iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-057671

Ensembl Protein ID

KEH24077

UniProt Accession

A0A072U2X8; A0A072U2X8_MEDTR

Genbank Protein ID

KEH24077.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

CM001223

Gene Name

MTR_7g103210

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_7g103210	KEH24077	KEH24077

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.60e-101	339.3	802	1148

Active Site

Position(s)	Description	Evidence
1116	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksf 96
           s+lk++++v+fv      E+gld+gG+++efl+ +ske ++p++glf +++++++ l pn ++ + + + l++ eflGr++gkal++g lld+ +s++f
   Q: 802  SKLKSSIHVSFVSecgltEAGLDYGGLSKEFLTDISKEAFSPEYGLFSQTSTSDSLLIPNASARFLD-NGLQMIEFLGRVVGKALYEGILLDYSFSHVF 899
           6899*********9999999********************************999999999998865.9****************************** PP
   S: 97   yklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafre 195
            ++llg+   l++l+++dpely+sl+++k++ + d++el+ld+t+  +ee++g+++++eLk+gG++i+VtneNk +Y++++++y+l+++i    +af++
   Q: 900  VQKLLGRYSFLDELSTLDPELYRSLMYVKNY-DGDVKELSLDFTV--TEESFGKRHVVELKSGGKDISVTNENKMQYIHAMADYKLNQQILLFSNAFYR 995
           ********999******************99.6788887666665..5888************************************************ PP
   S: 196  GfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.. 291
           G++++i++++l+lF+++e+++l++G   +id++d+k++t+y+ggy+e s++i+ Fwev+++f+ +er+++L+FvT++sr Pl Gf++l+p  f+i+k  
   Q: 996  GLTDLISPSWLKLFNASEFNQLLSGGnYDIDIDDFKSNTRYTGGYNEGSRTIKIFWEVIKGFEPKERCMLLKFVTSCSRGPLLGFKYLQPP-FTIHKva 1093
           ************************9989*************************************************************98.999999* PP
   S: 292  .........dasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
                     ++d +rlPs++TC+n+LkLP+Y+   +l+ kLlyAi++++gFels
   Q: 1094 cdvplwatiGGQDaERLPSASTCYNTLKLPTYKRPGTLRAKLLYAISSNAGFELS 1148
           ********955555**************************************985 PP

Organism

Medicago truncatula

Protein Sequence
(Fasta)

MDAPRKHQVS LRGASAKEIT RDDLLQKVSR ERELRNYAKR AASAALFIQR VWRRFKVTKM 60
VALQLQQEWE TSVNCYTGVM TSNWISNNLL RPFLFFVTRF SNHYQKVHSK KIDSMKICFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAACTTTTC CTTCCTTGTT CTTTCTTTCT TCTAAATAAA TCAAACTTAT TAGTAGTTGC 60
GATAAAGAGA GTAGAACAAA ATTTTGGGTG AGGAAAAAAG TAAATCGCGA GAAGATTAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

mtr:MTR_7g103210

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	56.73	0.00e+00	1085.00
IUUC-Aml-002107	Ailuropoda melanoleuca	39.79	3.00e-111	395.00
IUUC-Atr-003017	Amborella trichopoda	56.39	0.00e+00	1316.00
IUUC-Apl-003328	Anas platyrhynchos	39.96	1.00e-112	400.00
IUUC-Aly-005794	Arabidopsis lyrata	58.50	0.00e+00	1315.00
IUUC-Ath-007269	Arabidopsis thaliana	58.35	0.00e+00	1352.00
IUUC-Acl-008158	Aspergillus clavatus	38.24	8.00e-76	278.00
IUUC-Afl-008398	Aspergillus flavus	38.78	1.00e-75	278.00
IUUC-Afu-008937	Aspergillus fumigatus	38.70	2.00e-76	280.00
IUUC-Ani-009252	Aspergillus nidulans	38.87	1.00e-82	301.00
IUUC-Ang-009773	Aspergillus niger	38.16	1.00e-75	278.00
IUUC-Aor-009940	Aspergillus oryzae	38.78	1.00e-75	278.00
IUUC-Ate-010395	Aspergillus terreus	38.28	5.00e-75	276.00
IUUC-Bta-013547	Bos taurus	39.79	4.00e-112	399.00
IUUC-Bdi-014502	Brachypodium distachyon	56.41	0.00e+00	1197.00
IUUC-Bol-015093	Brassica oleracea	58.88	0.00e+00	1322.00
IUUC-Bra-016722	Brassica rapa	58.95	0.00e+00	1346.00
IUUC-Cel-018447	Caenorhabditis elegans	37.99	6.00e-96	345.00
IUUC-Cja-019855	Callithrix jacchus	39.25	3.00e-111	396.00
IUUC-Cfa-020066	Canis familiaris	38.91	5.00e-106	378.00
IUUC-Cpo-021504	Cavia porcellus	40.14	6.00e-113	401.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	46.67	4.00e-109	389.00
IUUC-Csa-023579	Chlorocebus sabaeus	39.61	3.00e-112	399.00
IUUC-Cin-025750	Ciona intestinalis	37.78	2.00e-104	373.00
IUUC-Csv-026016	Ciona savignyi	38.05	1.00e-107	384.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	39.01	8.00e-86	311.00
IUUC-Cne-026841	Cryptococcus neoformans	35.53	5.00e-87	315.00
IUUC-Dre-028271	Danio rerio	40.67	4.00e-114	405.00
IUUC-Dno-029054	Dasypus novemcinctus	39.79	2.00e-111	396.00
IUUC-Dor-030938	Dipodomys ordii	37.99	1.00e-104	374.00
IUUC-Dse-031416	Dothistroma septosporum	33.56	1.00e-77	284.00
IUUC-Dme-031602	Drosophila melanogaster	38.45	2.00e-108	386.00
IUUC-Eca-034411	Equus caballus	39.96	3.00e-112	399.00
IUUC-Eeu-035201	Erinaceus europaeus	34.53	8.00e-75	275.00
IUUC-Fca-036594	Felis catus	39.25	4.00e-110	392.00
IUUC-Fal-037317	Ficedula albicollis	39.96	2.00e-112	400.00
IUUC-Fox-037788	Fusarium oxysporum	33.04	7.00e-83	301.00
IUUC-Fso-038088	Fusarium solani	37.83	9.00e-83	301.00
IUUC-Gmo-039412	Gadus morhua	39.79	2.00e-111	396.00
IUUC-Gga-040149	Gallus gallus	39.96	1.00e-112	400.00
IUUC-Gac-042088	Gasterosteus aculeatus	39.79	3.00e-110	392.00
IUUC-Gma-042728	Glycine max	83.56	0.00e+00	1991.00
IUUC-Ggo-045279	Gorilla gorilla	39.43	1.00e-111	397.00
IUUC-Hsa-045660	Homo sapiens	39.43	9.00e-112	397.00
IUUC-Hvu-047102	Hordeum vulgare	57.14	0.00e+00	1082.00
IUUC-Lch-050664	Latimeria chalumnae	39.61	5.00e-110	392.00
IUUC-Lpe-050755	Leersia perrieri	52.41	0.00e+00	1052.00
IUUC-Loc-052791	Lepisosteus oculatus	40.43	7.00e-111	394.00
IUUC-Laf-053902	Loxodonta africana	39.89	6.00e-113	401.00
IUUC-Mcc-054730	Macaca mulatta	39.61	3.00e-112	399.00
IUUC-Meu-056527	Macropus eugenii	34.70	6.00e-90	325.00
IUUC-Mor-057021	Magnaporthe oryzae	36.94	1.00e-73	271.00
IUUC-Mpo-057570	Magnaporthe poae	36.83	9.00e-78	285.00
IUUC-Mga-059260	Meleagris gallopavo	39.96	2.00e-112	400.00
IUUC-Mvi-060445	Microbotryum violaceum	37.71	8.00e-100	358.00
IUUC-Mmr-060804	Microcebus murinus	39.79	5.00e-112	398.00
IUUC-Mdo-062575	Monodelphis domestica	39.43	3.00e-110	392.00
IUUC-Mmu-063636	Mus musculus	39.40	1.00e-111	397.00
IUUC-Mac-064989	Musa acuminata	57.06	0.00e+00	1192.00
IUUC-Mlu-067952	Myotis lucifugus	39.79	1.00e-111	397.00
IUUC-Nfi-068280	Neosartorya fischeri	38.70	2.00e-76	280.00
IUUC-Ncr-068869	Neurospora crassa	35.49	1.00e-83	304.00
IUUC-Nle-069153	Nomascus leucogenys	39.43	1.00e-111	397.00
IUUC-Opr-070554	Ochotona princeps	39.79	8.00e-112	397.00
IUUC-Ont-071372	Oreochromis niloticus	40.50	2.00e-112	400.00
IUUC-Ocu-074183	Oryctolagus cuniculus	40.32	2.00e-114	406.00
IUUC-Oba-075213	Oryza barthii	57.55	0.00e+00	1032.00
IUUC-Obr-076320	Oryza brachyantha	55.94	0.00e+00	1125.00
IUUC-Ogl-077093	Oryza glaberrima	56.78	0.00e+00	1182.00
IUUC-Ogu-078235	Oryza glumaepatula	54.47	0.00e+00	1083.00
IUUC-Oin-080058	Oryza indica	55.99	0.00e+00	1153.00
IUUC-Olo-080742	Oryza longistaminata	56.71	0.00e+00	1199.00
IUUC-Ome-081741	Oryza meridionalis	55.34	0.00e+00	1142.00
IUUC-Oni-082616	Oryza nivara	54.82	0.00e+00	1099.00
IUUC-Opu-083529	Oryza punctata	57.82	0.00e+00	1070.00
IUUC-Oru-085128	Oryza rufipogon	56.59	0.00e+00	983.00
IUUC-Osa-085557	Oryza sativa	64.25	0.00e+00	904.00
IUUC-Ola-087337	Oryzias latipes	40.50	3.00e-112	399.00
IUUC-Olu-087902	Ostreococcus lucimarinus	43.72	4.00e-96	344.00
IUUC-Oga-088342	Otolemur garnettii	39.72	7.00e-111	394.00
IUUC-Oar-090234	Ovis aries	38.91	2.00e-106	380.00
IUUC-Ptr-091661	Pan troglodytes	39.25	3.00e-111	395.00
IUUC-Pan-092728	Papio anubis	39.36	2.00e-110	393.00
IUUC-Psi-093251	Pelodiscus sinensis	39.27	5.00e-98	352.00
IUUC-Pma-094195	Petromyzon marinus	39.26	5.00e-109	388.00
IUUC-Ppa-095544	Physcomitrella patens	64.86	0.00e+00	729.00
IUUC-Pfo-097472	Poecilia formosa	40.50	1.00e-112	400.00
IUUC-Pab-098570	Pongo abelii	39.43	2.00e-111	397.00
IUUC-Pop-099058	Populus trichocarpa	60.70	0.00e+00	986.00
IUUC-Pca-100110	Procavia capensis	36.59	9.00e-100	357.00
IUUC-Ppe-101281	Prunus persica	65.36	0.00e+00	1541.00
IUUC-Pva-102887	Pteropus vampyrus	38.19	4.00e-104	372.00
IUUC-Pgr-103513	Puccinia graminis	38.58	1.00e-92	333.00
IUUC-Rno-106028	Rattus norvegicus	38.39	7.00e-95	341.00
IUUC-Sce-106446	Saccharomyces cerevisiae	34.02	6.00e-73	268.00
IUUC-Sha-107331	Sarcophilus harrisii	39.25	2.00e-110	393.00
IUUC-Smo-109537	Selaginella moellendorffii	43.65	0.00e+00	830.00
IUUC-Sit-109811	Setaria italica	55.15	0.00e+00	1144.00
IUUC-Sly-111013	Solanum lycopersicum	60.88	0.00e+00	1389.00
IUUC-Sbi-114433	Sorghum bicolor	56.42	0.00e+00	1180.00
IUUC-Sre-115038	Sporisorium reilianum	44.71	5.00e-94	338.00
IUUC-Ssc-116103	Sus scrofa	39.79	3.00e-111	396.00
IUUC-Tgu-117275	Taeniopygia guttata	39.96	2.00e-112	399.00
IUUC-Tru-118681	Takifugu rubripes	40.32	2.00e-112	400.00
IUUC-Tca-121770	Theobroma cacao	65.81	0.00e+00	1495.00
IUUC-Tre-121892	Trichoderma reesei	41.70	3.00e-87	316.00
IUUC-Tae-124300	Triticum aestivum	81.88	6.00e-136	475.00
IUUC-Tur-126086	Triticum urartu	54.60	0.00e+00	1064.00
IUUC-Tbe-127461	Tupaia belangeri	36.25	2.00e-88	320.00
IUUC-Ttr-129269	Tursiops truncatus	39.79	2.00e-111	396.00
IUUC-Vda-129748	Verticillium dahliae	37.15	3.00e-73	269.00
IUUC-Vvi-131524	Vitis vinifera	67.41	0.00e+00	1572.00
IUUC-Xtr-132146	Xenopus tropicalis	40.14	2.00e-112	399.00
IUUC-Xma-133526	Xiphophorus maculatus	40.50	1.00e-112	400.00
IUUC-Yli-134496	Yarrowia lipolytica	37.17	1.00e-79	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence