iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	circBase	miRTarBase	microRNA
TRANSFAC	RepTar	RAID2
Protein-protein Interaction
IID	HINT
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	78.19	0.00e+00	2180.00	IUUC-Hsa-046895
UBD/Alpha-Helix/UBA	78.19	0.00e+00	2180.00	IUUC-Hsa-046895

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Protein Sequence
(Fasta)

MFHEEVPNST HPQEQDCLPS QHANAYKDMP VGQENGGVSE AGECLSSTSC EYGPSTSAEA 60
CVLAATRRGP TLLHIDRHQI PAVEPSAQAL ELQGLGVDVY DQAVLEQGVL QQVDSAMHEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATGCGCTA AGGTTTGTCT CAACGCTCCG TCGCGGCGGT AGCGACGAAG AATTCGTTTG 60
GGCAGCCGCG TGGTTCTGGG TGAGTGTTCG GCAGCCGGAC AGAAGGCCGG GTGAGAGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER

Pfam

PF00271--Helicase_C
PF00176--SNF2_N

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0008023--C:transcription elongation factor complex
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0008094--F:DNA-dependent ATPase activity
GO:0008022--F:protein C-terminus binding
GO:0032403--F:protein complex binding
GO:0047485--F:protein N-terminus binding
GO:0030296--F:protein tyrosine kinase activator activity
GO:0070063--F:RNA polymerase binding
GO:0007256--P:activation of JNKK activity
GO:0007257--P:activation of JUN kinase activity
GO:0006284--P:base-excision repair
GO:0006974--P:cellular response to DNA damage stimulus
GO:0006281--P:DNA repair
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0035264--P:multicellular organism growth
GO:0045494--P:photoreceptor cell maintenance
GO:0032786--P:positive regulation of DNA-templated transcription, elongation
GO:0006290--P:pyrimidine dimer repair
GO:0032784--P:regulation of DNA-templated transcription, elongation
GO:0010332--P:response to gamma radiation
GO:0006979--P:response to oxidative stress
GO:0000303--P:response to superoxide
GO:0009636--P:response to toxic substance
GO:0009411--P:response to UV
GO:0010224--P:response to UV-B
GO:0010165--P:response to X-ray
GO:0006362--P:transcription elongation from RNA polymerase I promoter
GO:0006283--P:transcription-coupled nucleotide-excision repair

KEGG

mmu:319955

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000518	Aegilops tauschii	53.41	0.00e+00	635.00
IUUC-Aml-002021	Ailuropoda melanoleuca	76.64	0.00e+00	2121.00
IUUC-Atr-002868	Amborella trichopoda	52.46	0.00e+00	630.00
IUUC-Apl-003989	Anas platyrhynchos	73.79	0.00e+00	1464.00
IUUC-Aca-004609	Anolis carolinensis	70.02	0.00e+00	1298.00
IUUC-Aly-005912	Arabidopsis lyrata	51.88	0.00e+00	632.00
IUUC-Ath-006812	Arabidopsis thaliana	51.54	0.00e+00	630.00
IUUC-Ago-007719	Ashbya gossypii	52.45	6.00e-178	618.00
IUUC-Acl-008050	Aspergillus clavatus	53.31	5.00e-176	612.00
IUUC-Afl-008677	Aspergillus flavus	51.51	1.00e-166	580.00
IUUC-Afu-008975	Aspergillus fumigatus	53.72	4.00e-176	612.00
IUUC-Ani-009464	Aspergillus nidulans	54.09	2.00e-175	610.00
IUUC-Ang-009516	Aspergillus niger	53.89	5.00e-164	572.00
IUUC-Aor-010057	Aspergillus oryzae	49.85	9.00e-170	590.00
IUUC-Ate-010307	Aspergillus terreus	54.37	4.00e-165	575.00
IUUC-Ame-011055	Astyanax mexicanus	70.23	0.00e+00	1262.00
IUUC-Bgr-012211	Blumeria graminis	51.59	3.00e-164	573.00
IUUC-Bta-012761	Bos taurus	71.63	0.00e+00	1923.00
IUUC-Bci-013603	Botrytis cinerea	54.24	1.00e-179	624.00
IUUC-Bdi-014031	Brachypodium distachyon	51.80	0.00e+00	632.00
IUUC-Bol-015096	Brassica oleracea	52.93	0.00e+00	637.00
IUUC-Bra-017583	Brassica rapa	52.91	0.00e+00	631.00
IUUC-Cel-018275	Caenorhabditis elegans	36.13	2.00e-105	377.00
IUUC-Cja-019733	Callithrix jacchus	80.78	0.00e+00	1643.00
IUUC-Cfa-020631	Canis familiaris	76.19	0.00e+00	2097.00
IUUC-Cpo-022218	Cavia porcellus	75.11	0.00e+00	1455.00
IUUC-Cre-022710	Chlamydomonas reinhardtii	49.55	4.00e-152	533.00
IUUC-Csa-023723	Chlorocebus sabaeus	78.14	0.00e+00	2127.00
IUUC-Cho-024312	Choloepus hoffmanni	72.44	0.00e+00	916.00
IUUC-Cin-025376	Ciona intestinalis	52.40	0.00e+00	835.00
IUUC-Cgl-026654	Colletotrichum gloeosporioides	50.97	1.00e-163	570.00
IUUC-Cme-027109	Cyanidioschyzon merolae	51.82	6.00e-156	545.00
IUUC-Dre-028672	Danio rerio	84.36	0.00e+00	1010.00
IUUC-Dno-028893	Dasypus novemcinctus	74.63	0.00e+00	1979.00
IUUC-Dor-031114	Dipodomys ordii	69.39	0.00e+00	1802.00
IUUC-Dse-031225	Dothistroma septosporum	53.62	0.00e+00	629.00
IUUC-Ete-032713	Echinops telfairi	68.66	0.00e+00	903.00
IUUC-Eca-034071	Equus caballus	75.57	0.00e+00	2063.00
IUUC-Eeu-034781	Erinaceus europaeus	75.91	0.00e+00	1609.00
IUUC-Fca-036561	Felis catus	76.75	0.00e+00	2088.00
IUUC-Fal-037343	Ficedula albicollis	60.78	0.00e+00	1636.00
IUUC-Fox-037667	Fusarium oxysporum	45.60	2.00e-156	546.00
IUUC-Fso-038331	Fusarium solani	52.51	4.00e-160	559.00
IUUC-Gmo-039132	Gadus morhua	65.88	0.00e+00	1181.00
IUUC-Gga-040376	Gallus gallus	74.06	0.00e+00	1444.00
IUUC-Gac-042326	Gasterosteus aculeatus	78.21	0.00e+00	962.00
IUUC-Gma-043401	Glycine max	52.31	2.00e-179	623.00
IUUC-Ggo-044844	Gorilla gorilla	79.06	0.00e+00	2172.00
IUUC-Hsa-046895	Homo sapiens	78.73	0.00e+00	2161.00
IUUC-Itr-048071	Ictidomys tridecemlineatus	78.60	0.00e+00	2203.00
IUUC-Kpa-049261	Komagataella pastoris	50.60	0.00e+00	655.00
IUUC-Lch-049934	Latimeria chalumnae	57.85	0.00e+00	1310.00
IUUC-Lpe-051249	Leersia perrieri	48.81	6.00e-147	515.00
IUUC-Loc-052591	Lepisosteus oculatus	61.09	0.00e+00	1507.00
IUUC-Lma-053210	Leptosphaeria maculans	51.81	7.00e-167	581.00
IUUC-Laf-054403	Loxodonta africana	76.07	0.00e+00	2040.00
IUUC-Mcc-054876	Macaca mulatta	78.30	0.00e+00	2161.00
IUUC-Meu-056545	Macropus eugenii	60.30	4.00e-124	439.00
IUUC-Mor-057145	Magnaporthe oryzae	50.97	8.00e-171	594.00
IUUC-Mpo-057493	Magnaporthe poae	51.59	2.00e-167	583.00
IUUC-Mtr-057734	Medicago truncatula	51.66	5.00e-178	619.00
IUUC-Mga-059402	Meleagris gallopavo	73.99	0.00e+00	1448.00
IUUC-Mmr-061791	Microcebus murinus	78.49	0.00e+00	2187.00
IUUC-Mdo-062148	Monodelphis domestica	67.31	0.00e+00	1810.00
IUUC-Mac-064440	Musa acuminata	51.69	1.00e-172	600.00
IUUC-Mpu-066112	Mustela putorius furo	77.18	0.00e+00	2115.00
IUUC-Mlu-067057	Myotis lucifugus	76.58	0.00e+00	2090.00
IUUC-Nfi-068617	Neosartorya fischeri	53.89	8.00e-176	611.00
IUUC-Ncr-068920	Neurospora crassa	51.68	2.00e-171	597.00
IUUC-Nle-069992	Nomascus leucogenys	78.58	0.00e+00	2146.00
IUUC-Opr-070929	Ochotona princeps	72.03	0.00e+00	1679.00
IUUC-Ont-071740	Oreochromis niloticus	83.30	0.00e+00	1016.00
IUUC-Oan-073380	Ornithorhynchus anatinus	65.55	0.00e+00	812.00
IUUC-Ocu-074143	Oryctolagus cuniculus	72.31	0.00e+00	1892.00
IUUC-Oba-075626	Oryza barthii	52.27	6.00e-178	618.00
IUUC-Obr-076240	Oryza brachyantha	50.25	0.00e+00	633.00
IUUC-Ogl-077187	Oryza glaberrima	52.27	4.00e-178	619.00
IUUC-Ogu-078629	Oryza glumaepatula	49.21	6.00e-143	501.00
IUUC-Oin-079268	Oryza indica	52.45	2.00e-178	620.00
IUUC-Olo-080567	Oryza longistaminata	48.81	5.00e-143	502.00
IUUC-Oni-082122	Oryza nivara	52.45	3.00e-178	619.00
IUUC-Opu-083477	Oryza punctata	52.45	0.00e+00	632.00
IUUC-Oru-084783	Oryza rufipogon	52.45	2.00e-178	620.00
IUUC-Osa-086206	Oryza sativa	52.45	6.00e-177	614.00
IUUC-Oga-088414	Otolemur garnettii	75.33	0.00e+00	2093.00
IUUC-Oar-089697	Ovis aries	75.03	0.00e+00	2078.00
IUUC-Ptr-090856	Pan troglodytes	78.92	0.00e+00	2179.00
IUUC-Pan-092521	Papio anubis	78.48	0.00e+00	2156.00
IUUC-Psi-093037	Pelodiscus sinensis	65.17	0.00e+00	1542.00
IUUC-Pma-094456	Petromyzon marinus	65.54	0.00e+00	830.00
IUUC-Pno-094861	Phaeosphaeria nodorum	50.88	7.00e-167	581.00
IUUC-Ppa-095711	Physcomitrella patens	50.17	0.00e+00	633.00
IUUC-Pfo-096223	Poecilia formosa	56.27	0.00e+00	1460.00
IUUC-Pab-098595	Pongo abelii	78.73	0.00e+00	2150.00
IUUC-Pop-099531	Populus trichocarpa	51.64	1.00e-180	627.00
IUUC-Pca-100770	Procavia capensis	72.64	0.00e+00	714.00
IUUC-Ppe-101528	Prunus persica	51.39	0.00e+00	630.00
IUUC-Pva-102247	Pteropus vampyrus	71.94	0.00e+00	1104.00
IUUC-Pte-104217	Pyrenophora teres	53.10	3.00e-170	592.00
IUUC-Pyt-104797	Pyrenophora triticirepentis	52.29	5.00e-172	598.00
IUUC-Rno-105742	Rattus norvegicus	88.74	0.00e+00	2496.00
IUUC-Sce-106234	Saccharomyces cerevisiae	50.41	1.00e-176	613.00
IUUC-Sha-106622	Sarcophilus harrisii	64.53	0.00e+00	1694.00
IUUC-Sja-107874	Schizosaccharomyces japonicus	53.71	0.00e+00	641.00
IUUC-Spo-108021	Schizosaccharomyces pombe	50.53	0.00e+00	649.00
IUUC-Ssl-108500	Sclerotinia sclerotiorum	54.42	5.00e-178	618.00
IUUC-Smo-109132	Selaginella moellendorffii	51.44	3.00e-173	602.00
IUUC-Sit-110066	Setaria italica	52.69	0.00e+00	632.00
IUUC-Sly-111833	Solanum lycopersicum	53.40	0.00e+00	637.00
IUUC-Stu-112189	Solanum tuberosum	49.31	0.00e+00	637.00
IUUC-Sar-113511	Sorex araneus	66.77	0.00e+00	1481.00
IUUC-Sbi-114606	Sorghum bicolor	53.05	0.00e+00	632.00
IUUC-Ssc-116374	Sus scrofa	77.06	0.00e+00	2168.00
IUUC-Tgu-117153	Taeniopygia guttata	59.14	0.00e+00	1514.00
IUUC-Tru-118178	Takifugu rubripes	62.52	0.00e+00	1239.00
IUUC-Tsy-119524	Tarsius syrichta	76.56	0.00e+00	2148.00
IUUC-Tni-120546	Tetraodon nigroviridis	56.41	0.00e+00	1366.00
IUUC-Tca-121065	Theobroma cacao	50.95	3.00e-180	626.00
IUUC-Tre-121868	Trichoderma reesei	50.98	2.00e-159	557.00
IUUC-Tvi-122455	Trichoderma virens	51.25	3.00e-156	546.00
IUUC-Tae-123249	Triticum aestivum	53.41	0.00e+00	635.00
IUUC-Tur-126107	Triticum urartu	53.41	0.00e+00	636.00
IUUC-Tbe-127967	Tupaia belangeri	76.35	0.00e+00	1014.00
IUUC-Ttr-128768	Tursiops truncatus	76.17	0.00e+00	2155.00
IUUC-Vda-129884	Verticillium dahliae	51.51	2.00e-173	603.00
IUUC-Vpa-130521	Vicugna pacos	79.34	0.00e+00	1036.00
IUUC-Vvi-130838	Vitis vinifera	51.75	7.00e-178	618.00
IUUC-Xtr-132056	Xenopus tropicalis	55.93	0.00e+00	1073.00
IUUC-Xma-133113	Xiphophorus maculatus	83.42	0.00e+00	1021.00
IUUC-Yli-134344	Yarrowia lipolytica	55.52	0.00e+00	635.00
IUUC-Zma-134837	Zea mays	51.56	6.00e-179	621.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence