iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	79.38	2.00e-121	432.00	IUUC-Hsa-045936
E3 activity/RING/RING	78.20	6.00e-120	427.00	IUUC-Mmu-063373

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSMPLRPFSA VPQDVASARV CRSKAKDKER EEPHEKTLGH SMSHSSNISK AVSPPSASAP 60
VSAFSRTSVT PSTQDICRIC HCEGDGESPL ITPCRCTGSL HFVHQACLQQ WIKSSDTRCC 120

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Nucleotide Sequence
(Fasta)

CTTGAAGTCC ATGGCCCAAA ATGACGCTGC CAGTGGAGAC TCTCTTCCTT GAAGAAGACC 60
ACCAGCTCGG AGGCTGGGAT GAGCATGCCA CTGCGCCCGT TCTCGGCCGT CCCCCAAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR033275--MARCH-like
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51292--ZF_RING_CH

Pfam

PF12906--RINGv

SMART

SM00744--RINGv

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002495--P:antigen processing and presentation of peptide antigen via MHC class II
GO:0045347--P:negative regulation of MHC class II biosynthetic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013415	Bos taurus	78.20	3.00e-123	434.00
IUUC-Cel-018329	Caenorhabditis elegans	43.21	1.00e-11	64.30
IUUC-Cfa-020901	Canis familiaris	77.85	3.00e-120	424.00
IUUC-Cpo-021679	Cavia porcellus	79.22	1.00e-117	415.00
IUUC-Csa-023704	Chlorocebus sabaeus	76.63	7.00e-117	413.00
IUUC-Dre-027670	Danio rerio	80.65	1.00e-113	402.00
IUUC-Dno-028902	Dasypus novemcinctus	78.20	5.00e-122	430.00
IUUC-Dme-031717	Drosophila melanogaster	55.42	2.00e-58	220.00
IUUC-Eca-033918	Equus caballus	78.63	1.00e-105	375.00
IUUC-Gmo-039585	Gadus morhua	80.89	6.00e-113	400.00
IUUC-Gga-040516	Gallus gallus	75.78	7.00e-123	432.00
IUUC-Gac-041554	Gasterosteus aculeatus	80.89	2.00e-113	401.00
IUUC-Hsa-045936	Homo sapiens	76.98	1.00e-116	412.00
IUUC-Lch-049853	Latimeria chalumnae	81.71	5.00e-116	410.00
IUUC-Loc-052142	Lepisosteus oculatus	78.00	4.00e-108	384.00
IUUC-Laf-054075	Loxodonta africana	91.76	5.00e-99	353.00
IUUC-Mcc-054834	Macaca mulatta	76.98	2.00e-117	415.00
IUUC-Mmr-061603	Microcebus murinus	80.34	7.00e-127	446.00
IUUC-Mdo-062578	Monodelphis domestica	75.52	9.00e-123	432.00
IUUC-Mmu-063373	Mus musculus	76.47	8.00e-119	419.00
IUUC-Nle-069774	Nomascus leucogenys	76.98	4.00e-117	414.00
IUUC-Ola-086344	Oryzias latipes	82.95	3.00e-104	370.00
IUUC-Oga-088670	Otolemur garnettii	79.52	2.00e-111	394.00
IUUC-Ptr-090574	Pan troglodytes	76.29	2.00e-116	411.00
IUUC-Pan-092925	Papio anubis	76.63	1.00e-117	415.00
IUUC-Psi-093085	Pelodiscus sinensis	87.76	1.00e-115	409.00
IUUC-Pma-094229	Petromyzon marinus	69.40	8.00e-70	256.00
IUUC-Pfo-097524	Poecilia formosa	77.27	4.00e-106	377.00
IUUC-Pab-098165	Pongo abelii	77.32	1.00e-117	415.00
IUUC-Rno-105837	Rattus norvegicus	76.47	8.00e-119	419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence