iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132608

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ring finger protein 5; Ring finger protein 5, E3 ubiquitin protein ligase

Genbank Nucleotide ID

AAMC01112964

Gene Name

rnf5; TGas109g15.1-001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000027728.1	ENSXETT00000020841.2	ENSXETP00000020841.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.20e-06	26.9	11	66
E3 activity/RING/RING	7.10e-08	33.0	14	55

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggk..tcPvtrqplteedlvPn 58
           ++ C I le  r+Pvv+ +G+ y   ++++wl++     +cPv+++ ++ e+++P 
   Q: 11   AYECNICLETAREPVVSVCGHLYCWPCLHQWLETRPDrqECPVCKAGISREKVIPI 66
           789*****************************6665556**************997 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iCle  ++ p+v  CgH+++  Cl++w         ++ CP+C+
   Q: 14   CNICLETARE-PVVSVCGHLYCWPCLHQW---LETRPDRQECPVCK 55
           99******88.999***************...556889999****7 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MAAAAGSPGA AYECNICLET AREPVVSVCG HLYCWPCLHQ WLETRPDRQE CPVCKAGISR 60
EKVIPIYGRG DSNQKDPRLK TPPRPQGQRP EPENRAGGGV PGFTDTGFHM SFGIGAFPFG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGATCGGTT GCCATGGCGG CGGCTGCTGG CAGCCCCGGT GCGGCTTATG AGTGTAATAT 60
CTGCTTGGAG ACAGCGCGGG AACCTGTTGT CAGTGTGTGT GGGCATTTGT ACTGGTGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0044390--F:ubiquitin-like protein conjugating enzyme binding
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

xtr:549825

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001155	Aegilops tauschii	49.45	1.00e-23	103.00
IUUC-Aml-001417	Ailuropoda melanoleuca	80.83	1.00e-53	202.00
IUUC-Aly-005785	Arabidopsis lyrata	54.76	2.00e-24	105.00
IUUC-Ath-007401	Arabidopsis thaliana	54.76	1.00e-24	106.00
IUUC-Ame-011316	Astyanax mexicanus	80.67	3.00e-55	207.00
IUUC-Bta-013109	Bos taurus	80.00	7.00e-53	199.00
IUUC-Bdi-014313	Brachypodium distachyon	49.45	2.00e-23	102.00
IUUC-Cja-019902	Callithrix jacchus	79.17	4.00e-52	196.00
IUUC-Cfa-020079	Canis familiaris	80.00	3.00e-53	200.00
IUUC-Cpo-021320	Cavia porcellus	74.80	1.00e-48	185.00
IUUC-Csa-023595	Chlorocebus sabaeus	79.17	2.00e-52	197.00
IUUC-Dre-027716	Danio rerio	72.38	3.00e-41	160.00
IUUC-Dor-030170	Dipodomys ordii	80.83	3.00e-53	200.00
IUUC-Dme-031966	Drosophila melanogaster	53.90	3.00e-42	165.00
IUUC-Eca-033642	Equus caballus	80.83	1.00e-53	201.00
IUUC-Eeu-034778	Erinaceus europaeus	73.15	4.00e-40	155.00
IUUC-Fca-036326	Felis catus	81.67	9.00e-55	205.00
IUUC-Gac-042258	Gasterosteus aculeatus	81.51	3.00e-55	207.00
IUUC-Ggo-045474	Gorilla gorilla	80.00	6.00e-53	199.00
IUUC-Hsa-046046	Homo sapiens	80.00	5.00e-53	199.00
IUUC-Itr-048037	Ictidomys tridecemlineatus	80.00	4.00e-53	199.00
IUUC-Laf-053395	Loxodonta africana	80.83	2.00e-53	201.00
IUUC-Mcc-054833	Macaca mulatta	79.17	2.00e-52	197.00
IUUC-Meu-055984	Macropus eugenii	76.12	2.00e-29	120.00
IUUC-Mvi-060316	Microbotryum violaceum	50.85	8.00e-13	67.00
IUUC-Mdo-062437	Monodelphis domestica	73.28	2.00e-53	201.00
IUUC-Mmu-064159	Mus musculus	80.00	3.00e-53	200.00
IUUC-Mac-065053	Musa acuminata	57.14	5.00e-24	104.00
IUUC-Mlu-067689	Myotis lucifugus	77.50	5.00e-52	196.00
IUUC-Nle-069705	Nomascus leucogenys	80.00	5.00e-53	199.00
IUUC-Ont-072482	Oreochromis niloticus	82.35	1.00e-56	211.00
IUUC-Ocu-074208	Oryctolagus cuniculus	80.00	6.00e-53	199.00
IUUC-Olo-080378	Oryza longistaminata	40.29	4.00e-23	101.00
IUUC-Ola-086507	Oryzias latipes	81.51	3.00e-56	210.00
IUUC-Olu-087623	Ostreococcus lucimarinus	54.24	2.00e-16	78.60
IUUC-Oga-088912	Otolemur garnettii	80.83	2.00e-53	201.00
IUUC-Oar-090284	Ovis aries	80.00	4.00e-53	200.00
IUUC-Ptr-090919	Pan troglodytes	80.00	5.00e-53	199.00
IUUC-Pan-092843	Papio anubis	79.17	2.00e-52	197.00
IUUC-Pfo-096818	Poecilia formosa	67.88	5.00e-61	226.00
IUUC-Pab-098244	Pongo abelii	80.00	6.00e-53	199.00
IUUC-Pop-099595	Populus trichocarpa	60.47	5.00e-28	117.00
IUUC-Pca-100319	Procavia capensis	80.00	3.00e-53	200.00
IUUC-Pva-102249	Pteropus vampyrus	77.78	2.00e-50	191.00
IUUC-Rno-106042	Rattus norvegicus	80.00	3.00e-53	200.00
IUUC-Smo-109663	Selaginella moellendorffii	50.47	3.00e-24	103.00
IUUC-Sly-110917	Solanum lycopersicum	52.33	1.00e-25	109.00
IUUC-Stu-112552	Solanum tuberosum	52.33	3.00e-25	108.00
IUUC-Ssc-115934	Sus scrofa	80.83	2.00e-53	201.00
IUUC-Tru-118679	Takifugu rubripes	63.86	1.00e-24	105.00
IUUC-Tsy-119615	Tarsius syrichta	80.83	6.00e-54	202.00
IUUC-Tca-121830	Theobroma cacao	57.65	1.00e-25	109.00
IUUC-Tae-124319	Triticum aestivum	49.45	2.00e-23	102.00
IUUC-Tur-126198	Triticum urartu	49.45	2.00e-23	102.00
IUUC-Tbe-127773	Tupaia belangeri	79.17	2.00e-50	191.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence