iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072800

UUCD1 version

UUC-OrA-00015

Ensembl Protein ID

ENSOANP00000009801.1

UniProt Accession

F6PLU9; F6PLU9_ORNAN

Protein Name

Uncharacterized protein

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006137.2	ENSOANT00000009803.2	ENSOANP00000009801.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.40e-107	358.0	747	1084

Active Site

Position(s)	Description	Evidence
1052	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal++
   Q: 747  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-SFARHYYFLGRMLGKALYE 832
           689**********99**9************************************9999999999965.999**************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++++f+++llg+  ++++++l+++dpe+yk+l ++k++ e+d+eelgl++t+   ++ lge++++eLkpgG++ipVt +N
   Q: 833  NMLVELPFASFFLSKLLGTsaDVDIHHLASLDPEMYKNLLFLKSY-EDDVEELGLNFTV--VNNDLGEAQVVELKPGGKDIPVTSAN 916
           ******************9666889********************.6788887666665..5889********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i++++ afr+G+ +v++le+l++F+++e+++li+G    i+++dlk++t+y ggy++d+p+i+ Fw+v+e+
   Q: 917  RIAYIHLVADYRLNKQIRQHCLAFRQGLANVVNLEWLRMFDQQEIQVLISGAqVPISLDDLKSFTNYSGGYSADHPVIKIFWRVVES 1003
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd drlP+++TC+n+LkLPe+  ++ l++kLlyAie ++gFels
   Q: 1004 FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlDRLPTASTCMNLLKLPEFYDENLLRSKLLYAIECAAGFELS 1084
           ****************************88.*****99999**************************************985 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLGGAS RKEEKASLLH RTQEERRKRE EERRRLKNAI IIQSFVRGYR 60
DRKQQYSIQR SEFDRWANLA QSGGTFSIAS GSNLTLLARQ LLFFYRQNED SKRLIWMCQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNTCTGCATC AGCAGCAGCT 60
TCTTTCTCCC TTCAATCTCC CCCTCCGGGC AGATCAGGGC CCCTTCTCCG CCCCCCCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

KEGG

oaa:100074194

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	35.96	2.00e-93	337.00
IUUC-Aml-001355	Ailuropoda melanoleuca	89.00	0.00e+00	1845.00
IUUC-Atr-002669	Amborella trichopoda	35.63	2.00e-101	363.00
IUUC-Apl-003731	Anas platyrhynchos	95.39	0.00e+00	2004.00
IUUC-Aca-005248	Anolis carolinensis	93.73	0.00e+00	2010.00
IUUC-Aly-005768	Arabidopsis lyrata	35.03	2.00e-111	396.00
IUUC-Ath-006576	Arabidopsis thaliana	34.88	6.00e-111	395.00
IUUC-Ago-007748	Ashbya gossypii	41.43	6.00e-79	288.00
IUUC-Acl-008158	Aspergillus clavatus	37.95	3.00e-76	280.00
IUUC-Afl-008398	Aspergillus flavus	37.87	5.00e-78	285.00
IUUC-Afu-008937	Aspergillus fumigatus	38.85	2.00e-79	290.00
IUUC-Ani-009252	Aspergillus nidulans	38.17	5.00e-80	292.00
IUUC-Ang-009773	Aspergillus niger	33.91	2.00e-79	290.00
IUUC-Aor-009940	Aspergillus oryzae	37.87	5.00e-78	285.00
IUUC-Ate-010395	Aspergillus terreus	34.26	3.00e-80	293.00
IUUC-Ame-010769	Astyanax mexicanus	63.25	0.00e+00	1047.00
IUUC-Bgr-012269	Blumeria graminis	38.43	8.00e-76	276.00
IUUC-Bta-012841	Bos taurus	87.83	0.00e+00	1850.00
IUUC-Bci-013743	Botrytis cinerea	29.64	1.00e-86	314.00
IUUC-Bdi-014123	Brachypodium distachyon	47.06	2.00e-104	373.00
IUUC-Bol-015390	Brassica oleracea	46.84	1.00e-103	370.00
IUUC-Bra-016853	Brassica rapa	34.76	2.00e-110	393.00
IUUC-Cel-018638	Caenorhabditis elegans	40.10	6.00e-92	331.00
IUUC-Cja-019743	Callithrix jacchus	88.95	0.00e+00	1848.00
IUUC-Cfa-021031	Canis familiaris	90.72	0.00e+00	1904.00
IUUC-Cpo-022401	Cavia porcellus	89.76	0.00e+00	1878.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.50	2.00e-86	311.00
IUUC-Csa-024107	Chlorocebus sabaeus	90.31	0.00e+00	1920.00
IUUC-Cho-024750	Choloepus hoffmanni	81.67	0.00e+00	790.00
IUUC-Cin-025432	Ciona intestinalis	45.39	2.00e-99	355.00
IUUC-Csv-026016	Ciona savignyi	33.33	9.00e-94	337.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.49	1.00e-88	320.00
IUUC-Cne-026841	Cryptococcus neoformans	36.12	8.00e-96	344.00
IUUC-Cme-027265	Cyanidioschyzon merolae	47.58	7.00e-106	377.00
IUUC-Dre-028196	Danio rerio	78.32	0.00e+00	1610.00
IUUC-Dno-029024	Dasypus novemcinctus	91.79	0.00e+00	1931.00
IUUC-Dor-030483	Dipodomys ordii	89.30	0.00e+00	675.00
IUUC-Dse-031416	Dothistroma septosporum	34.59	3.00e-81	296.00
IUUC-Dme-031946	Drosophila melanogaster	37.63	0.00e+00	696.00
IUUC-Ete-032240	Echinops telfairi	79.33	5.00e-173	601.00
IUUC-Eca-033828	Equus caballus	90.87	0.00e+00	1885.00
IUUC-Eeu-034604	Erinaceus europaeus	83.08	2.00e-124	439.00
IUUC-Fca-035907	Felis catus	89.85	0.00e+00	1908.00
IUUC-Fal-037389	Ficedula albicollis	95.39	0.00e+00	2035.00
IUUC-Fox-037788	Fusarium oxysporum	36.89	4.00e-90	325.00
IUUC-Fso-038088	Fusarium solani	36.01	2.00e-88	320.00
IUUC-Gmo-039254	Gadus morhua	67.76	0.00e+00	1254.00
IUUC-Ggr-039941	Gaeumannomyces graminis	33.62	1.00e-83	304.00
IUUC-Gga-040310	Gallus gallus	94.65	0.00e+00	2018.00
IUUC-Gac-042054	Gasterosteus aculeatus	70.73	0.00e+00	1305.00
IUUC-Gma-042836	Glycine max	35.89	6.00e-103	368.00
IUUC-Ggo-045031	Gorilla gorilla	90.68	0.00e+00	1927.00
IUUC-Hsa-045880	Homo sapiens	90.59	0.00e+00	1926.00
IUUC-Hvu-047770	Hordeum vulgare	48.04	5.00e-106	377.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	79.91	2.00e-180	624.00
IUUC-Kpa-049307	Komagataella pastoris	36.99	6.00e-67	248.00
IUUC-Lch-050403	Latimeria chalumnae	84.27	0.00e+00	1720.00
IUUC-Lpe-051428	Leersia perrieri	46.40	8.00e-97	347.00
IUUC-Loc-052218	Lepisosteus oculatus	83.33	0.00e+00	1726.00
IUUC-Lma-053096	Leptosphaeria maculans	38.36	4.00e-81	296.00
IUUC-Laf-054162	Loxodonta africana	87.69	0.00e+00	1640.00
IUUC-Mcc-055127	Macaca mulatta	90.41	0.00e+00	1920.00
IUUC-Meu-056187	Macropus eugenii	83.48	4.00e-107	382.00
IUUC-Mor-057021	Magnaporthe oryzae	34.03	2.00e-80	293.00
IUUC-Mpo-057570	Magnaporthe poae	37.12	2.00e-77	283.00
IUUC-Mtr-058154	Medicago truncatula	35.28	3.00e-105	375.00
IUUC-Mla-059124	Melampsora laricipopulina	48.28	8.00e-103	366.00
IUUC-Mga-059581	Meleagris gallopavo	94.43	0.00e+00	2001.00
IUUC-Mvi-060445	Microbotryum violaceum	38.40	2.00e-105	376.00
IUUC-Mmr-061360	Microcebus murinus	86.96	0.00e+00	1768.00
IUUC-Mdo-062194	Monodelphis domestica	91.31	0.00e+00	2003.00
IUUC-Mmu-064189	Mus musculus	88.84	0.00e+00	1896.00
IUUC-Mac-065275	Musa acuminata	49.88	8.00e-111	394.00
IUUC-Mpu-066439	Mustela putorius furo	88.58	0.00e+00	1841.00
IUUC-Mlu-068228	Myotis lucifugus	86.06	0.00e+00	1825.00
IUUC-Nfi-068280	Neosartorya fischeri	39.07	4.00e-80	292.00
IUUC-Ncr-068869	Neurospora crassa	35.61	2.00e-83	303.00
IUUC-Nle-069687	Nomascus leucogenys	89.83	0.00e+00	1864.00
IUUC-Opr-070592	Ochotona princeps	95.00	2.00e-111	396.00
IUUC-Ont-071836	Oreochromis niloticus	79.98	0.00e+00	1686.00
IUUC-Ocu-074587	Oryctolagus cuniculus	91.33	0.00e+00	1927.00
IUUC-Oba-075006	Oryza barthii	49.39	4.00e-109	389.00
IUUC-Obr-076133	Oryza brachyantha	48.90	2.00e-108	387.00
IUUC-Ogl-077003	Oryza glaberrima	49.39	2.00e-109	389.00
IUUC-Ogu-078947	Oryza glumaepatula	49.39	2.00e-109	390.00
IUUC-Oin-079407	Oryza indica	45.48	1.00e-95	343.00
IUUC-Olo-080475	Oryza longistaminata	49.39	2.00e-109	390.00
IUUC-Ome-081342	Oryza meridionalis	46.40	7.00e-97	348.00
IUUC-Oni-082385	Oryza nivara	49.39	2.00e-109	390.00
IUUC-Opu-083176	Oryza punctata	49.39	3.00e-109	389.00
IUUC-Oru-084554	Oryza rufipogon	46.40	9.00e-97	347.00
IUUC-Osa-085355	Oryza sativa	49.39	2.00e-109	390.00
IUUC-Ola-087209	Oryzias latipes	79.43	0.00e+00	1646.00
IUUC-Olu-087699	Ostreococcus lucimarinus	43.13	2.00e-89	321.00
IUUC-Oga-088776	Otolemur garnettii	85.33	0.00e+00	1743.00
IUUC-Oar-089441	Ovis aries	87.20	0.00e+00	1829.00
IUUC-Ptr-091273	Pan troglodytes	90.50	0.00e+00	1924.00
IUUC-Pan-091981	Papio anubis	90.31	0.00e+00	1921.00
IUUC-Psi-093203	Pelodiscus sinensis	94.82	0.00e+00	1764.00
IUUC-Pma-094738	Petromyzon marinus	64.96	0.00e+00	1335.00
IUUC-Pno-095132	Phaeosphaeria nodorum	34.42	6.00e-58	218.00
IUUC-Ppa-095682	Physcomitrella patens	37.33	6.00e-115	408.00
IUUC-Pfo-097511	Poecilia formosa	79.89	0.00e+00	1694.00
IUUC-Pab-098634	Pongo abelii	87.65	0.00e+00	1845.00
IUUC-Pop-099574	Populus trichocarpa	41.86	8.00e-94	338.00
IUUC-Pca-100987	Procavia capensis	84.49	0.00e+00	848.00
IUUC-Ppe-102040	Prunus persica	34.88	9.00e-98	351.00
IUUC-Pva-103034	Pteropus vampyrus	84.65	0.00e+00	1737.00
IUUC-Pgr-103513	Puccinia graminis	39.11	7.00e-107	381.00
IUUC-Ptt-103967	Puccinia triticina	41.53	5.00e-95	342.00
IUUC-Pte-104105	Pyrenophora teres	37.72	3.00e-79	290.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	37.50	4.00e-79	289.00
IUUC-Rno-105380	Rattus norvegicus	87.54	0.00e+00	1631.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.49	3.00e-70	259.00
IUUC-Sha-107108	Sarcophilus harrisii	87.85	0.00e+00	1845.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	44.39	3.00e-97	349.00
IUUC-Spo-108097	Schizosaccharomyces pombe	44.85	1.00e-96	347.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	28.89	6.00e-84	305.00
IUUC-Smo-109537	Selaginella moellendorffii	36.57	3.00e-104	372.00
IUUC-Sit-110457	Setaria italica	49.26	1.00e-101	363.00
IUUC-Sly-111362	Solanum lycopersicum	35.44	2.00e-102	367.00
IUUC-Sar-113687	Sorex araneus	80.38	0.00e+00	894.00
IUUC-Sbi-113882	Sorghum bicolor	47.79	3.00e-98	352.00
IUUC-Sre-115038	Sporisorium reilianum	43.98	2.00e-97	350.00
IUUC-Ssc-116168	Sus scrofa	81.76	0.00e+00	740.00
IUUC-Tgu-116729	Taeniopygia guttata	94.65	0.00e+00	2016.00
IUUC-Tru-118068	Takifugu rubripes	77.58	0.00e+00	1624.00
IUUC-Tsy-118942	Tarsius syrichta	88.89	0.00e+00	699.00
IUUC-Tni-120732	Tetraodon nigroviridis	76.91	0.00e+00	1593.00
IUUC-Tca-121737	Theobroma cacao	35.69	7.00e-109	387.00
IUUC-Tre-121892	Trichoderma reesei	36.23	4.00e-87	315.00
IUUC-Tvi-122354	Trichoderma virens	35.50	3.00e-88	319.00
IUUC-Tae-125466	Triticum aestivum	47.79	2.00e-105	376.00
IUUC-Tur-126086	Triticum urartu	36.30	4.00e-93	335.00
IUUC-Tme-127102	Tuber melanosporum	36.06	6.00e-94	338.00
IUUC-Tbe-127351	Tupaia belangeri	78.79	0.00e+00	1451.00
IUUC-Ttr-129061	Tursiops truncatus	86.99	0.00e+00	1811.00
IUUC-Uma-129343	Ustilago maydis	44.94	2.00e-99	357.00
IUUC-Vda-129748	Verticillium dahliae	38.60	2.00e-81	297.00
IUUC-Vvi-131234	Vitis vinifera	35.63	3.00e-105	376.00
IUUC-Xtr-132094	Xenopus tropicalis	88.67	0.00e+00	1871.00
IUUC-Xma-133923	Xiphophorus maculatus	80.07	0.00e+00	1697.00
IUUC-Yli-134496	Yarrowia lipolytica	40.04	7.00e-91	327.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence