iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
dbPPT	dbPTM
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	16339806

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	3.80e-07	31.4	118	160

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl++f  ++ +++ p C Hvfh  C+ +w       + + +CPlCr
   Q: 118  CPVCLNEFedDETLRLIPqCCHVFHPGCIDAW------LRSQTTCPLCR 160
           ********65333888889*************......**********8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8, UBC10, UBC11, UBC28 and UBC29 in vitro.

Protein Sequence
(Fasta)

MVVMSRVSFY SSFLLLLLEV VVASSEFDDE GRTSFSPTTA IIMIVLVSVF FALGCISVYM 60
RRCLQHALGM DSGGGPGNWL NVRQTTEPGL DASVIETFPT FPYSTVKTLR IGKEALECPV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTTTATAA AGCTCCTTCA CCGGTAAAAG CCTTGGTCCT CATGAAACCG GGAAGCCCAA 60
GTACTTACTT CCACCATCAA ATCGTCAAAC CATTTGCAAC CATCGATGGT GGTCATGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0033591--P:response to L-ascorbic acid
GO:0009416--P:response to light stimulus

KEGG

ath:AT1G22500

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006270	Arabidopsis lyrata	82.46	0.00e+00	629.00
IUUC-Bol-015608	Brassica oleracea	77.02	4.00e-169	586.00
IUUC-Bra-017466	Brassica rapa	77.96	1.00e-166	578.00
IUUC-Pop-099890	Populus trichocarpa	42.91	9.00e-47	179.00
IUUC-Smo-108906	Selaginella moellendorffii	52.56	3.00e-24	102.00
IUUC-Sly-111277	Solanum lycopersicum	38.80	1.00e-63	236.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence