iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000016782.10	ENSDART00000146990.1	ENSDARP00000118265.1
ENSDARG00000016782.10	ENSDART00000006657.10	ENSDARP00000002767.10

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.50e-102	343.2	4158	4459

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrll 88
           ++d+k+rl++ f+gEeg+d+gG+ re++  +s+e++np++ lf++s++d+ t+++np+s + np+hl++F+f+Gr+++ka++d+rll
   Q: 4158 PEDMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHC-NPNHLSYFKFVGRVVAKAVYDNRLL 4243
           689********************************************************86.99*********************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
           ++ +++sfyk++lgk++ + d+e+ d  +++ l +++en   d+++lg +ltfs++ +++g +++++Lk +G+ni Vt+eNk+eYv+
   Q: 4244 ECYFTRSFYKHILGKSVRYTDMESEDYPFFQGLVYLLEN---DVSTLGYELTFSTEVQEFGVCEVRDLKANGANILVTEENKKEYVH 4327
           *************************************99...********************************************* PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           lv++++++  i++q++af eGf+e+ip++l+s+Fte+elelli+G ++id++dlk++t+y++ y+++s +iqwFw++l++f++ +r+
   Q: 4328 LVCQMKMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKANTEYHK-YQSSSIQIQWFWRALRSFDQADRA 4413
           ************************************************************66.************************ PP
   S: 263  afLqFvTgssrlPlgGfaelk....prlfvirk.dasddrlPssnT 303
           +fLqFvTg+s++Pl+Gfa+l+     ++f+i++ d+s+drlPs++T
   Q: 4414 KFLQFVTGTSKVPLQGFAALEgmngIQKFQIHRdDRSTDRLPSAHT 4459
           *********************99998999999988899*******9 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

KLVTMKVDRS KLKKTPTEAP ADCRTLIEKL KGCSDEQLLL ELQQIKTWNI GKCELYHWVD 60
LLDRFDGILC DAGQTVENMS WLLVCDRPEN GQLKALLLAV LNFTALLIEY SFSRHLYSSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCTGCTG TAAGATGGAG AAGTTATGTT GAGGCGCAAC CGAGGTAAGG GCTTAAATTA 60
GTCTTTGTCT GTTTGATGGA GACGTCTGTT GTTCACTCTA CGTGATCTTT AACAGTACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr

PROSITE

PS50237--HECT
PS50030--UBA
PS50918--WWE

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF02825--WWE

SMART

SM00119--HECTc
SM00678--WWE

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	49.72	1.00e-98	357.00
IUUC-Aml-001684	Ailuropoda melanoleuca	82.73	0.00e+00	3735.00
IUUC-Atr-002582	Amborella trichopoda	48.18	1.00e-112	403.00
IUUC-Apl-003729	Anas platyrhynchos	91.29	0.00e+00	682.00
IUUC-Aca-005263	Anolis carolinensis	83.12	0.00e+00	3760.00
IUUC-Aly-006083	Arabidopsis lyrata	49.64	1.00e-110	396.00
IUUC-Ath-007472	Arabidopsis thaliana	49.64	9.00e-111	397.00
IUUC-Ago-008005	Ashbya gossypii	45.51	1.00e-115	412.00
IUUC-Acl-008254	Aspergillus clavatus	52.04	1.00e-120	430.00
IUUC-Afl-008712	Aspergillus flavus	45.23	2.00e-122	433.00
IUUC-Afu-009022	Aspergillus fumigatus	45.23	5.00e-121	431.00
IUUC-Ani-009412	Aspergillus nidulans	46.04	3.00e-122	435.00
IUUC-Ang-009771	Aspergillus niger	44.83	3.00e-121	432.00
IUUC-Aor-010186	Aspergillus oryzae	45.23	1.00e-122	435.00
IUUC-Ate-010253	Aspergillus terreus	45.12	3.00e-121	431.00
IUUC-Ame-011067	Astyanax mexicanus	88.68	0.00e+00	4309.00
IUUC-Bgr-012043	Blumeria graminis	45.82	2.00e-124	442.00
IUUC-Bta-012813	Bos taurus	82.12	0.00e+00	3763.00
IUUC-Bci-013995	Botrytis cinerea	45.01	9.00e-124	440.00
IUUC-Bdi-014884	Brachypodium distachyon	50.51	5.00e-113	404.00
IUUC-Bra-016637	Brassica rapa	48.56	3.00e-108	389.00
IUUC-Cel-018179	Caenorhabditis elegans	59.67	1.00e-167	586.00
IUUC-Cja-018741	Callithrix jacchus	82.45	0.00e+00	3750.00
IUUC-Cfa-020083	Canis familiaris	82.87	0.00e+00	3763.00
IUUC-Cpo-021923	Cavia porcellus	82.61	0.00e+00	3724.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	47.50	6.00e-106	377.00
IUUC-Csa-023853	Chlorocebus sabaeus	82.40	0.00e+00	3751.00
IUUC-Cho-024718	Choloepus hoffmanni	96.79	0.00e+00	726.00
IUUC-Cin-025627	Ciona intestinalis	41.25	0.00e+00	1828.00
IUUC-Csv-025824	Ciona savignyi	47.30	0.00e+00	1395.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	51.68	4.00e-122	435.00
IUUC-Cne-027095	Cryptococcus neoformans	40.33	3.00e-93	338.00
IUUC-Cme-027267	Cyanidioschyzon merolae	47.80	1.00e-99	358.00
IUUC-Dno-029680	Dasypus novemcinctus	81.96	0.00e+00	3682.00
IUUC-Dor-030902	Dipodomys ordii	85.28	0.00e+00	1082.00
IUUC-Dse-031197	Dothistroma septosporum	45.18	7.00e-122	434.00
IUUC-Dme-032122	Drosophila melanogaster	68.24	0.00e+00	731.00
IUUC-Ete-032690	Echinops telfairi	70.39	0.00e+00	944.00
IUUC-Eca-033915	Equus caballus	81.78	0.00e+00	3705.00
IUUC-Eeu-034963	Erinaceus europaeus	80.89	0.00e+00	2595.00
IUUC-Fca-035824	Felis catus	82.58	0.00e+00	3746.00
IUUC-Fox-037756	Fusarium oxysporum	45.34	2.00e-122	436.00
IUUC-Fso-038464	Fusarium solani	52.93	1.00e-122	436.00
IUUC-Gmo-039073	Gadus morhua	89.96	0.00e+00	3925.00
IUUC-Ggr-039946	Gaeumannomyces graminis	44.62	1.00e-121	433.00
IUUC-Gga-040309	Gallus gallus	95.67	6.00e-165	573.00
IUUC-Gac-042430	Gasterosteus aculeatus	89.91	0.00e+00	4048.00
IUUC-Gma-043129	Glycine max	45.96	8.00e-112	400.00
IUUC-Ggo-044785	Gorilla gorilla	82.36	0.00e+00	3719.00
IUUC-Hsa-046879	Homo sapiens	82.40	0.00e+00	3726.00
IUUC-Hvu-047697	Hordeum vulgare	50.51	3.00e-113	405.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	93.28	0.00e+00	985.00
IUUC-Kpa-049228	Komagataella pastoris	46.64	4.00e-123	437.00
IUUC-Lch-050252	Latimeria chalumnae	80.68	0.00e+00	3112.00
IUUC-Lpe-051550	Leersia perrieri	49.38	9.00e-113	403.00
IUUC-Loc-052472	Lepisosteus oculatus	87.94	0.00e+00	3875.00
IUUC-Lma-053159	Leptosphaeria maculans	45.18	4.00e-123	438.00
IUUC-Laf-054154	Loxodonta africana	81.85	0.00e+00	3698.00
IUUC-Mcc-055085	Macaca mulatta	82.90	0.00e+00	3739.00
IUUC-Meu-056727	Macropus eugenii	86.09	0.00e+00	1779.00
IUUC-Mor-057201	Magnaporthe oryzae	45.86	2.00e-122	436.00
IUUC-Mpo-057597	Magnaporthe poae	44.76	3.00e-120	428.00
IUUC-Mtr-058273	Medicago truncatula	51.52	1.00e-113	406.00
IUUC-Mla-058888	Melampsora laricipopulina	47.01	7.00e-99	353.00
IUUC-Mvi-060320	Microbotryum violaceum	47.81	5.00e-108	387.00
IUUC-Mmr-060820	Microcebus murinus	82.13	0.00e+00	3742.00
IUUC-Mdo-062930	Monodelphis domestica	82.94	0.00e+00	3749.00
IUUC-Mmu-063601	Mus musculus	82.24	0.00e+00	3685.00
IUUC-Mac-065229	Musa acuminata	50.51	3.00e-111	398.00
IUUC-Mpu-066653	Mustela putorius furo	80.83	0.00e+00	3610.00
IUUC-Mlu-067418	Myotis lucifugus	82.29	0.00e+00	3804.00
IUUC-Nfi-068278	Neosartorya fischeri	45.44	1.00e-121	432.00
IUUC-Ncr-068813	Neurospora crassa	45.44	1.00e-123	439.00
IUUC-Nle-069418	Nomascus leucogenys	82.31	0.00e+00	3707.00
IUUC-Opr-070187	Ochotona princeps	77.22	0.00e+00	791.00
IUUC-Ont-071300	Oreochromis niloticus	85.48	0.00e+00	5126.00
IUUC-Oan-073046	Ornithorhynchus anatinus	77.56	0.00e+00	3760.00
IUUC-Ocu-074178	Oryctolagus cuniculus	82.29	0.00e+00	3786.00
IUUC-Oba-075757	Oryza barthii	49.38	4.00e-113	404.00
IUUC-Obr-076553	Oryza brachyantha	49.88	6.00e-113	404.00
IUUC-Ogl-077520	Oryza glaberrima	49.38	4.00e-113	404.00
IUUC-Ogu-078278	Oryza glumaepatula	49.38	4.00e-113	404.00
IUUC-Oin-079767	Oryza indica	49.38	6.00e-113	404.00
IUUC-Olo-080380	Oryza longistaminata	48.90	3.00e-111	398.00
IUUC-Ome-081925	Oryza meridionalis	48.90	3.00e-111	398.00
IUUC-Oni-082619	Oryza nivara	49.38	5.00e-113	404.00
IUUC-Opu-083684	Oryza punctata	48.90	2.00e-111	399.00
IUUC-Oru-084501	Oryza rufipogon	49.38	5.00e-113	404.00
IUUC-Osa-086251	Oryza sativa	49.38	1.00e-111	397.00
IUUC-Ola-087437	Oryzias latipes	89.12	0.00e+00	2237.00
IUUC-Olu-087813	Ostreococcus lucimarinus	48.92	2.00e-102	365.00
IUUC-Oga-088903	Otolemur garnettii	82.20	0.00e+00	3729.00
IUUC-Oar-090210	Ovis aries	82.61	0.00e+00	3763.00
IUUC-Ptr-090502	Pan troglodytes	81.59	0.00e+00	2815.00
IUUC-Pan-092368	Papio anubis	81.79	0.00e+00	3761.00
IUUC-Pma-094246	Petromyzon marinus	72.16	0.00e+00	1245.00
IUUC-Pno-094871	Phaeosphaeria nodorum	50.12	5.00e-121	431.00
IUUC-Ppa-095657	Physcomitrella patens	49.64	7.00e-111	397.00
IUUC-Pfo-096232	Poecilia formosa	86.15	0.00e+00	6628.00
IUUC-Pab-098583	Pongo abelii	82.40	0.00e+00	3725.00
IUUC-Pop-099613	Populus trichocarpa	51.52	1.00e-113	405.00
IUUC-Pca-100310	Procavia capensis	72.77	0.00e+00	1461.00
IUUC-Ppe-102109	Prunus persica	51.01	1.00e-112	403.00
IUUC-Pva-102116	Pteropus vampyrus	82.12	0.00e+00	3777.00
IUUC-Pgr-103465	Puccinia graminis	42.30	5.00e-110	394.00
IUUC-Ptt-103813	Puccinia triticina	40.04	1.00e-97	353.00
IUUC-Pte-104018	Pyrenophora teres	50.24	4.00e-120	427.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	50.24	1.00e-119	426.00
IUUC-Rno-105889	Rattus norvegicus	75.49	0.00e+00	3308.00
IUUC-Sce-106449	Saccharomyces cerevisiae	43.06	2.00e-111	399.00
IUUC-Sha-106961	Sarcophilus harrisii	82.17	0.00e+00	3733.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	43.18	3.00e-111	398.00
IUUC-Spo-108024	Schizosaccharomyces pombe	44.29	8.00e-113	403.00
IUUC-Smo-109428	Selaginella moellendorffii	49.41	1.00e-115	412.00
IUUC-Sit-110598	Setaria italica	50.76	4.00e-113	404.00
IUUC-Sly-111285	Solanum lycopersicum	50.00	2.00e-113	405.00
IUUC-Sar-113291	Sorex araneus	76.52	0.00e+00	2269.00
IUUC-Sbi-114042	Sorghum bicolor	50.25	2.00e-112	402.00
IUUC-Sre-114958	Sporisorium reilianum	53.83	4.00e-121	428.00
IUUC-Ssc-115754	Sus scrofa	82.28	0.00e+00	3734.00
IUUC-Tru-118570	Takifugu rubripes	84.41	0.00e+00	6526.00
IUUC-Tsy-119159	Tarsius syrichta	82.97	0.00e+00	1904.00
IUUC-Tni-120836	Tetraodon nigroviridis	76.79	0.00e+00	2423.00
IUUC-Tca-121646	Theobroma cacao	50.12	2.00e-112	402.00
IUUC-Tre-121909	Trichoderma reesei	52.54	3.00e-120	428.00
IUUC-Tvi-122370	Trichoderma virens	52.54	2.00e-120	429.00
IUUC-Tae-125214	Triticum aestivum	49.50	3.00e-111	397.00
IUUC-Tme-127172	Tuber melanosporum	45.73	6.00e-123	437.00
IUUC-Tbe-127506	Tupaia belangeri	73.09	0.00e+00	1151.00
IUUC-Ttr-129253	Tursiops truncatus	72.01	0.00e+00	1739.00
IUUC-Uma-129355	Ustilago maydis	46.86	2.00e-121	429.00
IUUC-Vda-129886	Verticillium dahliae	45.56	3.00e-124	441.00
IUUC-Vpa-130708	Vicugna pacos	80.77	0.00e+00	3276.00
IUUC-Vvi-131170	Vitis vinifera	49.28	4.00e-112	400.00
IUUC-Xtr-132123	Xenopus tropicalis	80.76	0.00e+00	3629.00
IUUC-Xma-133869	Xiphophorus maculatus	86.72	0.00e+00	2695.00
IUUC-Yli-134657	Yarrowia lipolytica	43.76	3.00e-113	405.00
IUUC-Zma-135570	Zea mays	50.25	1.00e-112	403.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence