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Tag Content
UUCD2 ID IUUC-Bta-012744
UUCD1 version UUC-BoT-00802
Ensembl Protein ID ENSBTAP00000002293.3
UniProt Accession Q5BIM1; TRI45_BOVIN
Genbank Protein ID AAX31385.1
Protein Name Tripartite motif-containing protein 45
Genbank Nucleotide ID BT021203
Gene Name TRIM45
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000001748.3 ENSBTAT00000002293.3 ENSBTAP00000002293.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 1.00e-07 32.5 29 97
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw.........................pglknssskefrCPlC 45
           C++C+  fk  p++lpC H+ +++Cl+++                         + +  + +  ++CP+C
   Q: 29   CPLCMGLFKA-PRLLPCLHTVCTTCLEQLepfsvvdirggesdtssegsvfqelKPRALQPQIGILCPVC 97
           ********99.***************9999999999988888777777777744333333344446**** PP
   
Organism Bos taurus
Functional Description
(View)

Functional Description


     May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.
 May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.
Protein Sequence
(Fasta)
MAEKRRPLLG FVGKLPSGTT AGNSGKTHCP LCMGLFKAPR LLPCLHTVCT TCLEQLEPFS 60
VVDIRGGESD TSSEGSVFQE LKPRALQPQI GILCPVCDAQ VDLPMGGVKA LTIDHLAMND 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-012744|E3,RING|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATTGGAGTCG TCTGAGTAGC CCCGGGATTG GTGCGAGGCG GGGCCAGAGC CGTCGGGCAC 60
CTTGGACCGA AGGGTGGGGA GGTGGTGGCA ACCGAGGAGC CGGTGGGGGC TCGCAGCTCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-012744|E3,RING|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003649--Bbox_C
IPR017868--Filamin/ABP280_repeat-like
IPR001298--Filamin/ABP280_rpt
IPR013783--Ig-like_fold
IPR014756--Ig_E-set
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50194--FILAMIN_REPEAT
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00630--Filamin
PF00643--zf-B_box
PF13445--zf-RING_UBOX
SMART

SM00502--BBC
SM00336--BBOX
SM00557--IG_FLMN
SM00184--RING
Gene Ontology

GO:0005829--C:cytosol
GO:0045171--C:intercellular bridge
GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0060348--P:bone development
KEGG bta:539091
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002020 Ailuropoda melanoleuca 92.59 0.00e+00 1041.00
IUUC-Ame-010865 Astyanax mexicanus 46.43 5.00e-128 451.00
IUUC-Cel-018225 Caenorhabditis elegans 24.22 6.00e-20 93.20
IUUC-Cja-019162 Callithrix jacchus 87.24 0.00e+00 982.00
IUUC-Cfa-020163 Canis familiaris 91.21 0.00e+00 1026.00
IUUC-Csa-023746 Chlorocebus sabaeus 89.48 0.00e+00 1013.00
IUUC-Cho-024414 Choloepus hoffmanni 78.89 0.00e+00 766.00
IUUC-Dre-028598 Danio rerio 47.83 2.00e-117 416.00
IUUC-Dno-029616 Dasypus novemcinctus 88.91 0.00e+00 994.00
IUUC-Dor-030216 Dipodomys ordii 80.24 5.00e-64 238.00
IUUC-Dme-031817 Drosophila melanogaster 28.32 7.00e-64 239.00
IUUC-Ete-032434 Echinops telfairi 85.15 0.00e+00 894.00
IUUC-Eca-034410 Equus caballus 89.83 0.00e+00 1019.00
IUUC-Eeu-034954 Erinaceus europaeus 88.47 0.00e+00 998.00
IUUC-Fca-035410 Felis catus 91.38 0.00e+00 1026.00
IUUC-Fox-038002 Fusarium oxysporum 29.89 2.50e-02 32.70
IUUC-Gmo-039232 Gadus morhua 47.87 5.00e-131 461.00
IUUC-Gac-042350 Gasterosteus aculeatus 44.82 1.00e-105 377.00
IUUC-Ggo-045080 Gorilla gorilla 89.14 0.00e+00 1012.00
IUUC-Hsa-046580 Homo sapiens 88.97 0.00e+00 1006.00
IUUC-Itr-048145 Ictidomys tridecemlineatus 86.90 0.00e+00 974.00
IUUC-Lch-049464 Latimeria chalumnae 57.86 0.00e+00 647.00
IUUC-Loc-052772 Lepisosteus oculatus 51.16 6.00e-70 258.00
IUUC-Mcc-055349 Macaca mulatta 87.76 0.00e+00 983.00
IUUC-Meu-056674 Macropus eugenii 65.34 0.00e+00 741.00
IUUC-Mmr-061225 Microcebus murinus 88.23 0.00e+00 986.00
IUUC-Mdo-062597 Monodelphis domestica 62.87 0.00e+00 687.00
IUUC-Mmu-063099 Mus musculus 85.00 0.00e+00 962.00
IUUC-Mlu-067034 Myotis lucifugus 89.14 0.00e+00 995.00
IUUC-Nle-069855 Nomascus leucogenys 89.48 0.00e+00 1043.00
IUUC-Opr-070954 Ochotona princeps 87.95 0.00e+00 970.00
IUUC-Ont-071292 Oreochromis niloticus 48.77 2.00e-130 459.00
IUUC-Oga-087909 Otolemur garnettii 87.59 0.00e+00 993.00
IUUC-Oar-089619 Ovis aries 97.76 0.00e+00 1094.00
IUUC-Ptr-090712 Pan troglodytes 88.79 0.00e+00 1006.00
IUUC-Pan-092806 Papio anubis 89.14 0.00e+00 1008.00
IUUC-Psi-093414 Pelodiscus sinensis 63.39 0.00e+00 716.00
IUUC-Pfo-096848 Poecilia formosa 45.75 7.00e-129 454.00
IUUC-Pab-098353 Pongo abelii 87.59 0.00e+00 1007.00
IUUC-Pca-100183 Procavia capensis 86.40 0.00e+00 973.00
IUUC-Pva-102140 Pteropus vampyrus 88.79 0.00e+00 1007.00
IUUC-Rno-105886 Rattus norvegicus 84.66 0.00e+00 952.00
IUUC-Sha-107458 Sarcophilus harrisii 64.89 0.00e+00 690.00
IUUC-Sly-111723 Solanum lycopersicum 36.05 7.00e-06 46.20
IUUC-Sar-112944 Sorex araneus 68.28 0.00e+00 687.00
IUUC-Ssc-116231 Sus scrofa 91.90 0.00e+00 1038.00
IUUC-Tgu-116859 Taeniopygia guttata 57.50 2.00e-159 555.00
IUUC-Tru-118209 Takifugu rubripes 48.39 1.00e-130 460.00
IUUC-Tni-120290 Tetraodon nigroviridis 48.17 1.00e-118 420.00
IUUC-Tvi-122468 Trichoderma virens 25.71 3.60e-02 34.70
IUUC-Tbe-128111 Tupaia belangeri 89.57 0.00e+00 869.00
IUUC-Ttr-128584 Tursiops truncatus 90.86 0.00e+00 982.00
IUUC-Vvi-131620 Vitis vinifera 32.00 5.00e-06 43.90
IUUC-Xtr-132137 Xenopus tropicalis 43.28 2.00e-107 382.00
IUUC-Xma-134298 Xiphophorus maculatus 47.31 2.00e-131 462.00
Created Date 25-Jun-2017

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