iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107987

Ensembl Protein ID

EEB09699

UniProt Accession

B6K845; B6K845_SCHJY

Genbank Protein ID

EEB09699.1

Protein Name

Transcriptional corepressor Tup12

Genbank Nucleotide ID

KE651167

Gene Name

SJAG_04921

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_04921	EEB09699	EEB09699

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-48	157.9	446	478
UBD/Beta-Prp	8.20e-79	262.9	275	574

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gH++sv+++af +d  +l+sGs D+tik+W+l 
   Q: 446  GHQESVYSVAFsPDgLTLASGSLDNTIKLWELQ 478
           8***********99888**************85 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheae......vtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           +h+svi+cvkfs d++llatg+ ++   v++v+tg+ll  l++ ++e      v++v fs dgk+l+tg eDr i++wd+ +    + l+ghe++++sl++
   Q: 275  EHTSVICCVKFSHDGKLLATGC-NRAALVFSVETGQLLTHLQEESSEkegdlyVRSVAFSADGKYLATGVEDRQIRIWDIAQKRVHRLLSGHEQEIYSLDY 374
           69********************.88888*********9999888888899*************************************************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgt 203
           s++g++lvsGs drt+ +w +etgq    +l   dg+ ++v+++pd++++++GslD+++r+W++ +g+ll++l g h++svys++f+++g  l+sgsld+t
   Q: 375  SRDGKYLVSGSGDRTVYLWSVETGQRKL-VLHTDDGI-TTVAFSPDSQYIAAGSLDKVIRIWSI-NGTLLEQLVG-HQESVYSVAFSPDGLTLASGSLDNT 471
           ***************************9.99888876.56788899****************99.*********9.************************* PP
   S: 204  vklwdlq............tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniw 292
           +klw+lq             g c +t++gh++ ++sv++sp+++++vsgs+D+++++W+    +   tlq+hn+svisva+ s+++n +++gs+d +++iw
   Q: 472  IKLWELQsaagvptnaikpGGICKKTFTGHKNYILSVALSPDGKWIVSGSKDRTVQFWNPNGFQSQATLQGHNNSVISVAM-SPTGNCFATGSGDLRARIW 571
           *********99999999988999**********************************************************.******************* PP
   S: 293  klk 295
           +++
   Q: 572  SYQ 574
           *96 PP

Organism

Schizosaccharomyces japonicus

Protein Sequence
(Fasta)

MATSSVTSRL NELLEALRTE LDTFLKQNLQ GDIHPDDYGY KLVTSQIQEI HRIKKAIMEL 60
EMQHVKIKEG YEEEISQLKN ELQKRRRDST PAANAKTAST PSQSSQPSFT MASTNTRSNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTGCGCGT AACCCCTGCA ATTAAACACC ACGTGAACGT CGAGGCTGCG CCAACTTTAC 60
GTTTTTTTCC AAGTTTTTGG TTAAAGACGG TGAAACAGGT CCTTAATACC TAATGGCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR013890--Tscrpt_rep_Tup1_N
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08581--Tup_N
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0000790--C:nuclear chromatin
GO:0043156--P:chromatin remodeling in response to cation stress
GO:0006342--P:chromatin silencing
GO:0045014--P:negative regulation of transcription by glucose
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007787	Ashbya gossypii	36.68	5.00e-99	352.00
IUUC-Bgr-012206	Blumeria graminis	56.33	2.00e-109	387.00
IUUC-Bci-013662	Botrytis cinerea	57.06	7.00e-117	412.00
IUUC-Cgl-026593	Colletotrichum gloeosporioides	59.52	4.00e-119	419.00
IUUC-Ggr-039887	Gaeumannomyces graminis	59.76	1.00e-120	424.00
IUUC-Mpo-057414	Magnaporthe poae	59.76	3.00e-120	423.00
IUUC-Mvi-060368	Microbotryum violaceum	46.70	5.00e-98	350.00
IUUC-Ncr-068753	Neurospora crassa	58.81	1.00e-119	421.00
IUUC-Ocu-074101	Oryctolagus cuniculus	31.71	1.00e-38	152.00
IUUC-Ptt-103788	Puccinia triticina	40.05	1.00e-72	265.00
IUUC-Spo-108210	Schizosaccharomyces pombe	54.30	1.00e-173	601.00
IUUC-Tni-120713	Tetraodon nigroviridis	30.52	2.00e-30	125.00
IUUC-Tme-127064	Tuber melanosporum	54.12	1.00e-120	424.00
IUUC-Vda-129718	Verticillium dahliae	58.56	2.00e-116	410.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence