iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033233

Ensembl Protein ID

ENSECAP00000009410.1

UniProt Accession

F7BME5; F7BME5_HORSE

Protein Name

Uncharacterized protein

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000011550.1	ENSECAT00000011976.1	ENSECAP00000009410.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-18	66.9	132	187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 132  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 187
           689*************************..6999******9.5**************98 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAGNFDSEER SWYWGRLSRQ EAVALLQQRH GVFLVRDSST SPGDYVLSVS ENSRVSHYII 60
NSSGPRPPLP PSPAQPPPGM STSRLRIGDQ EFDSLPALLE FYKIHYLDTT TLIEPVSRSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGCA ACTTCGACTC GGAGGAGCGG GAGTAGCTGG TACTGGGGAC GGCTGAGCCG 60
GCAGGAGGCG GTGGCGCTGT TGCAGGGCCC AGCGGCACGG GGTGTTCCTG GTGCGGGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	97.99	4.00e-157	546.00
IUUC-Apl-003225	Anas platyrhynchos	91.56	2.00e-122	431.00
IUUC-Aca-004818	Anolis carolinensis	78.35	3.00e-93	334.00
IUUC-Ame-011721	Astyanax mexicanus	68.35	2.00e-116	411.00
IUUC-Bta-012320	Bos taurus	98.36	2.00e-160	557.00
IUUC-Cel-018307	Caenorhabditis elegans	30.51	6.00e-27	114.00
IUUC-Cja-019935	Callithrix jacchus	95.07	5.00e-163	566.00
IUUC-Cfa-021221	Canis familiaris	98.03	3.00e-160	557.00
IUUC-Cpo-021592	Cavia porcellus	85.00	6.00e-136	476.00
IUUC-Csa-024128	Chlorocebus sabaeus	97.54	3.00e-97	347.00
IUUC-Cho-024775	Choloepus hoffmanni	96.38	7.00e-159	552.00
IUUC-Dre-027390	Danio rerio	68.63	4.00e-116	410.00
IUUC-Dno-029847	Dasypus novemcinctus	98.36	2.00e-160	557.00
IUUC-Dor-030360	Dipodomys ordii	88.49	8.00e-152	529.00
IUUC-Ete-032604	Echinops telfairi	95.96	3.00e-125	440.00
IUUC-Eeu-034642	Erinaceus europaeus	96.86	1.00e-126	444.00
IUUC-Fca-035955	Felis catus	98.67	2.00e-130	457.00
IUUC-Fal-037152	Ficedula albicollis	86.74	4.00e-139	486.00
IUUC-Gmo-038849	Gadus morhua	67.41	5.00e-114	403.00
IUUC-Gga-040861	Gallus gallus	83.28	2.00e-146	511.00
IUUC-Gac-041627	Gasterosteus aculeatus	65.73	2.00e-116	411.00
IUUC-Ggo-045475	Gorilla gorilla	98.36	2.00e-160	557.00
IUUC-Hsa-046008	Homo sapiens	98.36	2.00e-160	557.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	97.70	7.00e-131	459.00
IUUC-Lch-050509	Latimeria chalumnae	80.65	2.00e-144	504.00
IUUC-Loc-052229	Lepisosteus oculatus	72.79	1.00e-104	372.00
IUUC-Laf-053896	Loxodonta africana	93.81	4.00e-162	563.00
IUUC-Mcc-055280	Macaca mulatta	98.36	2.00e-160	557.00
IUUC-Meu-056783	Macropus eugenii	96.41	2.00e-126	444.00
IUUC-Mga-059345	Meleagris gallopavo	91.93	2.00e-123	434.00
IUUC-Mdo-062691	Monodelphis domestica	87.34	8.00e-150	522.00
IUUC-Mmu-063691	Mus musculus	98.03	4.00e-160	556.00
IUUC-Mpu-065737	Mustela putorius furo	98.03	2.00e-160	557.00
IUUC-Mlu-067005	Myotis lucifugus	95.07	1.00e-155	541.00
IUUC-Nle-070154	Nomascus leucogenys	98.67	3.00e-130	456.00
IUUC-Opr-071114	Ochotona princeps	97.37	4.00e-162	563.00
IUUC-Ont-071696	Oreochromis niloticus	69.43	1.00e-112	399.00
IUUC-Oan-072967	Ornithorhynchus anatinus	91.92	7.00e-128	449.00
IUUC-Ocu-074025	Oryctolagus cuniculus	96.55	7.00e-96	342.00
IUUC-Olo-080293	Oryza longistaminata	40.00	1.70e+00	25.80
IUUC-Ola-087265	Oryzias latipes	67.38	1.00e-92	332.00
IUUC-Oga-088266	Otolemur garnettii	97.04	2.00e-159	554.00
IUUC-Oar-089221	Ovis aries	96.72	8.00e-156	542.00
IUUC-Ptr-091463	Pan troglodytes	93.73	4.00e-149	520.00
IUUC-Pan-092242	Papio anubis	98.03	2.00e-160	557.00
IUUC-Psi-093287	Pelodiscus sinensis	94.20	2.00e-126	444.00
IUUC-Pfo-097378	Poecilia formosa	65.83	1.00e-106	379.00
IUUC-Pab-097823	Pongo abelii	97.54	3.00e-97	347.00
IUUC-Pca-101068	Procavia capensis	98.36	2.00e-160	557.00
IUUC-Ptt-103815	Puccinia triticina	37.93	4.00e-09	55.10
IUUC-Rno-105288	Rattus norvegicus	98.03	5.00e-160	556.00
IUUC-Sar-113453	Sorex araneus	83.22	4.00e-142	497.00
IUUC-Tgu-116926	Taeniopygia guttata	85.90	6.00e-146	509.00
IUUC-Tru-118656	Takifugu rubripes	66.26	2.00e-116	411.00
IUUC-Tni-120497	Tetraodon nigroviridis	67.83	8.00e-112	396.00
IUUC-Tbe-127436	Tupaia belangeri	93.42	3.00e-141	494.00
IUUC-Ttr-129109	Tursiops truncatus	99.10	2.00e-129	454.00
IUUC-Vpa-130527	Vicugna pacos	98.03	2.00e-158	551.00
IUUC-Xtr-131808	Xenopus tropicalis	84.59	1.00e-147	515.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence