iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-36	123.0	435	469
UBD/Beta-Prp	1.10e-60	205.4	346	550

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH + v++++f ++  ++++Gs D+t+k+WDlr+ 
   Q: 435  GHLGAVFGVDFsPNgFHIATGSQDNTCKIWDLRRR 469
           8***********77799**************9875 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsl 100
           + + gh+ +++++v+f+p++++lat+++d++ ++wd+++++ +   +gh ++v ++++++dg++lvtg+ D++ +vwdl+tg c++ l+gh   v  +
   Q: 346  ADITGHMPHRVSKVAFHPSGRFLATACYDSSWRLWDLEQKTEVLHQEGHAKPVHCLSYHSDGSVLVTGGLDAFGRVWDLRTGRCIMFLEGHLGAVFGV 443
           56889********************************************************************************************* PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvs 197
           +fsp+g ++++Gs+d+t ++wdl+ +q ++ t   h+ +++ v++++++ + lv++s+D+t ++W+ kt + l+tl+g h+++v s+++ +n++++++
   Q: 444  DFSPNGFHIATGSQDNTCKIWDLRRRQPVY-TIPAHTNLISDVKYQQECgSFLVTCSYDSTTKIWSNKTWQPLKTLQG-HDNKVISVDIAPNSQYIAT 539
           ******************************.9*********************************************9.******************* PP
   S: 198  gsldgtvklwd 208
            s d+t klw+
   Q: 540  TSFDRTFKLWS 550
           **********7 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSDDDDIQYI KRQRTLHYGS LEESERKRQN AAASGAAATT TSGTTASSGA GTTTTGTGGQ 60
LEDIDSDEDY EESTKKTSNA KQAGAPPPTA ATLANKIDDD YFDLEMEMER DKVALLEEFE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCTCGGCG TTGCTCAACA CTAGGCAGCA AAACGTTTTC TTTACGGCAA TATTTTTTGT 60
TGTTTCTTCG TTGTTTCGGC GAAATTTTAT TTTAAAATTA ATTATTTTGC ACTTGTTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR014906--PRP4-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08799--PRP4
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00500--SFM
SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0030532--C:small nuclear ribonucleoprotein complex
GO:0046540--C:U4/U6 x U5 tri-snRNP complex
GO:0030621--F:U4 snRNA binding
GO:0017070--F:U6 snRNA binding
GO:0000398--P:mRNA splicing, via spliceosome

KEGG

dme:Dmel_CG6322

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000498	Aegilops tauschii	42.82	1.00e-78	286.00
IUUC-Aml-001737	Ailuropoda melanoleuca	56.89	6.00e-149	520.00
IUUC-Atr-002828	Amborella trichopoda	42.60	1.00e-91	329.00
IUUC-Apl-003723	Anas platyrhynchos	56.96	6.00e-150	523.00
IUUC-Aca-004972	Anolis carolinensis	56.86	6.00e-145	506.00
IUUC-Aly-006531	Arabidopsis lyrata	38.22	2.00e-76	279.00
IUUC-Ath-007367	Arabidopsis thaliana	40.36	9.00e-89	320.00
IUUC-Ago-007893	Ashbya gossypii	34.17	6.00e-52	197.00
IUUC-Acl-008236	Aspergillus clavatus	37.14	3.00e-76	278.00
IUUC-Afl-008522	Aspergillus flavus	37.73	1.00e-85	309.00
IUUC-Afu-008904	Aspergillus fumigatus	35.56	1.00e-79	290.00
IUUC-Ani-009198	Aspergillus nidulans	38.48	4.00e-87	314.00
IUUC-Ang-009662	Aspergillus niger	39.96	1.00e-83	302.00
IUUC-Aor-009881	Aspergillus oryzae	37.73	1.00e-85	309.00
IUUC-Ate-010333	Aspergillus terreus	36.10	1.00e-75	276.00
IUUC-Ame-011697	Astyanax mexicanus	57.91	6.00e-149	520.00
IUUC-Bgr-012254	Blumeria graminis	36.75	4.00e-88	318.00
IUUC-Bta-012615	Bos taurus	56.89	6.00e-149	520.00
IUUC-Bci-013720	Botrytis cinerea	35.78	2.00e-85	309.00
IUUC-Bdi-014302	Brachypodium distachyon	42.73	1.00e-91	329.00
IUUC-Bol-015594	Brassica oleracea	39.38	6.00e-80	290.00
IUUC-Bra-017465	Brassica rapa	39.16	3.00e-80	291.00
IUUC-Cel-018632	Caenorhabditis elegans	43.06	9.00e-101	359.00
IUUC-Cja-019747	Callithrix jacchus	56.89	2.00e-149	521.00
IUUC-Cfa-020288	Canis familiaris	56.89	3.00e-149	520.00
IUUC-Cpo-021440	Cavia porcellus	56.19	3.00e-147	514.00
IUUC-Cre-022716	Chlamydomonas reinhardtii	42.42	9.00e-75	273.00
IUUC-Csa-023139	Chlorocebus sabaeus	58.18	2.00e-110	391.00
IUUC-Cho-024481	Choloepus hoffmanni	56.54	1.00e-144	504.00
IUUC-Cin-025106	Ciona intestinalis	54.88	2.00e-139	488.00
IUUC-Csv-026087	Ciona savignyi	53.15	5.00e-134	470.00
IUUC-Cgl-026538	Colletotrichum gloeosporioides	34.56	1.00e-81	297.00
IUUC-Cne-026793	Cryptococcus neoformans	38.71	6.00e-87	313.00
IUUC-Dre-028723	Danio rerio	58.94	9.00e-145	506.00
IUUC-Dno-029299	Dasypus novemcinctus	57.11	1.00e-149	522.00
IUUC-Dor-030345	Dipodomys ordii	43.50	4.00e-38	151.00
IUUC-Dse-031562	Dothistroma septosporum	33.61	1.00e-76	280.00
IUUC-Ete-032669	Echinops telfairi	56.74	3.00e-150	524.00
IUUC-Eca-033566	Equus caballus	56.89	7.00e-149	519.00
IUUC-Eeu-034524	Erinaceus europaeus	61.00	2.00e-82	298.00
IUUC-Fca-036215	Felis catus	56.89	4.00e-149	520.00
IUUC-Fal-037018	Ficedula albicollis	57.79	2.00e-129	454.00
IUUC-Fox-037936	Fusarium oxysporum	34.86	9.00e-77	280.00
IUUC-Fso-038366	Fusarium solani	35.73	1.00e-83	303.00
IUUC-Gmo-038966	Gadus morhua	53.67	6.00e-102	363.00
IUUC-Ggr-039942	Gaeumannomyces graminis	35.94	2.00e-76	278.00
IUUC-Gga-040797	Gallus gallus	56.96	8.00e-150	522.00
IUUC-Gac-042598	Gasterosteus aculeatus	54.57	2.00e-128	451.00
IUUC-Gma-044220	Glycine max	42.83	2.00e-89	322.00
IUUC-Ggo-044682	Gorilla gorilla	57.30	4.00e-148	517.00
IUUC-Hsa-045804	Homo sapiens	56.89	4.00e-149	520.00
IUUC-Hvu-047567	Hordeum vulgare	44.24	1.00e-81	295.00
IUUC-Itr-047882	Ictidomys tridecemlineatus	56.89	4.00e-149	520.00
IUUC-Kpa-049369	Komagataella pastoris	37.31	6.00e-55	207.00
IUUC-Lch-050074	Latimeria chalumnae	49.37	9.00e-142	496.00
IUUC-Lpe-051333	Leersia perrieri	42.42	1.00e-82	298.00
IUUC-Loc-052164	Lepisosteus oculatus	56.80	3.00e-148	517.00
IUUC-Lma-053088	Leptosphaeria maculans	34.89	4.00e-75	275.00
IUUC-Laf-053460	Loxodonta africana	56.89	3.00e-149	521.00
IUUC-Mcc-055859	Macaca mulatta	56.89	4.00e-149	520.00
IUUC-Meu-056134	Macropus eugenii	56.46	2.00e-146	511.00
IUUC-Mor-057251	Magnaporthe oryzae	35.74	5.00e-79	287.00
IUUC-Mpo-057375	Magnaporthe poae	38.65	2.00e-53	201.00
IUUC-Mtr-057656	Medicago truncatula	43.32	4.00e-79	287.00
IUUC-Mla-059145	Melampsora laricipopulina	39.13	3.00e-87	314.00
IUUC-Mga-059855	Meleagris gallopavo	57.17	3.00e-150	524.00
IUUC-Mvi-060372	Microbotryum violaceum	40.85	1.00e-79	289.00
IUUC-Mmr-060826	Microcebus murinus	56.24	3.00e-148	517.00
IUUC-Mdo-062119	Monodelphis domestica	56.46	4.00e-146	510.00
IUUC-Mmu-063351	Mus musculus	56.89	7.00e-149	519.00
IUUC-Mac-064846	Musa acuminata	41.88	2.00e-81	295.00
IUUC-Mpu-066006	Mustela putorius furo	56.89	4.00e-149	520.00
IUUC-Mlu-067398	Myotis lucifugus	56.46	2.00e-148	518.00
IUUC-Nfi-068399	Neosartorya fischeri	35.56	4.00e-85	307.00
IUUC-Ncr-068711	Neurospora crassa	36.38	6.00e-85	307.00
IUUC-Nle-069982	Nomascus leucogenys	56.89	2.00e-149	521.00
IUUC-Opr-070596	Ochotona princeps	56.89	3.00e-149	520.00
IUUC-Ont-072374	Oreochromis niloticus	50.45	6.00e-139	486.00
IUUC-Oan-073166	Ornithorhynchus anatinus	56.01	2.00e-124	437.00
IUUC-Ocu-074371	Oryctolagus cuniculus	56.89	6.00e-149	520.00
IUUC-Oba-075083	Oryza barthii	41.50	8.00e-85	306.00
IUUC-Obr-076405	Oryza brachyantha	41.07	3.00e-80	291.00
IUUC-Ogl-077683	Oryza glaberrima	41.50	8.00e-85	306.00
IUUC-Ogu-078486	Oryza glumaepatula	41.27	2.00e-83	302.00
IUUC-Oin-079679	Oryza indica	41.04	1.00e-87	317.00
IUUC-Olo-080243	Oryza longistaminata	42.00	3.00e-74	271.00
IUUC-Ome-081230	Oryza meridionalis	41.04	1.00e-87	316.00
IUUC-Oni-082961	Oryza nivara	41.04	9.00e-88	316.00
IUUC-Opu-083189	Oryza punctata	41.27	7.00e-84	303.00
IUUC-Oru-084353	Oryza rufipogon	41.49	9.00e-86	309.00
IUUC-Osa-085458	Oryza sativa	41.04	1.00e-87	316.00
IUUC-Ola-086940	Oryzias latipes	56.67	1.00e-142	498.00
IUUC-Olu-087580	Ostreococcus lucimarinus	34.26	1.00e-55	210.00
IUUC-Oga-088703	Otolemur garnettii	53.83	4.00e-139	487.00
IUUC-Oar-089829	Ovis aries	56.89	4.00e-149	520.00
IUUC-Ptr-090838	Pan troglodytes	56.89	4.00e-149	520.00
IUUC-Pan-092261	Papio anubis	56.77	8.00e-148	516.00
IUUC-Psi-093020	Pelodiscus sinensis	57.33	5.00e-150	523.00
IUUC-Pno-094858	Phaeosphaeria nodorum	35.57	8.00e-72	263.00
IUUC-Ppa-095531	Physcomitrella patens	40.08	3.00e-93	335.00
IUUC-Pfo-096812	Poecilia formosa	46.50	8.00e-121	426.00
IUUC-Pab-097805	Pongo abelii	52.44	5.00e-120	423.00
IUUC-Pop-100051	Populus trichocarpa	42.63	1.00e-85	309.00
IUUC-Pca-100152	Procavia capensis	56.67	4.00e-149	520.00
IUUC-Ppe-101244	Prunus persica	44.34	8.00e-92	329.00
IUUC-Pva-102529	Pteropus vampyrus	55.14	1.00e-146	512.00
IUUC-Pgr-103550	Puccinia graminis	35.01	7.00e-90	323.00
IUUC-Ptt-103951	Puccinia triticina	32.88	3.00e-73	268.00
IUUC-Pte-104151	Pyrenophora teres	35.41	5.00e-73	267.00
IUUC-Pyt-104571	Pyrenophora triticirepentis	35.19	4.00e-73	268.00
IUUC-Rno-105747	Rattus norvegicus	56.89	1.00e-148	518.00
IUUC-Sce-106418	Saccharomyces cerevisiae	32.95	3.00e-61	228.00
IUUC-Sha-107334	Sarcophilus harrisii	56.46	2.00e-146	511.00
IUUC-Sja-107794	Schizosaccharomyces japonicus	34.00	2.00e-66	245.00
IUUC-Spo-108189	Schizosaccharomyces pombe	35.63	3.00e-72	265.00
IUUC-Ssl-108550	Sclerotinia sclerotiorum	35.34	3.00e-85	308.00
IUUC-Smo-108924	Selaginella moellendorffii	42.89	2.00e-92	332.00
IUUC-Sit-110102	Setaria italica	41.31	1.00e-85	309.00
IUUC-Sly-111668	Solanum lycopersicum	44.02	9.00e-92	329.00
IUUC-Stu-111928	Solanum tuberosum	44.24	2.00e-92	332.00
IUUC-Sar-113266	Sorex araneus	50.22	6.00e-126	443.00
IUUC-Sbi-114134	Sorghum bicolor	41.76	3.00e-86	311.00
IUUC-Sre-115114	Sporisorium reilianum	38.31	1.00e-82	299.00
IUUC-Ssc-115443	Sus scrofa	56.89	6.00e-149	520.00
IUUC-Tgu-117157	Taeniopygia guttata	57.17	1.00e-150	525.00
IUUC-Tru-118587	Takifugu rubripes	56.67	3.00e-139	487.00
IUUC-Tsy-119157	Tarsius syrichta	56.92	4.00e-125	441.00
IUUC-Tni-120427	Tetraodon nigroviridis	56.60	8.00e-139	486.00
IUUC-Tca-121368	Theobroma cacao	42.66	1.00e-91	330.00
IUUC-Tre-122074	Trichoderma reesei	34.62	1.00e-81	296.00
IUUC-Tvi-122349	Trichoderma virens	33.90	3.00e-79	288.00
IUUC-Tae-123589	Triticum aestivum	42.89	1.00e-81	296.00
IUUC-Tur-125983	Triticum urartu	47.30	4.00e-71	260.00
IUUC-Tme-126951	Tuber melanosporum	38.08	4.00e-83	301.00
IUUC-Tbe-128136	Tupaia belangeri	52.30	5.00e-136	476.00
IUUC-Ttr-129169	Tursiops truncatus	53.82	2.00e-82	298.00
IUUC-Uma-129399	Ustilago maydis	37.96	1.00e-79	289.00
IUUC-Vda-129842	Verticillium dahliae	35.27	2.00e-84	305.00
IUUC-Vpa-130440	Vicugna pacos	56.67	2.00e-149	521.00
IUUC-Vvi-131075	Vitis vinifera	44.59	1.00e-93	336.00
IUUC-Xtr-132713	Xenopus tropicalis	34.87	3.00e-46	178.00
IUUC-Xma-133002	Xiphophorus maculatus	59.78	4.00e-115	406.00
IUUC-Yli-134569	Yarrowia lipolytica	35.31	4.00e-71	261.00
IUUC-Zma-135799	Zea mays	38.89	8.00e-85	306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence