iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-092993

Ensembl Protein ID

ENSPSIP00000012161.1

UniProt Accession

K7FVV1; K7FVV1_PELSI

Genbank Protein ID

ENSPSIP00000012161

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01200841

Gene Name

USP12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000010921.1	ENSPSIT00000012219.1	ENSPSIP00000012161.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.80e-98	329.2	33	362

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re +l  +k++      + +k++ll++l++lf+++   k+k +++ p+++++ l+ke+e f++y
   Q: 33   FGLVNFGNTCYCNSVLQALYFCRPFREKVLA-YKSQ------PRKKENLLTCLADLFHSIAtqKKKVGVIPPKKFITRLRKENELFDNY 114
           6******************************.4444......456789************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l++   ++k+e+++ +  + s ++e+++ +  +++++++Fqg+l+++++cl+c+++ss++e+fldls++v
   Q: 115  MQQDAHEFLNYLLNTIADILQE---ERKQEKQNGRLPNGSIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDV 200
           ********************44...444444455555566668888999999************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL+ f+++e+l++e kyyce+c++kqea k++k+kklP +L lhLkRf++  + ++ +k++ +v fpleL l  f+
   Q: 201  EQNT-----SITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRL--FN 282
           ****.....9**********************************************************************66665..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts +   + ++ Y+L+avv+H G +++ GHY+a+vk+ ++ WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 283  TSGDA-TNPDRMYDLVAVVIHCGsGPNRGHYIAIVKS-HDFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 362
           77444.4469***************************.555*******************999*****************97 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

ILKVRCFIFQ GANASALEKE IGPEQFPVNE HYFGLVNFGN TCYCNSVLQA LYFCRPFREK 60
VLAYKSQPRK KENLLTCLAD LFHSIATQKK KVGVIPPKKF ITRLRKENEL FDNYMQQDAH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATTAAAAG TACGTTGTTT TATTTTCCAG GGCGCCAATG CCTCAGCTTT AGAGAAAGAG 60
ATTGGTCCAG AACAGTTCCC AGTCAATGAG CACTATTTTG GTTTAGTTAA TGTAAGTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000193	Aegilops tauschii	58.79	5.00e-124	437.00
IUUC-Aml-001964	Ailuropoda melanoleuca	99.15	0.00e+00	738.00
IUUC-Apl-003411	Anas platyrhynchos	98.59	0.00e+00	730.00
IUUC-Aca-005212	Anolis carolinensis	95.60	0.00e+00	731.00
IUUC-Ago-007871	Ashbya gossypii	39.25	1.00e-49	191.00
IUUC-Acl-008239	Aspergillus clavatus	48.67	2.00e-77	283.00
IUUC-Afl-008602	Aspergillus flavus	49.83	8.00e-80	291.00
IUUC-Afu-008816	Aspergillus fumigatus	49.16	5.00e-78	285.00
IUUC-Ang-009703	Aspergillus niger	48.82	8.00e-80	291.00
IUUC-Aor-009901	Aspergillus oryzae	49.83	6.00e-80	291.00
IUUC-Ate-010431	Aspergillus terreus	50.17	6.00e-78	285.00
IUUC-Ame-011015	Astyanax mexicanus	90.68	0.00e+00	700.00
IUUC-Bgr-012071	Blumeria graminis	43.38	6.00e-75	275.00
IUUC-Bta-012981	Bos taurus	96.15	0.00e+00	731.00
IUUC-Bci-013837	Botrytis cinerea	40.87	2.00e-73	270.00
IUUC-Cja-018831	Callithrix jacchus	99.15	0.00e+00	739.00
IUUC-Cfa-020534	Canis familiaris	98.87	0.00e+00	738.00
IUUC-Cpo-021703	Cavia porcellus	99.15	0.00e+00	740.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	54.37	2.00e-98	351.00
IUUC-Csa-023604	Chlorocebus sabaeus	99.07	0.00e+00	674.00
IUUC-Cho-024902	Choloepus hoffmanni	82.49	1.00e-171	594.00
IUUC-Cin-025659	Ciona intestinalis	56.50	5.00e-130	457.00
IUUC-Cgl-026611	Colletotrichum gloeosporioides	43.28	1.00e-75	277.00
IUUC-Dre-027845	Danio rerio	91.23	0.00e+00	705.00
IUUC-Dno-029460	Dasypus novemcinctus	98.59	0.00e+00	737.00
IUUC-Dor-030972	Dipodomys ordii	98.82	1.00e-152	531.00
IUUC-Dse-031470	Dothistroma septosporum	48.54	4.00e-77	282.00
IUUC-Ete-033125	Echinops telfairi	77.89	2.00e-132	464.00
IUUC-Eca-033439	Equus caballus	99.15	0.00e+00	738.00
IUUC-Fca-035524	Felis catus	98.59	0.00e+00	734.00
IUUC-Fal-036833	Ficedula albicollis	97.46	0.00e+00	726.00
IUUC-Fox-037682	Fusarium oxysporum	43.05	3.00e-73	269.00
IUUC-Fso-038299	Fusarium solani	37.59	1.00e-74	274.00
IUUC-Gmo-038763	Gadus morhua	90.98	0.00e+00	704.00
IUUC-Gga-041151	Gallus gallus	96.15	0.00e+00	731.00
IUUC-Gac-041967	Gasterosteus aculeatus	91.26	0.00e+00	706.00
IUUC-Hsa-045700	Homo sapiens	99.15	0.00e+00	739.00
IUUC-Hvu-047692	Hordeum vulgare	58.49	1.00e-122	432.00
IUUC-Itr-049082	Ictidomys tridecemlineatus	99.15	0.00e+00	738.00
IUUC-Lch-050435	Latimeria chalumnae	97.46	0.00e+00	711.00
IUUC-Loc-051968	Lepisosteus oculatus	93.41	0.00e+00	722.00
IUUC-Lma-053300	Leptosphaeria maculans	46.79	2.00e-78	286.00
IUUC-Laf-053887	Loxodonta africana	99.15	0.00e+00	739.00
IUUC-Mcc-055701	Macaca mulatta	99.15	0.00e+00	739.00
IUUC-Mor-057072	Magnaporthe oryzae	43.65	1.00e-75	277.00
IUUC-Mga-059195	Meleagris gallopavo	98.59	0.00e+00	729.00
IUUC-Mmr-060751	Microcebus murinus	99.15	0.00e+00	739.00
IUUC-Mdo-062735	Monodelphis domestica	96.38	0.00e+00	729.00
IUUC-Mmu-063263	Mus musculus	98.31	0.00e+00	733.00
IUUC-Mlu-068128	Myotis lucifugus	99.15	0.00e+00	738.00
IUUC-Nfi-068611	Neosartorya fischeri	49.16	4.00e-78	285.00
IUUC-Ncr-068699	Neurospora crassa	44.30	5.00e-75	275.00
IUUC-Nle-069767	Nomascus leucogenys	99.15	0.00e+00	738.00
IUUC-Ont-072658	Oreochromis niloticus	91.53	0.00e+00	708.00
IUUC-Oan-073372	Ornithorhynchus anatinus	97.75	0.00e+00	731.00
IUUC-Ocu-074322	Oryctolagus cuniculus	98.60	0.00e+00	736.00
IUUC-Ola-087418	Oryzias latipes	91.53	0.00e+00	708.00
IUUC-Oga-088298	Otolemur garnettii	99.15	0.00e+00	739.00
IUUC-Oar-090269	Ovis aries	98.03	0.00e+00	729.00
IUUC-Ptr-090467	Pan troglodytes	99.15	0.00e+00	739.00
IUUC-Pan-092437	Papio anubis	98.87	0.00e+00	736.00
IUUC-Pno-095044	Phaeosphaeria nodorum	47.85	1.00e-78	287.00
IUUC-Pfo-097052	Poecilia formosa	91.53	0.00e+00	708.00
IUUC-Pab-097797	Pongo abelii	99.15	0.00e+00	739.00
IUUC-Pca-100835	Procavia capensis	90.52	3.00e-174	603.00
IUUC-Pgr-103306	Puccinia graminis	54.30	4.00e-96	346.00
IUUC-Pyt-104709	Pyrenophora triticirepentis	47.56	4.00e-78	285.00
IUUC-Rno-106060	Rattus norvegicus	97.74	0.00e+00	728.00
IUUC-Sce-106196	Saccharomyces cerevisiae	39.13	3.00e-56	213.00
IUUC-Sha-107087	Sarcophilus harrisii	99.15	0.00e+00	739.00
IUUC-Sja-107684	Schizosaccharomyces japonicus	45.58	1.00e-67	250.00
IUUC-Spo-108095	Schizosaccharomyces pombe	46.39	3.00e-76	279.00
IUUC-Sar-113216	Sorex araneus	98.59	0.00e+00	729.00
IUUC-Ssc-116321	Sus scrofa	98.31	0.00e+00	732.00
IUUC-Tgu-117482	Taeniopygia guttata	94.78	0.00e+00	707.00
IUUC-Tru-118613	Takifugu rubripes	91.53	0.00e+00	707.00
IUUC-Tsy-119520	Tarsius syrichta	88.24	1.00e-131	461.00
IUUC-Tni-120293	Tetraodon nigroviridis	91.53	0.00e+00	707.00
IUUC-Tre-122226	Trichoderma reesei	45.03	9.00e-77	281.00
IUUC-Tvi-122330	Trichoderma virens	45.21	3.00e-76	279.00
IUUC-Tae-124807	Triticum aestivum	59.07	1.00e-124	439.00
IUUC-Tur-126563	Triticum urartu	59.07	7.00e-125	439.00
IUUC-Tbe-127783	Tupaia belangeri	98.02	0.00e+00	718.00
IUUC-Ttr-129083	Tursiops truncatus	98.87	0.00e+00	738.00
IUUC-Vda-129736	Verticillium dahliae	38.76	2.00e-58	220.00
IUUC-Vpa-130391	Vicugna pacos	94.07	0.00e+00	688.00
IUUC-Xtr-132464	Xenopus tropicalis	98.87	0.00e+00	711.00
IUUC-Xma-133475	Xiphophorus maculatus	91.53	0.00e+00	708.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence