iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041749

UUCD1 version

UUC-GaA-01255

Ensembl Protein ID

ENSGACP00000014803.1

UniProt Accession

G3PB29; G3PB29_GASAC

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000011192.1	ENSGACT00000014831.1	ENSGACP00000014803.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-72	245.0	232	523

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 58   eelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlF 146
           +++++++++   p +ll+ +++ a+++ gyeqqDa+Efl   ld l++++k                  ++ ++ +++++ +++i+++F
   Q: 232  SQFYSGHRSPHIPFRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKG----------------DDNGKKANNPNHCNCIIDQIF 304
           455688888999**************************************22................22335677899999******* PP
   S: 147  qgqlksqikclecdnvssreepfldlslpvpgkeetkke....................slqdcLesftkeeelegenkyycekckkkq 215
            g l+s+++c+ c+ vs++ +pf+d+sl++pg+++   +                    +l+dcL+ ft++e+l ++ k++c  c+++q
   Q: 305  TGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPlspggdgstvngeshlsgstTLTDCLRRFTRPEHLGSSAKIKCGGCHSYQ 393
           **********************************87777************************************************** PP
   S: 216  eaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke............kkkYeLiavvvHsGslss 292
           e++k+l++kklP v ++hLkRf  +++ k r+ki+++v+fpleLd++pf++s++e+  +            ++kY+L+avv+H+G+l+s
   Q: 394  ESTKQLTMKKLPIVACFHLKRF--EHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNgqyqqtvdvlnnDNKYSLFAVVNHQGTLES 480
           **********************..5666899********************97777666899999999999****************** PP
   S: 293  GHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           GHY+++++++k++W+++dD  +t+ + ++vl    s++Y+lfY+++
   Q: 481  GHYTSFIRQHKDQWFKCDDAIITKASIKDVLD---SEGYLLFYHKQ 523
           ********************************...********985 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

FPLSPKKKKL KPNVLSVMSP AGCSHVNGYK VDNWKQNLRV IYQCFVWSGT AETRRRKQSW 60
SVCILCGMHI TALYSLLRCG SCNCSISNHK REGSETDRHN VLFLIMYRWI YCFVCQDYIY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCCATTGT CACCTAAAAA AAAAAAACTC AAACCGAATG TTTTGTCTGT CATGAGTCCG 60
GCCGGGTGCT CCCATGTGAA CGGTTATAAG GTGGACAATT GGAAACAAAA TCTTCGAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aor-010035	Aspergillus oryzae	35.36	5.00e-38	150.00
IUUC-Dor-030832	Dipodomys ordii	85.05	3.00e-96	345.00
IUUC-Eeu-034814	Erinaceus europaeus	94.76	3.00e-118	419.00
IUUC-Gmo-038474	Gadus morhua	98.31	2.00e-177	615.00
IUUC-Olo-080811	Oryza longistaminata	41.03	2.00e-51	195.00
IUUC-Pva-102409	Pteropus vampyrus	95.93	3.00e-173	601.00
IUUC-Sha-107538	Sarcophilus harrisii	93.55	2.00e-121	427.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence