iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000000632.1	ENSFALT00000000658.1	ENSFALP00000000654.1
ENSFALG00000000632.1	ENSFALT00000000659.1	ENSFALP00000000655.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.80e-19	66.8	61	119

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++++v +ly+ye+++d++L l+kG++++v+   e++++W+k+++ ++g++Gl+P+nFv+ ++
   Q: 61   QDKLVVALYNYEPKHDGDLGLRKGEKLRVL---EENGEWWKAQSLTTGQEGLIPHNFVALVN 119
           6899**************************...99***********************9886 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MGCCCSSDYD EDWIENIDIC ERCNYPIEPD SKRQRLIRNG SEVQDPLVSY EPSSPPRSPM 60
QDKLVVALYN YEPKHDGDLG LRKGEKLRVL EENGEWWKAQ SLTTGQEGLI PHNFVALVNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTGCT GCTGCAGCTC GGACTATGAC GAGGACTGGA TCGAGAACAT CGACATCTGC 60
GAGCGCTGCA ACTACCCCAT CGAGCCCGAC AGCAAGCGCC AGGTGAGGAG GGTCACAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0001772--C:immunological synapse
GO:0045121--C:membrane raft
GO:0000242--C:pericentriolar material
GO:0005524--F:ATP binding
GO:0004722--F:protein serine/threonine phosphatase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006882--P:cellular zinc ion homeostasis
GO:2001244--P:positive regulation of intrinsic apoptotic signaling pathway
GO:0050870--P:positive regulation of T cell activation
GO:0042493--P:response to drug
GO:0030217--P:T cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001315	Ailuropoda melanoleuca	66.91	0.00e+00	711.00
IUUC-Bta-013264	Bos taurus	71.13	0.00e+00	736.00
IUUC-Cfa-021161	Canis familiaris	66.73	0.00e+00	710.00
IUUC-Cpo-022492	Cavia porcellus	70.75	0.00e+00	728.00
IUUC-Dno-029365	Dasypus novemcinctus	67.88	0.00e+00	683.00
IUUC-Eca-033325	Equus caballus	71.48	0.00e+00	734.00
IUUC-Eeu-035004	Erinaceus europaeus	60.48	7.00e-149	520.00
IUUC-Fca-035908	Felis catus	70.55	0.00e+00	727.00
IUUC-Gga-040997	Gallus gallus	78.35	0.00e+00	811.00
IUUC-Ggo-045238	Gorilla gorilla	67.27	0.00e+00	718.00
IUUC-Hsa-047039	Homo sapiens	71.13	0.00e+00	734.00
IUUC-Itr-048479	Ictidomys tridecemlineatus	70.94	0.00e+00	733.00
IUUC-Laf-054499	Loxodonta africana	66.55	0.00e+00	707.00
IUUC-Meu-056879	Macropus eugenii	69.83	0.00e+00	719.00
IUUC-Mga-059971	Meleagris gallopavo	76.44	0.00e+00	785.00
IUUC-Mmr-060740	Microcebus murinus	70.40	0.00e+00	728.00
IUUC-Mdo-062192	Monodelphis domestica	71.70	0.00e+00	739.00
IUUC-Mmu-064241	Mus musculus	70.36	0.00e+00	724.00
IUUC-Mpu-066595	Mustela putorius furo	70.94	0.00e+00	729.00
IUUC-Mlu-067069	Myotis lucifugus	69.85	0.00e+00	717.00
IUUC-Opr-070472	Ochotona princeps	67.34	0.00e+00	711.00
IUUC-Ocu-074221	Oryctolagus cuniculus	70.42	0.00e+00	727.00
IUUC-Oga-088225	Otolemur garnettii	69.60	0.00e+00	717.00
IUUC-Ptr-090751	Pan troglodytes	88.29	2.00e-162	564.00
IUUC-Pan-091804	Papio anubis	71.32	0.00e+00	739.00
IUUC-Psi-093252	Pelodiscus sinensis	73.06	0.00e+00	734.00
IUUC-Pab-098168	Pongo abelii	70.89	0.00e+00	694.00
IUUC-Ppe-101646	Prunus persica	34.70	2.00e-23	104.00
IUUC-Rno-105542	Rattus norvegicus	69.98	0.00e+00	722.00
IUUC-Sha-107524	Sarcophilus harrisii	70.17	0.00e+00	726.00
IUUC-Sly-111528	Solanum lycopersicum	33.33	6.00e-23	102.00
IUUC-Stu-112331	Solanum tuberosum	34.74	6.00e-24	105.00
IUUC-Sar-113235	Sorex araneus	63.84	1.00e-167	582.00
IUUC-Ssc-115624	Sus scrofa	70.94	0.00e+00	731.00
IUUC-Ttr-129002	Tursiops truncatus	64.74	0.00e+00	674.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence