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Tag Content
iUUCD ID IUUC-Mtr-057961
Ensembl Protein ID AET01741
UniProt Accession Q1SF86; ATG12_MEDTR
Genbank Protein ID AET01741
Protein Name Ubiquitin-like protein ATG12; Autophagy-related protein 12
Genbank Nucleotide ID AC144645
Gene Name ATG12; APG12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
MTR_8g020500 KEH18474 KEH18474
MTR_8g020500 AET01741 AET01741
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UBL/ATG12 44.32 4.00e-17 84.00 IUUC-Hsa-046903
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Medicago truncatula
Functional Description
(View)

Functional Description


     Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system is essential for its function. ATG12/ATG5 conjugate has an essential role in plant nutrient recycling (By similarity).
 Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system is essential for its function. ATG12/ATG5 conjugate has an essential role in plant nutrient recycling (By similarity).
Protein Sequence
(Fasta)
MAAAESPTSV RKVVVHLRAT GDAPILKQSK FKIAGTDKFA KVIDFLRRQL HRESLFVYVN 60
SAFSPNPDEL VIDLYNNFGF DGKLVVNYAC SMAWG 95
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Protein Fasta Sequence


>IUUC-Mtr-057961|ULD,ATG12|Medicago truncatula
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Nucleotide Sequence
(Fasta)
CTTTAAATTT ACTTGAAATG ATTTAAAAAA GAAAAAAGAT TAGTTCTTCT TCGTAGGAAA 60
TAGGGATTGA AATTGGTTCT TCTTCTTCTT CTTCAGTGTT CCTTCTTCTC CATGGCTGCT 120
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Nucleotide Fasta Sequence


>IUUC-Mtr-057961|ULD,ATG12|Medicago truncatula
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Sequence Source Ensembl
Keyword

KW-0072--Autophagy
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0653--Protein transport
KW-0813--Transport
KW-0833--Ubl conjugation pathway
Interpro

IPR007242--Atg12
IPR029071--Ubiquitin-rel_dom
Pfam

PF04110--APG12
Gene Ontology

GO:0005737--C:cytoplasm
GO:0000045--P:autophagosome assembly
GO:0015031--P:protein transport
KEGG mtr:MTR_8g020500
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001177 Aegilops tauschii 71.58 1.00e-37 146.00
IUUC-Aml-002116 Ailuropoda melanoleuca 45.45 5.00e-18 83.20
IUUC-Atr-002615 Amborella trichopoda 91.40 2.00e-48 182.00
IUUC-Apl-003753 Anas platyrhynchos 55.00 2.00e-09 52.80
IUUC-Aca-005231 Anolis carolinensis 45.45 2.00e-14 70.90
IUUC-Aly-006172 Arabidopsis lyrata 90.22 1.00e-45 173.00
IUUC-Ath-006953 Arabidopsis thaliana 87.10 3.00e-46 175.00
IUUC-Ago-007970 Ashbya gossypii 29.76 1.00e-04 38.50
IUUC-Acl-008072 Aspergillus clavatus 42.53 6.00e-14 68.60
IUUC-Afl-008725 Aspergillus flavus 42.53 5.00e-14 70.10
IUUC-Afu-008967 Aspergillus fumigatus 42.53 1.00e-13 68.60
IUUC-Ani-009248 Aspergillus nidulans 41.38 3.00e-13 67.40
IUUC-Ang-009684 Aspergillus niger 39.81 1.00e-13 68.60
IUUC-Aor-009947 Aspergillus oryzae 42.53 5.00e-14 70.10
IUUC-Ame-011656 Astyanax mexicanus 42.05 2.00e-15 73.60
IUUC-Bgr-012174 Blumeria graminis 42.70 3.00e-13 66.60
IUUC-Bta-012483 Bos taurus 44.32 3.00e-18 83.20
IUUC-Bci-013755 Botrytis cinerea 38.54 8.00e-12 61.60
IUUC-Bdi-014156 Brachypodium distachyon 73.68 6.00e-40 154.00
IUUC-Bol-015683 Brassica oleracea 88.42 2.00e-45 172.00
IUUC-Bra-016802 Brassica rapa 88.64 2.00e-43 166.00
IUUC-Cel-018242 Caenorhabditis elegans 35.16 2.00e-08 50.10
IUUC-Cja-019514 Callithrix jacchus 44.32 6.00e-18 83.20
IUUC-Cfa-020748 Canis familiaris 45.45 3.00e-18 83.60
IUUC-Cpo-021965 Cavia porcellus 45.45 4.00e-18 83.20
IUUC-Cre-023009 Chlamydomonas reinhardtii 48.42 8.00e-20 87.40
IUUC-Csa-023494 Chlorocebus sabaeus 44.32 3.00e-18 83.60
IUUC-Cho-024631 Choloepus hoffmanni 44.32 8.00e-18 82.40
IUUC-Cin-025609 Ciona intestinalis 49.43 6.00e-18 81.30
IUUC-Cgl-026722 Colletotrichum gloeosporioides 41.57 2.00e-13 67.40
IUUC-Dre-027479 Danio rerio 41.05 3.00e-16 76.60
IUUC-Dno-029693 Dasypus novemcinctus 39.77 2.00e-12 63.90
IUUC-Dse-031440 Dothistroma septosporum 41.38 5.00e-14 69.30
IUUC-Dme-031892 Drosophila melanogaster 34.48 5.00e-13 65.10
IUUC-Ete-032550 Echinops telfairi 41.67 2.00e-17 80.10
IUUC-Eca-033553 Equus caballus 44.32 3.00e-18 83.60
IUUC-Fca-036524 Felis catus 44.83 7.00e-18 82.40
IUUC-Fal-036942 Ficedula albicollis 43.02 4.00e-17 78.20
IUUC-Fox-037753 Fusarium oxysporum 43.18 8.00e-14 68.90
IUUC-Gmo-039498 Gadus morhua 42.05 2.00e-15 73.60
IUUC-Ggr-039852 Gaeumannomyces graminis 40.45 2.00e-11 61.60
IUUC-Gga-041263 Gallus gallus 44.32 6.00e-18 82.40
IUUC-Gac-042346 Gasterosteus aculeatus 42.86 8.00e-15 71.60
IUUC-Gma-042896 Glycine max 93.55 1.00e-49 186.00
IUUC-Ggo-045601 Gorilla gorilla 44.32 6.00e-18 83.20
IUUC-Hsa-046903 Homo sapiens 44.32 3.00e-18 83.60
IUUC-Hvu-047239 Hordeum vulgare 72.63 6.00e-38 147.00
IUUC-Itr-048445 Ictidomys tridecemlineatus 41.84 4.00e-18 83.20
IUUC-Kpa-049355 Komagataella pastoris 30.61 2.00e-10 57.40
IUUC-Lch-050619 Latimeria chalumnae 42.05 6.00e-17 79.00
IUUC-Loc-052102 Lepisosteus oculatus 50.00 4.00e-03 32.00
IUUC-Lma-053299 Leptosphaeria maculans 37.84 6.00e-09 52.00
IUUC-Laf-054205 Loxodonta africana 42.86 6.00e-19 85.50
IUUC-Meu-056804 Macropus eugenii 45.45 2.00e-18 83.60
IUUC-Mor-057052 Magnaporthe oryzae 38.89 3.00e-11 60.80
IUUC-Mla-059045 Melampsora laricipopulina 48.31 6.00e-22 95.10
IUUC-Mvi-060360 Microbotryum violaceum 50.57 3.00e-22 96.30
IUUC-Mmr-061654 Microcebus murinus 44.32 2.00e-18 83.60
IUUC-Mdo-062649 Monodelphis domestica 44.32 3.00e-18 83.20
IUUC-Mmu-064105 Mus musculus 44.32 3.00e-18 83.20
IUUC-Mac-065532 Musa acuminata 88.17 2.00e-47 178.00
IUUC-Mpu-066269 Mustela putorius furo 45.45 1.00e-18 84.30
IUUC-Mlu-067631 Myotis lucifugus 44.32 5.00e-18 82.80
IUUC-Nfi-068468 Neosartorya fischeri 42.53 7.00e-14 68.20
IUUC-Ncr-068750 Neurospora crassa 34.83 2.00e-10 58.20
IUUC-Nle-069483 Nomascus leucogenys 44.32 5.00e-18 83.20
IUUC-Opr-070936 Ochotona princeps 41.84 1.00e-17 82.00
IUUC-Obr-076322 Oryza brachyantha 73.68 2.00e-39 152.00
IUUC-Ogl-077226 Oryza glaberrima 76.25 5.00e-36 141.00
IUUC-Oin-079220 Oryza indica 75.00 2.00e-27 112.00
IUUC-Olo-080688 Oryza longistaminata 76.25 5.00e-36 141.00
IUUC-Ome-081265 Oryza meridionalis 76.25 5.00e-36 141.00
IUUC-Oru-084342 Oryza rufipogon 76.47 6.00e-38 149.00
IUUC-Osa-086212 Oryza sativa 76.25 5.00e-36 141.00
IUUC-Ola-087277 Oryzias latipes 42.05 1.00e-15 73.90
IUUC-Olu-087780 Ostreococcus lucimarinus 40.45 2.00e-14 69.30
IUUC-Oga-088175 Otolemur garnettii 44.32 2.00e-18 84.00
IUUC-Oar-089477 Ovis aries 44.32 7.00e-18 82.40
IUUC-Ptr-091129 Pan troglodytes 44.32 6.00e-18 82.80
IUUC-Psi-093351 Pelodiscus sinensis 43.30 4.00e-18 83.20
IUUC-Pno-094948 Phaeosphaeria nodorum 36.36 2.00e-08 50.80
IUUC-Ppa-095788 Physcomitrella patens 77.08 4.00e-41 158.00
IUUC-Pfo-096993 Poecilia formosa 35.40 2.00e-14 69.70
IUUC-Pab-098502 Pongo abelii 44.32 6.00e-18 83.20
IUUC-Pop-098819 Populus trichocarpa 79.12 2.00e-42 162.00
IUUC-Pca-100144 Procavia capensis 31.82 2.00e-07 48.10
IUUC-Ppe-101560 Prunus persica 93.90 2.00e-43 166.00
IUUC-Pva-102810 Pteropus vampyrus 39.13 4.00e-10 56.60
IUUC-Pgr-103531 Puccinia graminis 50.57 5.00e-22 95.50
IUUC-Ptt-103753 Puccinia triticina 50.57 7.00e-22 94.70
IUUC-Pyt-104733 Pyrenophora triticirepentis 44.19 5.00e-14 69.30
IUUC-Rno-106072 Rattus norvegicus 46.59 4.00e-19 86.30
IUUC-Sce-106275 Saccharomyces cerevisiae 32.18 1.00e-11 62.00
IUUC-Sha-107554 Sarcophilus harrisii 43.88 1.00e-18 85.10
IUUC-Sja-107682 Schizosaccharomyces japonicus 35.23 2.00e-13 67.00
IUUC-Spo-108275 Schizosaccharomyces pombe 40.91 2.00e-17 80.90
IUUC-Smo-109151 Selaginella moellendorffii 56.63 2.00e-24 102.00
IUUC-Sit-110270 Setaria italica 83.53 3.00e-40 155.00
IUUC-Sly-111862 Solanum lycopersicum 95.29 3.00e-46 174.00
IUUC-Stu-112663 Solanum tuberosum 93.18 3.00e-21 92.80
IUUC-Sbi-114148 Sorghum bicolor 83.53 3.00e-40 155.00
IUUC-Sre-115216 Sporisorium reilianum 45.98 7.00e-20 88.60
IUUC-Ssc-116051 Sus scrofa 44.32 3.00e-18 83.60
IUUC-Tgu-117008 Taeniopygia guttata 28.95 2.60e-02 29.60
IUUC-Tru-118466 Takifugu rubripes 43.90 5.00e-15 71.60
IUUC-Tsy-119334 Tarsius syrichta 43.18 5.00e-14 70.10
IUUC-Tni-119792 Tetraodon nigroviridis 43.90 2.00e-15 72.80
IUUC-Tca-121861 Theobroma cacao 95.70 2.00e-50 189.00
IUUC-Tvi-122499 Trichoderma virens 44.32 4.00e-14 69.30
IUUC-Tae-123431 Triticum aestivum 71.58 1.00e-37 146.00
IUUC-Tme-126934 Tuber melanosporum 36.96 1.00e-12 65.10
IUUC-Ttr-129001 Tursiops truncatus 42.05 2.00e-13 67.80
IUUC-Uma-129324 Ustilago maydis 47.13 3.00e-20 90.10
IUUC-Vda-129846 Verticillium dahliae 40.91 4.00e-13 66.60
IUUC-Vpa-130202 Vicugna pacos 57.50 4.00e-10 57.00
IUUC-Vvi-131474 Vitis vinifera 88.61 6.00e-37 145.00
IUUC-Xtr-132782 Xenopus tropicalis 44.90 9.00e-19 85.10
IUUC-Xma-134140 Xiphophorus maculatus 36.28 6.00e-15 72.00
IUUC-Yli-134517 Yarrowia lipolytica 40.00 3.00e-12 64.30
IUUC-Zma-134764 Zea mays 83.53 2.00e-40 155.00
Created Date 25-Jun-2017

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