iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005248

UUCD1 version

UUC-AnC-00711

Ensembl Protein ID

ENSACAP00000011171.2

UniProt Accession

G1KL50; G1KL50_ANOCA

Protein Name

Uncharacterized protein

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000011224.3	ENSACAT00000011405.3	ENSACAP00000011171.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.60e-106	354.6	745	1082

Active Site

Position(s)	Description	Evidence
1050	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +  + ++++flGr+lgkal++
   Q: 745  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-SYARHYYFLGRMLGKALYE 830
           689**********99**9**************************************9**99999965.9****************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++++f+++llg+  ++++++l+++dpe+yk+l ++k++ e d+eelgl++t+   ++ lge++++eLkpgG++ipVt +N
   Q: 831  NMLVELPFASFFLSKLLGTsaDVDIHHLASLDPEMYKNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKPGGKDIPVTSAN 914
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i++++ afr+G+ +v++le+l++F+++e+++li+G    i ++dl+++t+y ggy++d+p+i+ Fw+v+e+
   Q: 915  RIAYIHLVADYRLNKQIRQHCLAFRQGLANVVNLEWLRMFDQQEIQVLISGAqVPICLDDLRNFTNYSGGYSADHPVIKIFWRVVES 1001
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f+++e++++L+FvT++sr Pl Gf+el p  f++++ +sd +rlP+++TC+n+LkLPe+  ++ +++kLlyAie ++gFels
   Q: 1002 FTDDEKRKLLKFVTSCSRPPLLGFKELYPA-FCVHNGGSDlERLPTASTCMNLLKLPEFYDENLMRSKLLYAIECAAGFELS 1082
           ****************************88.*****99999**************************************985 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MFSFEGEFKT RPKVSLGGAS KKEEKASLLH RTQEERRKRE EERRRLKNAI IIQSFVRGYR 60
DRKHQYAIQR SEFDRYANLT QSGGSFSTAN GSNLTLLVRQ LLFFYRHNED SKRLIWICQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCCTGTCA TCTGGAGTAT CAGCTCTCCC TCCTCATTTG GTGTCACCTG CAAACTTGCC 60
TCTGTATTCT ACCTGCTCAG ACTGCCTTGG TTTTACCTCA GAGGGCAGGG AGAGGTATGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

KEGG

acs:100555273

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	35.74	2.00e-94	341.00
IUUC-Aml-001355	Ailuropoda melanoleuca	87.05	0.00e+00	1810.00
IUUC-Atr-002669	Amborella trichopoda	35.24	2.00e-102	367.00
IUUC-Apl-003731	Anas platyrhynchos	94.01	0.00e+00	1985.00
IUUC-Aly-005768	Arabidopsis lyrata	34.88	4.00e-112	399.00
IUUC-Ath-006576	Arabidopsis thaliana	34.00	6.00e-114	405.00
IUUC-Ago-007748	Ashbya gossypii	41.19	2.00e-78	287.00
IUUC-Acl-008158	Aspergillus clavatus	38.17	8.00e-77	282.00
IUUC-Afl-008398	Aspergillus flavus	37.87	6.00e-79	289.00
IUUC-Afu-008937	Aspergillus fumigatus	38.22	4.00e-79	290.00
IUUC-Ani-009252	Aspergillus nidulans	37.95	8.00e-81	295.00
IUUC-Ang-009773	Aspergillus niger	34.08	5.00e-80	293.00
IUUC-Aor-009940	Aspergillus oryzae	37.87	6.00e-79	289.00
IUUC-Ate-010395	Aspergillus terreus	33.91	2.00e-80	294.00
IUUC-Ame-010769	Astyanax mexicanus	63.31	0.00e+00	1047.00
IUUC-Bgr-012269	Blumeria graminis	38.65	1.00e-77	283.00
IUUC-Bta-012841	Bos taurus	86.27	0.00e+00	1819.00
IUUC-Bci-013743	Botrytis cinerea	29.35	1.00e-87	318.00
IUUC-Bdi-014123	Brachypodium distachyon	47.79	5.00e-106	379.00
IUUC-Bol-015390	Brassica oleracea	46.36	2.00e-103	370.00
IUUC-Bra-016853	Brassica rapa	34.47	4.00e-110	392.00
IUUC-Cel-018638	Caenorhabditis elegans	40.34	4.00e-92	333.00
IUUC-Cja-019743	Callithrix jacchus	86.90	0.00e+00	1820.00
IUUC-Cfa-021031	Canis familiaris	88.60	0.00e+00	1863.00
IUUC-Cpo-022401	Cavia porcellus	87.10	0.00e+00	1836.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.50	3.00e-85	308.00
IUUC-Csa-024107	Chlorocebus sabaeus	88.83	0.00e+00	1883.00
IUUC-Cho-024750	Choloepus hoffmanni	80.21	0.00e+00	784.00
IUUC-Cin-025432	Ciona intestinalis	44.90	2.00e-98	352.00
IUUC-Csv-026016	Ciona savignyi	33.33	2.00e-94	340.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.21	2.00e-88	320.00
IUUC-Cne-026841	Cryptococcus neoformans	35.74	7.00e-94	338.00
IUUC-Cme-027265	Cyanidioschyzon merolae	47.34	2.00e-105	377.00
IUUC-Dre-028196	Danio rerio	79.15	0.00e+00	1628.00
IUUC-Dno-029024	Dasypus novemcinctus	89.58	0.00e+00	1895.00
IUUC-Dor-030483	Dipodomys ordii	88.25	0.00e+00	667.00
IUUC-Dse-031416	Dothistroma septosporum	33.56	9.00e-79	288.00
IUUC-Dme-031946	Drosophila melanogaster	37.46	0.00e+00	697.00
IUUC-Ete-032240	Echinops telfairi	79.95	6.00e-170	591.00
IUUC-Eca-033828	Equus caballus	88.79	0.00e+00	1850.00
IUUC-Eeu-034604	Erinaceus europaeus	83.46	1.00e-124	441.00
IUUC-Fca-035907	Felis catus	87.64	0.00e+00	1875.00
IUUC-Fal-037389	Ficedula albicollis	94.19	0.00e+00	2016.00
IUUC-Fox-037788	Fusarium oxysporum	37.25	6.00e-92	332.00
IUUC-Fso-038088	Fusarium solani	35.47	5.00e-88	319.00
IUUC-Gmo-039254	Gadus morhua	67.13	0.00e+00	1241.00
IUUC-Ggr-039941	Gaeumannomyces graminis	33.45	9.00e-84	305.00
IUUC-Gga-040310	Gallus gallus	93.45	0.00e+00	1999.00
IUUC-Gac-042054	Gasterosteus aculeatus	70.98	0.00e+00	1297.00
IUUC-Gma-042836	Glycine max	34.00	1.00e-103	370.00
IUUC-Ggo-045031	Gorilla gorilla	89.10	0.00e+00	1890.00
IUUC-Hsa-045880	Homo sapiens	89.01	0.00e+00	1889.00
IUUC-Hvu-047770	Hordeum vulgare	48.28	7.00e-107	381.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	77.01	7.00e-175	606.00
IUUC-Kpa-049307	Komagataella pastoris	36.75	4.00e-66	246.00
IUUC-Lch-050403	Latimeria chalumnae	83.48	0.00e+00	1706.00
IUUC-Lpe-051428	Leersia perrieri	46.90	1.00e-97	350.00
IUUC-Loc-052218	Lepisosteus oculatus	82.69	0.00e+00	1715.00
IUUC-Lma-053096	Leptosphaeria maculans	38.79	1.00e-82	301.00
IUUC-Laf-054162	Loxodonta africana	85.63	0.00e+00	1606.00
IUUC-Mcc-055127	Macaca mulatta	88.83	0.00e+00	1882.00
IUUC-Meu-056187	Macropus eugenii	83.04	5.00e-107	382.00
IUUC-Mor-057021	Magnaporthe oryzae	33.51	4.00e-80	293.00
IUUC-Mpo-057570	Magnaporthe poae	36.24	3.00e-77	283.00
IUUC-Mtr-058154	Medicago truncatula	35.13	5.00e-106	379.00
IUUC-Mla-059124	Melampsora laricipopulina	47.78	2.00e-102	365.00
IUUC-Mga-059581	Meleagris gallopavo	93.14	0.00e+00	1982.00
IUUC-Mvi-060445	Microbotryum violaceum	38.66	2.00e-104	373.00
IUUC-Mmr-061360	Microcebus murinus	85.54	0.00e+00	1735.00
IUUC-Mdo-062194	Monodelphis domestica	89.36	0.00e+00	1959.00
IUUC-Mmu-064189	Mus musculus	86.43	0.00e+00	1858.00
IUUC-Mac-065275	Musa acuminata	49.88	2.00e-111	396.00
IUUC-Mpu-066439	Mustela putorius furo	86.89	0.00e+00	1811.00
IUUC-Mlu-068228	Myotis lucifugus	84.67	0.00e+00	1798.00
IUUC-Nfi-068280	Neosartorya fischeri	38.43	1.00e-79	291.00
IUUC-Ncr-068869	Neurospora crassa	34.68	3.00e-82	300.00
IUUC-Nle-069687	Nomascus leucogenys	88.60	0.00e+00	1832.00
IUUC-Opr-070592	Ochotona princeps	93.50	2.00e-110	393.00
IUUC-Ont-071836	Oreochromis niloticus	80.06	0.00e+00	1680.00
IUUC-Oan-072800	Ornithorhynchus anatinus	93.73	0.00e+00	2009.00
IUUC-Ocu-074587	Oryctolagus cuniculus	89.38	0.00e+00	1893.00
IUUC-Oba-075006	Oryza barthii	49.14	3.00e-109	390.00
IUUC-Obr-076133	Oryza brachyantha	48.66	2.00e-108	387.00
IUUC-Ogl-077003	Oryza glaberrima	49.14	3.00e-109	389.00
IUUC-Ogu-078947	Oryza glumaepatula	49.14	1.00e-109	390.00
IUUC-Oin-080058	Oryza indica	36.47	1.00e-95	344.00
IUUC-Olo-080475	Oryza longistaminata	49.14	2.00e-109	390.00
IUUC-Ome-081342	Oryza meridionalis	46.40	5.00e-97	349.00
IUUC-Oni-082385	Oryza nivara	49.14	2.00e-109	390.00
IUUC-Opu-083176	Oryza punctata	49.14	4.00e-109	389.00
IUUC-Oru-084554	Oryza rufipogon	46.40	6.00e-97	348.00
IUUC-Osa-085355	Oryza sativa	49.14	1.00e-109	390.00
IUUC-Ola-087209	Oryzias latipes	78.95	0.00e+00	1627.00
IUUC-Olu-087699	Ostreococcus lucimarinus	43.67	5.00e-90	324.00
IUUC-Oga-088776	Otolemur garnettii	84.03	0.00e+00	1704.00
IUUC-Oar-089441	Ovis aries	85.36	0.00e+00	1799.00
IUUC-Ptr-091273	Pan troglodytes	88.92	0.00e+00	1887.00
IUUC-Pan-091981	Papio anubis	88.83	0.00e+00	1884.00
IUUC-Psi-093203	Pelodiscus sinensis	92.95	0.00e+00	1738.00
IUUC-Pma-094738	Petromyzon marinus	64.87	0.00e+00	1337.00
IUUC-Pno-095132	Phaeosphaeria nodorum	35.18	1.00e-59	224.00
IUUC-Ppa-095682	Physcomitrella patens	37.18	4.00e-115	409.00
IUUC-Pfo-097511	Poecilia formosa	80.33	0.00e+00	1692.00
IUUC-Pab-098634	Pongo abelii	86.07	0.00e+00	1806.00
IUUC-Pop-099574	Populus trichocarpa	41.44	4.00e-94	339.00
IUUC-Pca-100987	Procavia capensis	96.34	0.00e+00	780.00
IUUC-Ppe-102040	Prunus persica	41.86	7.00e-98	352.00
IUUC-Pva-103034	Pteropus vampyrus	83.05	0.00e+00	1705.00
IUUC-Pgr-103513	Puccinia graminis	40.14	2.00e-107	384.00
IUUC-Ptt-103967	Puccinia triticina	42.54	1.00e-95	344.00
IUUC-Pte-104105	Pyrenophora teres	38.01	4.00e-81	296.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	37.80	6.00e-81	296.00
IUUC-Rno-105380	Rattus norvegicus	85.76	0.00e+00	1596.00
IUUC-Sce-106446	Saccharomyces cerevisiae	39.18	1.00e-67	251.00
IUUC-Sha-107108	Sarcophilus harrisii	85.73	0.00e+00	1800.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	44.39	8.00e-98	351.00
IUUC-Spo-108097	Schizosaccharomyces pombe	44.44	7.00e-97	348.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	28.27	6.00e-84	305.00
IUUC-Smo-109537	Selaginella moellendorffii	36.08	2.00e-102	367.00
IUUC-Sit-110457	Setaria italica	49.02	5.00e-102	365.00
IUUC-Sly-111362	Solanum lycopersicum	35.44	4.00e-103	369.00
IUUC-Sar-113687	Sorex araneus	79.52	0.00e+00	890.00
IUUC-Sbi-113882	Sorghum bicolor	48.28	2.00e-99	357.00
IUUC-Sre-115038	Sporisorium reilianum	44.47	2.00e-98	353.00
IUUC-Ssc-116168	Sus scrofa	78.41	0.00e+00	716.00
IUUC-Tgu-116729	Taeniopygia guttata	93.55	0.00e+00	1994.00
IUUC-Tru-118068	Takifugu rubripes	78.12	0.00e+00	1625.00
IUUC-Tsy-118942	Tarsius syrichta	88.38	0.00e+00	689.00
IUUC-Tni-120732	Tetraodon nigroviridis	77.18	0.00e+00	1585.00
IUUC-Tca-121737	Theobroma cacao	35.09	8.00e-109	388.00
IUUC-Tre-121892	Trichoderma reesei	36.06	1.00e-87	318.00
IUUC-Tvi-122354	Trichoderma virens	35.85	6.00e-89	322.00
IUUC-Tae-125466	Triticum aestivum	48.04	2.00e-106	380.00
IUUC-Tur-126086	Triticum urartu	36.08	3.00e-94	340.00
IUUC-Tme-127102	Tuber melanosporum	35.89	2.00e-93	337.00
IUUC-Tbe-127351	Tupaia belangeri	77.11	0.00e+00	1422.00
IUUC-Ttr-129061	Tursiops truncatus	84.96	0.00e+00	1774.00
IUUC-Uma-129343	Ustilago maydis	44.96	5.00e-100	359.00
IUUC-Vda-129748	Verticillium dahliae	38.38	1.00e-80	294.00
IUUC-Vvi-131234	Vitis vinifera	35.48	1.00e-105	377.00
IUUC-Xtr-132094	Xenopus tropicalis	87.57	0.00e+00	1845.00
IUUC-Xma-133923	Xiphophorus maculatus	80.52	0.00e+00	1695.00
IUUC-Yli-134496	Yarrowia lipolytica	40.04	6.00e-90	325.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence