iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022126

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02016539

Gene Name

BTRC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000005488.3	ENSCPOT00000005547.2	ENSCPOP00000004942.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-55	181.0	491	522
UBD/Beta-Prp	1.50e-63	214.7	405	569

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrt 32
           gH++ v+c++f d +++vsG++Dg+ikvWDl  
   Q: 491  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLLA 522
           8**********.44****************865 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ +
   Q: 405  LRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR-V 488
           445579*************9..8**************************************..************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           l+gh+++v+c++++   + +vsG++D+++++Wdl         +   +lrtl + h ++v  l+fd+  +++vs s+d t+ +wd+
   Q: 489  LEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLlaaldprapAGTLCLRTLVE-HSGRVFRLQFDE--FQIVSSSHDDTILIWDF 569
           **************9..*************************877889****98.************..99**************7 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

VLSLQCSMPR SLWLGCSSLA DSMPSLRCLC HPGTGALTAF QNSSEREDCN NDEPPRKIIP 60
EKNSLRQTYN SCARLCLNQE TVCLASTAMK TENCVAKTKL ANGTSSMIVS KQRKLSASYE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCTCTCTC TGCAGTGCTC TATGCCCAGG TCTCTGTGGC TGGGCTGCTC CAGCCTGGCG 60
GACAGCATGC CTTCGCTGCG ATGCCTGTGT CACCCAGGGA CTGGCGCACT CACAGCTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0071407--P:cellular response to organic cyclic compound
GO:0033598--P:mammary gland epithelial cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0060828--P:regulation of canonical Wnt signaling pathway
GO:0051726--P:regulation of cell cycle
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061136--P:regulation of proteasomal protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001961	Ailuropoda melanoleuca	96.97	0.00e+00	1195.00
IUUC-Apl-003437	Anas platyrhynchos	96.59	0.00e+00	995.00
IUUC-Aca-004410	Anolis carolinensis	94.58	0.00e+00	1162.00
IUUC-Acl-008160	Aspergillus clavatus	35.08	1.00e-43	172.00
IUUC-Afl-008678	Aspergillus flavus	34.42	1.00e-40	161.00
IUUC-Aor-010185	Aspergillus oryzae	29.58	2.00e-48	186.00
IUUC-Ate-010546	Aspergillus terreus	37.28	6.00e-43	169.00
IUUC-Bgr-012194	Blumeria graminis	32.30	1.00e-51	197.00
IUUC-Bta-013453	Bos taurus	97.66	0.00e+00	1127.00
IUUC-Cja-019121	Callithrix jacchus	92.76	0.00e+00	1129.00
IUUC-Cfa-020553	Canis familiaris	97.14	0.00e+00	1196.00
IUUC-Csa-023688	Chlorocebus sabaeus	97.14	0.00e+00	1195.00
IUUC-Dno-029484	Dasypus novemcinctus	91.57	0.00e+00	1132.00
IUUC-Dor-031010	Dipodomys ordii	90.07	0.00e+00	1040.00
IUUC-Ete-032978	Echinops telfairi	83.97	0.00e+00	993.00
IUUC-Eca-033374	Equus caballus	97.30	0.00e+00	1194.00
IUUC-Eeu-034760	Erinaceus europaeus	75.59	0.00e+00	886.00
IUUC-Fca-035427	Felis catus	92.93	0.00e+00	1130.00
IUUC-Fal-037530	Ficedula albicollis	96.78	0.00e+00	1182.00
IUUC-Gga-041087	Gallus gallus	96.78	0.00e+00	1183.00
IUUC-Ggo-045369	Gorilla gorilla	97.65	0.00e+00	1120.00
IUUC-Hsa-045962	Homo sapiens	97.14	0.00e+00	1195.00
IUUC-Itr-047872	Ictidomys tridecemlineatus	97.57	0.00e+00	914.00
IUUC-Lch-050285	Latimeria chalumnae	88.58	0.00e+00	918.00
IUUC-Loc-052686	Lepisosteus oculatus	90.57	0.00e+00	1120.00
IUUC-Laf-054022	Loxodonta africana	97.30	0.00e+00	1195.00
IUUC-Mcc-055782	Macaca mulatta	97.79	0.00e+00	1189.00
IUUC-Meu-056078	Macropus eugenii	83.08	0.00e+00	875.00
IUUC-Mga-059388	Meleagris gallopavo	96.29	0.00e+00	1182.00
IUUC-Mmr-060969	Microcebus murinus	97.14	0.00e+00	1196.00
IUUC-Mdo-063041	Monodelphis domestica	96.96	0.00e+00	1162.00
IUUC-Mmu-064096	Mus musculus	96.13	0.00e+00	1186.00
IUUC-Mpu-066875	Mustela putorius furo	96.68	0.00e+00	1084.00
IUUC-Mlu-067621	Myotis lucifugus	97.22	0.00e+00	1011.00
IUUC-Nle-069548	Nomascus leucogenys	96.97	0.00e+00	1194.00
IUUC-Opr-071194	Ochotona princeps	91.08	0.00e+00	1101.00
IUUC-Oan-072867	Ornithorhynchus anatinus	93.30	0.00e+00	1172.00
IUUC-Ocu-074246	Oryctolagus cuniculus	97.14	0.00e+00	1196.00
IUUC-Oga-088244	Otolemur garnettii	97.79	0.00e+00	1012.00
IUUC-Oar-089199	Ovis aries	97.24	0.00e+00	1021.00
IUUC-Pan-092826	Papio anubis	97.14	0.00e+00	1195.00
IUUC-Psi-093485	Pelodiscus sinensis	94.44	0.00e+00	1152.00
IUUC-Pma-094315	Petromyzon marinus	80.58	0.00e+00	893.00
IUUC-Pab-097680	Pongo abelii	96.63	0.00e+00	1190.00
IUUC-Pca-100843	Procavia capensis	90.22	0.00e+00	1071.00
IUUC-Pva-102793	Pteropus vampyrus	86.53	0.00e+00	1031.00
IUUC-Rno-105304	Rattus norvegicus	96.59	0.00e+00	1178.00
IUUC-Sha-107454	Sarcophilus harrisii	92.30	0.00e+00	1145.00
IUUC-Sar-113471	Sorex araneus	75.59	0.00e+00	864.00
IUUC-Ssc-115490	Sus scrofa	98.02	0.00e+00	1029.00
IUUC-Tgu-117445	Taeniopygia guttata	95.96	0.00e+00	1182.00
IUUC-Tsy-118983	Tarsius syrichta	93.55	0.00e+00	1130.00
IUUC-Tbe-128146	Tupaia belangeri	87.37	0.00e+00	1008.00
IUUC-Ttr-128946	Tursiops truncatus	96.97	0.00e+00	1196.00
IUUC-Vda-129941	Verticillium dahliae	32.37	8.00e-54	205.00
IUUC-Vpa-130709	Vicugna pacos	95.12	0.00e+00	1163.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence