++  + +p+   wiC+ Cr 
   Q: 64   KTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPP-LTRMPKGM-WICQICRP 113
           68999******99*********************.9*****97.******85 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

QPVAEPIPIC SFCLGTKEQN REKKPEELIS CADCGNSGHP SCLKFSPELT VRVKALRWQC 60
IECKTCSSCR DQGKNADNML FCDSCDRGFH MECCDPPLTR MPKGMWICQI CRPRKKGRKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCCAGTTG CTGAACCAAT CCCCATCTGT AGTTTTTGTC TTGGTACAAA AGAACAAAAC 60
CGGGAAAAGA AGCCAGAGGA ACTCATCTCC TGTGCAGACT GTGGCAACAG TGGTACGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR002717--HAT_MYST-type
IPR031280--KAT6A
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51726--MYST_HAT
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01853--MOZ_SAS
PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0003677--F:DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0043966--P:histone H3 acetylation
GO:0030099--P:myeloid cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001219	Ailuropoda melanoleuca	86.70	0.00e+00	1603.00
IUUC-Aca-004549	Anolis carolinensis	67.18	0.00e+00	1268.00
IUUC-Ame-010711	Astyanax mexicanus	64.78	4.00e-128	453.00
IUUC-Bta-013426	Bos taurus	85.64	0.00e+00	1563.00
IUUC-Cja-019124	Callithrix jacchus	89.51	0.00e+00	2496.00
IUUC-Cfa-021165	Canis familiaris	85.70	0.00e+00	2002.00
IUUC-Cne-026801	Cryptococcus neoformans	63.59	1.00e-73	271.00
IUUC-Dre-028624	Danio rerio	80.15	0.00e+00	677.00
IUUC-Dno-029878	Dasypus novemcinctus	79.78	0.00e+00	1843.00
IUUC-Ete-032342	Echinops telfairi	88.37	0.00e+00	1424.00
IUUC-Eca-033925	Equus caballus	84.73	0.00e+00	1977.00
IUUC-Fca-035985	Felis catus	85.21	0.00e+00	2025.00
IUUC-Gmo-039182	Gadus morhua	76.69	0.00e+00	921.00
IUUC-Gga-041028	Gallus gallus	77.01	0.00e+00	1440.00
IUUC-Gac-042131	Gasterosteus aculeatus	76.35	0.00e+00	941.00
IUUC-Ggo-044664	Gorilla gorilla	88.37	0.00e+00	1595.00
IUUC-Hsa-046832	Homo sapiens	88.37	0.00e+00	1596.00
IUUC-Loc-052537	Lepisosteus oculatus	78.43	0.00e+00	969.00
IUUC-Laf-053686	Loxodonta africana	84.08	0.00e+00	1965.00
IUUC-Mcc-055429	Macaca mulatta	88.57	0.00e+00	1601.00
IUUC-Mvi-060531	Microbotryum violaceum	54.91	6.00e-72	266.00
IUUC-Mmr-061249	Microcebus murinus	86.13	0.00e+00	1605.00
IUUC-Mdo-062826	Monodelphis domestica	73.25	0.00e+00	1591.00
IUUC-Mmu-063474	Mus musculus	85.36	0.00e+00	1631.00
IUUC-Mpu-066585	Mustela putorius furo	84.98	0.00e+00	2011.00
IUUC-Mlu-066965	Myotis lucifugus	83.52	0.00e+00	1888.00
IUUC-Nle-069270	Nomascus leucogenys	88.47	0.00e+00	1599.00
IUUC-Opr-070963	Ochotona princeps	70.86	0.00e+00	1218.00
IUUC-Ont-071466	Oreochromis niloticus	82.28	2.00e-171	597.00
IUUC-Oan-073367	Ornithorhynchus anatinus	80.62	0.00e+00	1501.00
IUUC-Ocu-074100	Oryctolagus cuniculus	78.07	0.00e+00	1385.00
IUUC-Ola-087293	Oryzias latipes	74.75	0.00e+00	924.00
IUUC-Oga-089052	Otolemur garnettii	93.19	0.00e+00	929.00
IUUC-Oar-089692	Ovis aries	83.08	0.00e+00	1488.00
IUUC-Ptr-091107	Pan troglodytes	88.27	0.00e+00	1573.00
IUUC-Pan-092524	Papio anubis	88.29	0.00e+00	1598.00
IUUC-Pfo-096641	Poecilia formosa	74.24	0.00e+00	918.00
IUUC-Pab-098311	Pongo abelii	88.10	0.00e+00	1597.00
IUUC-Pca-100810	Procavia capensis	83.32	0.00e+00	1516.00
IUUC-Pgr-103522	Puccinia graminis	50.40	2.00e-68	254.00
IUUC-Pyt-104594	Pyrenophora triticirepentis	36.30	3.00e-45	177.00
IUUC-Rno-104990	Rattus norvegicus	83.95	0.00e+00	1566.00
IUUC-Sha-106816	Sarcophilus harrisii	80.26	0.00e+00	1893.00
IUUC-Sre-115066	Sporisorium reilianum	55.98	4.00e-78	286.00
IUUC-Tgu-116639	Taeniopygia guttata	77.23	0.00e+00	1402.00
IUUC-Tru-118571	Takifugu rubripes	77.50	0.00e+00	951.00
IUUC-Tni-119936	Tetraodon nigroviridis	77.66	0.00e+00	965.00
IUUC-Tbe-127928	Tupaia belangeri	96.72	0.00e+00	1249.00
IUUC-Uma-129445	Ustilago maydis	56.84	2.00e-79	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence