iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Stu-112582

Ensembl Protein ID

PGSC0003DMT400021802

UniProt Accession

M1AFQ9; M1AFQ9_SOLTU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PGSC0003DMG400008462	PGSC0003DMT400021801	PGSC0003DMT400021801
PGSC0003DMG400008462	PGSC0003DMT400021802	PGSC0003DMT400021802

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.50e-93	312.6	553	884
ULD/UDP/UBQ/UBQ_Other	7.30e-09	36.6	89	162

Active Site

Position(s)	Description	Evidence
857	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           ++l+  l++ef+ Ee+++  Gv re+++l++++++np++ lf+  +nd++ ++pnp+s++ +p hl++F f Gr++++al+++  + + 
   Q: 553  ESLRGGLFMEFKSEEATGP-GVLREWFFLVCRAIFNPQNALFVACPNDRRRFFPNPASKV-DPLHLEYFSFSGRVIALALMHKIQVGIV 639
           6788899***********9.***************************************9.68************************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           + ++f+ +l gk++sl+d+ + dp ly s  +i+e++ + +++ +l ltf ++ e+lg++k++eL+p+G++++V+ +N+++Yv+l++++
   Q: 640  FDRVFFLQLSGKSISLDDIRDADPFLYSSCRQILEMDPEMVDQDTLGLTFVREVEELGSRKVVELCPNGKSTMVNSKNRKQYVELLIQH 728
           ************************************99999999********************************************* PP
   S: 181  rlkegikeqveafreGfnev.....iplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerka 263
           r+ ++i+eqv++f +Gf ++     ++++++++++ e+l+ +++G+ + ++ved+k++t y+ gy+e++p+i wFw+++  +s+e+rk 
   Q: 729  RFVTSIAEQVAHFAQGFADIittvrLQKSFFQSLDLEDLDWMLHGSeTAVSVEDWKAHTDYN-GYKESDPQISWFWKIVGCMSAEQRKV 816
           ********************5554456778999*************999************5.5************************* PP
   S: 264  fLqFvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetk 331
           +L F+T+ + lP++Gf  l  rl++++  +s+drlPss+TCf++L+ P+Y+s+++++++L + ++e  
   Q: 817  LLFFWTSIKYLPVEGFGGLASRLYIYKTRESNDRLPSSHTCFFRLCFPPYPSMDVMQDRLHIITQEHV 884
           ************************************************************98777763 PP

ULD/UDP/UBQ/UBQ_Other

   S: 2    qvtvksldgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
           q++v+ l g  +l l+ +++d+V+ + eki+  +g+p  +qrLiy+Gk L+  +tLa ++++++  + l+ +++
   Q: 89   QFFVRLLSGGnTLVLQAESTDSVKSIHEKIQFITGMPITEQRLIYRGKQLQWEQTLAGCDIQNDAGLQLVGRMR 162
           789999999999999999********************************9999**************999876 PP

Organism

Solanum tuberosum

Protein Sequence
(Fasta)

MTGVNPKRKL EDYAADEDAV SSELYLVHSA VRMRKDQSVL TSFTDSPPRH HQNNSSDSAS 60
SSPQQLPSSS SSSSSSVFTQ STRFLGRLQF FVRLLSGGNT LVLQAESTDS VKSIHEKIQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTTTCTC ACTCTCCATT TTCTCTCTCT ACACTTTCTC TCTCCTCTTC ATCTTCTTCT 60
TCTTCCTCTT GTTGTTTTCA GTTTTGATTG AGGAAAGTTT TGAACTCAGC AGAAAAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50237--HECT
PS50053--UBIQUITIN_2

Pfam

PF00632--HECT
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00119--HECTc
SM00213--UBQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

sot:102593986

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000327	Aegilops tauschii	43.76	5.00e-171	593.00
IUUC-Aml-001684	Ailuropoda melanoleuca	32.35	1.00e-56	216.00
IUUC-Atr-002891	Amborella trichopoda	45.27	0.00e+00	695.00
IUUC-Apl-003893	Anas platyrhynchos	36.09	7.00e-55	207.00
IUUC-Aca-005263	Anolis carolinensis	32.35	1.00e-56	216.00
IUUC-Aly-005570	Arabidopsis lyrata	50.99	0.00e+00	817.00
IUUC-Ath-007126	Arabidopsis thaliana	51.48	0.00e+00	825.00
IUUC-Ago-007742	Ashbya gossypii	34.08	1.00e-53	203.00
IUUC-Afl-008712	Aspergillus flavus	34.75	3.00e-56	213.00
IUUC-Ani-009412	Aspergillus nidulans	35.21	4.00e-57	217.00
IUUC-Ang-009771	Aspergillus niger	34.46	2.00e-55	212.00
IUUC-Aor-010186	Aspergillus oryzae	34.93	2.00e-52	200.00
IUUC-Ate-010253	Aspergillus terreus	34.46	7.00e-55	210.00
IUUC-Ame-011067	Astyanax mexicanus	32.68	8.00e-56	213.00
IUUC-Bta-012813	Bos taurus	32.35	1.00e-56	216.00
IUUC-Bci-013785	Botrytis cinerea	34.64	2.00e-52	199.00
IUUC-Bdi-014613	Brachypodium distachyon	42.86	0.00e+00	637.00
IUUC-Bol-016237	Brassica oleracea	47.90	0.00e+00	759.00
IUUC-Bra-017376	Brassica rapa	48.27	0.00e+00	761.00
IUUC-Cel-018179	Caenorhabditis elegans	32.32	3.00e-54	207.00
IUUC-Cja-018741	Callithrix jacchus	32.58	3.00e-57	218.00
IUUC-Cfa-020083	Canis familiaris	32.35	1.00e-56	216.00
IUUC-Cpo-021671	Cavia porcellus	35.81	1.00e-55	210.00
IUUC-Csa-023853	Chlorocebus sabaeus	32.35	1.00e-56	216.00
IUUC-Cho-024718	Choloepus hoffmanni	33.33	3.00e-56	214.00
IUUC-Dre-027770	Danio rerio	35.54	7.00e-54	204.00
IUUC-Dno-029680	Dasypus novemcinctus	32.35	1.00e-56	216.00
IUUC-Dor-030138	Dipodomys ordii	35.81	7.00e-56	211.00
IUUC-Dme-032122	Drosophila melanogaster	32.92	4.00e-55	211.00
IUUC-Ete-033145	Echinops telfairi	35.54	2.00e-54	206.00
IUUC-Eca-033915	Equus caballus	32.48	1.00e-56	216.00
IUUC-Eeu-034963	Erinaceus europaeus	32.27	2.00e-56	215.00
IUUC-Fca-035824	Felis catus	32.35	1.00e-56	216.00
IUUC-Fal-037604	Ficedula albicollis	36.36	5.00e-55	208.00
IUUC-Fox-037756	Fusarium oxysporum	34.56	1.00e-56	216.00
IUUC-Fso-038464	Fusarium solani	34.79	1.00e-56	216.00
IUUC-Gmo-039073	Gadus morhua	32.68	1.00e-55	212.00
IUUC-Gga-041276	Gallus gallus	36.36	2.00e-55	209.00
IUUC-Gac-042430	Gasterosteus aculeatus	32.68	6.00e-56	213.00
IUUC-Gma-043337	Glycine max	63.48	0.00e+00	1045.00
IUUC-Ggo-045332	Gorilla gorilla	35.81	2.00e-55	209.00
IUUC-Hsa-046879	Homo sapiens	32.35	1.00e-56	216.00
IUUC-Hvu-047734	Hordeum vulgare	45.43	0.00e+00	651.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	32.35	4.00e-57	216.00
IUUC-Kpa-049273	Komagataella pastoris	36.03	1.00e-54	206.00
IUUC-Lch-050252	Latimeria chalumnae	32.76	3.00e-55	211.00
IUUC-Lpe-051617	Leersia perrieri	43.22	7.00e-163	566.00
IUUC-Loc-052472	Lepisosteus oculatus	32.92	1.00e-56	216.00
IUUC-Lma-053159	Leptosphaeria maculans	34.93	4.00e-55	211.00
IUUC-Laf-054154	Loxodonta africana	32.35	1.00e-56	216.00
IUUC-Mcc-055085	Macaca mulatta	32.35	9.00e-57	216.00
IUUC-Mpo-057442	Magnaporthe poae	35.20	1.00e-54	207.00
IUUC-Mtr-058709	Medicago truncatula	57.83	0.00e+00	916.00
IUUC-Mga-059362	Meleagris gallopavo	34.99	2.00e-51	196.00
IUUC-Mmr-060820	Microcebus murinus	32.35	1.00e-56	216.00
IUUC-Mdo-062930	Monodelphis domestica	32.35	1.00e-56	216.00
IUUC-Mmu-063601	Mus musculus	32.35	1.00e-56	216.00
IUUC-Mac-065415	Musa acuminata	47.28	0.00e+00	694.00
IUUC-Mpu-066653	Mustela putorius furo	32.35	9.00e-57	216.00
IUUC-Mlu-067418	Myotis lucifugus	32.35	9.00e-57	216.00
IUUC-Nle-069418	Nomascus leucogenys	32.35	1.00e-56	216.00
IUUC-Opr-071044	Ochotona princeps	35.81	2.00e-55	209.00
IUUC-Ont-071300	Oreochromis niloticus	32.68	7.00e-56	213.00
IUUC-Oan-073046	Ornithorhynchus anatinus	32.43	1.00e-55	213.00
IUUC-Ocu-074178	Oryctolagus cuniculus	32.35	8.00e-57	216.00
IUUC-Oba-075190	Oryza barthii	46.97	7.00e-156	543.00
IUUC-Obr-076197	Oryza brachyantha	44.95	2.00e-171	594.00
IUUC-Ogl-077892	Oryza glaberrima	43.16	9.00e-153	533.00
IUUC-Ogu-078711	Oryza glumaepatula	44.06	3.00e-159	555.00
IUUC-Oin-079504	Oryza indica	43.04	1.00e-153	536.00
IUUC-Olo-080730	Oryza longistaminata	46.82	2.00e-155	541.00
IUUC-Ome-081851	Oryza meridionalis	43.56	1.00e-164	572.00
IUUC-Oni-082230	Oryza nivara	44.06	6.00e-159	553.00
IUUC-Opu-084015	Oryza punctata	44.57	3.00e-160	558.00
IUUC-Oru-084327	Oryza rufipogon	44.06	3.00e-159	555.00
IUUC-Osa-086148	Oryza sativa	43.04	4.00e-153	534.00
IUUC-Ola-087467	Oryzias latipes	35.26	4.00e-54	205.00
IUUC-Oga-088903	Otolemur garnettii	32.35	1.00e-56	216.00
IUUC-Oar-090210	Ovis aries	32.35	1.00e-56	216.00
IUUC-Ptr-090939	Pan troglodytes	35.81	1.00e-55	210.00
IUUC-Pan-092284	Papio anubis	35.81	1.00e-55	211.00
IUUC-Psi-093645	Pelodiscus sinensis	36.09	2.00e-55	209.00
IUUC-Pma-094364	Petromyzon marinus	35.16	2.00e-53	202.00
IUUC-Pno-094871	Phaeosphaeria nodorum	35.49	2.00e-55	211.00
IUUC-Pfo-096232	Poecilia formosa	32.68	1.00e-55	213.00
IUUC-Pab-098583	Pongo abelii	32.35	1.00e-56	216.00
IUUC-Pop-099556	Populus trichocarpa	57.35	0.00e+00	932.00
IUUC-Pca-100568	Procavia capensis	34.79	7.00e-50	191.00
IUUC-Ppe-101443	Prunus persica	59.67	0.00e+00	1051.00
IUUC-Pva-102354	Pteropus vampyrus	35.81	1.00e-55	210.00
IUUC-Pte-104018	Pyrenophora teres	35.21	6.00e-54	206.00
IUUC-Rno-105318	Rattus norvegicus	35.81	1.00e-55	210.00
IUUC-Sce-106289	Saccharomyces cerevisiae	35.47	2.00e-54	206.00
IUUC-Sha-106961	Sarcophilus harrisii	32.35	1.00e-56	216.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	34.64	1.00e-52	200.00
IUUC-Smo-109099	Selaginella moellendorffii	42.32	0.00e+00	628.00
IUUC-Sit-110651	Setaria italica	42.96	1.00e-173	602.00
IUUC-Sly-111513	Solanum lycopersicum	97.76	0.00e+00	1724.00
IUUC-Sar-113291	Sorex araneus	32.55	2.00e-55	211.00
IUUC-Sbi-114659	Sorghum bicolor	40.26	4.00e-128	451.00
IUUC-Ssc-115754	Sus scrofa	32.35	1.00e-56	216.00
IUUC-Tgu-117130	Taeniopygia guttata	36.36	3.00e-55	209.00
IUUC-Tru-118570	Takifugu rubripes	32.68	8.00e-56	213.00
IUUC-Tsy-119492	Tarsius syrichta	35.81	4.00e-54	205.00
IUUC-Tni-120836	Tetraodon nigroviridis	32.68	9.00e-56	213.00
IUUC-Tca-121392	Theobroma cacao	65.26	0.00e+00	1066.00
IUUC-Tre-121909	Trichoderma reesei	34.54	2.00e-57	218.00
IUUC-Tvi-122370	Trichoderma virens	34.26	1.00e-57	219.00
IUUC-Tae-125860	Triticum aestivum	40.41	2.00e-155	541.00
IUUC-Tur-126774	Triticum urartu	45.47	2.00e-172	598.00
IUUC-Tme-127172	Tuber melanosporum	33.18	3.00e-57	218.00
IUUC-Tbe-127793	Tupaia belangeri	31.37	4.00e-44	172.00
IUUC-Ttr-129253	Tursiops truncatus	32.35	1.00e-56	216.00
IUUC-Vpa-130708	Vicugna pacos	32.35	1.00e-56	216.00
IUUC-Vvi-131149	Vitis vinifera	64.89	0.00e+00	1088.00
IUUC-Xtr-132859	Xenopus tropicalis	36.36	4.00e-56	212.00
IUUC-Xma-133869	Xiphophorus maculatus	32.68	6.00e-56	213.00
IUUC-Zma-134807	Zea mays	41.51	1.00e-168	585.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence