iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048018

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01098030

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000002701.2	ENSSTOT00000002698.2	ENSSTOP00000002414.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.70e-07	29.2	268	309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e f  kd  ++lpC+H+fh+ C+  w         + +CP C+
   Q: 268  CAVCIENFkvKDVIRILPCKHIFHRICIDPW------LLDHRTCPMCK 309
           ********9988899****************......9999******6 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MAWPRRATAG IRARGALALL ALAWCAPGAQ SRALEWYSAV VGLEYVDPQT NLTVRSVSES 60
GRFGDSSPQE DAQGLVGVPL APGGDPEGCA PGTRFLVPTP RGQGPAPWVA LVARGGCTFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGGC CGCGGCGGGC TACGGCCGGG ATCCGAGCCC GCGGCGCGCT GGCGCTGCTG 60
GCCTTGGCCT GGTGCGCGCC GGGGGCCCAG AGCCGAGCGC TCGAGTGGTA CTCGGCGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001968	Ailuropoda melanoleuca	80.70	2.00e-170	591.00
IUUC-Apl-004109	Anas platyrhynchos	71.80	2.00e-101	361.00
IUUC-Bta-012340	Bos taurus	79.78	2.00e-166	577.00
IUUC-Cja-019566	Callithrix jacchus	79.31	7.00e-172	596.00
IUUC-Cfa-020289	Canis familiaris	82.99	3.00e-111	393.00
IUUC-Cpo-021916	Cavia porcellus	66.67	3.00e-73	267.00
IUUC-Csa-024084	Chlorocebus sabaeus	80.38	2.00e-170	591.00
IUUC-Cho-024305	Choloepus hoffmanni	79.17	2.00e-135	474.00
IUUC-Cin-025124	Ciona intestinalis	37.29	2.00e-52	199.00
IUUC-Csv-026229	Ciona savignyi	39.66	2.00e-56	212.00
IUUC-Cne-026985	Cryptococcus neoformans	29.63	3.00e-11	63.90
IUUC-Dno-030098	Dasypus novemcinctus	80.55	0.00e+00	625.00
IUUC-Dor-030620	Dipodomys ordii	76.29	4.00e-146	510.00
IUUC-Ete-032306	Echinops telfairi	82.49	2.00e-173	601.00
IUUC-Fca-035950	Felis catus	81.85	3.00e-120	423.00
IUUC-Fal-037429	Ficedula albicollis	67.02	1.00e-136	479.00
IUUC-Fox-038011	Fusarium oxysporum	39.74	4.00e-14	72.80
IUUC-Fso-038141	Fusarium solani	39.53	5.00e-15	75.50
IUUC-Gga-041201	Gallus gallus	65.45	2.00e-132	465.00
IUUC-Ggo-045429	Gorilla gorilla	79.83	5.00e-166	576.00
IUUC-Hsa-046191	Homo sapiens	79.10	5.00e-175	606.00
IUUC-Kpa-049389	Komagataella pastoris	33.78	3.00e-11	62.40
IUUC-Lch-049498	Latimeria chalumnae	60.86	5.00e-130	457.00
IUUC-Laf-054239	Loxodonta africana	70.36	7.00e-137	479.00
IUUC-Meu-056382	Macropus eugenii	72.65	4.00e-152	530.00
IUUC-Mor-056917	Magnaporthe oryzae	43.94	3.00e-13	69.70
IUUC-Mga-059435	Meleagris gallopavo	71.81	2.00e-68	251.00
IUUC-Mmr-061513	Microcebus murinus	78.95	1.00e-164	572.00
IUUC-Mdo-063028	Monodelphis domestica	72.78	8.00e-155	539.00
IUUC-Mmu-063545	Mus musculus	79.05	1.00e-154	538.00
IUUC-Mpu-066370	Mustela putorius furo	79.57	1.00e-167	582.00
IUUC-Mlu-067271	Myotis lucifugus	76.51	7.00e-138	483.00
IUUC-Nle-069207	Nomascus leucogenys	79.84	7.00e-174	602.00
IUUC-Opr-070704	Ochotona princeps	72.87	2.00e-101	361.00
IUUC-Oan-072837	Ornithorhynchus anatinus	66.23	2.00e-140	491.00
IUUC-Ocu-074671	Oryctolagus cuniculus	79.72	6.00e-125	439.00
IUUC-Oga-089083	Otolemur garnettii	77.56	3.00e-168	584.00
IUUC-Oar-089254	Ovis aries	79.84	5.00e-111	393.00
IUUC-Ptr-090940	Pan troglodytes	80.11	2.00e-171	594.00
IUUC-Pan-092636	Papio anubis	79.84	7.00e-170	589.00
IUUC-Psi-093435	Pelodiscus sinensis	75.21	8.00e-98	349.00
IUUC-Pab-098525	Pongo abelii	79.73	4.00e-168	583.00
IUUC-Pva-102395	Pteropus vampyrus	80.38	2.00e-171	594.00
IUUC-Pgr-103263	Puccinia graminis	37.36	3.00e-12	67.00
IUUC-Rno-105789	Rattus norvegicus	80.11	5.00e-154	536.00
IUUC-Sha-107305	Sarcophilus harrisii	72.61	1.00e-98	352.00
IUUC-Ssc-115598	Sus scrofa	77.98	2.00e-162	565.00
IUUC-Tgu-116463	Taeniopygia guttata	66.48	2.00e-130	458.00
IUUC-Tsy-118915	Tarsius syrichta	76.61	2.00e-106	378.00
IUUC-Tme-126970	Tuber melanosporum	49.06	7.00e-13	68.60
IUUC-Tbe-127906	Tupaia belangeri	83.62	1.00e-84	305.00
IUUC-Xtr-131821	Xenopus tropicalis	63.37	4.00e-129	453.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence