iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054177

Ensembl Protein ID

ENSLAFP00000008775.3

UniProt Accession

G3T5P7; G3T5P7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBASH3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000010479.3	ENSLAFT00000010480.3	ENSLAFP00000008775.3
ENSLAFG00000010479.3	ENSLAFT00000028466.1	ENSLAFP00000022229.1
ENSLAFG00000010479.3	ENSLAFT00000025713.1	ENSLAFP00000026472.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	9.20e-09	35.5	28	65
UBD/SH3	1.20e-21	76.8	244	307

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           ++l+ l +MGF+r +a++aL+++ + +++aA+++L+++
   Q: 28   SALDLLLSMGFPRARAQKALASTgGRSVQAACDWLFSH 65
           67999*******************************97 PP

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++e++qv+y+y++qnddeL+l  Gd++++   e+++++egW++g++ ++g++Gl+Pen+++k++
   Q: 244  NHETLQVIYPYSPQNDDELELVPGDFIFMSpmEQTSTSEGWIYGTSLTTGCSGLLPENYITKAD 307
           6899*********************************************************987 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAAREELYSK VTPRRHRQQR PGTIKHGSAL DLLLSMGFPR ARAQKALAST GGRSVQAACD 60
WLFSHVGDPF LDDPLPREYV LYLRPTGPLA QTLSDFWQQS KQICGKNKAH NIFPHITLCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGCGC GAGAGGAACT GTACAGCAAA GTCACCCCCC GGCGGCACCG CCAGCAGCGC 60
CCAGGCACCA TCAAGCATGG ATCGGCGCTG GACCTGCTCC TCTCCATGGG CTTCCCCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009097--cNuc_Pdiesterase
IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR001452--SH3_domain
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50002--SH3
PS50030--UBA

Pfam

PF00300--His_Phos_1
PF14604--SH3_9
PF00627--UBA

SMART

SM00326--SH3
SM00165--UBA

Gene Ontology

GO:0004725--F:protein tyrosine phosphatase activity
GO:0045779--P:negative regulation of bone resorption
GO:0045671--P:negative regulation of osteoclast differentiation
GO:0090331--P:negative regulation of platelet aggregation
GO:0006469--P:negative regulation of protein kinase activity
GO:0009968--P:negative regulation of signal transduction
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002126	Ailuropoda melanoleuca	96.06	0.00e+00	1257.00
IUUC-Apl-004080	Anas platyrhynchos	89.61	0.00e+00	1092.00
IUUC-Aca-004828	Anolis carolinensis	83.44	0.00e+00	1034.00
IUUC-Ame-011030	Astyanax mexicanus	73.80	0.00e+00	826.00
IUUC-Bta-012370	Bos taurus	96.64	0.00e+00	1185.00
IUUC-Bci-013728	Botrytis cinerea	28.14	6.00e-10	58.20
IUUC-Cel-018530	Caenorhabditis elegans	39.69	7.00e-51	193.00
IUUC-Cja-018758	Callithrix jacchus	97.34	0.00e+00	1250.00
IUUC-Cfa-020544	Canis familiaris	95.93	0.00e+00	1009.00
IUUC-Cpo-022044	Cavia porcellus	96.81	0.00e+00	1184.00
IUUC-Csa-024169	Chlorocebus sabaeus	97.18	0.00e+00	1248.00
IUUC-Cho-024498	Choloepus hoffmanni	79.50	0.00e+00	893.00
IUUC-Cin-025372	Ciona intestinalis	40.84	5.00e-57	215.00
IUUC-Csv-026379	Ciona savignyi	43.87	1.00e-74	273.00
IUUC-Cgl-026592	Colletotrichum gloeosporioides	29.08	1.00e-08	53.50
IUUC-Cme-027186	Cyanidioschyzon merolae	28.09	2.00e-08	52.80
IUUC-Dre-027539	Danio rerio	73.29	0.00e+00	995.00
IUUC-Dno-029808	Dasypus novemcinctus	96.04	0.00e+00	741.00
IUUC-Dor-030582	Dipodomys ordii	79.62	0.00e+00	1000.00
IUUC-Dme-032201	Drosophila melanogaster	38.79	1.00e-64	241.00
IUUC-Ete-032740	Echinops telfairi	78.37	0.00e+00	1019.00
IUUC-Eca-033743	Equus caballus	97.18	0.00e+00	1203.00
IUUC-Eeu-034505	Erinaceus europaeus	83.93	0.00e+00	689.00
IUUC-Fca-036519	Felis catus	96.08	0.00e+00	1264.00
IUUC-Fal-037295	Ficedula albicollis	87.81	0.00e+00	1090.00
IUUC-Gmo-038650	Gadus morhua	71.65	0.00e+00	920.00
IUUC-Gga-040179	Gallus gallus	89.20	0.00e+00	1173.00
IUUC-Gac-042180	Gasterosteus aculeatus	71.34	0.00e+00	934.00
IUUC-Ggo-044581	Gorilla gorilla	97.49	0.00e+00	1251.00
IUUC-Hsa-046526	Homo sapiens	97.34	0.00e+00	1251.00
IUUC-Itr-048502	Ictidomys tridecemlineatus	95.27	0.00e+00	640.00
IUUC-Lch-049576	Latimeria chalumnae	79.90	0.00e+00	1007.00
IUUC-Loc-051854	Lepisosteus oculatus	79.36	0.00e+00	934.00
IUUC-Mcc-055185	Macaca mulatta	97.34	0.00e+00	1250.00
IUUC-Meu-056216	Macropus eugenii	91.60	0.00e+00	1063.00
IUUC-Mga-059564	Meleagris gallopavo	89.60	0.00e+00	1095.00
IUUC-Mmr-060934	Microcebus murinus	97.34	0.00e+00	1251.00
IUUC-Mdo-062955	Monodelphis domestica	94.38	0.00e+00	1218.00
IUUC-Mmu-063301	Mus musculus	96.55	0.00e+00	1269.00
IUUC-Mpu-066416	Mustela putorius furo	96.39	0.00e+00	1265.00
IUUC-Mlu-067833	Myotis lucifugus	87.39	0.00e+00	1014.00
IUUC-Nle-069367	Nomascus leucogenys	96.87	0.00e+00	1244.00
IUUC-Opr-070879	Ochotona princeps	84.38	0.00e+00	746.00
IUUC-Ont-072540	Oreochromis niloticus	74.45	0.00e+00	953.00
IUUC-Oan-073124	Ornithorhynchus anatinus	89.33	0.00e+00	882.00
IUUC-Ocu-074796	Oryctolagus cuniculus	96.55	0.00e+00	1242.00
IUUC-Ola-087253	Oryzias latipes	72.83	0.00e+00	951.00
IUUC-Oga-088406	Otolemur garnettii	91.71	0.00e+00	1121.00
IUUC-Oar-090262	Ovis aries	96.55	0.00e+00	1243.00
IUUC-Ptr-091014	Pan troglodytes	97.49	0.00e+00	1251.00
IUUC-Pan-092684	Papio anubis	97.34	0.00e+00	1250.00
IUUC-Psi-093541	Pelodiscus sinensis	89.67	0.00e+00	1173.00
IUUC-Pma-094108	Petromyzon marinus	55.82	2.00e-153	535.00
IUUC-Pfo-097119	Poecilia formosa	72.43	0.00e+00	909.00
IUUC-Pab-097724	Pongo abelii	95.62	0.00e+00	1217.00
IUUC-Pca-100645	Procavia capensis	76.99	0.00e+00	730.00
IUUC-Pva-102322	Pteropus vampyrus	96.47	0.00e+00	1180.00
IUUC-Rno-105148	Rattus norvegicus	95.92	0.00e+00	1261.00
IUUC-Sha-106673	Sarcophilus harrisii	86.93	0.00e+00	1071.00
IUUC-Ssl-108385	Sclerotinia sclerotiorum	30.95	1.00e-08	53.50
IUUC-Sar-113746	Sorex araneus	76.11	3.00e-98	351.00
IUUC-Ssc-116425	Sus scrofa	96.52	0.00e+00	1201.00
IUUC-Tgu-116520	Taeniopygia guttata	87.79	0.00e+00	1134.00
IUUC-Tru-117750	Takifugu rubripes	67.32	0.00e+00	889.00
IUUC-Tsy-118975	Tarsius syrichta	96.30	0.00e+00	1154.00
IUUC-Tni-119830	Tetraodon nigroviridis	72.41	0.00e+00	913.00
IUUC-Tbe-127895	Tupaia belangeri	95.92	1.00e-131	463.00
IUUC-Ttr-129103	Tursiops truncatus	96.08	0.00e+00	1263.00
IUUC-Vpa-130720	Vicugna pacos	97.45	6.00e-113	401.00
IUUC-Xtr-132314	Xenopus tropicalis	83.44	0.00e+00	1110.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence