iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009791

Ensembl Protein ID

CAK36885

UniProt Accession

A2Q888; A2Q888_ASPNC

Genbank Protein ID

CAK36885.1

Protein Name

Aspergillus niger contig An01c0110, genomic contig

Genbank Nucleotide ID

AM269958

Gene Name

An01g03470

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An01g03470	CAK36885	CAK36885

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.10e-78	262.0	727	1066

Active Site

Position(s)	Description	Evidence
1035	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfykll 100
           ++++kk l++ef+gEeg+d+gG+ +e++ ll++e+++p  glf y+++++++ + np  +    e  + F ++G+llg+a++++ +ld+ l+++ +k+l
   Q: 727  QEEIKKGLRIEFLGEEGVDAGGLRKEWFLLLVREVFDPHHGLFIYDDDSRYC-YFNPYCF----ESSEQFFLVGVLLGLAIYNSTILDIALPPFAFKKL 820
           67899****************************************9998888.6699888....5678888**************************** PP
   S: 101  lgk...........klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegike 188
           l             k+sl+dl+e+ p l+k l  ++++ e d+ e+ ++  f ++ + +get ++ L+ gGen pVtn+N++e+v+l+v++ l + +++
   Q: 821  LAAaplssitrpmyKCSLDDLAELRPALAKGLRALLDY-EGDVAET-FCYDFVAQVDRYGETVSVPLCAGGENRPVTNANRREFVDLYVHFLLDTAVTR 917
           999888888888888***********************.6788886.**************************************************** PP
   S: 189  qveafreGfneviplellslFteeelellicGe.eeidvedlkketky...kggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk 283
           q+e f++Gf +v+  + lslF++ee+ell+ G+ e +dv +l++ ++y    +   e++p+++wFw+++e+ + + ++++L FvTgs+r+P+ G  +l+
   Q: 918  QFEPFKRGFFTVCGGNALSLFRPEEIELLVRGSdEPLDVASLRAVATYdnwSNARPETEPVVRWFWDFFEQTQPQAQRKILSFVTGSDRIPAMGATSLS 1016
           *********************************999**********99554445568999*************************************** PP
   S: 284  prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            rl+++ +  +++r+P++ TCfn+L L +Y++ e+l+++L  A+ +++gF+l
   Q: 1017 IRLVCLGD--ETSRFPTARTCFNQLGLYRYETREKLERMLWDAVLNGEGFGL 1066
           **999999..89**************************************98 PP

Organism

Aspergillus niger

Protein Sequence
(Fasta)

MTSGKCMVCN STVRWPRNLK VFRCTECLTV NDLEPFVDSG KAGGNGLSGS DGKAPTPAVP 60
RKAMPLSIER TKTILDDCLS RYLQQLLAPQ QQNSTPENYS GKYLDVAQDE NLSQSPTQSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTTCGG GAAAGTGCAT GGTTTGTAAC AGCACAGTGC GTTGGCCGCG GAATCTCAAG 60
GTTTTTCGGT GCACGGAATG TTTGACTGTA AATGACTTGG AGCCATTTGT GGACTCTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	35.80	3.00e-100	357.00
IUUC-Atr-003144	Amborella trichopoda	39.18	1.00e-85	308.00
IUUC-Apl-003589	Anas platyrhynchos	35.21	2.00e-92	331.00
IUUC-Aca-004350	Anolis carolinensis	40.71	3.00e-94	337.00
IUUC-Ago-007908	Ashbya gossypii	32.21	2.00e-95	342.00
IUUC-Acl-008288	Aspergillus clavatus	68.29	0.00e+00	1399.00
IUUC-Afl-008402	Aspergillus flavus	81.94	0.00e+00	1126.00
IUUC-Afu-008762	Aspergillus fumigatus	68.11	0.00e+00	1427.00
IUUC-Ani-009176	Aspergillus nidulans	75.25	0.00e+00	942.00
IUUC-Aor-009921	Aspergillus oryzae	83.31	0.00e+00	1031.00
IUUC-Ate-010295	Aspergillus terreus	72.37	0.00e+00	1389.00
IUUC-Ame-011166	Astyanax mexicanus	37.56	6.00e-81	293.00
IUUC-Bgr-011981	Blumeria graminis	48.57	0.00e+00	951.00
IUUC-Bta-012945	Bos taurus	41.59	1.00e-97	349.00
IUUC-Bci-013697	Botrytis cinerea	54.23	0.00e+00	860.00
IUUC-Cel-018150	Caenorhabditis elegans	31.88	2.00e-55	209.00
IUUC-Cja-019263	Callithrix jacchus	40.49	1.00e-94	338.00
IUUC-Cfa-020486	Canis familiaris	35.87	5.00e-101	360.00
IUUC-Cpo-021755	Cavia porcellus	35.37	2.00e-100	358.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	41.92	6.00e-59	219.00
IUUC-Csa-023814	Chlorocebus sabaeus	40.59	1.00e-84	305.00
IUUC-Cho-025059	Choloepus hoffmanni	35.25	2.00e-68	252.00
IUUC-Cin-025643	Ciona intestinalis	31.25	1.00e-69	256.00
IUUC-Csv-026282	Ciona savignyi	30.31	6.00e-64	237.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	49.33	0.00e+00	821.00
IUUC-Cme-027151	Cyanidioschyzon merolae	38.04	4.00e-77	281.00
IUUC-Dre-028551	Danio rerio	40.31	2.00e-93	335.00
IUUC-Dno-029497	Dasypus novemcinctus	40.93	3.00e-96	344.00
IUUC-Dor-030158	Dipodomys ordii	33.26	2.00e-68	252.00
IUUC-Dse-031239	Dothistroma septosporum	48.84	0.00e+00	806.00
IUUC-Dme-032103	Drosophila melanogaster	36.47	1.00e-70	259.00
IUUC-Ete-032902	Echinops telfairi	33.22	6.00e-90	323.00
IUUC-Eca-033678	Equus caballus	36.03	2.00e-101	361.00
IUUC-Eeu-035109	Erinaceus europaeus	36.22	1.00e-69	256.00
IUUC-Fca-035590	Felis catus	36.20	2.00e-102	365.00
IUUC-Fal-037123	Ficedula albicollis	33.50	3.00e-82	298.00
IUUC-Fox-037941	Fusarium oxysporum	46.27	0.00e+00	905.00
IUUC-Fso-038388	Fusarium solani	46.56	0.00e+00	898.00
IUUC-Gmo-039553	Gadus morhua	40.00	8.00e-82	296.00
IUUC-Ggr-040110	Gaeumannomyces graminis	45.76	0.00e+00	863.00
IUUC-Gga-040406	Gallus gallus	35.04	4.00e-95	340.00
IUUC-Gac-042141	Gasterosteus aculeatus	34.65	2.00e-92	331.00
IUUC-Ggo-045504	Gorilla gorilla	39.82	3.00e-94	338.00
IUUC-Hsa-045786	Homo sapiens	39.82	2.00e-94	338.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	36.89	6.00e-75	273.00
IUUC-Kpa-049152	Komagataella pastoris	34.90	2.00e-94	338.00
IUUC-Lch-049824	Latimeria chalumnae	40.29	5.00e-81	293.00
IUUC-Loc-052173	Lepisosteus oculatus	35.54	7.00e-102	363.00
IUUC-Laf-054017	Loxodonta africana	40.49	1.00e-95	342.00
IUUC-Mcc-055713	Macaca mulatta	40.49	2.00e-94	338.00
IUUC-Meu-056061	Macropus eugenii	37.11	1.00e-75	276.00
IUUC-Mor-057045	Magnaporthe oryzae	45.45	0.00e+00	874.00
IUUC-Mla-059187	Melampsora laricipopulina	42.60	3.00e-93	333.00
IUUC-Mga-059884	Meleagris gallopavo	40.47	3.00e-87	314.00
IUUC-Mmr-061344	Microcebus murinus	35.70	1.00e-100	359.00
IUUC-Mdo-062653	Monodelphis domestica	41.15	1.00e-96	345.00
IUUC-Mmu-063775	Mus musculus	41.50	9.00e-98	349.00
IUUC-Mpu-066069	Mustela putorius furo	36.03	1.00e-101	362.00
IUUC-Mlu-067925	Myotis lucifugus	41.81	8.00e-99	352.00
IUUC-Nfi-068439	Neosartorya fischeri	65.69	0.00e+00	1354.00
IUUC-Ncr-068903	Neurospora crassa	45.95	0.00e+00	843.00
IUUC-Nle-070046	Nomascus leucogenys	34.98	3.00e-97	347.00
IUUC-Opr-070891	Ochotona princeps	36.52	4.00e-60	224.00
IUUC-Ont-072126	Oreochromis niloticus	35.04	4.00e-98	350.00
IUUC-Oan-072933	Ornithorhynchus anatinus	40.93	5.00e-95	340.00
IUUC-Ocu-073800	Oryctolagus cuniculus	41.15	3.00e-95	340.00
IUUC-Ola-086988	Oryzias latipes	34.82	2.00e-95	341.00
IUUC-Oga-088117	Otolemur garnettii	40.93	9.00e-95	339.00
IUUC-Oar-089371	Ovis aries	41.59	2.00e-97	348.00
IUUC-Ptr-090551	Pan troglodytes	39.82	3.00e-94	337.00
IUUC-Pan-092067	Papio anubis	40.49	1.00e-94	338.00
IUUC-Psi-092963	Pelodiscus sinensis	40.84	2.00e-92	331.00
IUUC-Pma-094643	Petromyzon marinus	33.95	1.00e-81	296.00
IUUC-Ppa-095354	Physcomitrella patens	38.91	5.00e-87	314.00
IUUC-Pfo-096562	Poecilia formosa	34.21	9.00e-95	339.00
IUUC-Pab-098680	Pongo abelii	40.27	1.00e-94	339.00
IUUC-Pca-100869	Procavia capensis	36.67	2.00e-76	278.00
IUUC-Pva-102219	Pteropus vampyrus	38.86	6.00e-78	283.00
IUUC-Pgr-103315	Puccinia graminis	37.38	4.00e-105	374.00
IUUC-Ptt-103736	Puccinia triticina	42.77	3.00e-101	361.00
IUUC-Rno-105270	Rattus norvegicus	41.59	1.00e-98	352.00
IUUC-Sce-106306	Saccharomyces cerevisiae	33.49	1.00e-84	306.00
IUUC-Sha-106819	Sarcophilus harrisii	32.81	2.00e-101	362.00
IUUC-Sja-107974	Schizosaccharomyces japonicus	36.80	4.00e-60	224.00
IUUC-Spo-108271	Schizosaccharomyces pombe	37.74	6.00e-116	410.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	49.20	0.00e+00	946.00
IUUC-Smo-108858	Selaginella moellendorffii	41.70	5.00e-89	320.00
IUUC-Sar-113134	Sorex araneus	36.97	2.00e-80	291.00
IUUC-Ssc-115441	Sus scrofa	41.50	3.00e-97	347.00
IUUC-Tgu-117166	Taeniopygia guttata	35.04	8.00e-92	329.00
IUUC-Tru-118368	Takifugu rubripes	36.91	2.00e-79	288.00
IUUC-Tsy-118898	Tarsius syrichta	36.54	3.00e-76	277.00
IUUC-Tni-120143	Tetraodon nigroviridis	37.14	1.00e-79	289.00
IUUC-Tre-122108	Trichoderma reesei	45.84	0.00e+00	855.00
IUUC-Tvi-122644	Trichoderma virens	46.21	0.00e+00	863.00
IUUC-Tme-127004	Tuber melanosporum	57.65	0.00e+00	806.00
IUUC-Tbe-127292	Tupaia belangeri	33.93	1.00e-69	255.00
IUUC-Ttr-128352	Tursiops truncatus	38.72	1.00e-86	312.00
IUUC-Vda-129969	Verticillium dahliae	50.56	0.00e+00	800.00
IUUC-Vpa-130448	Vicugna pacos	33.61	1.00e-68	253.00
IUUC-Xtr-132594	Xenopus tropicalis	40.04	7.00e-84	303.00
IUUC-Xma-134157	Xiphophorus maculatus	33.75	5.00e-85	306.00
IUUC-Yli-134470	Yarrowia lipolytica	34.93	2.00e-106	379.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence