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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046796
UUCD1 version UUC-HoS-00834
Ensembl Protein ID ENSP00000274457.3
UniProt Accession Q96JP0; B2RE47; Q8N3V8; Q9H704; Q9NPL6; Q9NPL9; FEM1C_HUMAN
Genbank Protein ID AAL37627.1; AAO64429.1; BAB47414.1; BAB15096.1; BAG38144.1; EAW48963.1; AAH28369.1; CAB96953.1; CAB96957.1; CAD38531.1
Protein Name Protein fem-1 homolog C; FEM1-gamma
Genbank Nucleotide ID AF391093; AY249188; AB058688; AK025265; AK315803; CH471086; BC028369; AL365409; AL365415; AL831817
Gene Name FEM1C; KIAA1785
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000145780.7 ENST00000274457.4 ENSP00000274457.3
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarmiRNAMapSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
InWeb_IM
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
UniProtBioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/Other 43.72 9.00e-87 317.00 IUUC-Cel-018331
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit.
 Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit.
Protein Sequence
(Fasta)
MDLKTAVFNA ARDGKLRLLT KLLASKSKEE VSSLISEKTN GATPLLMAAR YGHLDMVEFL 60
LEQCSASIEV GGSVNFDGET IEGAPPLWAA SAAGHLKVVQ SLLNHGASVN NTTLTNSTPL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046796|E3,Cullin RING/Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGCCCCGCG CCTAGGCTGT TGCTGGCCGC GGCCGCCGCC CTCCCCCGGC CCAATGGCGT 60
GGCGGCACAG TCAGTGATGT GACGCTCAGG CTTGTCCGGC CCCCGGCTCG CAGCCCATTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046796|E3,Cullin RING/Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0833--Ubl conjugation pathway
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
Pfam

PF12796--Ank_2
PRINTS

PR01415--ANKYRIN
SMART

SM00248--ANK
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0016567--P:protein ubiquitination
KEGG hsa:56929
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002342 Ailuropoda melanoleuca 99.84 0.00e+00 1248.00
IUUC-Apl-003985 Anas platyrhynchos 90.93 0.00e+00 948.00
IUUC-Aca-005021 Anolis carolinensis 93.52 0.00e+00 1172.00
IUUC-Ame-011230 Astyanax mexicanus 84.76 0.00e+00 1051.00
IUUC-Bta-013387 Bos taurus 99.84 0.00e+00 1248.00
IUUC-Cel-018331 Caenorhabditis elegans 39.09 2.00e-92 333.00
IUUC-Cja-019699 Callithrix jacchus 100.00 0.00e+00 1249.00
IUUC-Cfa-020538 Canis familiaris 99.28 0.00e+00 1108.00
IUUC-Csa-023288 Chlorocebus sabaeus 100.00 0.00e+00 1249.00
IUUC-Cho-024656 Choloepus hoffmanni 97.22 0.00e+00 914.00
IUUC-Cin-025401 Ciona intestinalis 46.83 1.00e-149 523.00
IUUC-Csv-025937 Ciona savignyi 48.90 2.00e-160 559.00
IUUC-Dno-029410 Dasypus novemcinctus 99.68 0.00e+00 1247.00
IUUC-Dor-030434 Dipodomys ordii 96.60 0.00e+00 1217.00
IUUC-Dme-031725 Drosophila melanogaster 49.55 3.00e-168 585.00
IUUC-Ete-033142 Echinops telfairi 99.46 0.00e+00 1123.00
IUUC-Eca-033604 Equus caballus 99.35 0.00e+00 1240.00
IUUC-Eeu-035045 Erinaceus europaeus 99.51 0.00e+00 1244.00
IUUC-Fca-035992 Felis catus 99.51 0.00e+00 1244.00
IUUC-Fal-037002 Ficedula albicollis 93.19 0.00e+00 1145.00
IUUC-Fox-037717 Fusarium oxysporum 37.17 3.00e-05 45.10
IUUC-Gmo-038702 Gadus morhua 69.74 0.00e+00 887.00
IUUC-Gga-040317 Gallus gallus 90.60 0.00e+00 1074.00
IUUC-Gac-041410 Gasterosteus aculeatus 82.04 0.00e+00 1031.00
IUUC-Ggo-045522 Gorilla gorilla 100.00 0.00e+00 1249.00
IUUC-Itr-048316 Ictidomys tridecemlineatus 99.84 0.00e+00 1248.00
IUUC-Lch-050179 Latimeria chalumnae 74.35 0.00e+00 951.00
IUUC-Loc-051857 Lepisosteus oculatus 75.65 0.00e+00 971.00
IUUC-Laf-053354 Loxodonta africana 99.35 0.00e+00 1243.00
IUUC-Mcc-055364 Macaca mulatta 100.00 0.00e+00 1249.00
IUUC-Meu-055961 Macropus eugenii 95.30 0.00e+00 1158.00
IUUC-Mla-058995 Melampsora laricipopulina 32.29 9.00e-10 55.50
IUUC-Mga-059954 Meleagris gallopavo 53.26 2.00e-157 549.00
IUUC-Mdo-062747 Monodelphis domestica 95.46 0.00e+00 1160.00
IUUC-Mmu-064254 Mus musculus 99.51 0.00e+00 1214.00
IUUC-Mpu-065985 Mustela putorius furo 99.68 0.00e+00 1246.00
IUUC-Mlu-067989 Myotis lucifugus 99.19 0.00e+00 1205.00
IUUC-Nle-069932 Nomascus leucogenys 100.00 0.00e+00 1249.00
IUUC-Opr-070186 Ochotona princeps 99.25 0.00e+00 1069.00
IUUC-Ont-072533 Oreochromis niloticus 84.30 0.00e+00 1044.00
IUUC-Ocu-074213 Oryctolagus cuniculus 99.68 0.00e+00 1246.00
IUUC-Ola-086744 Oryzias latipes 82.20 0.00e+00 1036.00
IUUC-Olu-087673 Ostreococcus lucimarinus 31.22 7.00e-22 98.60
IUUC-Oga-088031 Otolemur garnettii 99.68 0.00e+00 1246.00
IUUC-Oar-089759 Ovis aries 99.84 0.00e+00 1248.00
IUUC-Ptr-091472 Pan troglodytes 100.00 0.00e+00 1249.00
IUUC-Pan-092660 Papio anubis 100.00 0.00e+00 1112.00
IUUC-Psi-093528 Pelodiscus sinensis 94.33 0.00e+00 1144.00
IUUC-Pma-094411 Petromyzon marinus 75.64 0.00e+00 956.00
IUUC-Pno-094944 Phaeosphaeria nodorum 33.87 5.00e-17 83.20
IUUC-Pfo-096936 Poecilia formosa 83.09 0.00e+00 1027.00
IUUC-Pab-098073 Pongo abelii 100.00 0.00e+00 1249.00
IUUC-Pva-102915 Pteropus vampyrus 65.11 0.00e+00 815.00
IUUC-Rno-104915 Rattus norvegicus 99.68 0.00e+00 1214.00
IUUC-Sha-106623 Sarcophilus harrisii 95.46 0.00e+00 1156.00
IUUC-Sar-113422 Sorex araneus 99.33 0.00e+00 1211.00
IUUC-Ssc-116086 Sus scrofa 60.92 0.00e+00 673.00
IUUC-Tgu-117192 Taeniopygia guttata 93.35 0.00e+00 1148.00
IUUC-Tru-118533 Takifugu rubripes 80.85 0.00e+00 1034.00
IUUC-Tsy-119026 Tarsius syrichta 98.68 7.00e-171 593.00
IUUC-Tni-119869 Tetraodon nigroviridis 82.04 0.00e+00 1036.00
IUUC-Ttr-128277 Tursiops truncatus 97.90 0.00e+00 1029.00
IUUC-Vpa-130370 Vicugna pacos 99.84 0.00e+00 1248.00
IUUC-Xtr-132661 Xenopus tropicalis 89.63 0.00e+00 1134.00
Created Date 25-Jun-2017

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