iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-016637

Ensembl Protein ID

Bra038022.1-P

UniProt Accession

M4FAA8; M4FAA8_BRARP

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra038022	Bra038022.1	Bra038022.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.50e-121	405.1	3315	3653
UBD/Alpha-Helix/UBM	1.50e-14	54.1	2615	2640

Active Site

Position(s)	Description	Evidence
3621	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksf 96
           +dl+ rl+v+f+gEeg+d+gG+tre+++l+s+ ++++ + lf ++ ++++t+qpnp+s ++n ehl++F+f+Gr+++kal+dg+lld+ +++sf
   Q: 3315 QDLRGRLNVQFQGEEGVDAGGLTREWYQLVSRVIFDKGALLF-TTVGNDATFQPNPNSVYQN-EHLSYFKFVGRMVAKALFDGQLLDVYFTRSF 3406
           7999**********************************9999.556678889******9977.******************************* PP
   S: 97   yklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseei.......lgetkeeeLkpgGenipVtneNkeeYvklvveyrlk 183
           yk++lg+k++++d+e+vdp++yk+lk+++en   d++++ ldltfs++ ++         e++++eLkp+G+ni+Vt+e k+eYv+lv+ ++l+
   Q: 3407 YKHILGVKVTYHDIEAVDPDYYKNLKWLLEN---DVSDI-LDLTFSMDADEekhilyeKTEVTDYELKPRGRNIRVTEETKHEYVDLVAGHILT 3496
           *****************************99...88887.88888866666668895555566778**************************** PP
   S: 184  egikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlg 277
           + i+ q++af eGfne+ip el+s+F+ +elelli+G +eid++dlk++t+y++ yt+ sp+i+wFwev+++fs+e+ ++fLqFvTg+s++Pl+
   Q: 3497 NAIRPQINAFLEGFNELIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYTS-YTAGSPVIHWFWEVVKAFSKEDMARFLQFVTGTSKVPLE 3589
           ****************************************************99.*************************************** PP
   S: 278  Gfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           Gf++l+    p++ +i+k ++ ++rlPs++TCfn+L+LPeY+ske+l+e+Ll+Ai+e+ +gF++
   Q: 3590 GFKALQgisgPQRLQIHKaYGGPERLPSAHTCFNQLDLPEYPSKEQLEERLLLAIHEAsEGFGF 3653
           ******************999*****************************************86 PP

UBD/Alpha-Helix/UBM

   S: 3    sqvDpeVfsqLPeeiQeEvmaelrqq 28
           +++Dpe++++LP++iQ Ev+a +r+q
   Q: 2615 EDIDPEFLAALPPDIQTEVLAQQRVQ 2640
           79**********************98 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MPSQVQPPKI KSFINSVTAV PLDQIQEPLS CFHWDFDDKG DFHHWVDLFN HFDTYFEKHI 60
KARKDLHVEQ QDSEDESTPP LPKDALLQIL RVIRVVLDNC TNIHFFTSYE QHLSLLLAST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTTCCC AAGTCGTAAG TTTTCTAATT AAACCCTAAA TCAATTTGGA TTACCAGCGG 60
TTACCTCTTC TTTCTTTGGC ATATATCTTT GTTTTTATTC TTTTTATTAA TTGATATATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR003903--UIM_dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50330--UIM

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001684	Ailuropoda melanoleuca	50.78	6.00e-126	447.00
IUUC-Atr-003044	Amborella trichopoda	52.67	0.00e+00	1926.00
IUUC-Aca-005263	Anolis carolinensis	51.00	2.00e-126	449.00
IUUC-Aly-006083	Arabidopsis lyrata	82.78	0.00e+00	5480.00
IUUC-Ath-007472	Arabidopsis thaliana	82.76	0.00e+00	5610.00
IUUC-Ame-011067	Astyanax mexicanus	50.55	2.00e-124	442.00
IUUC-Bta-012813	Bos taurus	50.78	6.00e-126	447.00
IUUC-Cja-018741	Callithrix jacchus	50.89	4.00e-125	444.00
IUUC-Cfa-020083	Canis familiaris	50.78	7.00e-126	446.00
IUUC-Csa-023853	Chlorocebus sabaeus	50.78	7.00e-126	446.00
IUUC-Cho-024718	Choloepus hoffmanni	54.45	8.00e-117	416.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	32.76	3.00e-145	511.00
IUUC-Cne-027095	Cryptococcus neoformans	40.00	5.00e-109	390.00
IUUC-Dre-028525	Danio rerio	48.92	1.00e-110	396.00
IUUC-Dno-029680	Dasypus novemcinctus	50.78	6.00e-126	447.00
IUUC-Dor-030902	Dipodomys ordii	45.43	1.00e-106	383.00
IUUC-Dme-032122	Drosophila melanogaster	49.18	3.00e-119	425.00
IUUC-Eca-033915	Equus caballus	50.45	3.00e-124	441.00
IUUC-Eeu-034963	Erinaceus europaeus	50.44	9.00e-124	440.00
IUUC-Fca-035824	Felis catus	50.78	6.00e-126	447.00
IUUC-Gmo-039073	Gadus morhua	50.78	5.00e-126	447.00
IUUC-Gga-040309	Gallus gallus	57.32	4.00e-98	350.00
IUUC-Gac-042430	Gasterosteus aculeatus	50.78	4.00e-126	447.00
IUUC-Gma-044247	Glycine max	59.75	0.00e+00	3717.00
IUUC-Hsa-046879	Homo sapiens	50.78	6.00e-126	447.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	50.78	4.00e-126	446.00
IUUC-Lch-050252	Latimeria chalumnae	50.89	2.00e-125	445.00
IUUC-Lpe-050915	Leersia perrieri	47.46	0.00e+00	1834.00
IUUC-Loc-052472	Lepisosteus oculatus	50.56	1.00e-125	446.00
IUUC-Laf-054154	Loxodonta africana	50.78	7.00e-126	447.00
IUUC-Mcc-055085	Macaca mulatta	50.78	8.00e-126	446.00
IUUC-Mor-057201	Magnaporthe oryzae	33.16	5.00e-142	500.00
IUUC-Mtr-058088	Medicago truncatula	59.20	0.00e+00	3789.00
IUUC-Mmr-060820	Microcebus murinus	50.78	6.00e-126	447.00
IUUC-Mdo-062930	Monodelphis domestica	50.78	3.00e-126	448.00
IUUC-Mmu-063601	Mus musculus	50.78	6.00e-126	447.00
IUUC-Mac-065557	Musa acuminata	48.91	0.00e+00	1351.00
IUUC-Mpu-066653	Mustela putorius furo	50.78	6.00e-126	447.00
IUUC-Mlu-067418	Myotis lucifugus	50.78	4.00e-126	447.00
IUUC-Nle-069418	Nomascus leucogenys	50.78	6.00e-126	447.00
IUUC-Ont-071300	Oreochromis niloticus	50.78	7.00e-126	447.00
IUUC-Oan-073046	Ornithorhynchus anatinus	50.55	8.00e-125	443.00
IUUC-Ocu-074178	Oryctolagus cuniculus	50.78	3.00e-126	447.00
IUUC-Oba-075252	Oryza barthii	50.49	0.00e+00	2954.00
IUUC-Obr-076762	Oryza brachyantha	50.31	0.00e+00	1769.00
IUUC-Ogl-077590	Oryza glaberrima	52.28	0.00e+00	1043.00
IUUC-Ogu-077981	Oryza glumaepatula	48.85	0.00e+00	1793.00
IUUC-Oin-079663	Oryza indica	48.85	0.00e+00	1885.00
IUUC-Olo-080326	Oryza longistaminata	48.58	0.00e+00	1837.00
IUUC-Oni-082342	Oryza nivara	50.49	0.00e+00	2976.00
IUUC-Opu-083428	Oryza punctata	50.33	0.00e+00	1711.00
IUUC-Oru-084559	Oryza rufipogon	50.49	0.00e+00	2947.00
IUUC-Osa-086200	Oryza sativa	62.29	0.00e+00	1174.00
IUUC-Oga-088903	Otolemur garnettii	50.78	6.00e-126	447.00
IUUC-Oar-090210	Ovis aries	50.78	8.00e-126	446.00
IUUC-Pan-092368	Papio anubis	49.16	1.00e-111	399.00
IUUC-Ppa-095657	Physcomitrella patens	45.62	0.00e+00	1543.00
IUUC-Pfo-096232	Poecilia formosa	50.78	4.00e-126	447.00
IUUC-Pab-098583	Pongo abelii	50.78	6.00e-126	447.00
IUUC-Pop-099520	Populus trichocarpa	60.70	0.00e+00	3857.00
IUUC-Pca-100596	Procavia capensis	43.04	1.00e-84	307.00
IUUC-Ppe-102109	Prunus persica	61.93	0.00e+00	3984.00
IUUC-Pva-102116	Pteropus vampyrus	46.65	7.00e-111	397.00
IUUC-Sha-106961	Sarcophilus harrisii	50.78	5.00e-126	447.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	33.46	2.00e-136	481.00
IUUC-Spo-108024	Schizosaccharomyces pombe	33.27	1.00e-138	489.00
IUUC-Smo-109428	Selaginella moellendorffii	43.13	0.00e+00	1432.00
IUUC-Sit-110149	Setaria italica	49.06	0.00e+00	1731.00
IUUC-Sly-111285	Solanum lycopersicum	58.38	0.00e+00	3777.00
IUUC-Stu-112501	Solanum tuberosum	66.40	1.00e-132	465.00
IUUC-Sar-113291	Sorex araneus	51.67	2.00e-120	429.00
IUUC-Sbi-113794	Sorghum bicolor	47.11	0.00e+00	1514.00
IUUC-Ssc-115754	Sus scrofa	50.78	6.00e-126	447.00
IUUC-Tru-118570	Takifugu rubripes	50.78	3.00e-126	448.00
IUUC-Tni-120836	Tetraodon nigroviridis	50.56	1.00e-123	439.00
IUUC-Tca-121646	Theobroma cacao	64.14	0.00e+00	2392.00
IUUC-Ttr-129253	Tursiops truncatus	50.78	1.00e-125	446.00
IUUC-Vpa-130708	Vicugna pacos	50.78	1.00e-125	446.00
IUUC-Vvi-131559	Vitis vinifera	63.23	0.00e+00	1621.00
IUUC-Xtr-132123	Xenopus tropicalis	48.57	8.00e-114	407.00
IUUC-Xma-133869	Xiphophorus maculatus	50.78	3.00e-126	448.00
IUUC-Yli-134657	Yarrowia lipolytica	32.61	3.00e-146	514.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence