iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025587

UUCD1 version

UUC-CiI-00619

Ensembl Protein ID

ENSCINP00000013776.3

UniProt Accession

Q1RL25; F7A7Y1; Q1RL25_CIOIN

Genbank Protein ID

FAA00240.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

EAAA01002615

Gene Name

Ci-ZF(UBP)-3; zf(ubp)-3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000006716.3	ENSCINT00000013776.3	ENSCINP00000013776.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.30e-89	298.1	539	959

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle........kkkeklneenp....................................... 42
           tGl+NlgNtCY+NS++Q+L +++++r +ll         +         +                                       
   Q: 539  TGLRNLGNTCYLNSIIQVLGHLQKFRLCLLAlrdldgmdE-------H-Hdsltspvathsrmgrrstmemyenqtnvsrrmlrlqsgl 619
           7******************************744444331.......2.1355566777888888888999998999999999999999 PP
   S: 43   ....................kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkek 111
                                 p+ +l+++l++l + +w++k+k vsp ++l++++++ ++f+gy+qqDaqEfl+ lld++ +el+   
   Q: 620  ngghdgsassekdsvlpstqLPPSLSLCHELNDLYHIMWSGKWKLVSPCHFLSSVWQLIPSFRGYSQQDAQEFLCELLDKIVSELE--- 705
           9999999888888888777777777************************************************************2... PP
   S: 112  nkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.........slqdcL 191
                     ++++ +++ ++   ++ +++++ +F+g+l+s +kclec+n+ss+ epf+dlsl++p++ + +           +l+++L
   Q: 706  ---------WKRRRPQMMVSNGLATRISKVVHAVFEGKLHSMVKCLECGNISSTIEPFWDLSLEFPQRYHVNAYnwknsnqgcTLSEML 785
           .........334455667778999******************************************9997655599999********** PP
   S: 192  esftkeeelegenkyycekck.......................kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpl 257
           e+ft++e+l+g   y+c kc+                       k++eaek++k++klP++L +hLkRf++s + ++reki+  v+fp 
   Q: 786  EKFTEAEQLDGGCVYNCAKCNvteqqvtdrcnrrrrlssrkitqKLTEAEKQIKISKLPQILRFHLKRFRWSGR-NHREKITVPVNFPS 873
           *********************999999999999999999999988899***********************997.8889********** PP
   S: 258  eLdlspfctspeekqke.......kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           e+d++++c s+ +++ +       +  Y+L+avv+H+G +++sGHY+ay+ n+ gk W++++Ds+ + ++ ++v     ++aY+lfY +
   Q: 874  EFDIRQHCWSDHQSNVSapsssdgNFVYDLSAVVIHHGrGFGSGHYTAYCWNDIGKfWVHCNDSNLELCSIDDVMA---AQAYILFYSQ 959
           ********9955554447888888****************************99999*******************...********87 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MDKAKKSPDS KINCKTSEDT QILSKNDSSP SEVKNITKCT RFRLSREYEL RICNCKHILR 60
MTVGERHSVV NPQRWLCNVC FTTESVWACL SCPNVACGRY IHEHALNHYL ETQHPLAIDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCATGTATA TGTGCAGATG GTAACATGTT AACTTAGCTA GTTTTGAAGC TTGAACAAGC 60
GTACATACAC GCTGCACGTG TTTCTGTTTT CTTCAGCAAT CGTCAGCGCC GAAAAGGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cin:751572

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001220	Ailuropoda melanoleuca	48.75	7.00e-107	380.00
IUUC-Apl-003658	Anas platyrhynchos	47.70	9.00e-112	396.00
IUUC-Aca-004434	Anolis carolinensis	48.68	3.00e-115	408.00
IUUC-Aor-010035	Aspergillus oryzae	31.82	2.00e-30	124.00
IUUC-Ame-010986	Astyanax mexicanus	49.32	2.00e-111	394.00
IUUC-Bta-012774	Bos taurus	49.32	7.00e-109	386.00
IUUC-Cja-019171	Callithrix jacchus	49.10	4.00e-109	387.00
IUUC-Cfa-020957	Canis familiaris	49.54	3.00e-110	391.00
IUUC-Cpo-022233	Cavia porcellus	49.09	6.00e-109	386.00
IUUC-Csa-023177	Chlorocebus sabaeus	48.98	8.00e-109	386.00
IUUC-Cho-025051	Choloepus hoffmanni	49.52	8.00e-78	283.00
IUUC-Csv-025814	Ciona savignyi	80.46	0.00e+00	693.00
IUUC-Dre-027878	Danio rerio	49.32	6.00e-113	400.00
IUUC-Dno-029832	Dasypus novemcinctus	49.08	2.00e-107	382.00
IUUC-Ete-032627	Echinops telfairi	47.87	4.00e-110	390.00
IUUC-Eca-033863	Equus caballus	49.89	7.00e-112	396.00
IUUC-Eeu-035225	Erinaceus europaeus	45.64	2.00e-98	352.00
IUUC-Fca-036288	Felis catus	47.95	1.00e-105	376.00
IUUC-Fal-037207	Ficedula albicollis	48.16	1.00e-114	405.00
IUUC-Gmo-039249	Gadus morhua	52.13	1.00e-93	335.00
IUUC-Gga-040457	Gallus gallus	48.86	2.00e-113	401.00
IUUC-Gac-042595	Gasterosteus aculeatus	46.67	3.00e-104	371.00
IUUC-Ggo-044979	Gorilla gorilla	50.00	2.00e-110	391.00
IUUC-Hsa-046743	Homo sapiens	50.00	3.00e-110	391.00
IUUC-Itr-048251	Ictidomys tridecemlineatus	49.55	2.00e-111	395.00
IUUC-Lch-050294	Latimeria chalumnae	47.69	5.00e-111	393.00
IUUC-Loc-051981	Lepisosteus oculatus	48.99	3.00e-113	401.00
IUUC-Laf-054491	Loxodonta africana	48.17	7.00e-108	383.00
IUUC-Mcc-055048	Macaca mulatta	50.00	1.00e-110	392.00
IUUC-Meu-055971	Macropus eugenii	57.34	4.00e-45	174.00
IUUC-Mga-059523	Meleagris gallopavo	47.82	3.00e-114	404.00
IUUC-Mmr-060885	Microcebus murinus	48.33	7.00e-109	386.00
IUUC-Mdo-063018	Monodelphis domestica	47.57	2.00e-115	408.00
IUUC-Mmu-064095	Mus musculus	48.55	8.00e-111	392.00
IUUC-Mpu-066207	Mustela putorius furo	49.54	2.00e-109	389.00
IUUC-Mlu-067090	Myotis lucifugus	48.26	5.00e-111	394.00
IUUC-Nle-069486	Nomascus leucogenys	50.00	1.00e-110	392.00
IUUC-Opr-070563	Ochotona princeps	48.56	2.00e-109	388.00
IUUC-Ont-071637	Oreochromis niloticus	48.99	1.00e-111	395.00
IUUC-Oan-073245	Ornithorhynchus anatinus	52.27	1.00e-93	335.00
IUUC-Ocu-074836	Oryctolagus cuniculus	48.16	9.00e-110	389.00
IUUC-Ola-086413	Oryzias latipes	48.85	1.00e-109	388.00
IUUC-Olu-087697	Ostreococcus lucimarinus	30.23	8.00e-38	149.00
IUUC-Oga-088367	Otolemur garnettii	48.17	4.00e-105	374.00
IUUC-Oar-089953	Ovis aries	48.75	2.00e-110	391.00
IUUC-Ptr-090980	Pan troglodytes	50.00	5.00e-109	387.00
IUUC-Pan-092363	Papio anubis	50.00	4.00e-110	390.00
IUUC-Psi-093353	Pelodiscus sinensis	48.74	3.00e-113	401.00
IUUC-Pma-094293	Petromyzon marinus	48.11	9.00e-58	215.00
IUUC-Pfo-096860	Poecilia formosa	49.55	1.00e-111	395.00
IUUC-Pab-098514	Pongo abelii	49.31	8.00e-108	383.00
IUUC-Pca-100449	Procavia capensis	50.11	6.00e-107	380.00
IUUC-Pva-102868	Pteropus vampyrus	49.77	2.00e-109	388.00
IUUC-Rno-105190	Rattus norvegicus	48.77	7.00e-110	389.00
IUUC-Sha-107337	Sarcophilus harrisii	48.82	8.00e-112	396.00
IUUC-Sar-113561	Sorex araneus	58.27	4.00e-46	177.00
IUUC-Ssc-115735	Sus scrofa	49.20	2.00e-109	388.00
IUUC-Tgu-117160	Taeniopygia guttata	49.10	2.00e-114	405.00
IUUC-Tru-118156	Takifugu rubripes	47.71	3.00e-112	398.00
IUUC-Tsy-118814	Tarsius syrichta	48.97	1.00e-108	385.00
IUUC-Tni-120600	Tetraodon nigroviridis	48.87	5.00e-106	377.00
IUUC-Tbe-128084	Tupaia belangeri	50.00	4.00e-113	400.00
IUUC-Ttr-128928	Tursiops truncatus	48.39	1.00e-108	386.00
IUUC-Vda-129829	Verticillium dahliae	28.83	2.00e-25	108.00
IUUC-Vpa-130706	Vicugna pacos	48.17	1.00e-110	392.00
IUUC-Xtr-132090	Xenopus tropicalis	47.57	7.00e-112	396.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence