iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108117

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Set1 complex component swd3; COMPASS component swd3; Complex proteins associated with set1 protein swd3

Genbank Nucleotide ID

CU329671

Gene Name

swd3; SPBC354.03

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC354.03	SPBC354.03.1	SPBC354.03.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-41	136.9	136	174
UBD/Beta-Prp	1.30e-64	216.3	47	272

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v++++f   +tllvsGs+D t+++W+l +g++l+
   Q: 136  GHTNYVSSIDFnpLGTLLVSGSWDETVRIWNLQDGTCLR 174
           8**********85449*********************97 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           ++tl+gh+ksv + v +sp+k+++at+s dgtik+w++ t  l  +l gh  ++++vk+   +k+l+++s+D+ti++wd+++++ v+ lkgh+
   Q: 47   YCTLFGHEKSVTC-VSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGSKYLASASDDKTIRIWDFEKRCSVRCLKGHT 138
           89*******7766.******************************************************************************* PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls 187
           ++v s++f+p g  lvsGs+d+t+r+w+l+ g+cl+ +l  h++ + +v+++ dg l++++s+D++ r+Wd+ +g++l+tl +  + +   l+
   Q: 139  NYVSSIDFNPLGTLLVSGSWDETVRIWNLQDGTCLR-MLPAHSEPIISVSISADGTLCATASYDGMARIWDVLSGQCLKTLVEPINVPLSNLQ 230
           ************************************.********************************************888999****** PP
   S: 188  fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvr 229
           f++n+k+l+   l+++++lwd++++++vr++  h ++ +s+ 
   Q: 231  FTENRKYLLVSNLNSQIRLWDYRRNRVVRIFDSHVNTRYSMS 272
           ************************************999986 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

The Set1 complex specifically methylates 'Lys-4' of histone H3.

Protein Sequence
(Fasta)

MDSTAQQFPL NHDLQVQKDQ KGVVEEDEEQ IHKRIRNYES HSGFSEYCTL FGHEKSVTCV 60
SVSPNKRWIA TSSSDGTIKI WSALTFRLEC TLFGHYRGIS QVKWATGSKY LASASDDKTI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCTTGTGCA TACAATAAAG CTGGATGCTT AAAAAATTGA CTGGCATCAT TGTAATTTTA 60
TAATCTACAT ATGCAAAAAG CCCATGAACT TTTTTTCTTG TACATAGACT CTAGAAAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0048188--C:Set1C/COMPASS complex
GO:0070869--P:heterochromatin assembly involved in chromatin silencing
GO:0051568--P:histone H3-K4 methylation

KEGG

spo:SPBC354.03

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000502	Aegilops tauschii	33.77	9.00e-42	161.00
IUUC-Aml-002420	Ailuropoda melanoleuca	47.98	2.00e-64	237.00
IUUC-Atr-002439	Amborella trichopoda	41.96	1.00e-58	218.00
IUUC-Apl-003436	Anas platyrhynchos	50.00	4.00e-62	229.00
IUUC-Aca-004259	Anolis carolinensis	47.98	2.00e-64	237.00
IUUC-Aly-005723	Arabidopsis lyrata	40.17	2.00e-53	200.00
IUUC-Ath-007308	Arabidopsis thaliana	40.17	7.00e-54	201.00
IUUC-Acl-008045	Aspergillus clavatus	33.74	2.00e-53	201.00
IUUC-Afl-008596	Aspergillus flavus	39.29	9.00e-56	209.00
IUUC-Afu-009074	Aspergillus fumigatus	34.36	7.00e-54	202.00
IUUC-Ani-009318	Aspergillus nidulans	36.31	4.00e-55	207.00
IUUC-Ang-009775	Aspergillus niger	35.20	2.00e-55	207.00
IUUC-Aor-010222	Aspergillus oryzae	39.29	8.00e-56	209.00
IUUC-Ate-010583	Aspergillus terreus	34.69	3.00e-54	203.00
IUUC-Ame-011349	Astyanax mexicanus	47.53	2.00e-63	234.00
IUUC-Bgr-011968	Blumeria graminis	37.42	5.00e-56	209.00
IUUC-Bta-013016	Bos taurus	47.98	3.00e-64	236.00
IUUC-Bci-013948	Botrytis cinerea	45.70	5.00e-55	206.00
IUUC-Bdi-014263	Brachypodium distachyon	36.36	8.00e-58	215.00
IUUC-Bol-015900	Brassica oleracea	40.87	2.00e-53	200.00
IUUC-Bra-017143	Brassica rapa	40.43	5.00e-54	202.00
IUUC-Cel-018355	Caenorhabditis elegans	44.64	1.00e-60	224.00
IUUC-Cja-019936	Callithrix jacchus	47.98	2.00e-64	237.00
IUUC-Cfa-020596	Canis familiaris	47.98	2.00e-64	237.00
IUUC-Cpo-021318	Cavia porcellus	47.98	2.00e-64	237.00
IUUC-Cre-022935	Chlamydomonas reinhardtii	40.55	2.00e-54	203.00
IUUC-Csa-023053	Chlorocebus sabaeus	47.98	2.00e-64	237.00
IUUC-Cho-024642	Choloepus hoffmanni	41.09	2.00e-58	217.00
IUUC-Cin-025495	Ciona intestinalis	47.09	1.00e-62	231.00
IUUC-Csv-025988	Ciona savignyi	46.19	3.00e-62	229.00
IUUC-Cne-027025	Cryptococcus neoformans	30.19	8.00e-31	125.00
IUUC-Cme-027119	Cyanidioschyzon merolae	37.79	1.00e-52	197.00
IUUC-Dre-027521	Danio rerio	47.53	9.00e-64	234.00
IUUC-Dno-029739	Dasypus novemcinctus	47.98	4.00e-64	236.00
IUUC-Dor-030966	Dipodomys ordii	47.98	3.00e-64	236.00
IUUC-Dse-031189	Dothistroma septosporum	40.56	5.00e-63	233.00
IUUC-Dme-031613	Drosophila melanogaster	47.09	3.00e-64	236.00
IUUC-Ete-033098	Echinops telfairi	46.64	4.00e-59	219.00
IUUC-Eca-033790	Equus caballus	47.98	2.00e-64	237.00
IUUC-Eeu-034805	Erinaceus europaeus	44.39	2.00e-54	204.00
IUUC-Fca-035901	Felis catus	47.98	2.00e-64	237.00
IUUC-Fal-037413	Ficedula albicollis	47.98	2.00e-64	237.00
IUUC-Fox-037876	Fusarium oxysporum	34.20	6.00e-36	142.00
IUUC-Gmo-039131	Gadus morhua	47.98	1.00e-64	237.00
IUUC-Ggr-040071	Gaeumannomyces graminis	35.55	2.00e-48	185.00
IUUC-Gga-040789	Gallus gallus	47.98	2.00e-64	237.00
IUUC-Gac-042634	Gasterosteus aculeatus	47.53	7.00e-64	235.00
IUUC-Gma-043692	Glycine max	40.34	1.00e-57	214.00
IUUC-Ggo-044443	Gorilla gorilla	47.98	2.00e-64	237.00
IUUC-Hsa-046290	Homo sapiens	47.98	2.00e-64	237.00
IUUC-Hvu-047077	Hordeum vulgare	41.83	2.00e-50	190.00
IUUC-Itr-048954	Ictidomys tridecemlineatus	47.98	2.00e-64	237.00
IUUC-Kpa-049404	Komagataella pastoris	44.76	1.00e-50	191.00
IUUC-Lch-049539	Latimeria chalumnae	47.98	2.00e-64	236.00
IUUC-Lpe-051082	Leersia perrieri	35.54	1.00e-58	217.00
IUUC-Loc-051743	Lepisosteus oculatus	47.53	2.00e-63	234.00
IUUC-Lma-053188	Leptosphaeria maculans	39.44	2.00e-59	221.00
IUUC-Laf-053472	Loxodonta africana	47.53	2.00e-57	214.00
IUUC-Mcc-055603	Macaca mulatta	47.98	2.00e-64	237.00
IUUC-Meu-056440	Macropus eugenii	47.53	6.00e-55	205.00
IUUC-Mor-056965	Magnaporthe oryzae	37.05	8.00e-49	186.00
IUUC-Mpo-057333	Magnaporthe poae	35.02	2.00e-45	175.00
IUUC-Mtr-057951	Medicago truncatula	41.63	1.00e-57	214.00
IUUC-Mla-058896	Melampsora laricipopulina	35.99	1.00e-50	191.00
IUUC-Mga-060046	Meleagris gallopavo	48.43	8.00e-65	238.00
IUUC-Mvi-060453	Microbotryum violaceum	42.98	2.00e-55	207.00
IUUC-Mmr-061436	Microcebus murinus	46.49	1.00e-55	208.00
IUUC-Mdo-062204	Monodelphis domestica	47.09	1.00e-63	234.00
IUUC-Mmu-063917	Mus musculus	47.98	2.00e-64	237.00
IUUC-Mac-065310	Musa acuminata	33.75	6.00e-57	212.00
IUUC-Mpu-066072	Mustela putorius furo	47.98	2.00e-64	237.00
IUUC-Mlu-068209	Myotis lucifugus	47.98	2.00e-64	237.00
IUUC-Nfi-068538	Neosartorya fischeri	33.74	5.00e-53	200.00
IUUC-Ncr-068651	Neurospora crassa	33.06	5.00e-50	190.00
IUUC-Nle-069383	Nomascus leucogenys	46.05	2.00e-57	214.00
IUUC-Opr-070937	Ochotona princeps	45.74	3.00e-56	209.00
IUUC-Ont-071458	Oreochromis niloticus	47.53	9.00e-64	234.00
IUUC-Oan-073597	Ornithorhynchus anatinus	47.98	3.00e-64	236.00
IUUC-Oba-075292	Oryza barthii	35.05	4.00e-47	179.00
IUUC-Obr-076723	Oryza brachyantha	33.55	3.00e-43	166.00
IUUC-Ogl-077251	Oryza glaberrima	35.60	3.00e-56	209.00
IUUC-Ogu-078882	Oryza glumaepatula	41.10	3.00e-49	187.00
IUUC-Oin-079601	Oryza indica	32.16	3.00e-51	193.00
IUUC-Olo-080976	Oryza longistaminata	37.50	1.00e-48	184.00
IUUC-Ome-081430	Oryza meridionalis	35.83	2.00e-56	210.00
IUUC-Oni-082182	Oryza nivara	40.54	6.00e-49	186.00
IUUC-Opu-083880	Oryza punctata	36.36	3.00e-56	210.00
IUUC-Oru-084935	Oryza rufipogon	33.55	1.00e-46	177.00
IUUC-Osa-085706	Oryza sativa	35.60	3.00e-56	209.00
IUUC-Ola-087134	Oryzias latipes	47.53	8.00e-64	235.00
IUUC-Olu-087660	Ostreococcus lucimarinus	33.75	1.00e-28	117.00
IUUC-Oga-088672	Otolemur garnettii	47.98	2.00e-64	236.00
IUUC-Oar-089860	Ovis aries	45.74	3.00e-55	206.00
IUUC-Ptr-091513	Pan troglodytes	47.98	2.00e-64	237.00
IUUC-Pan-092046	Papio anubis	47.98	2.00e-64	237.00
IUUC-Psi-093192	Pelodiscus sinensis	47.98	2.00e-64	237.00
IUUC-Pno-094881	Phaeosphaeria nodorum	37.50	1.00e-56	211.00
IUUC-Ppa-095865	Physcomitrella patens	43.28	1.00e-62	231.00
IUUC-Pfo-097434	Poecilia formosa	47.53	9.00e-64	234.00
IUUC-Pab-098758	Pongo abelii	46.05	2.00e-57	214.00
IUUC-Pop-099778	Populus trichocarpa	38.17	3.00e-55	206.00
IUUC-Pca-100281	Procavia capensis	50.97	1.00e-43	167.00
IUUC-Ppe-101291	Prunus persica	43.36	2.00e-55	206.00
IUUC-Pva-103020	Pteropus vampyrus	47.98	2.00e-64	237.00
IUUC-Pgr-103589	Puccinia graminis	31.01	6.00e-45	172.00
IUUC-Ptt-103745	Puccinia triticina	32.32	2.00e-30	124.00
IUUC-Pte-104153	Pyrenophora teres	38.05	7.00e-60	222.00
IUUC-Pyt-104712	Pyrenophora triticirepentis	43.95	1.00e-58	217.00
IUUC-Rno-105858	Rattus norvegicus	47.98	2.00e-64	237.00
IUUC-Sha-107101	Sarcophilus harrisii	47.98	2.00e-64	237.00
IUUC-Sja-107858	Schizosaccharomyces japonicus	54.01	3.00e-98	349.00
IUUC-Smo-109155	Selaginella moellendorffii	39.58	7.00e-63	231.00
IUUC-Sit-110688	Setaria italica	35.69	9.00e-57	211.00
IUUC-Sly-110891	Solanum lycopersicum	33.83	2.00e-59	220.00
IUUC-Stu-112365	Solanum tuberosum	34.23	3.00e-59	219.00
IUUC-Sbi-114284	Sorghum bicolor	35.35	7.00e-56	208.00
IUUC-Sre-115180	Sporisorium reilianum	41.96	4.00e-46	176.00
IUUC-Ssc-116204	Sus scrofa	47.98	3.00e-64	236.00
IUUC-Tgu-117172	Taeniopygia guttata	47.98	2.00e-64	237.00
IUUC-Tru-118320	Takifugu rubripes	47.98	1.00e-64	237.00
IUUC-Tni-120660	Tetraodon nigroviridis	51.91	2.00e-54	203.00
IUUC-Tca-121051	Theobroma cacao	33.13	3.00e-55	206.00
IUUC-Tre-122237	Trichoderma reesei	35.65	1.00e-54	205.00
IUUC-Tvi-122635	Trichoderma virens	36.39	8.00e-54	202.00
IUUC-Tae-123971	Triticum aestivum	36.70	3.00e-58	216.00
IUUC-Tur-126219	Triticum urartu	40.98	9.00e-39	151.00
IUUC-Tme-127061	Tuber melanosporum	45.74	8.00e-61	225.00
IUUC-Tbe-127488	Tupaia belangeri	46.64	4.00e-57	213.00
IUUC-Ttr-129309	Tursiops truncatus	48.83	3.00e-62	229.00
IUUC-Uma-129585	Ustilago maydis	40.00	1.00e-48	184.00
IUUC-Vda-129907	Verticillium dahliae	36.64	6.00e-54	203.00
IUUC-Vpa-130384	Vicugna pacos	46.19	2.00e-55	207.00
IUUC-Vvi-131269	Vitis vinifera	33.33	7.00e-54	202.00
IUUC-Xtr-131945	Xenopus tropicalis	47.98	3.00e-64	236.00
IUUC-Xma-132997	Xiphophorus maculatus	47.53	9.00e-64	234.00
IUUC-Yli-134418	Yarrowia lipolytica	37.50	1.00e-59	221.00
IUUC-Zma-135765	Zea mays	38.96	1.00e-55	208.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence