iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000002806.2	ENSLACT00000026102.1	ENSLACP00000023304.1
ENSLACG00000002806.2	ENSLACT00000003164.1	ENSLACP00000003134.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/Josephin	1.80e-77	259.3	2	176

Active Site

Position(s)	Description	Evidence
14	N/A	{ECO:0000256\|PROSITE-ProRule:PRU00331}
115		{ECO:0000256\|PROSITE-ProRule:PRU00331}
130		{ECO:0000256\|PROSITE-ProRule:PRU00331}

Domain Profile

DUB/Josephin

   S: 12   esiyhekqrrelCalhalnnvlqdelfsreeldeiakrldeeerlqPskslldtGnydvnvisaalkvlGleavwfdkrrelqklaldn 100
           +siyhekqr+elCa+ha+nn++q+++fs+e +dei+krl+++ r++P++sll+ Gnydvnvi+aal+ + ++avw+dkrr l+ lald+
   Q: 2    DSIYHEKQRLELCAIHAVNNIFQEKVFSKEGADEICKRLAPDVRVNPHRSLLGMGNYDVNVIMAALQSRSFAAVWWDKRRSLELLALDR 90
           79*************************************************************************************** PP
   S: 101  vlgfilnlpsslslgllklplkkqhWvtvrkvgkayynldsklkaPeligdetelrkflakllqqkyselllvvkeevedkesdqr 186
           ++gfiln+ps++ lg ++lp++++hW++vr+v++ yynldsklk+P lig+e+ lrkfl+++  q+ +e+llvv+ +ve+ +s++ 
   Q: 91   IQGFILNIPSNVMLGFVSLPIRRKHWIAVRQVQGFYYNLDSKLKSPALIGGEEDLRKFLKNQVSQEPCEMLLVVHSDVEEDGSWLN 176
           ************************************************************************************75 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

ADSIYHEKQR LELCAIHAVN NIFQEKVFSK EGADEICKRL APDVRVNPHR SLLGMGNYDV 60
NVIMAALQSR SFAAVWWDKR RSLELLALDR IQGFILNIPS NVMLGFVSLP IRRKHWIAVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCCATGGT AACGCGGCCA TGTCACAAGA GAGTCAAATA CAACCGGAAA GATTTACAAC 60
AAAACAAAAA CAGCCAGGGA GGAAGAGGAA ATATAGGATC GCGGCGCAGC GGCTGAAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR006155--Josephin

PROSITE

PS50957--JOSEPHIN

Pfam

PF02099--Josephin

SMART

SM01246--Josephin

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001650	Ailuropoda melanoleuca	63.58	3.00e-51	194.00
IUUC-Aca-004833	Anolis carolinensis	66.48	2.00e-69	254.00
IUUC-Ame-010835	Astyanax mexicanus	70.39	8.00e-75	272.00
IUUC-Bta-012918	Bos taurus	65.70	7.00e-52	196.00
IUUC-Cel-018568	Caenorhabditis elegans	45.51	2.00e-39	154.00
IUUC-Cja-019837	Callithrix jacchus	64.53	4.00e-51	193.00
IUUC-Cfa-021001	Canis familiaris	63.58	2.00e-51	194.00
IUUC-Cpo-021340	Cavia porcellus	64.53	3.00e-51	194.00
IUUC-Csa-023069	Chlorocebus sabaeus	64.52	8.00e-51	192.00
IUUC-Cin-025666	Ciona intestinalis	62.32	2.00e-51	195.00
IUUC-Cme-027180	Cyanidioschyzon merolae	36.51	4.00e-07	47.80
IUUC-Dre-028459	Danio rerio	69.27	6.00e-74	269.00
IUUC-Dno-029569	Dasypus novemcinctus	64.16	1.00e-51	195.00
IUUC-Dor-030570	Dipodomys ordii	65.32	3.00e-50	191.00
IUUC-Dme-032124	Drosophila melanogaster	47.34	1.00e-41	162.00
IUUC-Fca-036089	Felis catus	63.58	3.00e-51	194.00
IUUC-Gmo-038493	Gadus morhua	69.36	7.00e-71	259.00
IUUC-Gac-041579	Gasterosteus aculeatus	72.25	3.00e-74	270.00
IUUC-Ggo-045508	Gorilla gorilla	64.74	4.00e-52	197.00
IUUC-Hsa-046522	Homo sapiens	64.74	3.00e-52	197.00
IUUC-Itr-048074	Ictidomys tridecemlineatus	64.53	3.00e-51	194.00
IUUC-Mcc-054840	Macaca mulatta	64.53	2.00e-51	194.00
IUUC-Meu-056539	Macropus eugenii	65.32	2.00e-60	224.00
IUUC-Mtr-058745	Medicago truncatula	32.95	6.00e-26	109.00
IUUC-Mmu-063463	Mus musculus	65.52	7.00e-52	196.00
IUUC-Mac-065631	Musa acuminata	40.83	3.00e-26	113.00
IUUC-Mpu-066337	Mustela putorius furo	63.43	1.00e-51	196.00
IUUC-Nle-069739	Nomascus leucogenys	63.95	1.00e-50	192.00
IUUC-Ont-072050	Oreochromis niloticus	72.83	2.00e-70	257.00
IUUC-Ola-086805	Oryzias latipes	71.68	2.00e-73	267.00
IUUC-Oga-088741	Otolemur garnettii	64.16	7.00e-46	176.00
IUUC-Oar-089548	Ovis aries	65.12	1.00e-51	195.00
IUUC-Ptr-091101	Pan troglodytes	57.80	2.00e-52	198.00
IUUC-Pan-092144	Papio anubis	64.53	2.00e-51	194.00
IUUC-Ppa-095444	Physcomitrella patens	31.77	7.00e-25	106.00
IUUC-Pfo-097459	Poecilia formosa	73.41	2.00e-75	274.00
IUUC-Pca-100200	Procavia capensis	57.47	9.00e-50	189.00
IUUC-Pva-102585	Pteropus vampyrus	64.74	6.00e-52	196.00
IUUC-Rno-105654	Rattus norvegicus	64.94	1.00e-51	195.00
IUUC-Smo-109138	Selaginella moellendorffii	40.00	5.00e-18	83.60
IUUC-Stu-112215	Solanum tuberosum	35.20	2.00e-26	111.00
IUUC-Ssc-115298	Sus scrofa	65.12	2.00e-52	197.00
IUUC-Tru-118437	Takifugu rubripes	68.72	5.00e-73	266.00
IUUC-Tni-120715	Tetraodon nigroviridis	72.25	2.00e-69	254.00
IUUC-Tur-126618	Triticum urartu	35.25	4.00e-15	74.30
IUUC-Xtr-132462	Xenopus tropicalis	62.78	3.00e-66	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence