iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035907

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02051825

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000013019.3	ENSFCAT00000013024.3	ENSFCAP00000012077.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.00e-104	350.6	747	1084

Active Site

Position(s)	Description	Evidence
1052	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal++
   Q: 747  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPSPAAHMLVGD-SFARHYYFLGRMLGKALYE 832
           689**********99**9*********************************************9965.99***************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++ +f+++llg+  ++++++l+++dpe+yk+l ++k++ e d+eelgl++t+   ++ lge++++eLk gG++ipVt +N
   Q: 833  NMLVELPFAGFFLSKLLGTsaDVDIHHLASLDPEVYKNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKFGGKDIPVTSAN 916
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i++++ afr+G+ +v++le+l++F+++e+++li+G    i++edlk++t+y ggy++d+p+i+ Fw+v+e+
   Q: 917  RIAYIHLVADYRLNRQIRQHCLAFRQGLANVLNLEWLRMFDQQEIQVLISGAqVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEG 1003
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe+  ++ l++kLlyAie ++gFels
   Q: 1004 FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS 1084
           ****************************88.*****99999**************************************985 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLGGAS RKEEKASLLH RTQEERRKRE EERRRLKNAI IIQSFIRGYR 60
DRKQQHSIQR SAFDRYASAS QSGGTFSIAS GPNLTLLVRR LLFFYKQNED SKRLIWMYQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNAGTGT CGCCGCCTCC CCCACCCGAG GGCAGGCCGG GCAGGCAGAG 60
CCCCCAGGGC GGGCTCGGGG TCGCTCCCCG CTGCGGCGTA ATCCTCCCCG CAGGCGACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

KEGG

fca:101085362

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	95.15	0.00e+00	1982.00
IUUC-Apl-003731	Anas platyrhynchos	89.40	0.00e+00	1916.00
IUUC-Aca-005248	Anolis carolinensis	87.82	0.00e+00	1917.00
IUUC-Aly-005768	Arabidopsis lyrata	34.74	5.00e-109	389.00
IUUC-Ath-006576	Arabidopsis thaliana	34.10	1.00e-109	390.00
IUUC-Ago-007748	Ashbya gossypii	41.90	3.00e-77	283.00
IUUC-Acl-008158	Aspergillus clavatus	38.09	5.00e-76	280.00
IUUC-Afl-008398	Aspergillus flavus	34.02	8.00e-78	285.00
IUUC-Afu-008937	Aspergillus fumigatus	35.05	1.00e-80	295.00
IUUC-Ani-009252	Aspergillus nidulans	38.51	7.00e-81	295.00
IUUC-Ang-009773	Aspergillus niger	34.19	1.00e-78	288.00
IUUC-Aor-009940	Aspergillus oryzae	34.02	9.00e-78	285.00
IUUC-Ate-010395	Aspergillus terreus	39.02	2.00e-77	284.00
IUUC-Ame-010769	Astyanax mexicanus	62.66	0.00e+00	1028.00
IUUC-Bgr-012269	Blumeria graminis	37.77	5.00e-75	275.00
IUUC-Bta-012841	Bos taurus	91.61	0.00e+00	1935.00
IUUC-Bci-013743	Botrytis cinerea	29.79	3.00e-86	313.00
IUUC-Bol-015390	Brassica oleracea	34.01	4.00e-101	362.00
IUUC-Bra-016853	Brassica rapa	34.88	3.00e-108	386.00
IUUC-Cel-018638	Caenorhabditis elegans	39.61	1.00e-89	324.00
IUUC-Cja-019743	Callithrix jacchus	90.99	0.00e+00	1917.00
IUUC-Cfa-021031	Canis familiaris	96.14	0.00e+00	2029.00
IUUC-Cpo-022401	Cavia porcellus	90.68	0.00e+00	1932.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	43.73	3.00e-83	301.00
IUUC-Csa-024107	Chlorocebus sabaeus	94.00	0.00e+00	1979.00
IUUC-Cho-024750	Choloepus hoffmanni	82.50	0.00e+00	802.00
IUUC-Cin-025432	Ciona intestinalis	44.88	1.00e-97	349.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	33.80	2.00e-86	314.00
IUUC-Cne-026841	Cryptococcus neoformans	37.13	1.00e-95	344.00
IUUC-Cme-027265	Cyanidioschyzon merolae	46.62	8.00e-102	364.00
IUUC-Dre-028196	Danio rerio	77.12	0.00e+00	1603.00
IUUC-Dno-029024	Dasypus novemcinctus	93.27	0.00e+00	1988.00
IUUC-Dor-030483	Dipodomys ordii	89.82	0.00e+00	676.00
IUUC-Dse-031416	Dothistroma septosporum	33.56	8.00e-78	285.00
IUUC-Dme-031946	Drosophila melanogaster	37.29	0.00e+00	679.00
IUUC-Ete-032240	Echinops telfairi	79.57	3.00e-172	598.00
IUUC-Eca-033828	Equus caballus	93.97	0.00e+00	1963.00
IUUC-Eeu-034604	Erinaceus europaeus	85.00	1.00e-126	447.00
IUUC-Fal-037389	Ficedula albicollis	89.39	0.00e+00	1931.00
IUUC-Fox-037788	Fusarium oxysporum	37.14	3.00e-92	333.00
IUUC-Fso-038088	Fusarium solani	36.20	6.00e-89	322.00
IUUC-Gmo-039254	Gadus morhua	66.37	0.00e+00	1231.00
IUUC-Ggr-039941	Gaeumannomyces graminis	34.08	1.00e-83	305.00
IUUC-Gga-040310	Gallus gallus	89.39	0.00e+00	1929.00
IUUC-Gac-042054	Gasterosteus aculeatus	68.63	0.00e+00	1284.00
IUUC-Gma-042836	Glycine max	34.10	1.00e-101	364.00
IUUC-Ggo-045031	Gorilla gorilla	94.37	0.00e+00	1987.00
IUUC-Hsa-045880	Homo sapiens	94.28	0.00e+00	1986.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	82.51	0.00e+00	671.00
IUUC-Kpa-049307	Komagataella pastoris	36.28	3.00e-64	239.00
IUUC-Lch-050403	Latimeria chalumnae	81.08	0.00e+00	1666.00
IUUC-Loc-052218	Lepisosteus oculatus	81.31	0.00e+00	1705.00
IUUC-Lma-053096	Leptosphaeria maculans	38.44	7.00e-80	292.00
IUUC-Laf-054162	Loxodonta africana	88.93	0.00e+00	1675.00
IUUC-Mcc-055127	Macaca mulatta	94.10	0.00e+00	1981.00
IUUC-Meu-056187	Macropus eugenii	82.17	4.00e-105	376.00
IUUC-Mor-057021	Magnaporthe oryzae	34.38	6.00e-78	286.00
IUUC-Mpo-057570	Magnaporthe poae	36.46	6.00e-76	279.00
IUUC-Mtr-058154	Medicago truncatula	35.52	9.00e-105	375.00
IUUC-Mla-059124	Melampsora laricipopulina	48.03	4.00e-102	364.00
IUUC-Mga-059581	Meleagris gallopavo	89.15	0.00e+00	1914.00
IUUC-Mvi-060445	Microbotryum violaceum	37.54	3.00e-104	373.00
IUUC-Mmr-061360	Microcebus murinus	89.41	0.00e+00	1835.00
IUUC-Mdo-062194	Monodelphis domestica	86.17	0.00e+00	1916.00
IUUC-Mmu-064189	Mus musculus	90.22	0.00e+00	1952.00
IUUC-Mac-065275	Musa acuminata	48.90	9.00e-108	384.00
IUUC-Mpu-066439	Mustela putorius furo	93.35	0.00e+00	1946.00
IUUC-Mlu-068228	Myotis lucifugus	88.27	0.00e+00	1892.00
IUUC-Nfi-068280	Neosartorya fischeri	38.64	1.00e-78	288.00
IUUC-Ncr-068869	Neurospora crassa	35.79	1.00e-81	298.00
IUUC-Nle-069687	Nomascus leucogenys	92.66	0.00e+00	1925.00
IUUC-Opr-070592	Ochotona princeps	75.65	6.00e-124	438.00
IUUC-Ont-071836	Oreochromis niloticus	77.42	0.00e+00	1640.00
IUUC-Oan-072800	Ornithorhynchus anatinus	89.85	0.00e+00	1933.00
IUUC-Ocu-074587	Oryctolagus cuniculus	94.00	0.00e+00	1990.00
IUUC-Ola-087209	Oryzias latipes	76.94	0.00e+00	1612.00
IUUC-Olu-087699	Ostreococcus lucimarinus	42.32	8.00e-86	310.00
IUUC-Oga-088776	Otolemur garnettii	87.08	0.00e+00	1792.00
IUUC-Oar-089441	Ovis aries	90.88	0.00e+00	1916.00
IUUC-Ptr-091273	Pan troglodytes	94.19	0.00e+00	1982.00
IUUC-Pan-091981	Papio anubis	94.00	0.00e+00	1981.00
IUUC-Psi-093203	Pelodiscus sinensis	87.98	0.00e+00	1657.00
IUUC-Pma-094738	Petromyzon marinus	65.42	0.00e+00	1340.00
IUUC-Pno-095132	Phaeosphaeria nodorum	29.38	3.00e-59	223.00
IUUC-Ppa-095682	Physcomitrella patens	35.58	5.00e-112	399.00
IUUC-Pfo-097511	Poecilia formosa	77.35	0.00e+00	1652.00
IUUC-Pab-098634	Pongo abelii	90.23	0.00e+00	1901.00
IUUC-Pop-098928	Populus trichocarpa	35.14	2.00e-98	353.00
IUUC-Pca-100987	Procavia capensis	85.13	0.00e+00	859.00
IUUC-Ppe-102040	Prunus persica	37.27	1.00e-95	344.00
IUUC-Pva-103034	Pteropus vampyrus	88.14	0.00e+00	1807.00
IUUC-Pgr-103513	Puccinia graminis	39.06	1.00e-105	378.00
IUUC-Ptt-103967	Puccinia triticina	41.41	5.00e-94	339.00
IUUC-Pte-104105	Pyrenophora teres	34.09	3.00e-81	297.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	37.15	6.00e-78	286.00
IUUC-Rno-105380	Rattus norvegicus	88.99	0.00e+00	1691.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.01	7.00e-68	252.00
IUUC-Sha-107108	Sarcophilus harrisii	82.78	0.00e+00	1756.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	40.25	4.00e-96	345.00
IUUC-Spo-108097	Schizosaccharomyces pombe	44.12	5.00e-94	339.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	29.74	8.00e-83	302.00
IUUC-Sar-113687	Sorex araneus	82.30	0.00e+00	910.00
IUUC-Sre-115038	Sporisorium reilianum	43.76	7.00e-99	355.00
IUUC-Ssc-116168	Sus scrofa	88.47	0.00e+00	821.00
IUUC-Tgu-116729	Taeniopygia guttata	89.31	0.00e+00	1924.00
IUUC-Tru-118068	Takifugu rubripes	76.01	0.00e+00	1594.00
IUUC-Tsy-118942	Tarsius syrichta	90.34	0.00e+00	699.00
IUUC-Tni-120732	Tetraodon nigroviridis	75.07	0.00e+00	1551.00
IUUC-Tre-121892	Trichoderma reesei	36.93	1.00e-87	318.00
IUUC-Tvi-122354	Trichoderma virens	35.69	4.00e-88	320.00
IUUC-Tme-127102	Tuber melanosporum	35.65	8.00e-91	328.00
IUUC-Tbe-127351	Tupaia belangeri	79.88	0.00e+00	1499.00
IUUC-Ttr-129061	Tursiops truncatus	90.59	0.00e+00	1897.00
IUUC-Uma-129343	Ustilago maydis	44.47	2.00e-99	357.00
IUUC-Vda-129748	Verticillium dahliae	38.60	7.00e-80	292.00
IUUC-Vvi-131234	Vitis vinifera	35.74	9.00e-102	365.00
IUUC-Xtr-132094	Xenopus tropicalis	84.81	0.00e+00	1774.00
IUUC-Xma-133923	Xiphophorus maculatus	77.53	0.00e+00	1655.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence