iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013563

Ensembl Protein ID

ENSBTAP00000007976.3

UniProt Accession

Q1RMR3; Q1RMR3_BOVIN

Genbank Protein ID

AAI14762.1

Protein Name

Cortactin

Genbank Nucleotide ID

DAAA02063676

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000006071.4	ENSBTAT00000007976.3	ENSBTAP00000007976.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.50e-13	48.0	486	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 486  IALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--LCKGRYGLFPANYVE 535
           79***********************..9*********..9************97 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MWKASAGHTV SITPDDGGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE 60
NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCGCCTG GGAGCTGCGG GCGCGGCGGA GGCTGGGCAG TGCCGAGCCG GACCGGACCG 60
ACCCCAGGCG GCGGTGAGCG AGCTCGGCCT TCGCCGGGCG GGGGAGCGGG CCGGTTCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

KEGG

bta:506939

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	89.52	0.00e+00	899.00
IUUC-Apl-003745	Anas platyrhynchos	82.67	0.00e+00	763.00
IUUC-Aca-004438	Anolis carolinensis	78.61	0.00e+00	843.00
IUUC-Ame-011170	Astyanax mexicanus	46.51	2.00e-111	395.00
IUUC-Bgr-012041	Blumeria graminis	57.89	1.00e-15	78.60
IUUC-Cfa-020718	Canis familiaris	86.26	0.00e+00	894.00
IUUC-Cpo-022303	Cavia porcellus	86.18	0.00e+00	958.00
IUUC-Csa-023431	Chlorocebus sabaeus	88.36	0.00e+00	907.00
IUUC-Cin-025677	Ciona intestinalis	59.67	6.00e-117	414.00
IUUC-Csv-026140	Ciona savignyi	61.63	2.00e-107	382.00
IUUC-Dre-028012	Danio rerio	63.94	4.00e-176	611.00
IUUC-Dno-029332	Dasypus novemcinctus	79.64	0.00e+00	746.00
IUUC-Dme-031931	Drosophila melanogaster	55.76	2.00e-73	270.00
IUUC-Eca-033801	Equus caballus	90.33	0.00e+00	894.00
IUUC-Fca-035633	Felis catus	86.99	0.00e+00	734.00
IUUC-Fal-036775	Ficedula albicollis	82.31	0.00e+00	778.00
IUUC-Fox-037778	Fusarium oxysporum	59.65	1.00e-14	75.50
IUUC-Gmo-038507	Gadus morhua	61.97	1.00e-20	94.40
IUUC-Gga-040568	Gallus gallus	82.67	0.00e+00	793.00
IUUC-Gac-042253	Gasterosteus aculeatus	55.98	5.00e-115	408.00
IUUC-Hsa-046818	Homo sapiens	88.55	0.00e+00	907.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	85.43	0.00e+00	830.00
IUUC-Lch-050199	Latimeria chalumnae	69.72	5.00e-142	498.00
IUUC-Loc-052855	Lepisosteus oculatus	61.32	0.00e+00	629.00
IUUC-Lma-053035	Leptosphaeria maculans	59.18	3.00e-12	67.40
IUUC-Laf-053866	Loxodonta africana	88.18	0.00e+00	946.00
IUUC-Mcc-055515	Macaca mulatta	88.55	0.00e+00	885.00
IUUC-Mga-059791	Meleagris gallopavo	78.87	0.00e+00	786.00
IUUC-Mmr-061147	Microcebus murinus	88.04	0.00e+00	839.00
IUUC-Mdo-062660	Monodelphis domestica	60.43	6.00e-174	605.00
IUUC-Mmu-064023	Mus musculus	88.64	0.00e+00	907.00
IUUC-Mpu-065867	Mustela putorius furo	82.71	0.00e+00	772.00
IUUC-Mlu-067704	Myotis lucifugus	82.88	0.00e+00	760.00
IUUC-Ont-071873	Oreochromis niloticus	78.43	3.00e-163	568.00
IUUC-Oan-073528	Ornithorhynchus anatinus	80.55	5.00e-159	553.00
IUUC-Oga-088028	Otolemur garnettii	88.55	0.00e+00	896.00
IUUC-Oar-090203	Ovis aries	97.46	0.00e+00	879.00
IUUC-Pan-092594	Papio anubis	84.57	0.00e+00	828.00
IUUC-Psi-093389	Pelodiscus sinensis	81.59	0.00e+00	795.00
IUUC-Pma-094161	Petromyzon marinus	46.58	1.00e-83	304.00
IUUC-Pfo-097391	Poecilia formosa	54.87	5.00e-111	394.00
IUUC-Pab-097913	Pongo abelii	81.27	0.00e+00	778.00
IUUC-Rno-105489	Rattus norvegicus	88.46	0.00e+00	863.00
IUUC-Sha-107308	Sarcophilus harrisii	68.10	0.00e+00	652.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	2.00e-14	74.70
IUUC-Tgu-117049	Taeniopygia guttata	76.23	0.00e+00	711.00
IUUC-Tru-118718	Takifugu rubripes	74.93	3.00e-155	541.00
IUUC-Tni-120535	Tetraodon nigroviridis	59.52	9.00e-172	596.00
IUUC-Vda-129766	Verticillium dahliae	57.89	1.00e-13	72.00
IUUC-Xtr-131797	Xenopus tropicalis	65.74	0.00e+00	664.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence