iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020893

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03001424

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000006409.3	ENSCAFT00000010356.3	ENSCAFP00000009601.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-07	32.7	12	53
UBD/SH3	5.30e-30	103.5	386	440

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+e ++   +vlpC+H+f++ Clq++     ++ ke rCP Cr
   Q: 12   CPVCFEKLDVTAKVLPCQHTFCKPCLQRI----FKAHKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + +l++y+a   deL l+kG+ ++v+   +   gWl+gv+  +g+ G+fP+n+v 
   Q: 386  NMFVALHSYSAHGPDELDLHKGEGIRVL--GKYPDGWLRGVSLVTGRVGIFPNNYVI 440
           7889************************..77788********************96 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDDLTLLDLL ECPVCFEKLD VTAKVLPCQH TFCKPCLQRI FKAHKELRCP ECRTLVFCSI 60
EALPANLLLV RLLDGVRSGQ SSGRGGSFRR PGVLTSQDSR KSRTDPRGLQ SSPFRLVPNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGAAGACC GCGAGGATGG GGCGAGGACC CCCACCCCCC CGGCCCCGAG GTGCGCGCGA 60
CGTGTGCAAG TTTCAGGAGA ATTTCCTGAG CCGGATCCCC CTCCACACGA GGGCAGAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	93.69	0.00e+00	1202.00
IUUC-Apl-003443	Anas platyrhynchos	60.96	8.00e-176	610.00
IUUC-Aca-004632	Anolis carolinensis	56.02	3.00e-171	595.00
IUUC-Bta-013400	Bos taurus	91.18	0.00e+00	1112.00
IUUC-Cel-018180	Caenorhabditis elegans	28.36	2.00e-23	104.00
IUUC-Cja-019686	Callithrix jacchus	77.99	0.00e+00	971.00
IUUC-Cpo-021638	Cavia porcellus	83.77	0.00e+00	1068.00
IUUC-Csa-023846	Chlorocebus sabaeus	90.18	0.00e+00	1138.00
IUUC-Cho-024609	Choloepus hoffmanni	89.21	6.00e-173	600.00
IUUC-Dno-028940	Dasypus novemcinctus	87.62	0.00e+00	1107.00
IUUC-Dor-030491	Dipodomys ordii	79.77	3.00e-133	469.00
IUUC-Dse-031414	Dothistroma septosporum	34.33	4.00e-08	53.90
IUUC-Ete-032513	Echinops telfairi	87.37	0.00e+00	1090.00
IUUC-Eca-034241	Equus caballus	92.81	0.00e+00	1189.00
IUUC-Eeu-034636	Erinaceus europaeus	83.96	0.00e+00	971.00
IUUC-Fca-035862	Felis catus	92.40	0.00e+00	1162.00
IUUC-Gga-040748	Gallus gallus	54.64	3.00e-144	505.00
IUUC-Ggo-045267	Gorilla gorilla	90.32	0.00e+00	1155.00
IUUC-Hsa-045761	Homo sapiens	89.90	0.00e+00	1148.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	86.45	0.00e+00	1103.00
IUUC-Lch-050498	Latimeria chalumnae	44.83	4.00e-119	422.00
IUUC-Laf-054061	Loxodonta africana	80.84	0.00e+00	858.00
IUUC-Mcc-054746	Macaca mulatta	89.44	0.00e+00	1111.00
IUUC-Meu-056390	Macropus eugenii	61.01	1.00e-91	331.00
IUUC-Mmr-061390	Microcebus murinus	85.50	0.00e+00	922.00
IUUC-Mdo-062951	Monodelphis domestica	74.25	0.00e+00	980.00
IUUC-Mmu-063840	Mus musculus	80.06	0.00e+00	1027.00
IUUC-Mpu-065840	Mustela putorius furo	94.33	0.00e+00	1228.00
IUUC-Mlu-067378	Myotis lucifugus	87.24	0.00e+00	1074.00
IUUC-Nle-069535	Nomascus leucogenys	86.03	0.00e+00	1068.00
IUUC-Opr-070739	Ochotona princeps	83.13	0.00e+00	1055.00
IUUC-Oan-073468	Ornithorhynchus anatinus	67.26	0.00e+00	785.00
IUUC-Ocu-074343	Oryctolagus cuniculus	84.50	0.00e+00	1036.00
IUUC-Oga-088276	Otolemur garnettii	79.81	0.00e+00	1001.00
IUUC-Oar-090315	Ovis aries	89.15	0.00e+00	1102.00
IUUC-Ptr-091119	Pan troglodytes	89.63	0.00e+00	1148.00
IUUC-Pan-092158	Papio anubis	91.51	0.00e+00	845.00
IUUC-Psi-092959	Pelodiscus sinensis	60.11	0.00e+00	742.00
IUUC-Pab-097675	Pongo abelii	89.76	0.00e+00	1132.00
IUUC-Pca-101021	Procavia capensis	80.00	0.00e+00	982.00
IUUC-Pva-102619	Pteropus vampyrus	91.00	0.00e+00	1102.00
IUUC-Rno-105918	Rattus norvegicus	80.33	0.00e+00	1035.00
IUUC-Sha-107391	Sarcophilus harrisii	69.33	0.00e+00	887.00
IUUC-Sja-107661	Schizosaccharomyces japonicus	44.83	4.00e-10	59.30
IUUC-Sar-113148	Sorex araneus	83.68	0.00e+00	663.00
IUUC-Ssc-116219	Sus scrofa	83.05	3.00e-130	457.00
IUUC-Tgu-116584	Taeniopygia guttata	57.89	1.00e-111	396.00
IUUC-Tsy-118968	Tarsius syrichta	84.31	1.00e-167	583.00
IUUC-Tbe-128007	Tupaia belangeri	91.80	0.00e+00	837.00
IUUC-Ttr-128499	Tursiops truncatus	88.93	0.00e+00	1140.00
IUUC-Vpa-130075	Vicugna pacos	82.64	2.00e-79	289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence