iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000012446.1	ENSLACT00000014237.1	ENSLACP00000014138.1
ENSLACG00000012446.1	ENSLACT00000014238.1	ENSLACP00000014139.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.60e-06	27.6	335	374

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++  Cl  w     ++s   +CP Cr
   Q: 335  CKICTENDKD-VKIEPCGHLMCSLCLTSW-----LESDGHTCPFCR 374
           99**999999.******************.....7899999****8 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

FCSAVDKKLA EKASRLLEKL VCLCQQPKMQ LKNSPPYLLE LVPETYQHFH LVLGNYELRS 60
EALWENEYFR VYVENLYSKV KQTTRLFKTA AIYWKENVRE NMRNLTKLSL IFSHMLAEVK 120

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Nucleotide Sequence
(Fasta)

TTCTGCTCAG CGGTGGACAA GAAGCTGGCG GAGAAGGCTT CCAGGCTGCT GGAGAAGTTG 60
GTGTGTCTCT GCCAGCAGCC CAAAATGCAG CTCAAGAACA GCCCGCCATA TCTGCTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence