iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092885

Ensembl Protein ID

ENSPANP00000000433.1

UniProt Accession

A0A096MLK4; A0A096MLK4_PAPAN

Genbank Protein ID

ENSPANP00000000433

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01036304

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000005453.1	ENSPANT00000004440.1	ENSPANP00000000433.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	5.10e-09	36.1	4	42
ULD/UDP/UFD/UBX	3.90e-20	72.2	210	291

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ +  +dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 210  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 291
           578*****************************************************************************98 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLETPLGHIL 60
GREPTSSEQG GLEGSGSAAG EGKPILSEEE RQEQTKRMLE LVAQKQRERE EREEREALER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCCCGCGG AAGCGGCGGT GTCGGCGCCA TGGCGGAGCT GACGGCTCTT GAGAGTCTCA 60
TCGAGATGGG CTTCCCCAGG GGACGCGCGT AAGGGAGTTC CCCAACCCCG GCCTGCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002325	Ailuropoda melanoleuca	93.20	9.00e-115	405.00
IUUC-Aca-004329	Anolis carolinensis	71.43	3.00e-48	184.00
IUUC-Aly-005639	Arabidopsis lyrata	50.91	6.00e-12	65.10
IUUC-Ath-006887	Arabidopsis thaliana	41.67	5.00e-12	65.50
IUUC-Ago-007989	Ashbya gossypii	37.18	9.00e-07	47.40
IUUC-Ame-011399	Astyanax mexicanus	53.09	9.00e-61	226.00
IUUC-Bta-013151	Bos taurus	93.92	3.00e-118	417.00
IUUC-Bdi-014311	Brachypodium distachyon	54.55	1.00e-09	57.40
IUUC-Bol-016537	Brassica oleracea	50.91	1.00e-11	64.30
IUUC-Bra-017906	Brassica rapa	59.09	2.00e-11	63.90
IUUC-Cel-018300	Caenorhabditis elegans	34.85	4.00e-13	68.60
IUUC-Cja-019084	Callithrix jacchus	98.94	2.00e-106	379.00
IUUC-Cfa-020997	Canis familiaris	89.79	2.00e-91	328.00
IUUC-Cpo-021736	Cavia porcellus	78.79	2.00e-81	295.00
IUUC-Csa-024040	Chlorocebus sabaeus	100.00	3.00e-105	374.00
IUUC-Cho-024543	Choloepus hoffmanni	96.04	3.00e-65	241.00
IUUC-Cin-025719	Ciona intestinalis	39.12	4.00e-36	144.00
IUUC-Csv-025854	Ciona savignyi	37.33	6.00e-35	140.00
IUUC-Cme-027235	Cyanidioschyzon merolae	47.73	4.00e-08	52.80
IUUC-Dre-027745	Danio rerio	51.66	2.00e-58	218.00
IUUC-Dno-029598	Dasypus novemcinctus	93.94	6.00e-106	376.00
IUUC-Dor-030917	Dipodomys ordii	82.39	1.00e-90	326.00
IUUC-Dme-032055	Drosophila melanogaster	43.64	2.00e-23	102.00
IUUC-Ete-032960	Echinops telfairi	74.82	5.00e-72	264.00
IUUC-Eca-034294	Equus caballus	94.61	9.00e-109	385.00
IUUC-Eeu-034906	Erinaceus europaeus	90.53	4.00e-99	353.00
IUUC-Fca-035653	Felis catus	91.55	8.00e-98	349.00
IUUC-Gmo-038755	Gadus morhua	49.03	4.00e-53	201.00
IUUC-Gac-042481	Gasterosteus aculeatus	54.84	7.00e-58	217.00
IUUC-Ggo-044821	Gorilla gorilla	98.59	5.00e-98	350.00
IUUC-Hsa-046797	Homo sapiens	98.99	2.00e-106	378.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	95.29	3.00e-116	410.00
IUUC-Lch-049508	Latimeria chalumnae	67.37	5.00e-33	134.00
IUUC-Laf-053932	Loxodonta africana	95.29	1.00e-125	442.00
IUUC-Mcc-055300	Macaca mulatta	99.66	4.00e-105	374.00
IUUC-Mtr-058774	Medicago truncatula	50.00	8.00e-10	57.40
IUUC-Mvi-060245	Microbotryum violaceum	40.48	3.00e-12	65.50
IUUC-Mmr-060979	Microcebus murinus	94.95	2.00e-109	388.00
IUUC-Mdo-062299	Monodelphis domestica	86.27	1.00e-92	332.00
IUUC-Mmu-063212	Mus musculus	93.94	1.00e-111	395.00
IUUC-Mac-065072	Musa acuminata	60.53	1.00e-10	60.50
IUUC-Mpu-066540	Mustela putorius furo	93.94	4.00e-117	414.00
IUUC-Mlu-067589	Myotis lucifugus	90.91	1.00e-106	379.00
IUUC-Nle-069045	Nomascus leucogenys	97.63	6.00e-78	283.00
IUUC-Opr-070772	Ochotona princeps	87.25	1.00e-88	319.00
IUUC-Ont-072006	Oreochromis niloticus	54.14	5.00e-58	217.00
IUUC-Oan-073244	Ornithorhynchus anatinus	87.34	8.00e-36	143.00
IUUC-Ocu-074333	Oryctolagus cuniculus	95.29	2.00e-107	381.00
IUUC-Oba-075451	Oryza barthii	50.94	4.00e-11	62.40
IUUC-Obr-076923	Oryza brachyantha	55.10	2.00e-11	63.50
IUUC-Ogl-077259	Oryza glaberrima	38.36	4.00e-10	59.30
IUUC-Ogu-078589	Oryza glumaepatula	50.94	4.00e-11	62.40
IUUC-Oin-079151	Oryza indica	50.94	4.00e-11	62.40
IUUC-Ome-081253	Oryza meridionalis	50.94	4.00e-11	62.40
IUUC-Oni-082110	Oryza nivara	38.36	1.00e-10	60.50
IUUC-Opu-083336	Oryza punctata	50.94	5.00e-11	62.40
IUUC-Oru-085235	Oryza rufipogon	50.94	4.00e-11	62.40
IUUC-Osa-085611	Oryza sativa	50.94	4.00e-11	62.40
IUUC-Ola-086781	Oryzias latipes	54.69	1.00e-55	209.00
IUUC-Oga-088429	Otolemur garnettii	96.63	6.00e-107	380.00
IUUC-Oar-089885	Ovis aries	93.58	2.00e-118	418.00
IUUC-Ptr-091315	Pan troglodytes	98.24	7.00e-98	350.00
IUUC-Psi-093299	Pelodiscus sinensis	71.90	8.00e-63	233.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	60.10
IUUC-Pfo-096188	Poecilia formosa	53.57	5.00e-55	207.00
IUUC-Pab-097881	Pongo abelii	92.26	2.00e-103	368.00
IUUC-Pop-098863	Populus trichocarpa	52.94	9.00e-12	64.70
IUUC-Pca-100977	Procavia capensis	93.97	1.00e-99	356.00
IUUC-Ppe-101243	Prunus persica	47.06	8.00e-10	57.80
IUUC-Pva-102169	Pteropus vampyrus	95.42	6.00e-101	360.00
IUUC-Rno-105459	Rattus norvegicus	93.27	5.00e-111	393.00
IUUC-Sha-107526	Sarcophilus harrisii	88.55	8.00e-92	330.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	25.74	1.00e-05	44.30
IUUC-Sit-110434	Setaria italica	37.80	2.00e-09	56.60
IUUC-Sar-112945	Sorex araneus	93.51	9.00e-66	243.00
IUUC-Sbi-114159	Sorghum bicolor	33.33	3.00e-10	59.30
IUUC-Ssc-116114	Sus scrofa	95.62	7.00e-104	370.00
IUUC-Tru-117839	Takifugu rubripes	52.27	3.00e-53	201.00
IUUC-Tsy-118813	Tarsius syrichta	73.24	7.00e-94	337.00
IUUC-Tni-120504	Tetraodon nigroviridis	53.95	3.00e-54	205.00
IUUC-Tbe-128034	Tupaia belangeri	95.42	1.00e-107	382.00
IUUC-Ttr-128468	Tursiops truncatus	89.19	2.00e-105	375.00
IUUC-Uma-129569	Ustilago maydis	34.62	1.00e-05	43.50
IUUC-Vpa-130179	Vicugna pacos	89.18	1.00e-71	262.00
IUUC-Xtr-132119	Xenopus tropicalis	63.09	1.00e-69	256.00
IUUC-Xma-134067	Xiphophorus maculatus	52.92	2.00e-55	208.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence