iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088028

Ensembl Protein ID

ENSOGAP00000002001.2

UniProt Accession

H0WKB7; H0WKB7_OTOGA

Genbank Protein ID

ENSOGAP00000002001

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03144546

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000002239.2	ENSOGAT00000002243.2	ENSOGAP00000002001.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.00e-13	48.6	498	547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 498  IALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--VCKGRYGLFPANYVE 547
           79***********************..9*********..7************97 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MWKASAGHVV SITQDDGEAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE 60
NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGAAAG CTTCGGCAGG CCATGTGGTG TCCATCACCC AGGATGACGG GGAAGCTGAT 60
GACTGGGAGA CTGACCCGGA TTTTGTGGTA GGAGCTACCA GTCTTTTGCT TATTGTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	89.25	0.00e+00	926.00
IUUC-Apl-003745	Anas platyrhynchos	84.30	0.00e+00	788.00
IUUC-Aca-004438	Anolis carolinensis	80.57	0.00e+00	868.00
IUUC-Ame-011504	Astyanax mexicanus	55.52	2.00e-96	346.00
IUUC-Bgr-012041	Blumeria graminis	57.89	8.00e-16	79.00
IUUC-Bta-013563	Bos taurus	88.55	0.00e+00	877.00
IUUC-Bci-013690	Botrytis cinerea	58.82	5.00e-12	66.60
IUUC-Cfa-020718	Canis familiaris	86.03	0.00e+00	923.00
IUUC-Cpo-022303	Cavia porcellus	88.18	0.00e+00	986.00
IUUC-Csa-023431	Chlorocebus sabaeus	92.55	0.00e+00	958.00
IUUC-Cin-025677	Ciona intestinalis	61.33	9.00e-121	427.00
IUUC-Csv-026140	Ciona savignyi	65.00	3.00e-110	392.00
IUUC-Dre-028012	Danio rerio	57.91	3.00e-158	551.00
IUUC-Dno-029332	Dasypus novemcinctus	80.76	0.00e+00	775.00
IUUC-Dse-031182	Dothistroma septosporum	32.23	3.00e-10	60.50
IUUC-Dme-031931	Drosophila melanogaster	62.61	3.00e-74	272.00
IUUC-Eca-033801	Equus caballus	90.91	0.00e+00	931.00
IUUC-Fca-035633	Felis catus	87.12	0.00e+00	757.00
IUUC-Fal-036775	Ficedula albicollis	82.94	0.00e+00	796.00
IUUC-Fox-037778	Fusarium oxysporum	59.65	1.00e-14	75.10
IUUC-Gmo-038507	Gadus morhua	60.81	2.00e-20	94.00
IUUC-Gga-040568	Gallus gallus	84.12	0.00e+00	813.00
IUUC-Gac-042253	Gasterosteus aculeatus	56.64	1.00e-115	409.00
IUUC-Hsa-046818	Homo sapiens	92.55	0.00e+00	959.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	86.89	0.00e+00	871.00
IUUC-Lch-050199	Latimeria chalumnae	71.67	2.00e-146	512.00
IUUC-Loc-052855	Lepisosteus oculatus	76.19	6.00e-154	537.00
IUUC-Laf-053866	Loxodonta africana	90.04	0.00e+00	970.00
IUUC-Mcc-055515	Macaca mulatta	92.18	0.00e+00	934.00
IUUC-Mga-059791	Meleagris gallopavo	84.00	0.00e+00	812.00
IUUC-Mmr-061147	Microcebus murinus	92.39	0.00e+00	890.00
IUUC-Mdo-062660	Monodelphis domestica	62.03	2.00e-173	603.00
IUUC-Mmu-064023	Mus musculus	90.00	0.00e+00	927.00
IUUC-Mpu-065867	Mustela putorius furo	77.60	0.00e+00	791.00
IUUC-Mlu-067704	Myotis lucifugus	82.58	0.00e+00	788.00
IUUC-Ont-071873	Oreochromis niloticus	80.67	4.00e-168	584.00
IUUC-Oan-073528	Ornithorhynchus anatinus	82.79	2.00e-164	571.00
IUUC-Oar-090203	Ovis aries	87.95	0.00e+00	811.00
IUUC-Pan-092594	Papio anubis	88.02	0.00e+00	874.00
IUUC-Psi-093389	Pelodiscus sinensis	82.30	0.00e+00	810.00
IUUC-Pma-094161	Petromyzon marinus	46.30	1.00e-83	303.00
IUUC-Pno-095096	Phaeosphaeria nodorum	58.18	1.00e-13	72.00
IUUC-Pfo-097391	Poecilia formosa	54.87	1.00e-111	397.00
IUUC-Pab-097913	Pongo abelii	85.09	0.00e+00	829.00
IUUC-Rno-105489	Rattus norvegicus	89.64	0.00e+00	880.00
IUUC-Sce-106228	Saccharomyces cerevisiae	50.00	8.00e-07	48.90
IUUC-Sha-107308	Sarcophilus harrisii	69.06	0.00e+00	674.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	1.00e-14	75.10
IUUC-Tgu-117049	Taeniopygia guttata	76.73	0.00e+00	723.00
IUUC-Tru-118718	Takifugu rubripes	76.54	2.00e-159	555.00
IUUC-Tni-120535	Tetraodon nigroviridis	58.71	1.00e-168	586.00
IUUC-Tme-127196	Tuber melanosporum	59.65	8.00e-15	75.90
IUUC-Vda-129766	Verticillium dahliae	57.89	2.00e-13	71.60
IUUC-Xtr-131797	Xenopus tropicalis	65.64	0.00e+00	659.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence