iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034411

UUCD1 version

UUC-EqC-00480

Ensembl Protein ID

ENSECAP00000007291.1

UniProt Accession

F6XV77; F6XV77_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000008960.1	ENSECAT00000009561.1	ENSECAP00000007291.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.80e-113	378.9	703	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 703  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 787
           7899********************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di++lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 788  EGIVVDVPFASFFLSQLLGHhhsvfYSSVDELPSLDSEFYKNLTSIKRY-DGDISDLGLTLSY--DEDVMGQLVCHELVPGGKTIPV 871
           ********************777777999********************.7799998777776..5999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++a+ +Gf+++i++e+ ++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 872  TNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWTRMFSTPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 958
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ +er++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+Y
   Q: 959  ILaSDFTPDERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPNY 1045
           **99*************************************************************8888****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k++l+ekL+yAi++++gFels
   Q: 1046 SKKSVLREKLRYAISMNTGFELS 1068
           ********************985 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MFTVSQTSRA WFIDRARQAR EERLVQKERE RAAVGIQAHV RSFLCRRRLR REIRREIDEF 60
FTADDSGSSK RSALCIFKIA RKLLFLFRIK EDNERFEKLC RCILSSMDAE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAAGATGG CGGTCGGGCC TCGGCCGCTG CCCCGGGTCT GGCAGAGCTT GGGGGTATTA 60
GGCTGAGGCT GCGGTGGCTG TGGCGCCAAC CCCGTGCGCG GGGGCCTCGA ACAGGTAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ecb:100059725

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	36.38	5.00e-107	382.00
IUUC-Aml-002107	Ailuropoda melanoleuca	97.57	0.00e+00	2088.00
IUUC-Atr-003017	Amborella trichopoda	38.48	2.00e-110	394.00
IUUC-Apl-003328	Anas platyrhynchos	90.33	0.00e+00	1858.00
IUUC-Aly-005794	Arabidopsis lyrata	39.11	6.00e-110	392.00
IUUC-Ath-007269	Arabidopsis thaliana	39.46	1.00e-112	400.00
IUUC-Bta-013547	Bos taurus	97.00	0.00e+00	2121.00
IUUC-Bdi-014502	Brachypodium distachyon	39.15	2.00e-110	394.00
IUUC-Bol-015093	Brassica oleracea	40.18	9.00e-114	405.00
IUUC-Bra-016722	Brassica rapa	40.18	1.00e-114	407.00
IUUC-Cel-018447	Caenorhabditis elegans	38.48	0.00e+00	676.00
IUUC-Cja-019855	Callithrix jacchus	97.00	0.00e+00	2073.00
IUUC-Cfa-020066	Canis familiaris	97.16	0.00e+00	2064.00
IUUC-Cpo-021504	Cavia porcellus	95.13	0.00e+00	2056.00
IUUC-Csa-023579	Chlorocebus sabaeus	96.82	0.00e+00	2075.00
IUUC-Cho-024430	Choloepus hoffmanni	86.32	0.00e+00	1556.00
IUUC-Cin-025750	Ciona intestinalis	47.25	0.00e+00	961.00
IUUC-Csv-026016	Ciona savignyi	48.13	0.00e+00	1009.00
IUUC-Dre-028271	Danio rerio	81.87	0.00e+00	1748.00
IUUC-Dno-029054	Dasypus novemcinctus	97.38	0.00e+00	2083.00
IUUC-Dor-030938	Dipodomys ordii	88.11	0.00e+00	1853.00
IUUC-Dme-031602	Drosophila melanogaster	48.15	0.00e+00	957.00
IUUC-Ete-033041	Echinops telfairi	76.82	0.00e+00	1355.00
IUUC-Eeu-035201	Erinaceus europaeus	85.34	0.00e+00	810.00
IUUC-Fca-036594	Felis catus	95.97	0.00e+00	2058.00
IUUC-Fal-037317	Ficedula albicollis	85.29	0.00e+00	1857.00
IUUC-Gmo-039412	Gadus morhua	77.84	0.00e+00	1712.00
IUUC-Gga-040149	Gallus gallus	88.97	0.00e+00	1883.00
IUUC-Gac-042088	Gasterosteus aculeatus	80.86	0.00e+00	1804.00
IUUC-Gma-042728	Glycine max	40.85	6.00e-112	399.00
IUUC-Ggo-045279	Gorilla gorilla	96.91	0.00e+00	2072.00
IUUC-Hsa-045660	Homo sapiens	96.72	0.00e+00	2068.00
IUUC-Hvu-047102	Hordeum vulgare	36.23	7.00e-107	382.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	94.83	0.00e+00	1041.00
IUUC-Lch-050664	Latimeria chalumnae	82.82	0.00e+00	1814.00
IUUC-Lpe-050755	Leersia perrieri	37.28	5.00e-99	355.00
IUUC-Loc-052791	Lepisosteus oculatus	83.61	0.00e+00	1784.00
IUUC-Laf-053902	Loxodonta africana	97.19	0.00e+00	2085.00
IUUC-Mcc-054730	Macaca mulatta	96.72	0.00e+00	2074.00
IUUC-Meu-056527	Macropus eugenii	80.13	0.00e+00	1662.00
IUUC-Mtr-057671	Medicago truncatula	39.96	2.00e-112	400.00
IUUC-Mga-059260	Meleagris gallopavo	88.53	0.00e+00	1878.00
IUUC-Mmr-060804	Microcebus murinus	94.95	0.00e+00	2013.00
IUUC-Mdo-062575	Monodelphis domestica	84.22	0.00e+00	1774.00
IUUC-Mmu-063636	Mus musculus	92.52	0.00e+00	1931.00
IUUC-Mac-064989	Musa acuminata	39.54	5.00e-108	385.00
IUUC-Mpu-066677	Mustela putorius furo	97.21	0.00e+00	1956.00
IUUC-Mlu-067952	Myotis lucifugus	96.82	0.00e+00	2028.00
IUUC-Nle-069153	Nomascus leucogenys	96.72	0.00e+00	2068.00
IUUC-Opr-070554	Ochotona princeps	94.59	0.00e+00	1877.00
IUUC-Ont-071372	Oreochromis niloticus	82.04	0.00e+00	1783.00
IUUC-Oan-073327	Ornithorhynchus anatinus	72.35	0.00e+00	750.00
IUUC-Ocu-074183	Oryctolagus cuniculus	95.14	0.00e+00	2022.00
IUUC-Oba-075213	Oryza barthii	38.82	6.00e-107	382.00
IUUC-Obr-076320	Oryza brachyantha	35.24	1.00e-110	394.00
IUUC-Ogl-077093	Oryza glaberrima	39.09	1.00e-109	391.00
IUUC-Ogu-078947	Oryza glumaepatula	36.81	2.00e-109	390.00
IUUC-Oin-080058	Oryza indica	39.09	1.00e-109	390.00
IUUC-Olo-080742	Oryza longistaminata	38.82	2.00e-108	387.00
IUUC-Ome-081741	Oryza meridionalis	38.64	3.00e-102	366.00
IUUC-Oni-082385	Oryza nivara	36.81	2.00e-109	390.00
IUUC-Opu-083529	Oryza punctata	38.99	2.00e-109	390.00
IUUC-Oru-085128	Oryza rufipogon	36.69	4.00e-96	346.00
IUUC-Osa-085557	Oryza sativa	39.09	4.00e-109	389.00
IUUC-Ola-087337	Oryzias latipes	81.10	0.00e+00	1717.00
IUUC-Oga-088342	Otolemur garnettii	95.98	0.00e+00	1988.00
IUUC-Oar-090234	Ovis aries	96.59	0.00e+00	2091.00
IUUC-Ptr-091661	Pan troglodytes	96.91	0.00e+00	2071.00
IUUC-Pan-092728	Papio anubis	96.54	0.00e+00	2068.00
IUUC-Psi-093251	Pelodiscus sinensis	88.38	0.00e+00	1739.00
IUUC-Pma-094195	Petromyzon marinus	70.20	0.00e+00	1441.00
IUUC-Ppa-095867	Physcomitrella patens	39.43	2.00e-110	394.00
IUUC-Pfo-097472	Poecilia formosa	81.48	0.00e+00	1788.00
IUUC-Pab-098570	Pongo abelii	96.72	0.00e+00	2068.00
IUUC-Pca-100110	Procavia capensis	84.36	0.00e+00	1756.00
IUUC-Ppe-101281	Prunus persica	39.01	9.00e-108	385.00
IUUC-Pva-102887	Pteropus vampyrus	92.33	0.00e+00	1943.00
IUUC-Rno-106028	Rattus norvegicus	89.36	0.00e+00	1833.00
IUUC-Sha-107331	Sarcophilus harrisii	85.63	0.00e+00	1803.00
IUUC-Smo-109537	Selaginella moellendorffii	37.32	8.00e-106	378.00
IUUC-Sit-109811	Setaria italica	35.75	1.00e-111	397.00
IUUC-Sly-111013	Solanum lycopersicum	39.03	6.00e-103	369.00
IUUC-Sar-113287	Sorex araneus	87.82	0.00e+00	731.00
IUUC-Sbi-114433	Sorghum bicolor	35.52	2.00e-111	397.00
IUUC-Ssc-116103	Sus scrofa	97.57	0.00e+00	2084.00
IUUC-Tgu-117275	Taeniopygia guttata	88.41	0.00e+00	1862.00
IUUC-Tru-118681	Takifugu rubripes	80.64	0.00e+00	1800.00
IUUC-Tsy-118985	Tarsius syrichta	92.59	0.00e+00	1023.00
IUUC-Tni-120850	Tetraodon nigroviridis	90.98	0.00e+00	771.00
IUUC-Tca-121770	Theobroma cacao	39.18	3.00e-112	399.00
IUUC-Tae-125466	Triticum aestivum	36.51	4.00e-107	382.00
IUUC-Tur-126086	Triticum urartu	39.61	6.00e-106	379.00
IUUC-Tbe-127461	Tupaia belangeri	91.85	0.00e+00	1910.00
IUUC-Ttr-129269	Tursiops truncatus	96.82	0.00e+00	2065.00
IUUC-Vpa-130523	Vicugna pacos	79.23	7.00e-132	464.00
IUUC-Vvi-131524	Vitis vinifera	39.04	2.00e-109	390.00
IUUC-Xtr-132146	Xenopus tropicalis	84.14	0.00e+00	1828.00
IUUC-Xma-133526	Xiphophorus maculatus	81.20	0.00e+00	1783.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence