• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
iUUCD ID IUUC-Pno-094948
Ensembl Protein ID SNOT_06553
UniProt Accession Q0UNW1; ATG12_PHANO
Genbank Protein ID EAT86384.2
Protein Name Ubiquitin-like protein ATG12; Autophagy-related protein 12
Genbank Nucleotide ID CH445333
Gene Name ATG12; SNOG_06553
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SNOG_06553 SNOT_06553 SNOT_06553
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UBL/ATG12 28.12 1.00e-03 39.70 IUUC-Hsa-046903
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Phaeosphaeria nodorum
Functional Description
(View)

Functional Description


     Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
 Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
Protein Sequence
(Fasta)
MSAQEERIPE DDDTTEAPLT MAASVVLTNL PRDASKALET AGSLNVQKIR LHPIGSAPAL 60
TQRVFKLSTN QRFDTIVRFL RKRLGVKEHE SVFCYVGSVF APGLDEGVGG LWSVSCDFYF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pno-094948|ULD,ATG12|Phaeosphaeria nodorum
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCAGCCC AAGAAGAACG AATACCAGAA GACGACGACA CGACCGAAGC GCCACTCACC 60
ATGGCCGCAT CCGTCGTCCT GACAAATCTC CCGCGCGACG CATCCAAAGC CCTCGAAACA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pno-094948|ULD,ATG12|Phaeosphaeria nodorum
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0833--Ubl conjugation pathway
Interpro

IPR007242--Atg12
IPR029071--Ubiquitin-rel_dom
Pfam

PF04110--APG12
Gene Ontology

GO:0034274--C:Atg12-Atg5-Atg16 complex
GO:0034045--C:pre-autophagosomal structure membrane
GO:0019776--F:Atg8 ligase activity
GO:0000045--P:autophagosome assembly
GO:0006501--P:C-terminal protein lipidation
GO:0000422--P:mitophagy
GO:0044804--P:nucleophagy
GO:0015031--P:protein transport
KEGG pno:SNOG_06553
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001177 Aegilops tauschii 33.73 3.00e-08 47.80
IUUC-Aml-002116 Ailuropoda melanoleuca 26.56 7.00e-05 38.10
IUUC-Atr-002615 Amborella trichopoda 37.50 3.00e-08 47.80
IUUC-Aca-005231 Anolis carolinensis 26.56 1.40e-01 26.90
IUUC-Aly-006172 Arabidopsis lyrata 35.44 3.00e-09 51.20
IUUC-Ath-006953 Arabidopsis thaliana 38.46 6.00e-10 53.50
IUUC-Ago-007970 Ashbya gossypii 32.81 3.00e-05 39.70
IUUC-Acl-008072 Aspergillus clavatus 60.64 2.00e-30 122.00
IUUC-Afl-008725 Aspergillus flavus 59.81 1.00e-34 137.00
IUUC-Afu-008967 Aspergillus fumigatus 57.94 1.00e-33 134.00
IUUC-Ani-009248 Aspergillus nidulans 56.64 8.00e-34 134.00
IUUC-Ang-009684 Aspergillus niger 55.56 7.00e-33 131.00
IUUC-Aor-009947 Aspergillus oryzae 59.81 1.00e-34 137.00
IUUC-Ame-011656 Astyanax mexicanus 25.40 2.00e-04 35.80
IUUC-Bgr-012174 Blumeria graminis 40.43 6.00e-14 67.80
IUUC-Bta-012483 Bos taurus 28.12 2.00e-05 39.30
IUUC-Bci-013755 Botrytis cinerea 53.00 9.00e-22 93.60
IUUC-Bdi-014156 Brachypodium distachyon 34.38 3.00e-09 51.20
IUUC-Bol-015683 Brassica oleracea 36.84 3.00e-09 51.20
IUUC-Bra-016802 Brassica rapa 38.57 3.00e-08 47.80
IUUC-Cel-018242 Caenorhabditis elegans 34.72 2.00e-05 39.30
IUUC-Cja-019514 Callithrix jacchus 28.57 7.00e-05 38.50
IUUC-Cfa-020748 Canis familiaris 26.56 1.00e-04 37.70
IUUC-Cpo-021965 Cavia porcellus 26.56 7.00e-05 38.10
IUUC-Cre-023009 Chlamydomonas reinhardtii 40.35 3.00e-06 40.80
IUUC-Csa-023494 Chlorocebus sabaeus 28.12 2.00e-05 39.30
IUUC-Cho-024631 Choloepus hoffmanni 28.12 7.00e-05 38.50
IUUC-Cin-025609 Ciona intestinalis 34.38 4.00e-09 51.20
IUUC-Cgl-026722 Colletotrichum gloeosporioides 47.17 2.00e-25 105.00
IUUC-Dre-027479 Danio rerio 25.00 6.00e-05 37.70
IUUC-Dse-031440 Dothistroma septosporum 60.95 2.00e-34 135.00
IUUC-Dme-031892 Drosophila melanogaster 27.91 2.00e-06 42.70
IUUC-Ete-032550 Echinops telfairi 28.12 4.00e-05 38.10
IUUC-Eca-033553 Equus caballus 28.12 2.00e-05 39.70
IUUC-Fca-036524 Felis catus 26.56 4.00e-03 32.30
IUUC-Fal-036942 Ficedula albicollis 28.12 2.00e-05 38.90
IUUC-Fox-037753 Fusarium oxysporum 59.38 1.00e-27 114.00
IUUC-Gmo-039498 Gadus morhua 25.00 9.00e-05 37.00
IUUC-Ggr-039852 Gaeumannomyces graminis 55.56 6.00e-20 88.60
IUUC-Gga-041263 Gallus gallus 26.36 1.00e-04 37.40
IUUC-Gac-042346 Gasterosteus aculeatus 26.98 7.00e-05 37.40
IUUC-Gma-042896 Glycine max 36.62 3.00e-08 47.80
IUUC-Ggo-045601 Gorilla gorilla 28.12 5.00e-05 38.90
IUUC-Hsa-046903 Homo sapiens 28.12 2.00e-05 39.30
IUUC-Hvu-047239 Hordeum vulgare 35.96 4.00e-09 50.80
IUUC-Itr-048445 Ictidomys tridecemlineatus 28.12 4.00e-05 38.90
IUUC-Kpa-049355 Komagataella pastoris 34.71 5.00e-11 58.20
IUUC-Lch-050619 Latimeria chalumnae 31.25 5.00e-07 45.10
IUUC-Loc-052102 Lepisosteus oculatus 38.64 7.00e-05 36.60
IUUC-Lma-053299 Leptosphaeria maculans 74.77 9.00e-44 166.00
IUUC-Laf-054205 Loxodonta africana 28.12 2.00e-05 39.70
IUUC-Meu-056804 Macropus eugenii 26.56 3.00e-05 38.90
IUUC-Mor-057052 Magnaporthe oryzae 51.58 7.00e-21 91.30
IUUC-Mtr-057961 Medicago truncatula 36.36 4.00e-09 50.80
IUUC-Mla-059045 Melampsora laricipopulina 34.31 3.00e-14 68.20
IUUC-Mvi-060360 Microbotryum violaceum 41.27 8.00e-13 63.90
IUUC-Mmr-061654 Microcebus murinus 26.32 5.00e-06 41.20
IUUC-Mdo-062649 Monodelphis domestica 26.47 3.00e-06 42.40
IUUC-Mmu-064105 Mus musculus 28.12 3.00e-05 39.30
IUUC-Mac-065532 Musa acuminata 35.38 1.00e-08 49.30
IUUC-Mpu-066269 Mustela putorius furo 26.56 3.00e-05 39.30
IUUC-Mlu-067631 Myotis lucifugus 28.12 6.00e-05 38.10
IUUC-Nfi-068468 Neosartorya fischeri 60.64 2.00e-30 122.00
IUUC-Ncr-068750 Neurospora crassa 53.33 1.00e-26 110.00
IUUC-Nle-069483 Nomascus leucogenys 28.12 5.00e-05 38.90
IUUC-Opr-070936 Ochotona princeps 26.83 5.00e-05 38.90
IUUC-Obr-076322 Oryza brachyantha 35.38 9.00e-09 49.30
IUUC-Ogl-077226 Oryza glaberrima 38.98 2.00e-08 48.50
IUUC-Oin-079220 Oryza indica 33.33 3.00e-04 35.00
IUUC-Olo-080688 Oryza longistaminata 38.98 2.00e-08 48.50
IUUC-Ome-081265 Oryza meridionalis 38.98 2.00e-08 48.50
IUUC-Oru-084342 Oryza rufipogon 35.38 1.00e-07 48.10
IUUC-Osa-086212 Oryza sativa 38.98 2.00e-08 48.50
IUUC-Ola-087277 Oryzias latipes 24.71 5.00e-05 37.70
IUUC-Olu-087780 Ostreococcus lucimarinus 35.38 5.00e-06 40.40
IUUC-Oga-088175 Otolemur garnettii 28.12 2.00e-05 39.30
IUUC-Oar-089477 Ovis aries 28.12 6.00e-05 38.50
IUUC-Ptr-091129 Pan troglodytes 28.12 6.00e-05 38.50
IUUC-Psi-093351 Pelodiscus sinensis 27.63 3.00e-05 38.90
IUUC-Ppa-095788 Physcomitrella patens 36.84 9.00e-08 46.60
IUUC-Pfo-096993 Poecilia formosa 25.00 1.00e-04 37.00
IUUC-Pab-098502 Pongo abelii 28.12 6.00e-05 38.50
IUUC-Pop-098819 Populus trichocarpa 32.89 3.00e-08 47.80
IUUC-Ppe-101560 Prunus persica 35.38 1.00e-07 45.80
IUUC-Pva-102810 Pteropus vampyrus 28.12 4.00e-05 38.90
IUUC-Pgr-103531 Puccinia graminis 36.27 1.00e-14 69.70
IUUC-Ptt-103753 Puccinia triticina 35.71 8.00e-13 63.50
IUUC-Pyt-104733 Pyrenophora triticirepentis 76.86 7.00e-48 180.00
IUUC-Rno-106072 Rattus norvegicus 26.80 2.00e-06 42.70
IUUC-Sce-106275 Saccharomyces cerevisiae 38.57 9.00e-11 58.20
IUUC-Sha-107554 Sarcophilus harrisii 26.56 3.00e-05 39.30
IUUC-Sja-107682 Schizosaccharomyces japonicus 33.04 3.00e-18 82.00
IUUC-Spo-108275 Schizosaccharomyces pombe 43.08 2.00e-12 62.80
IUUC-Smo-109151 Selaginella moellendorffii 31.82 2.00e-08 48.10
IUUC-Sit-110270 Setaria italica 36.23 2.00e-08 48.50
IUUC-Sly-111862 Solanum lycopersicum 36.92 3.00e-08 47.80
IUUC-Sbi-114148 Sorghum bicolor 36.23 2.00e-08 48.50
IUUC-Sre-115216 Sporisorium reilianum 33.33 2.00e-10 56.20
IUUC-Ssc-116051 Sus scrofa 28.12 2.00e-05 39.70
IUUC-Tru-118466 Takifugu rubripes 27.87 5.00e-05 37.00
IUUC-Tni-119792 Tetraodon nigroviridis 27.87 1.00e-05 38.90
IUUC-Tca-121861 Theobroma cacao 31.87 6.00e-09 50.80
IUUC-Tvi-122499 Trichoderma virens 48.51 1.00e-22 96.70
IUUC-Tae-123431 Triticum aestivum 33.73 3.00e-08 47.80
IUUC-Tme-126934 Tuber melanosporum 51.19 1.00e-19 87.00
IUUC-Uma-129324 Ustilago maydis 33.33 9.00e-11 57.40
IUUC-Vda-129846 Verticillium dahliae 53.06 3.00e-25 105.00
IUUC-Vpa-130202 Vicugna pacos 50.00 4.70e-01 25.80
IUUC-Vvi-131474 Vitis vinifera 31.11 4.00e-08 48.50
IUUC-Xtr-132782 Xenopus tropicalis 26.56 2.00e-05 39.70
IUUC-Xma-134140 Xiphophorus maculatus 25.00 2.00e-04 36.20
IUUC-Yli-134517 Yarrowia lipolytica 47.83 6.00e-15 72.00
IUUC-Zma-134764 Zea mays 36.23 2.00e-08 48.50
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved