iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097913

Ensembl Protein ID

ENSPPYP00000003425.1

UniProt Accession

H2NCJ1; H2NCJ1_PONAB

Genbank Protein ID

ENSPPYP00000003425

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01352559

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000002954.2	ENSPPYT00000003548.1	ENSPPYP00000003425.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.20e-13	48.2	456	505

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 456  VALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--VCKGRYGLFPANYVE 505
           69***********************..9*********..7************97 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MWKASAGHAV SIAQDDAGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE 60
NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACGGAATCA TTCCCCAATG CCTGGAAATT CCTCATTGGA TTACTGTGTT TTAAACAGAG 60
TTTTGTGAGC ACCCTTTTAT CTCCAAGCGG AAAGAAAGGT ACTTATGCAT TGTGAACATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	82.15	0.00e+00	819.00
IUUC-Apl-003745	Anas platyrhynchos	77.94	0.00e+00	698.00
IUUC-Aca-004438	Anolis carolinensis	73.62	0.00e+00	761.00
IUUC-Ame-011504	Astyanax mexicanus	61.23	4.00e-98	351.00
IUUC-Bgr-012041	Blumeria graminis	57.89	6.00e-16	79.30
IUUC-Bta-013563	Bos taurus	80.18	0.00e+00	768.00
IUUC-Bci-013690	Botrytis cinerea	58.82	5.00e-12	66.60
IUUC-Cfa-020718	Canis familiaris	78.40	0.00e+00	809.00
IUUC-Cpo-022303	Cavia porcellus	80.91	0.00e+00	892.00
IUUC-Csa-023431	Chlorocebus sabaeus	89.27	0.00e+00	901.00
IUUC-Cin-025677	Ciona intestinalis	56.10	1.00e-99	357.00
IUUC-Csv-026140	Ciona savignyi	65.27	5.00e-95	341.00
IUUC-Dre-028012	Danio rerio	68.62	0.00e+00	630.00
IUUC-Dno-029332	Dasypus novemcinctus	86.96	0.00e+00	774.00
IUUC-Dme-031931	Drosophila melanogaster	49.04	2.00e-82	299.00
IUUC-Eca-033801	Equus caballus	84.52	0.00e+00	827.00
IUUC-Fca-035633	Felis catus	80.68	0.00e+00	659.00
IUUC-Fal-036775	Ficedula albicollis	75.81	0.00e+00	695.00
IUUC-Gmo-038507	Gadus morhua	60.00	1.00e-20	94.70
IUUC-Gga-040568	Gallus gallus	77.08	0.00e+00	712.00
IUUC-Gac-042253	Gasterosteus aculeatus	56.86	6.00e-111	394.00
IUUC-Hsa-046818	Homo sapiens	90.00	0.00e+00	908.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	81.93	0.00e+00	787.00
IUUC-Lch-050199	Latimeria chalumnae	60.28	3.00e-114	405.00
IUUC-Loc-052855	Lepisosteus oculatus	82.81	4.00e-154	538.00
IUUC-Laf-053866	Loxodonta africana	82.07	0.00e+00	864.00
IUUC-Mcc-055515	Macaca mulatta	89.64	0.00e+00	871.00
IUUC-Mga-059791	Meleagris gallopavo	72.73	0.00e+00	706.00
IUUC-Mmr-061147	Microcebus murinus	85.14	0.00e+00	776.00
IUUC-Mdo-062660	Monodelphis domestica	65.08	3.00e-180	626.00
IUUC-Mmu-064023	Mus musculus	84.36	0.00e+00	842.00
IUUC-Mpu-065867	Mustela putorius furo	87.30	0.00e+00	800.00
IUUC-Mlu-067704	Myotis lucifugus	82.40	0.00e+00	768.00
IUUC-Ont-071873	Oreochromis niloticus	71.15	3.00e-140	491.00
IUUC-Oan-073528	Ornithorhynchus anatinus	73.07	1.00e-138	485.00
IUUC-Oga-088028	Otolemur garnettii	84.00	0.00e+00	840.00
IUUC-Oar-090203	Ovis aries	80.11	0.00e+00	701.00
IUUC-Pan-092594	Papio anubis	89.66	0.00e+00	867.00
IUUC-Psi-093389	Pelodiscus sinensis	75.58	0.00e+00	705.00
IUUC-Pma-094161	Petromyzon marinus	45.83	7.00e-81	294.00
IUUC-Pfo-097391	Poecilia formosa	59.01	3.00e-111	395.00
IUUC-Rno-105489	Rattus norvegicus	83.09	0.00e+00	779.00
IUUC-Sce-106228	Saccharomyces cerevisiae	50.00	7.00e-07	48.90
IUUC-Sha-107308	Sarcophilus harrisii	74.95	0.00e+00	695.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	1.00e-14	75.10
IUUC-Tgu-117049	Taeniopygia guttata	82.07	0.00e+00	733.00
IUUC-Tru-118718	Takifugu rubripes	70.11	2.00e-142	499.00
IUUC-Tni-120535	Tetraodon nigroviridis	57.76	1.00e-170	592.00
IUUC-Vda-129766	Verticillium dahliae	57.89	1.00e-13	72.00
IUUC-Xtr-131797	Xenopus tropicalis	59.90	3.00e-165	575.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence