iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096937

Ensembl Protein ID

ENSPFOP00000016446.2

UniProt Accession

A0A087YEJ3; A0A087YEJ3_POEFO

Genbank Protein ID

ENSPFOP00000016446

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01013069

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000016342.2	ENSPFOT00000016468.2	ENSPFOP00000016446.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.50e-136	455.1	536	868

Active Site

Position(s)	Description	Evidence
837	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dl++rl++ f gEegld+gGv+re+++lls+e+ np+++lf+y  +d+++lq+np+s++ np+hlk+F+f+Gr++++al++g+++d+
   Q: 536  PQDLRRRLWIIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYI-NPDHLKYFKFIGRFIAMALFHGKFIDT 623
           5899********************************************************9.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            +s +fyk++l+k+l l+dle++dpe+y+sl +ik+n   +iee+gl++ fsv++eilge++++eLkp+G nipVt++NkeeY++lv+e
   Q: 624  GFSLPFYKRILNKPLALKDLESIDPEFYNSLIWIKDN---NIEECGLEMFFSVDKEILGEVSTHELKPDGGNIPVTEDNKEEYIRLVAE 709
           ***********************************99...9************************************************ PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +rl +g++eq++af eGfnev+p++ l++F+++ele+++cG++eid+ d++++t y++ y ++s++i wFw++++e+++e+r ++LqFv
   Q: 710  WRLSRGVEEQTQAFFEGFNEVLPQQYLQYFDAKELEVMLCGMQEIDLVDWQRNTIYRH-YARSSKQILWFWQFVKEMDNEKRMRLLQFV 797
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tg++rlP+gGfa+l+    p++f+i+k +++++lP+s+TCfn+L+LP+Y+s+e+lkekL++Aieet+gF++
   Q: 798  TGTCRLPVGGFADLMgsngPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLMFAIEETEGFGQ 868
           *********************************************************************96 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MKAQLQVTVL SAKLKENKKN WFGPSPYVEV AVDGESKRTE KCNNTHSPKW KQALTVIVTP 60
VSKLIFRVWS HQTLKADILL GMATLDIGTV LKANDLKLCE VVQTLQLCFD RDPQDIVGDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGAAATTTT ATTTATTTAT TTATTTGTTT GTGTATATTT TATTTAGTGA TGCACTATTT 60
TATTCTGAAA GGCATTAAGC GGAAATGTGG AATTTAGCTA GTGATACAGA AGTCCCTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010601	Astyanax mexicanus	93.33	0.00e+00	1170.00
IUUC-Bta-012782	Bos taurus	90.23	0.00e+00	1120.00
IUUC-Cja-018899	Callithrix jacchus	89.04	0.00e+00	1128.00
IUUC-Cne-026849	Cryptococcus neoformans	48.60	3.00e-160	559.00
IUUC-Dre-028809	Danio rerio	93.46	0.00e+00	1160.00
IUUC-Eeu-034716	Erinaceus europaeus	84.93	0.00e+00	828.00
IUUC-Gmo-038596	Gadus morhua	85.69	0.00e+00	1058.00
IUUC-Gac-041520	Gasterosteus aculeatus	93.89	0.00e+00	1189.00
IUUC-Hsa-046564	Homo sapiens	89.38	0.00e+00	1139.00
IUUC-Itr-048918	Ictidomys tridecemlineatus	88.53	0.00e+00	1125.00
IUUC-Lch-050454	Latimeria chalumnae	74.01	0.00e+00	1310.00
IUUC-Mmu-063375	Mus musculus	89.21	0.00e+00	1133.00
IUUC-Opr-070585	Ochotona princeps	88.53	0.00e+00	1119.00
IUUC-Ont-071798	Oreochromis niloticus	96.75	0.00e+00	1207.00
IUUC-Ocu-074298	Oryctolagus cuniculus	89.21	0.00e+00	1133.00
IUUC-Ptr-090819	Pan troglodytes	88.18	0.00e+00	1100.00
IUUC-Psi-093319	Pelodiscus sinensis	72.45	0.00e+00	1253.00
IUUC-Pab-097580	Pongo abelii	80.14	0.00e+00	995.00
IUUC-Pca-100923	Procavia capensis	79.97	0.00e+00	993.00
IUUC-Sce-106289	Saccharomyces cerevisiae	48.89	5.00e-159	555.00
IUUC-Sar-113761	Sorex araneus	89.88	0.00e+00	1113.00
IUUC-Sre-114929	Sporisorium reilianum	47.08	6.00e-154	538.00
IUUC-Tgu-116632	Taeniopygia guttata	83.65	0.00e+00	1031.00
IUUC-Tru-118442	Takifugu rubripes	92.55	0.00e+00	1148.00
IUUC-Tni-120168	Tetraodon nigroviridis	95.65	0.00e+00	1130.00
IUUC-Tre-122203	Trichoderma reesei	46.36	7.00e-148	518.00
IUUC-Tbe-127756	Tupaia belangeri	77.46	0.00e+00	825.00
IUUC-Vda-129753	Verticillium dahliae	46.94	3.00e-152	532.00
IUUC-Vpa-130103	Vicugna pacos	77.05	0.00e+00	947.00
IUUC-Xma-133987	Xiphophorus maculatus	99.32	0.00e+00	1236.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence