iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-018756

Ensembl Protein ID

ENSCJAP00000017986.2

UniProt Accession

F7I7B0; F7I7B0_CALJA

Genbank Protein ID

JAB12582.1; JAB32487.1; JAB46382.1

Protein Name

Protein kinase C and casein kinase substrate in neurons protein 2 isoform A

Genbank Nucleotide ID

ACFV01166550; GAMR01001445; GAMP01006373

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000009771.2	ENSCJAT00000019013.2	ENSCJAP00000017986.2
ENSCJAG00000009771.2	ENSCJAT00000056111.1	ENSCJAP00000042066.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.00e-16	59.4	430	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ + ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 430  RVRALYDYEGQEHDELSFKAGDELTKM-EDEDEQGWCKG-RLDNGQVGLYPANYVEAIQ 486
           799***********************9.9**********.59*************9885 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MSVAYDDSIG VEVSSDSFWE VGNYKRTVKR IDDGHRLCTD LMNCLHERAR IEKAYAQQLT 60
EWARRWRQLV EKGPQYGTVE KAWTAVMSEA ERVSELHLEV KASLMNEDFE KIKNWQKEAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTCCAACT GGGTAGGTGT CTCTGACTGA GAAGAGGCGG CGTCAGGAAC TACGTGGCTA 60
TGGCTGCTCT GGCAGTGATC CTGAAGACTG GCACAAAGGG GAATGGAGCC ACACAGAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0016301--F:kinase activity
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	94.86	0.00e+00	872.00
IUUC-Apl-003574	Anas platyrhynchos	88.09	0.00e+00	780.00
IUUC-Aca-004251	Anolis carolinensis	81.03	0.00e+00	741.00
IUUC-Ame-011756	Astyanax mexicanus	66.67	0.00e+00	667.00
IUUC-Bta-013193	Bos taurus	91.36	0.00e+00	813.00
IUUC-Cel-018168	Caenorhabditis elegans	31.72	4.00e-61	228.00
IUUC-Cfa-020545	Canis familiaris	95.68	0.00e+00	905.00
IUUC-Cpo-022000	Cavia porcellus	89.30	0.00e+00	894.00
IUUC-Csa-024030	Chlorocebus sabaeus	96.85	0.00e+00	780.00
IUUC-Dre-028104	Danio rerio	64.00	4.00e-163	567.00
IUUC-Dno-029429	Dasypus novemcinctus	93.61	0.00e+00	791.00
IUUC-Dor-030122	Dipodomys ordii	87.24	0.00e+00	787.00
IUUC-Dme-032120	Drosophila melanogaster	43.06	6.00e-105	374.00
IUUC-Eca-033367	Equus caballus	92.39	0.00e+00	844.00
IUUC-Eeu-034821	Erinaceus europaeus	76.75	0.00e+00	669.00
IUUC-Fca-036079	Felis catus	95.09	0.00e+00	867.00
IUUC-Fal-036682	Ficedula albicollis	88.72	0.00e+00	782.00
IUUC-Gmo-039681	Gadus morhua	65.10	2.00e-156	545.00
IUUC-Gga-040717	Gallus gallus	88.94	0.00e+00	785.00
IUUC-Gac-042262	Gasterosteus aculeatus	64.75	3.00e-171	594.00
IUUC-Ggo-044841	Gorilla gorilla	97.33	0.00e+00	840.00
IUUC-Hsa-046411	Homo sapiens	97.12	0.00e+00	838.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	95.47	0.00e+00	844.00
IUUC-Loc-051975	Lepisosteus oculatus	70.86	0.00e+00	686.00
IUUC-Laf-053839	Loxodonta africana	90.81	0.00e+00	825.00
IUUC-Mcc-055783	Macaca mulatta	96.91	0.00e+00	837.00
IUUC-Mga-060087	Meleagris gallopavo	83.19	0.00e+00	717.00
IUUC-Mmr-060827	Microcebus murinus	96.09	0.00e+00	884.00
IUUC-Mmu-064109	Mus musculus	94.65	0.00e+00	870.00
IUUC-Mpu-066591	Mustela putorius furo	95.27	0.00e+00	879.00
IUUC-Mlu-067826	Myotis lucifugus	93.62	0.00e+00	862.00
IUUC-Nle-069797	Nomascus leucogenys	97.33	0.00e+00	840.00
IUUC-Oan-073076	Ornithorhynchus anatinus	85.51	1.00e-155	542.00
IUUC-Ocu-074425	Oryctolagus cuniculus	94.24	0.00e+00	843.00
IUUC-Ola-087556	Oryzias latipes	65.23	9.00e-162	563.00
IUUC-Oga-089009	Otolemur garnettii	86.85	0.00e+00	794.00
IUUC-Oar-089806	Ovis aries	91.77	0.00e+00	816.00
IUUC-Ptr-091111	Pan troglodytes	96.91	0.00e+00	836.00
IUUC-Pan-091749	Papio anubis	94.20	0.00e+00	825.00
IUUC-Psi-093704	Pelodiscus sinensis	87.66	0.00e+00	794.00
IUUC-Pfo-096680	Poecilia formosa	63.55	1.00e-167	582.00
IUUC-Pab-098584	Pongo abelii	97.79	3.00e-166	577.00
IUUC-Pva-102649	Pteropus vampyrus	94.03	0.00e+00	845.00
IUUC-Rno-105431	Rattus norvegicus	93.65	0.00e+00	878.00
IUUC-Sha-106641	Sarcophilus harrisii	90.56	0.00e+00	814.00
IUUC-Sar-113461	Sorex araneus	81.89	0.00e+00	726.00
IUUC-Ssc-115349	Sus scrofa	94.02	0.00e+00	833.00
IUUC-Tgu-116876	Taeniopygia guttata	88.94	0.00e+00	783.00
IUUC-Tru-118306	Takifugu rubripes	67.60	4.00e-174	604.00
IUUC-Tsy-118901	Tarsius syrichta	85.67	7.00e-154	536.00
IUUC-Tni-120120	Tetraodon nigroviridis	68.43	1.00e-178	619.00
IUUC-Xtr-132925	Xenopus tropicalis	80.29	0.00e+00	741.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence