iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053902

UUCD1 version

UUC-LoA-00513

Ensembl Protein ID

ENSLAFP00000012285.4

UniProt Accession

G3TDM9; G3TDM9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000014668.4	ENSLAFT00000014670.4	ENSLAFP00000012285.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.00e-114	382.3	703	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 703  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 787
           7899********************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di++lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 788  EGIVVDVPFASFFLSQLLGHhhsifYSSVDELPSLDSEFYKNLTSIKRY-DGDISDLGLTLSY--DEDVMGQLVCHELIPGGKTIPV 871
           ********************777777999********************.7799998777776..5999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Yv+l++++r++++ik+q++a+ +Gf+++i++e++++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 872  TNENKISYVHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 958
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ +er++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+Y
   Q: 959  ILaSDFTPDERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPNY 1045
           **99*************************************************************8888****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k++l+ekL+yAi++++gFels
   Q: 1046 SKKSVLREKLRYAISMNTGFELS 1068
           ********************985 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MFTVSQTSRA WFIDKARQAR EERLVQKERE RAAVEIQAHV RSFLCRSRLQ REIRREIDEF 60
FNADDSGSSK RSALCIFKIA RKLLFLFRIK EDNERLEKLC RCILSSMDAE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTACCG TGTCTCAGAC CTCGAGGGCA TGGTTCATCG ATAAAGCCCG CCAGGCCCGA 60
GAAGAAAGAT TGGTTCAAAA GGAGCGGGAG CGGGCAGCTG TTGAGATTCA GGCCCACGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

lav:100656625

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.86	3.00e-106	380.00
IUUC-Aml-002107	Ailuropoda melanoleuca	97.19	0.00e+00	2109.00
IUUC-Atr-003017	Amborella trichopoda	38.19	8.00e-110	392.00
IUUC-Apl-003328	Anas platyrhynchos	89.34	0.00e+00	1880.00
IUUC-Aly-005794	Arabidopsis lyrata	38.82	6.00e-109	389.00
IUUC-Ath-007269	Arabidopsis thaliana	39.18	1.00e-111	398.00
IUUC-Ago-007748	Ashbya gossypii	38.39	2.00e-67	251.00
IUUC-Acl-008158	Aspergillus clavatus	31.98	7.00e-61	229.00
IUUC-Afl-008398	Aspergillus flavus	32.72	7.00e-64	239.00
IUUC-Afu-008937	Aspergillus fumigatus	31.77	4.00e-62	233.00
IUUC-Ani-009252	Aspergillus nidulans	32.79	2.00e-68	254.00
IUUC-Ang-009773	Aspergillus niger	30.16	7.00e-65	242.00
IUUC-Aor-009940	Aspergillus oryzae	32.72	8.00e-64	239.00
IUUC-Ate-010395	Aspergillus terreus	32.72	1.00e-63	238.00
IUUC-Bgr-012269	Blumeria graminis	35.25	1.00e-61	230.00
IUUC-Bta-013547	Bos taurus	96.16	0.00e+00	2111.00
IUUC-Bci-013743	Botrytis cinerea	34.36	8.00e-70	259.00
IUUC-Bdi-014502	Brachypodium distachyon	39.32	3.00e-110	393.00
IUUC-Bol-015093	Brassica oleracea	39.89	4.00e-113	402.00
IUUC-Bra-016722	Brassica rapa	39.89	6.00e-114	405.00
IUUC-Cel-018447	Caenorhabditis elegans	38.19	0.00e+00	690.00
IUUC-Cja-019855	Callithrix jacchus	96.54	0.00e+00	2094.00
IUUC-Cfa-020066	Canis familiaris	96.88	0.00e+00	2084.00
IUUC-Cpo-021504	Cavia porcellus	95.04	0.00e+00	2084.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	36.57	1.00e-75	278.00
IUUC-Csa-023579	Chlorocebus sabaeus	96.35	0.00e+00	2092.00
IUUC-Cho-024430	Choloepus hoffmanni	86.54	0.00e+00	1564.00
IUUC-Cin-025750	Ciona intestinalis	47.16	0.00e+00	976.00
IUUC-Csv-026016	Ciona savignyi	47.85	0.00e+00	1025.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.79	3.00e-73	270.00
IUUC-Cne-026841	Cryptococcus neoformans	37.67	2.00e-71	264.00
IUUC-Cme-027265	Cyanidioschyzon merolae	41.24	1.00e-89	324.00
IUUC-Dre-028271	Danio rerio	82.43	0.00e+00	1781.00
IUUC-Dno-029054	Dasypus novemcinctus	97.28	0.00e+00	2115.00
IUUC-Dor-030938	Dipodomys ordii	87.92	0.00e+00	1873.00
IUUC-Dse-031416	Dothistroma septosporum	34.83	3.00e-66	247.00
IUUC-Dme-031602	Drosophila melanogaster	48.52	0.00e+00	974.00
IUUC-Ete-033041	Echinops telfairi	76.92	0.00e+00	1384.00
IUUC-Eca-034411	Equus caballus	97.19	0.00e+00	2085.00
IUUC-Eeu-035201	Erinaceus europaeus	84.70	0.00e+00	808.00
IUUC-Fca-036594	Felis catus	95.60	0.00e+00	2053.00
IUUC-Fal-037317	Ficedula albicollis	85.47	0.00e+00	1888.00
IUUC-Fox-037788	Fusarium oxysporum	31.92	8.00e-78	285.00
IUUC-Fso-038088	Fusarium solani	31.75	2.00e-75	277.00
IUUC-Gmo-039412	Gadus morhua	77.93	0.00e+00	1739.00
IUUC-Ggr-039941	Gaeumannomyces graminis	34.40	6.00e-72	266.00
IUUC-Gga-040149	Gallus gallus	89.44	0.00e+00	1918.00
IUUC-Gac-042088	Gasterosteus aculeatus	81.23	0.00e+00	1833.00
IUUC-Gma-043839	Glycine max	39.89	1.00e-112	400.00
IUUC-Ggo-045279	Gorilla gorilla	96.35	0.00e+00	2088.00
IUUC-Hsa-045660	Homo sapiens	96.16	0.00e+00	2085.00
IUUC-Hvu-047102	Hordeum vulgare	39.68	9.00e-106	378.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	93.79	0.00e+00	1059.00
IUUC-Kpa-049307	Komagataella pastoris	32.74	1.00e-64	241.00
IUUC-Lch-050664	Latimeria chalumnae	83.29	0.00e+00	1847.00
IUUC-Lpe-050755	Leersia perrieri	37.46	5.00e-99	355.00
IUUC-Loc-052791	Lepisosteus oculatus	83.61	0.00e+00	1804.00
IUUC-Lma-053096	Leptosphaeria maculans	35.88	3.00e-69	257.00
IUUC-Mcc-054730	Macaca mulatta	96.25	0.00e+00	2091.00
IUUC-Meu-056527	Macropus eugenii	80.41	0.00e+00	1692.00
IUUC-Mor-057021	Magnaporthe oryzae	36.21	1.00e-62	235.00
IUUC-Mpo-057570	Magnaporthe poae	34.17	1.00e-68	255.00
IUUC-Mtr-057671	Medicago truncatula	39.89	7.00e-113	402.00
IUUC-Mla-059124	Melampsora laricipopulina	38.98	8.00e-78	284.00
IUUC-Mga-059260	Meleagris gallopavo	88.99	0.00e+00	1914.00
IUUC-Mvi-060445	Microbotryum violaceum	35.52	4.00e-86	313.00
IUUC-Mmr-060804	Microcebus murinus	95.04	0.00e+00	2021.00
IUUC-Mdo-062575	Monodelphis domestica	84.69	0.00e+00	1804.00
IUUC-Mmu-063636	Mus musculus	91.78	0.00e+00	1955.00
IUUC-Mac-064989	Musa acuminata	39.25	4.00e-107	383.00
IUUC-Mpu-066677	Mustela putorius furo	96.62	0.00e+00	1973.00
IUUC-Mlu-067952	Myotis lucifugus	95.70	0.00e+00	2011.00
IUUC-Nfi-068280	Neosartorya fischeri	31.98	1.00e-62	235.00
IUUC-Ncr-068869	Neurospora crassa	32.24	2.00e-70	261.00
IUUC-Nle-069153	Nomascus leucogenys	96.35	0.00e+00	2086.00
IUUC-Opr-070554	Ochotona princeps	94.18	0.00e+00	1873.00
IUUC-Ont-071372	Oreochromis niloticus	82.23	0.00e+00	1810.00
IUUC-Oan-073327	Ornithorhynchus anatinus	72.54	0.00e+00	756.00
IUUC-Ocu-074183	Oryctolagus cuniculus	94.39	0.00e+00	2041.00
IUUC-Oba-075213	Oryza barthii	38.99	5.00e-107	382.00
IUUC-Obr-076320	Oryza brachyantha	39.61	7.00e-110	392.00
IUUC-Ogl-077093	Oryza glaberrima	39.17	1.00e-109	391.00
IUUC-Ogu-078947	Oryza glumaepatula	36.81	7.00e-110	392.00
IUUC-Oin-080058	Oryza indica	39.27	2.00e-109	390.00
IUUC-Olo-080742	Oryza longistaminata	38.99	2.00e-108	387.00
IUUC-Ome-081741	Oryza meridionalis	38.87	6.00e-102	365.00
IUUC-Oni-082385	Oryza nivara	36.81	6.00e-110	392.00
IUUC-Opu-083529	Oryza punctata	39.17	2.00e-109	390.00
IUUC-Oru-085128	Oryza rufipogon	37.55	6.00e-96	345.00
IUUC-Osa-085557	Oryza sativa	39.27	4.00e-109	389.00
IUUC-Ola-087337	Oryzias latipes	81.29	0.00e+00	1746.00
IUUC-Olu-087699	Ostreococcus lucimarinus	41.03	6.00e-80	290.00
IUUC-Oga-088342	Otolemur garnettii	95.32	0.00e+00	1986.00
IUUC-Oar-090234	Ovis aries	96.03	0.00e+00	2084.00
IUUC-Ptr-091661	Pan troglodytes	96.35	0.00e+00	2090.00
IUUC-Pan-092728	Papio anubis	96.07	0.00e+00	2086.00
IUUC-Psi-093251	Pelodiscus sinensis	88.78	0.00e+00	1770.00
IUUC-Pma-094195	Petromyzon marinus	69.83	0.00e+00	1455.00
IUUC-Pno-095132	Phaeosphaeria nodorum	33.92	4.00e-52	199.00
IUUC-Ppa-095544	Physcomitrella patens	38.20	2.00e-111	397.00
IUUC-Pfo-097472	Poecilia formosa	81.67	0.00e+00	1815.00
IUUC-Pab-098570	Pongo abelii	96.16	0.00e+00	2086.00
IUUC-Pop-098928	Populus trichocarpa	35.01	6.00e-98	352.00
IUUC-Pca-100110	Procavia capensis	85.30	0.00e+00	1780.00
IUUC-Ppe-101281	Prunus persica	38.90	3.00e-107	383.00
IUUC-Pva-102887	Pteropus vampyrus	91.77	0.00e+00	1955.00
IUUC-Pgr-103513	Puccinia graminis	34.21	8.00e-77	282.00
IUUC-Ptt-103967	Puccinia triticina	32.50	5.00e-67	249.00
IUUC-Pte-104105	Pyrenophora teres	33.56	6.00e-73	269.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	35.46	1.00e-69	258.00
IUUC-Rno-106028	Rattus norvegicus	88.89	0.00e+00	1860.00
IUUC-Sce-106446	Saccharomyces cerevisiae	36.05	3.00e-56	213.00
IUUC-Sha-107331	Sarcophilus harrisii	85.82	0.00e+00	1833.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	38.05	6.00e-81	295.00
IUUC-Spo-108097	Schizosaccharomyces pombe	33.73	3.00e-83	303.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.49	2.00e-69	257.00
IUUC-Smo-109488	Selaginella moellendorffii	37.12	7.00e-106	378.00
IUUC-Sit-109811	Setaria italica	35.75	2.00e-110	394.00
IUUC-Sly-111362	Solanum lycopersicum	35.19	5.00e-101	362.00
IUUC-Sar-113287	Sorex araneus	86.42	0.00e+00	736.00
IUUC-Sbi-114433	Sorghum bicolor	35.66	2.00e-111	397.00
IUUC-Sre-115038	Sporisorium reilianum	39.07	7.00e-82	299.00
IUUC-Ssc-116103	Sus scrofa	97.19	0.00e+00	2076.00
IUUC-Tgu-117275	Taeniopygia guttata	88.69	0.00e+00	1900.00
IUUC-Tru-118681	Takifugu rubripes	80.82	0.00e+00	1823.00
IUUC-Tsy-118985	Tarsius syrichta	91.38	0.00e+00	1042.00
IUUC-Tni-120850	Tetraodon nigroviridis	91.23	0.00e+00	776.00
IUUC-Tca-121770	Theobroma cacao	39.43	6.00e-112	399.00
IUUC-Tre-121892	Trichoderma reesei	36.83	2.00e-77	284.00
IUUC-Tvi-122354	Trichoderma virens	36.67	3.00e-80	293.00
IUUC-Tae-125466	Triticum aestivum	36.66	5.00e-108	385.00
IUUC-Tur-126086	Triticum urartu	39.86	1.00e-105	378.00
IUUC-Tme-127102	Tuber melanosporum	32.39	3.00e-81	296.00
IUUC-Tbe-127461	Tupaia belangeri	91.39	0.00e+00	1906.00
IUUC-Ttr-129269	Tursiops truncatus	96.16	0.00e+00	2056.00
IUUC-Uma-129343	Ustilago maydis	39.07	7.00e-84	305.00
IUUC-Vda-129748	Verticillium dahliae	33.19	1.00e-62	234.00
IUUC-Vpa-130523	Vicugna pacos	77.96	1.00e-129	457.00
IUUC-Vvi-131524	Vitis vinifera	38.93	7.00e-109	388.00
IUUC-Xtr-132146	Xenopus tropicalis	84.79	0.00e+00	1862.00
IUUC-Xma-133526	Xiphophorus maculatus	81.38	0.00e+00	1806.00
IUUC-Yli-134496	Yarrowia lipolytica	34.65	4.00e-70	259.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence